Clinical trials
Periodontitis clinical trials
Below are recruiting periodontitis clinical trials, each written for real people, not researchers. We’re tracking 271 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06654141Recruiting
Healing time and tooth socket preservation after molar extraction
This study looks at how different healing times affect the success of preserving the bone where a molar is removed due to gum disease. It aims to find the best wait time before placing a dental implant.
ShanghaiAges 18 years+ - NCT07388901Recruiting
Comparing two root canal sealers for infection treatment
This trial compares two materials (iRoot SP and nRoot SP) used to fill root canals after infection. It aims to see which works better for healing apical periodontitis, an infection around the tooth root.
Hangzhou, ZhejiangAges 18 years+ - NCT07372677Recruiting
Pocket-X gel for non-surgical gum treatment
This trial tests a gel called Pocket-X used during non-surgical gum therapy for serious gum disease (periodontitis). It aims to see if the gel helps improve gum health in people with or without well-controlled type 2 diabetes.
Verona, ItalyAges 18–80 - NCT07377344Recruiting
Gum health care during pregnancy
This trial tests ways to improve gum health during pregnancy. If you have gum disease or are at risk, the study may provide dental care that could help both you and your baby.
San Francisco, CaliforniaAges 18 years+ - NCT07349056Recruiting
Early effects of jaw surgery on gum health
This trial looks at how jaw surgery affects your gums and supporting tissues over six months. It may help if you have certain jaw misalignments need surgery.
EdirneAges 18–65 - NCT07343804Recruiting
Dental root canal and heart disease risk study
This trial tests whether treating a tooth infection with a root canal can lower blood markers linked to heart risk in people with stable heart disease.
Rohtak, HaryanaAges 30 years+ - NCT07327060Recruiting
Camera-Assisted Parent Training for Children's Teeth
This study tests whether teaching parents with a small intraoral camera can help improve their child's toothbrushing habits. It focuses on children ages 5–7 who have a new permanent molar coming in.
AydinAges 5–7 - NCT07310212Recruiting
Comparing two root canal techniques for pain and success
This study compares two methods of filling a root canal after cleaning it: a traditional lateral condensation technique and a newer warm vertical obturation technique. The goal is to see which one causes less pain afterward and has a better success rate.
Amman, Amman GovernateAges 18 years+ - NCT07297836Recruiting
Dentist practices for treating baby teeth in France
This study surveys dentists in France about how they treat non-vital (nerve-damaged) baby teeth. It aims to understand current professional practices.
StrasbourgAges 18 years+ - NCT07306026Recruiting
Testing a toothbrush's bristles on plaque and gums
This trial compares how well different toothbrush bristles remove plaque and affect gum health. It may help find the best toothbrush design for everyday oral care.
Buffalo, New YorkAges 18–70 - NCT07296965Recruiting
Oral bacteria in carotid artery plaque study
This study looks at the bacteria living in your mouth and whether they are linked to plaque buildup in the carotid artery (the main artery in your neck). If you are already scheduled for surgery to remove that plaque, the researchers will take samples from your mouth and the plaque to compare them.
BudapestAges 18 years+ - NCT07292870Recruiting
Biological treatments for deep gum bone defects
This trial tests whether biological agents can help heal deep gum bone defects that remain after standard non-surgical cleaning. It may be an option for people who still have deep pockets around their teeth and need a minimally invasive surgical procedure.
Leuven, Vlaams BrabantAges 18 years+ - NCT06291350Recruiting
Mouth bacteria in gum disease with blistering condition
This study looks at the bacteria in the mouth and gut of people with a blistering gum condition (mucous membrane pemphigoid) and gum disease. It aims to understand if certain bacteria are linked to the disease, which could lead to better treatments.
NiceAges 18 years+ - NCT07256691Recruiting
Bioceramic vs. resin sealer for root canal pain
This study tests two types of sealing materials used in root canals (a newer bioceramic one vs. a standard resin one) to see which causes less pain after treatment. If you have an infected, pain-free tooth that needs a root canal, this trial may help guide better care.
Lahore, Punjab ProvinceAges 18–55 - NCT07237620Recruiting
Comparing medicines for failed root canal treatment
This trial compares different medicines placed inside the tooth after a failed root canal to help heal the infection at the root tip. If you have a back tooth that still has an infection even though it had a root canal years ago, this study may test which medicine works best for you.
Hatay, AntakyaAges 18–60 - NCT07205172Recruiting
Gum looks and teeth crowding in children
This study looks at how the appearance of the gums relates to crowding of teeth in children. It will examine kids in different stages of tooth development to see if there is a link.
RomaAges 5–16 - NCT07205588Recruiting
Dental health check using digital tools
This study uses digital tools to assess dental problems in adults who are new to a dental practice or haven't visited in the last six months. It aims to understand how well these tools work for finding dental issues.
ChâtillonAges 18 years+ - NCT07198919Enrolling by invitationPhase 1/Phase 2
Pain relief during root canal for infected tooth: gel vs. antibiotic paste
This trial compares two medicines placed inside a tooth after root canal cleaning to see which reduces pain better between appointments. If you have an infected single-root tooth and are between 16-45 years old, you may be able to join.
Karachi, SindhAges 16–45 - NCT07180498Recruiting
Tea tree vs chlorhexidine mouthwash after wisdom tooth removal
This study compares a tea tree oil mouthwash and a standard chlorhexidine mouthwash to see which helps better after wisdom tooth removal. It may help you heal faster and with less discomfort.
SanliurfaAges 18–65 - NCT06252935Recruiting
Collagen membrane for gum and bone repair
This trial tests a new collagen membrane (FormaAid®) for repairing gum and bone damage from gum disease. It may help people with deep gum pockets and bone loss who are not smokers and have well-controlled health conditions.
Taipei, TaiwanAges 18–70 - NCT07107100Recruiting
Comparing two types of retainers after braces
This study compares two types of retainers (a wire that keeps teeth in place) after braces are removed: one that is directly bonded to the teeth and one that is made indirectly. It looks at which type keeps gums healthy, lasts longer, and how likely it is to break.
Karachi, SindhAges 13–40 - NCT07088679Recruiting
Natural gel for dental implant gum disease
This trial tests a natural gel to treat gum disease around dental implants. It may help reduce bleeding and bone loss around implants.
Pavia, LombardyAges 18–70 - NCT07088809Enrolling by invitation
Nanoparticles with Platelet-Rich Fibrin for Gum Recession
This trial tests a new material to treat gum recession—tiny particles mixed with your own blood components (platelet-rich fibrin) placed as a membrane. The goal is to see if it helps cover exposed roots and improve gum health.
Tanta, Gharbia GovernorateAges 20–45 - NCT07059481Recruiting
Root canal sealers and oxidative stress study
This study is looking at how different types of root canal filling materials (sealers) affect oxidative stress markers in the body. It is for people with a single tooth that has a chronic infection at the root tip and needs a root canal.
Ordu, Ordu- AltınorduAges 18–45
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Common questions
- Are there clinical trials for periodontitis?
- Yes. Clin2 currently lists 271 recruiting periodontitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a periodontitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a periodontitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.