Clinical trials
Perioperative clinical trials
Below are recruiting perioperative clinical trials, each written for real people, not researchers. We’re tracking 337 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT05120076RecruitingPhase 3
Dexamethasone during surgery to reduce hip surgery pain and nausea
This trial tests whether a single steroid medicine called dexamethasone given around the time of surgery can reduce pain and nausea after a periacetabular osteotomy. It may help you feel more comfortable in the first days after surgery, depending on your medical history.
ZurichAges 18–99 - NCT05182944RecruitingPhase 2
Perioperative immunotherapy plus chemotherapy for resectable throat cancer
This trial studies whether adding camrelizumab (an immune system drug) to chemotherapy before and around surgery can improve outcomes for people with resectable esophageal squamous cell carcinoma (ESCC). If you are eligible, treatment is given around the time of planned surgery to remove the tumor and lymph nodes.
Zhengzhou, HenanAges 18–80 - NCT05185739RecruitingPhase 2
Pembrolizumab and lenvatinib before liver surgery for resectable cancer
This trial tests whether giving pembrolizumab (an immune therapy) and lenvatinib (a targeted pill) before planned liver surgery can improve outcomes for people with certain types of operable hepatocellular carcinoma (HCC). It’s meant for tumors that can be removed with curative intent, but still carry a risk of coming back.
BirminghamAges 18 years+ - NCT05199025Recruiting
Study of blood and lab markers around major surgeries
This study checks blood and other lab “biomarkers” during the time before and after major surgeries to see if they can help guide perioperative care. You might be eligible if you are having certain planned heart, lung, GI, or blood-vessel surgeries and can give informed consent.
Breda, North BrabantAges 18 years+ - NCT05264896RecruitingPhase 3
Stomach cancer surgery plus two chemo plans
This trial compares two chemotherapy schedules around stomach cancer surgery: giving chemo before and after surgery (FLOT) versus giving chemo after surgery (XELOX). It’s meant to see which plan works better and is easier to tolerate for locally advanced disease that has not spread.
Hong KongAges 18 years+ - NCT05292235Recruiting
Study of surgery outcomes for prostate enlargement
This study looks at how well surgery works for an enlarged prostate (“benign prostatic hyperplasia”) and which care factors affect results. It may help improve future treatment planning and outcomes for people in Hong Kong.
Hong KongAges 18 years+ - NCT05353348Recruiting
Program to treat mild anemia around heart surgery
This trial tests a combined treatment plan to improve anemia (low blood count/iron levels) before and around the time of major elective heart surgery. It may help reduce the need for blood transfusions and support safer recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT05606848Recruiting
Testing a special nutrition drink around surgery for gut cancer
This study tests whether a special medical nutrition (a drink/food meant for people who need medical nutrition) given around the time of surgery helps patients with gastrointestinal cancer recover better. It aims to see if this nutrition approach is safe and beneficial when cancer is being removed.
BeijingAges 18–75 - NCT05613478RecruitingPhase 3
Immunotherapy plus targeted medicine with TACE around liver surgery
This Phase 3 trial tests whether combining camrelizumab and apatinib with TACE before/around liver cancer surgery can improve outcomes for people with certain stages of hepatocellular carcinoma (HCC). It may help by strengthening the immune attack on cancer and by blocking blood supply to tumors.
Nanjing, JiangsuAges 18 years+ - NCT05679661Recruiting
Immunity-focused nutrition before surgery to reduce lung infections
This study gives an immunity-supporting nutrition plan and an oral cleaning product before and around surgery to help older adults avoid breathing-related complications. It is mainly for people at higher risk of post-surgery lung problems, and it checks whether the approach is safe and helpful.
BeijingAges 65 years+ - NCT05693363Recruiting
Scan lung tissue with a PET-CT during thoracic surgery
This study tests whether a special imaging scan using a radioactive sugar (18F-FDG) can help doctors better examine lung cancer tissue during thoracic surgery. You may be offered the scan around the time of your operation to help researchers learn how well it works.
GhentAges 18 years+ - NCT05738603Recruiting
Predicting low blood pressure during head and neck flap surgery
This study looks at a way to predict low blood pressure during head and neck free flap surgery (when tissue is moved from one place to another). If successful, it may help the surgical team prevent complications by preparing earlier.
Poznan, PoznańAges 18 years+ - NCT05739045RecruitingPhase 2
Nivolumab plus SOX before and around stomach cancer surgery
This Phase 2 trial tests whether adding nivolumab to standard chemotherapy (SOX) given before and around surgery can improve outcomes for people with certain stomach or stomach–esophagus junction cancers. It aims to shrink or control the cancer and make surgery more effective.
Hangzhou, ZhejiangAges 18–80 - NCT05755230Recruiting
Study of health results around surgery
This study follows people who are having surgery to see what happens before, during, and after the procedure. It may help doctors understand what factors are linked to better recovery.
Buenos AiresAges Any age - NCT05760339Recruiting
Intermittent fasting vs carbohydrate drinks before elective surgery
This study compares two ways of eating before planned (elective) orthopedic surgery: intermittent fasting versus carbohydrate drinks. It aims to see which approach is safer and works better around the time of surgery.
Amsterdam, North HollandAges 18 years+ - NCT05818332Recruiting
ClassIntra® tool to improve outcomes during surgery
This trial tests whether using an in-the-operating-room learning/documentation tool (ClassIntra®) can improve care and outcomes for patients during surgery. You may be invited if you’re having certain inpatient operations with anesthesia involvement.
NijmegenAges 18–110 - NCT05855200RecruitingPhase 3
Dostarlimab around surgery for certain untreated colon cancers
This trial studies dostarlimab given around the time of colon cancer surgery for people with untreated, resectable (operable) stage T4N0 or stage III colon cancer that has specific tumor markers. It may help shrink or eliminate the cancer before or after surgery by boosting the immune response.
Tucson, ArizonaAges 18 years+ - NCT05865743RecruitingPhase 3
Antibiotic cloth before surgery to prevent esophagus infection
This Phase 3 trial tests whether using an antibiotic decolonization treatment around the time of esophagus surgery can reduce serious infections afterward. It may help you lower the risk of postoperative infectious complications after curative esophagectomy or esophagus reconstruction.
LeuvenAges 18 years+ - NCT05893342Recruiting
Checking frailty during surgery in older adults
This study looks at “frailty,” or how well the body may handle stress, around the time of surgery in people age 65 and older. It may help doctors better understand who is at higher risk and how to plan care around surgery.
Las Palmas de Gran Canaria, Las PalmasAges 65 years+ - NCT05894668Recruiting
Study outcomes of a combined kidney stone surgery approach in Asia
This study looks at how well a specific kidney-stone operation (ECIRS) works and what factors during surgery relate to outcomes. You may be able to join if you have urinary (kidney) stones and are planning to have ECIRS, with complete surgical records.
Hong KongAges 18 years+ - NCT05899465RecruitingPhase 3
Tranexamic acid during melanoma surgery to reduce bleeding
This Phase 3 trial tests whether giving tranexamic acid (a medicine that helps reduce bleeding) around the time of surgery can improve outcomes for people with invasive skin melanoma. It may help reduce surgical bleeding while keeping patients safe.
Aarhus, Central JutlandAges 18–80 - NCT05906030Recruiting
Ultrasound to study diaphragm function around surgery
This trial uses ultrasound (a non-painful scanning method) to measure how well the diaphragm works around the time of surgery. It aims to learn whether diaphragm changes during surgery relate to breathing problems, especially in people undergoing abdominal, pelvic, or vascular operations.
Stockholm, Stockholm CountyAges 18–100 - NCT05912257Recruiting
Nutrition program before and after surgery to protect function
This study tests whether an “optimizing nutrition” plan before and after cancer surgery can help older adults maintain physical strength and daily functioning. You may be randomly assigned to the nutrition program or another study group, and you’ll be asked about diet and physical function.
Durham, North CarolinaAges 55 years+
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Common questions
- Are there clinical trials for perioperative?
- Yes. Clin2 currently lists 337 recruiting perioperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a perioperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a perioperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.