Clinical trials
Peripheral Neuropathy clinical trials
Below are recruiting peripheral neuropathy clinical trials, each written for real people, not researchers. We’re tracking 162 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06763575Recruiting
Surgical glove compression to prevent nerve damage from paclitaxel
This trial tests if wearing surgical gloves that compress the hands can prevent nerve damage caused by the chemotherapy drug paclitaxel. If you have a solid tumor and are getting paclitaxel every 3 weeks, this might help reduce numbness, tingling, or pain in your hands.
Bangkok, BangkokAges 18 years+ - NCT05786599RecruitingPhase 2/Phase 3
Low-dose methadone for chemotherapy nerve pain
This trial studies whether methadone can reduce painful nerve damage caused by certain chemotherapy drugs. It is for adults who have ongoing nerve pain for months after chemotherapy ended and may help by lowering neuropathic (nerve) pain.
Nanaimo, British ColumbiaAges 19 years+ - NCT07177820Recruiting
Virtual group acupuncture for chemo-related nerve pain
This study tests if virtual group acupuncture can help reduce nerve pain and numbness caused by chemotherapy (called CIPN). It is for people who finished taxane-based chemo for early-stage breast cancer and still have symptoms.
Charlestown, MassachusettsAges 18–80 - NCT07016971RecruitingPhase 1
CBG/CBD oil for nerve pain from chemotherapy
This trial tests whether a blend of CBG and CBD oils can help relieve nerve pain, tingling, or weakness caused by platinum-based chemotherapy in people with certain gastrointestinal cancers. If you have had colorectal, biliary, pancreatic, esophageal, gastric, or small intestinal cancer and completed chemo in the last 2 years, you may be able to join.
Hershey, PennsylvaniaAges 21 years+ - NCT06430814Recruiting
Blood test to predict nerve damage from paclitaxel
This study looks at whether certain markers in your blood can predict nerve damage from paclitaxel chemotherapy. If you join, researchers will monitor your nerve health during treatment to better understand and possibly prevent side effects.
OdenseAges 18 years+ - NCT06389721Recruiting
Preventing nerve damage from breast cancer chemotherapy
This study looks at how certain chemotherapy drugs affect the brain and cause nerve damage (peripheral neuropathy) in people with breast cancer. The goal is to find ways to prevent or reduce these side effects so that treatment can be more comfortable and effective.
Houston, TexasAges 18 years+ - NCT05840562RecruitingPhase 3
Capsaicin skin patch vs duloxetine for nerve pain after chemo
This Phase 3 trial tests whether a capsaicin patch works better than duloxetine tablets to reduce painful nerve pain after chemotherapy. It aims to help people whose “gloves and socks” nerve pain has lasted after chemo.
AngersAges 18 years+ - NCT05411523Recruiting
Spinal cord stimulation study for long-term chemotherapy nerve pain
This trial tests whether spinal cord stimulation can reduce pain and improve quality of life in people with long-lasting nerve pain from chemotherapy (CIPN). You must already have tried at least two nerve-pain medicines and still have significant pain, and you must have had a successful spinal cord stimulator test before joining.
Rochester, MinnesotaAges 18 years+ - NCT04970121RecruitingPhase 2
Duloxetine for chemotherapy nerve pain in solid tumor patients
This Phase 2 trial tests duloxetine to see if it safely reduces painful nerve damage caused by chemotherapy (especially taxanes) in people with solid tumors. If you have moderate-to-severe nerve pain and meet lab and heart-safety checks, this study may be an option.
Bengbu, AnhuiAges 18–75 - NCT04763356Recruiting
Remote monitoring to manage nerve pain after chemotherapy
This study tests whether remote check-ins (via phone/app/website) can help manage chemotherapy-related nerve pain in the hands and feet. It enrolls adults who developed nerve symptoms after certain cancer medicines and need ongoing monitoring.
Salt Lake City, UtahAges 18 years+ - NCT06483620Recruiting
Arabic quality of life questionnaire for diabetic neuropathy
This trial tests a new Arabic questionnaire to measure quality of life for people with diabetic neuropathy. It helps doctors understand how nerve pain affects daily life.
Cairo, Giza GovernorateAges 18–70 - NCT07714278Enrolling by invitation
Video-based rehab for chemotherapy nerve damage
This study tests a personalized rehab program using video analysis to help people with chemotherapy-induced nerve damage (numbness, tingling, weakness) improve their walking and daily life.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07554443Recruiting
Wearable Device to Improve Balance and Walking in Older Adults
This study tests a wearable device called Walkasins that uses gentle vibrations on your foot to help improve balance and walking ability. It's designed for older adults with nerve damage in their feet who have difficulty with balance.
Jacksonville, FloridaAges 60 years+ - NCT07481149RecruitingPhase 3
Virtual exercise program for chemo nerve damage
This study tests a virtual exercise program to help people with nerve pain or numbness after chemotherapy. It is designed for anyone who finished chemo at least 6 months ago and still has symptoms in their hands or feet.
Toronto, OntarioAges 18 years+ - NCT06914557RecruitingPhase 2
Scrambler therapy plus duloxetine for chemo nerve pain
This study tests whether adding a non-invasive device called Scrambler Therapy to the usual nerve pain medicine (duloxetine) can better relieve chemotherapy-induced nerve pain. It is for people with cancer who still have significant nerve pain despite taking duloxetine.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07009717Recruiting
Big toe strength and chemo nerve damage
This study looks at whether the strength of your big toe is related to nerve damage from chemotherapy. It involves a one-time test of your toe strength and some questionnaires. It may help researchers better understand how chemo affects your nerves.
Gainesville, FloridaAges 18–90 - NCT07625020Recruiting
Nerve Hydrodissection for Diabetic Nerve Entrapment Pain
This trial tests a minimally invasive ultrasound-guided procedure that uses fluid injection to free trapped nerves in the lower legs of people with diabetes. The goal is to relieve pain, numbness, and weakness when standard medications haven't worked well enough.
Chongqing, Chongqing MunicipalityAges 18–85 - NCT07700901Recruiting
Acupuncture and exercise for nerve pain from chemo
This study tests if electroacupuncture (a type of acupuncture with mild electric pulses) combined with exercise can help reduce numbness, tingling, or pain caused by certain chemotherapy drugs. If you have nerve symptoms from taxane or platinum chemo and can walk on your own, this may be a good fit.
Changhua, ChanghuaAges 18–80 - NCT05904340Recruiting
Acupuncture-like electrical stimulation for nerve pain after chemo
This trial studies whether a skin-applied, acupuncture-like electrical treatment can reduce ongoing nerve pain (chemotherapy-induced peripheral neuropathy) after breast cancer chemotherapy. It may help if your nerve symptoms have not improved after finishing chemo.
Changhua, ChanghuaAges 18–80 - NCT07285356Recruiting
Surgical gloves to prevent nerve damage from oxaliplatin
This trial tests whether wearing special surgical gloves during oxaliplatin chemotherapy can help prevent nerve damage (numbness or tingling) in people with advanced colon cancer.
São Paulo, São PauloAges 18 years+ - NCT05606068Recruiting
Cooling sleeve to help prevent nerve damage from paclitaxel
This trial tests a limb “cryocompression” system (a cooling and gentle pressure device) to help prevent chemotherapy-related nerve pain and numbness. It’s for people starting weekly paclitaxel, and may help those trying to avoid or reduce peripheral neuropathy.
SingaporeAges 21–80 - NCT04299893RecruitingPhase 2/Phase 3
Ozone treatment for chemotherapy nerve pain
This trial tests whether ozone therapy can reduce painful nerve damage caused by chemotherapy. It is for adults with ongoing moderate-to-severe pain in the hands or feet after chemotherapy.
Las Palmas de Gran Canaria, Las PalmasAges 18–100 - NCT07673614Recruiting
Gentle brain stimulation for nerve pain from chemotherapy
This study tests a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) to see if it can reduce nerve pain, numbness, or tingling caused by chemotherapy. If you've finished cancer treatment but still have these symptoms, this may help improve your quality of life.
Ann Arbor, MichiganAges 18–85 - NCT06737926Recruiting
Balance exercises for chemotherapy nerve damage in breast cancer
This study tests whether special balance and coordination exercises can help reduce nerve damage side effects (like numbness or tingling) caused by chemotherapy in breast cancer patients. You may benefit if you have these symptoms and want to improve your balance and movement.
Lahore, Punjab ProvinceAges 30–65
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Common questions
- Are there clinical trials for peripheral neuropathy?
- Yes. Clin2 currently lists 162 recruiting peripheral neuropathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral neuropathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral neuropathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Chemotherapy-induced Peripheral Neuropathy
- Diabetic Peripheral Neuropathy
- Peripheral Neuropathy Due to Chemotherapy
- Peripheral Neuropathy With Type 2 Diabetes
- Paclitaxel-induced Peripheral Neuropathy
- Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients
- Taxane-induced Peripheral Neuropathy
- Peripheral Arterial Disease
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.