Clinical trials
Peripheral Neuropathy clinical trials
Below are recruiting peripheral neuropathy clinical trials, each written for real people, not researchers. We’re tracking 162 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06945380Recruiting
Mobile app teaching caregivers massage for nerve pain from chemo
This study tests if a mobile app can help caregivers learn massage techniques to ease nerve pain (numbness, tingling, or burning) in patients who have lingering symptoms from chemotherapy. It's for people who finished chemo at least 6 months ago and still have moderate-to-severe symptoms.
Jacksonville, FloridaAges 18 years+ - NCT05763706Recruiting
Laser treatment for nerve pain after chemotherapy
This trial looks at whether light (photobiomodulation) and laser-like therapy can reduce nerve pain in people who developed neuropathy after chemotherapy. If you match the chemotherapy and language requirements, you may be screened to see if this treatment is safe and helpful for your symptoms.
Hasselt, LimburgAges 18 years+ - NCT04763356Recruiting
Remote monitoring to manage nerve pain after chemotherapy
This study tests whether remote check-ins (via phone/app/website) can help manage chemotherapy-related nerve pain in the hands and feet. It enrolls adults who developed nerve symptoms after certain cancer medicines and need ongoing monitoring.
Salt Lake City, UtahAges 18 years+ - NCT05840562RecruitingPhase 3
Capsaicin skin patch vs duloxetine for nerve pain after chemo
This Phase 3 trial tests whether a capsaicin patch works better than duloxetine tablets to reduce painful nerve pain after chemotherapy. It aims to help people whose “gloves and socks” nerve pain has lasted after chemo.
AngersAges 18 years+ - NCT06389721Recruiting
Preventing nerve damage from breast cancer chemotherapy
This study looks at how certain chemotherapy drugs affect the brain and cause nerve damage (peripheral neuropathy) in people with breast cancer. The goal is to find ways to prevent or reduce these side effects so that treatment can be more comfortable and effective.
Houston, TexasAges 18 years+ - NCT04970121RecruitingPhase 2
Duloxetine for chemotherapy nerve pain in solid tumor patients
This Phase 2 trial tests duloxetine to see if it safely reduces painful nerve damage caused by chemotherapy (especially taxanes) in people with solid tumors. If you have moderate-to-severe nerve pain and meet lab and heart-safety checks, this study may be an option.
Bengbu, AnhuiAges 18–75 - NCT06471517Recruiting
Nerve device for diabetic foot numbness
This trial tests a special device that uses mild electrical pulses to help improve problems caused by diabetic nerve damage, such as numbness and pain in the feet. If you have diabetic neuropathy and can walk on your own, this study may be a good option.
BelgradeAges 18 years+ - NCT06763575Recruiting
Surgical glove compression to prevent nerve damage from paclitaxel
This trial tests if wearing surgical gloves that compress the hands can prevent nerve damage caused by the chemotherapy drug paclitaxel. If you have a solid tumor and are getting paclitaxel every 3 weeks, this might help reduce numbness, tingling, or pain in your hands.
Bangkok, BangkokAges 18 years+ - NCT07558447Recruiting
Studying Tiny Particles to Predict Chemotherapy Nerve Damage
This study looks at tiny particles in your blood to understand and potentially predict nerve damage caused by certain chemotherapy drugs. Researchers will monitor you before, during, and after your cancer treatment to see if these particles can help warn doctors about this common side effect.
MilanAges 18 years+ - NCT06483620Recruiting
Arabic quality of life questionnaire for diabetic neuropathy
This trial tests a new Arabic questionnaire to measure quality of life for people with diabetic neuropathy. It helps doctors understand how nerve pain affects daily life.
Cairo, Giza GovernorateAges 18–70 - NCT04658693Recruiting
Restore leg sensation in diabetic nerve damage with safe stimulation
This study tests a treatment that delivers mild stimulation to help bring back lower-limb feeling in people with diabetic nerve damage (or an insensate foot) and may also protect nerves. If you qualify and can safely take part in testing and follow-up, it could improve sensation and walking comfort.
Cleveland, OhioAges 18 years+ - NCT06914557RecruitingPhase 2
Scrambler therapy plus duloxetine for chemo nerve pain
This study tests whether adding a non-invasive device called Scrambler Therapy to the usual nerve pain medicine (duloxetine) can better relieve chemotherapy-induced nerve pain. It is for people with cancer who still have significant nerve pain despite taking duloxetine.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07009717Recruiting
Big toe strength and chemo nerve damage
This study looks at whether the strength of your big toe is related to nerve damage from chemotherapy. It involves a one-time test of your toe strength and some questionnaires. It may help researchers better understand how chemo affects your nerves.
Gainesville, FloridaAges 18–90 - NCT07481149RecruitingPhase 3
Virtual exercise program for chemo nerve damage
This study tests a virtual exercise program to help people with nerve pain or numbness after chemotherapy. It is designed for anyone who finished chemo at least 6 months ago and still has symptoms in their hands or feet.
Toronto, OntarioAges 18 years+ - NCT07554443Recruiting
Wearable Device to Improve Balance and Walking in Older Adults
This study tests a wearable device called Walkasins that uses gentle vibrations on your foot to help improve balance and walking ability. It's designed for older adults with nerve damage in their feet who have difficulty with balance.
Jacksonville, FloridaAges 60 years+ - NCT07625020Recruiting
Nerve Hydrodissection for Diabetic Nerve Entrapment Pain
This trial tests a minimally invasive ultrasound-guided procedure that uses fluid injection to free trapped nerves in the lower legs of people with diabetes. The goal is to relieve pain, numbness, and weakness when standard medications haven't worked well enough.
Chongqing, Chongqing MunicipalityAges 18–85 - NCT05606068Recruiting
Cooling sleeve to help prevent nerve damage from paclitaxel
This trial tests a limb “cryocompression” system (a cooling and gentle pressure device) to help prevent chemotherapy-related nerve pain and numbness. It’s for people starting weekly paclitaxel, and may help those trying to avoid or reduce peripheral neuropathy.
SingaporeAges 21–80 - NCT04299893RecruitingPhase 2/Phase 3
Ozone treatment for chemotherapy nerve pain
This trial tests whether ozone therapy can reduce painful nerve damage caused by chemotherapy. It is for adults with ongoing moderate-to-severe pain in the hands or feet after chemotherapy.
Las Palmas de Gran Canaria, Las PalmasAges 18–100 - NCT05904340Recruiting
Acupuncture-like electrical stimulation for nerve pain after chemo
This trial studies whether a skin-applied, acupuncture-like electrical treatment can reduce ongoing nerve pain (chemotherapy-induced peripheral neuropathy) after breast cancer chemotherapy. It may help if your nerve symptoms have not improved after finishing chemo.
Changhua, ChanghuaAges 18–80 - NCT07285356Recruiting
Surgical gloves to prevent nerve damage from oxaliplatin
This trial tests whether wearing special surgical gloves during oxaliplatin chemotherapy can help prevent nerve damage (numbness or tingling) in people with advanced colon cancer.
São Paulo, São PauloAges 18 years+ - NCT06744816RecruitingEarly Phase 1
Can capsaicin cream ease nerve pain after chemotherapy?
This study tests whether a capsaicin cream (made from chili peppers) can help reduce pain in the legs caused by nerve damage from past chemotherapy. It's for people who still have pain 3 months or more after finishing chemo.
Houston, TexasAges 18 years+ - NCT06737926Recruiting
Balance exercises for chemotherapy nerve damage in breast cancer
This study tests whether special balance and coordination exercises can help reduce nerve damage side effects (like numbness or tingling) caused by chemotherapy in breast cancer patients. You may benefit if you have these symptoms and want to improve your balance and movement.
Lahore, Punjab ProvinceAges 30–65 - NCT07109817RecruitingPhase 2
Desloratadine to prevent nerve damage from taxane chemo in breast cancer
This trial tests if the allergy medicine desloratadine can prevent nerve damage (numbness, tingling, pain) caused by taxane chemotherapy in people with early-stage breast cancer. Taking desloratadine daily during chemo may help protect your nerves.
The Bronx, New YorkAges 18 years+ - NCT07352514Recruiting
Natural supplements and exercise for chemo nerve pain
This study tests if a combination of two natural supplements (PEA and Scutellaria) plus a specific exercise program can help reduce nerve pain caused by chemotherapy. It is for people who have had chemotherapy in the last 6 months and still have moderate to severe nerve pain.
Palermo, ItaliaAges 18 years+
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Common questions
- Are there clinical trials for peripheral neuropathy?
- Yes. Clin2 currently lists 162 recruiting peripheral neuropathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral neuropathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral neuropathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Chemotherapy-induced Peripheral Neuropathy
- Diabetic Peripheral Neuropathy
- Peripheral Neuropathy Due to Chemotherapy
- Peripheral Neuropathy With Type 2 Diabetes
- Paclitaxel-induced Peripheral Neuropathy
- Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients
- Taxane-induced Peripheral Neuropathy
- Peripheral Arterial Disease
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.