Clinical trials
Periodontitis clinical trials
Below are recruiting periodontitis clinical trials, each written for real people, not researchers. We’re tracking 281 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06654141Recruiting
Healing time and tooth socket preservation after molar extraction
This study looks at how different healing times affect the success of preserving the bone where a molar is removed due to gum disease. It aims to find the best wait time before placing a dental implant.
ShanghaiAges 18 years+ - NCT06685016Recruiting
Study of dental health after IPR with clear aligners
This study looks at how the teeth and gums are doing after a common orthodontic step called IPR (a slight smoothing between teeth) in people wearing clear aligners. It will help understand if this procedure keeps your mouth healthy.
NaplesAges 17–100 - NCT06781229Recruiting
Gum bacteria in people preparing for weight loss surgery
This trial looks at the bacteria in the mouths of people with a BMI of 30 or higher who are scheduled for weight-loss surgery. The goal is to understand how gum health and body weight are connected.
ToulouseAges 18 years+ - NCT06782035Recruiting
Effect of dressings on donor site comfort after gum graft surgery
This trial tests whether special dressings applied to the area where a gum graft is taken from can improve patient comfort and quality of life after surgery.
IzmirAges 18–85 - NCT06808373Recruiting
Hypnosis for gum disease treatment
This study tests whether hypnosis can help with gum disease treatment. It is for adults who have chronic gum disease but are otherwise healthy.
AfyonkarahisarAges 20–65 - NCT06830200Recruiting
Treating infected dental implants with a chitosan brush
This study tests a new treatment for infected dental implants using a small brush made of chitosan (a natural material from shellfish). It aims to clean the implant surface and help the infection heal.
AnkaraAges 18–65 - NCT06843525Recruiting
Bite force measurements for molar dental work
This trial measures how your bite force changes after getting a filling or root canal on a lower back tooth. It helps doctors understand if different dental treatments affect your ability to chew.
Newark, New JerseyAges 18–89 - NCT06914596Recruiting
Comparing an at-home gum treatment to standard care after deep cleaning
This study tests if a device you use at home for 30 minutes twice a day can improve gum healing after a deep cleaning (scaling and root planing). Participants will have their gum health compared to a group that receives standard care.
Fullerton, CaliforniaAges 30–75 - NCT06934291Recruiting
Comparing ultrasonic tools for deep gum cleaning
This trial tests two types of ultrasonic tools (piezoelectric vs magnetostrictive) for full-mouth deep gum cleaning in people with mild to moderate gum disease (periodontitis stages 1 and 2). It aims to see which tool works better for removing plaque and tartar.
Siena, SIAges 18–80 - NCT07018284Recruiting
Pain after root canal filling with different sealers
This study compares pain levels after root canal treatment using two different types of sealer material. It aims to find which sealer may cause less discomfort.
MadridAges 18 years+ - NCT07019298Recruiting
Comparing dental filling methods for root canals
This trial studies different ways to fill a root canal after treatment to see which works best. It may help if you have a tooth with an infected or dying nerve.
Madrid, SpainAges 18 years+ - NCT07048028Recruiting
Chitosan rinse for root canals in premolars
This study tests a new natural mouth rinse (chitosan) during root canal treatment for lower premolar teeth. Researchers want to see if it helps clean the tooth better than standard treatment.
Ordu, AltınorduAges 18 years+ - NCT07053969Recruiting
Does a protein gel thicken gum tissue around implants?
This study tests whether a protein-based gel (enamel matrix derivative) can make the gum tissue thicker during a second-stage implant procedure. It may help people getting dental implants achieve better healing and gum support.
San Antonio, TexasAges 18–18 - NCT07141680Recruiting
Replantation vs splinting for loose lower front teeth
This study compares putting a loose lower front tooth back in place and splinting it (replantation) versus splinting alone. It's for people with severe gum disease that has caused bone loss and tooth looseness.
IstanbulAges 18–65 - NCT07180498Recruiting
Tea tree vs chlorhexidine mouthwash after wisdom tooth removal
This study compares a tea tree oil mouthwash and a standard chlorhexidine mouthwash to see which helps better after wisdom tooth removal. It may help you heal faster and with less discomfort.
SanliurfaAges 18–65 - NCT07205172Recruiting
Gum looks and teeth crowding in children
This study looks at how the appearance of the gums relates to crowding of teeth in children. It will examine kids in different stages of tooth development to see if there is a link.
RomaAges 5–16 - NCT07205588Recruiting
Dental health check using digital tools
This study uses digital tools to assess dental problems in adults who are new to a dental practice or haven't visited in the last six months. It aims to understand how well these tools work for finding dental issues.
ChâtillonAges 18 years+ - NCT07237620Recruiting
Comparing medicines for failed root canal treatment
This trial compares different medicines placed inside the tooth after a failed root canal to help heal the infection at the root tip. If you have a back tooth that still has an infection even though it had a root canal years ago, this study may test which medicine works best for you.
Hatay, AntakyaAges 18–60 - NCT07292870Recruiting
Biological treatments for deep gum bone defects
This trial tests whether biological agents can help heal deep gum bone defects that remain after standard non-surgical cleaning. It may be an option for people who still have deep pockets around their teeth and need a minimally invasive surgical procedure.
Leuven, Vlaams BrabantAges 18 years+ - NCT07296965Recruiting
Oral bacteria in carotid artery plaque study
This study looks at the bacteria living in your mouth and whether they are linked to plaque buildup in the carotid artery (the main artery in your neck). If you are already scheduled for surgery to remove that plaque, the researchers will take samples from your mouth and the plaque to compare them.
BudapestAges 18 years+ - NCT07297836Recruiting
Dentist practices for treating baby teeth in France
This study surveys dentists in France about how they treat non-vital (nerve-damaged) baby teeth. It aims to understand current professional practices.
StrasbourgAges 18 years+ - NCT07310212Recruiting
Comparing two root canal techniques for pain and success
This study compares two methods of filling a root canal after cleaning it: a traditional lateral condensation technique and a newer warm vertical obturation technique. The goal is to see which one causes less pain afterward and has a better success rate.
Amman, Amman GovernateAges 18 years+ - NCT07343804Recruiting
Dental root canal and heart disease risk study
This trial tests whether treating a tooth infection with a root canal can lower blood markers linked to heart risk in people with stable heart disease.
Rohtak, HaryanaAges 30 years+ - NCT07349056Recruiting
Early effects of jaw surgery on gum health
This trial looks at how jaw surgery affects your gums and supporting tissues over six months. It may help if you have certain jaw misalignments need surgery.
EdirneAges 18–65
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Common questions
- Are there clinical trials for periodontitis?
- Yes. Clin2 currently lists 281 recruiting periodontitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a periodontitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a periodontitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.