Clinical trials
Perioperative clinical trials
Below are recruiting perioperative clinical trials, each written for real people, not researchers. We’re tracking 332 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06923787RecruitingPhase 2
Lidocaine for colon cancer surgery recovery
This trial tests whether giving lidocaine through an IV during and after colon cancer surgery can help with recovery and boost your immune system. It's for people having laparoscopic colon surgery who haven't had chemotherapy before.
LjubljanaAges 18–80 - NCT06923475RecruitingPhase 2/Phase 3
Chemo plus immunotherapy before surgery for bile duct cancer
This trial tests whether giving chemotherapy (gemcitabine and cisplatin) combined with immunotherapy (pembrolizumab) before and after surgery can improve outcomes compared to having surgery right away. It is for people with bile duct cancer that can be removed or is borderline removable.
AmsterdamAges 18 years+ - NCT06897046RecruitingPhase 2
Study of Iparomlimab and Tuvonralimab for resectable lung cancer
This trial tests two immunotherapy drugs (iparomlimab and tuvonralimab) before and after surgery for people with a certain type of lung cancer that can be removed. It aims to see if this treatment helps improve outcomes.
BeijingAges 18 years+ - NCT06889077Enrolling by invitation
QR code learning tool for nursing students
This study tests if QR codes in perioperative education materials help second-year nursing students learn better. You might join if you are a second-year nursing student at Gülhane Nursing Faculty.
AnkaraAges 18 years+ - NCT06885268RecruitingPhase 3
Blood pressure management during non-cardiac surgery
This trial tests whether noradrenaline is better than standard care for preventing dangerously low blood pressure during surgery. If you are having non-cardiac surgery that lasts at least an hour and are expected to stay overnight, this study may be for you.
KatowiceAges 45 years+ - NCT06869213RecruitingPhase 2
Adebrelimab plus chemo before and after surgery for esophageal cancer
This trial tests a combination of the immunotherapy drug adebrelimab (SHR-1316) and chemotherapy given before and after surgery for locally advanced esophageal squamous cell carcinoma that can be removed. The goal is to see if this approach helps shrink the tumor and improves outcomes.
BeijingAges 18–75 - NCT06865040Recruiting
Inhaled treatment before lung cancer surgery to prevent lung complications
This trial tests whether giving an inhaled medication before lung cancer surgery helps prevent breathing problems after the operation. It is for people whose lung function is lower than normal, which puts them at higher risk for complications after surgery.
AmiensAges 18 years+ - NCT06864624RecruitingPhase 2
Perioperative sunvozertinib for stage II-IIIB NSCLC with EGFR exon 20 insertion
This trial tests the drug sunvozertinib before and after surgery for non-small cell lung cancer that has a specific EGFR mutation (exon 20 insertion). It aims to see if the drug can help shrink tumors and improve outcomes for patients whose cancer is at stage II, IIIA, or IIIB.
Changsha, HunanAges 18 years+ - NCT06864819Recruiting
Alcohol blood test and surgery recovery study
This study looks at a blood test called phosphatidylethanol (PEth) to see if it can help predict how well you recover after surgery. It is for people who drink alcohol regularly and are having elective surgery with a longer hospital stay or ICU stay at University Hospitals Cleveland Medical Center.
Cleveland, OhioAges 21–79 - NCT06849466Enrolling by invitationPhase 4
Perioperative dexmedetomidine for chronic pain after lung surgery
This study tests whether giving the medication dexmedetomidine during and after surgery can prevent long-term pain after a thoracoscopic lung resection. If you are scheduled for this type of lung surgery, you may be able to join and help see if this drug makes recovery less painful over time.
Beijing, Beijing MunicipalityAges 18–80 - NCT06839144RecruitingPhase 2
Medications before surgery to slow ovarian cancer growth
This trial tests whether giving two common medications before and after surgery can slow the growth of ovarian cancer. The medications may help reduce stress signals that could make cancer spread faster during surgery.
Ramat GanAges 20–85 - NCT06824935Enrolling by invitation
Cataract surgery anesthesia needs study
This study looks at how much anesthesia is needed during outpatient cataract surgery. It may help find the right approach for your comfort and safety.
IstanbulAges 18 years+ - NCT06808971RecruitingPhase 2
Perioperative drug combo for advanced stomach cancer
This study tests a combination of four drugs given before and after surgery for a type of stomach or throat-stomach cancer that can be removed. The drugs are adebrelimab (immunotherapy), nab-paclitaxel, oxaliplatin, and tegafur. The goal is to see if this combination works better than standard treatments.
BeijingAges 18–75 - NCT06807866RecruitingPhase 4
Duloxetine for pain after hip replacement surgery
This trial tests if duloxetine, a medication that helps with nerve pain, can reduce pain after hip replacement surgery. It may help patients who are having a first-time total hip replacement.
Miami, FloridaAges 18 years+ - NCT06793163Recruiting
Finding causes of severe allergic reactions during surgery
This study looks at what causes severe allergic reactions during surgery. It helps doctors find out which medicine or substance triggered the reaction, so they can avoid it in the future.
Beijing, Beijing MunicipalityAges 2 years+ - NCT06031285RecruitingPhase 2
Perioperative immunotherapy plus TACE-HAIC for liver cancer with portal vein tumor thrombus
This trial tests a combination of immunotherapy (sintilimab), a targeted anti-angiogenic drug (bevacizumab biosimilar), and liver-directed therapies (TACE-HAIC) before and after surgery for hepatocellular carcinoma that has spread to the portal vein. The goal is to see if this approach improves outcomes for patients with advanced but resectable liver cancer.
Guangzhou, GuangdongAges 18–75 - NCT06776640Recruiting
Vitamin D3 before dental implant surgery for better bone bonding
This trial tests whether taking vitamin D3 pills before and after dental implant surgery helps the implant bond better with the bone. It is for people who have low vitamin D levels and are already scheduled for an implant.
Nantes, NantesAges 18 years+ - NCT06770179Enrolling by invitation
Lung breathing maneuver for kids during surgery
This study tests a special breathing maneuver (ultrasound-guided lung recruitment) during surgery to see if it helps prevent small areas of lung collapse in children. It may help kids with longer surgeries keep their lungs open and working better afterward.
IstanbulAges 1–14 - NCT06030804Recruiting
Dexmedetomidine during surgery and long-term survival
This trial studies whether adding a medication called dexmedetomidine during cancer surgery can improve long-term survival. It is for older adults having major cancer surgery that lasts at least two hours and who will need a pain pump after the operation.
Hefei, AnhuiAges 60 years+ - NCT06731998Recruiting
Improving pain control after cancer surgery
This study compares different methods of managing pain after minimally invasive surgery for abdominal cancers. It aims to find which approach works best to reduce pain and improve recovery.
Pittsburgh, PennsylvaniaAges 18–89 - NCT06732193Recruiting
Fissios App for recovery after lung cancer surgery
This trial tests whether using a smartphone app (Fissios) after lung cancer surgery helps you recover with fewer complications. If you are scheduled for lung surgery for non-small cell lung cancer and have a smartphone, you may be eligible.
Madrid, MadridAges 18 years+ - NCT05738603Recruiting
Predicting low blood pressure during head and neck flap surgery
This study looks at a way to predict low blood pressure during head and neck free flap surgery (when tissue is moved from one place to another). If successful, it may help the surgical team prevent complications by preparing earlier.
Poznan, PoznańAges 18 years+ - NCT06715709Enrolling by invitationPhase 4
How many doses of dexamethasone before knee replacement?
This trial compares different numbers of doses of dexamethasone (a steroid that reduces inflammation) given around the time of knee replacement surgery. It aims to find the best balance of pain control and side effects.
Rochester, MinnesotaAges 18 years+ - NCT06639724RecruitingPhase 1
Test of fostamatinib with chemo before and after surgery for pancreatic cancer
This trial tests adding a new drug, fostamatinib, to standard chemotherapy before and after surgery for pancreatic cancer that can be removed. The goal is to see if the combination helps reduce the chance of cancer coming back.
La Jolla, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for perioperative?
- Yes. Clin2 currently lists 332 recruiting perioperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a perioperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a perioperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.