Clinical trials · Houston, TX
Phase 2 clinical trials in Houston
We’re tracking 66 recruiting phase 2 studies with a site in or near Houston — including Phase 1/Phase 2, Phase 2 and Phase 2/Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Houston
- NCT06989359RecruitingPhase 2
Study of ADX-038 for complement-related kidney disease
This trial tests an experimental drug called ADX-038 for people with certain types of kidney disease that are driven by the complement system (a part of the immune system). The study aims to see if ADX-038 can help slow down or improve kidney function.
Houston, TexasAges 18 years+ - NCT07502508RecruitingPhase 2
Icovamenib for type 2 diabetes with Ozempic
This trial tests an investigational pill called icovamenib for people with type 2 diabetes who are already on Ozempic but still have high blood sugar. The goal is to see if adding icovamenib helps lower blood sugar more safely.
Houston, TexasAges 18–70 - NCT06369259RecruitingPhase 2
Combination treatment for advanced colorectal cancer that resisted standard therapy
This clinical trial tests a new combination of three drugs for people with advanced colorectal cancer that has not responded to standard anti-EGFR treatments. The goal is to see if this combination can shrink tumors or slow the cancer down.
Houston, TexasAges 18 years+ - NCT05548296RecruitingPhase 2
ACR-368 for high-grade endometrial cancer after prior treatments
This Phase 2 trial studies ACR-368 for people with high-grade endometrial cancer that has spread or grown despite at least one prior treatment. It may help by testing whether this drug can better control the cancer after other therapies have not worked.
Houston, TexasAges 18 years+ - NCT06798896RecruitingPhase 2
SPN-817 for hard-to-control focal seizures
This study tests an investigational drug called SPN-817 to see if it can reduce focal seizures (seizures that start in one area of the brain) in adults whose seizures are not well controlled by current medications.
Houston, TexasAges 18–70 - NCT07029581RecruitingPhase 2
Testing ACP-204 for psychosis in Lewy body dementia
This trial tests a new drug called ACP-204 for people with dementia from Lewy body disease or Parkinson's who also have hallucinations or delusions. The goal is to see if the drug can safely reduce these symptoms without worsening thinking problems.
Houston, TexasAges 55–84 - NCT07501702RecruitingPhase 2
Study of a new drug for generalized myasthenia gravis
This study tests a new medication called povetacicept for people with generalized myasthenia gravis. The goal is to see if it can reduce muscle weakness and improve daily functioning.
Houston, TexasAges 18 years+ - NCT07508995RecruitingPhase 2
New pill combo for untreated chronic lymphocytic leukemia
This trial tests a new pill combination for chronic lymphocytic leukemia (CLL) that has not been treated before. The drugs are designed to attack CLL cells in two different ways to try to improve outcomes.
Houston, TexasAges 18 years+ - NCT07053059RecruitingPhase 2
CAR T-cell therapy to prevent relapse in high-risk B-cell ALL
This trial tests a new CAR T-cell therapy (obecabtagene autoleucel) given as a consolidation treatment after initial remission to prevent relapse in people with high-risk B-cell ALL. It's for patients who have achieved first remission but still have high-risk features in their leukemia.
Houston, TexasAges 18 years+ - NCT06514794RecruitingPhase 2
A study of a new cell therapy for T-cell acute lymphoblastic leukemia and lymphoma
This trial tests an investigational cell therapy that uses donated immune cells to find and destroy cancer cells in patients with T-cell acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma (LBL) that has come back or not responded to treatment. The goal is to see if this therapy can help achieve remission for these patients.
Houston, TexasAges 6 months+ - NCT04613596RecruitingPhase 2/Phase 3
Adagrasib for KRAS G12C lung cancer, alone or with pembrolizumab
This trial studies adagrasib (an anti-cancer drug) either alone or with pembrolizumab (an immunotherapy) in people with advanced lung cancer that has a KRAS G12C mutation. It aims to shrink tumors and improve outcomes, including for people without urgent brain treatment needs.
Houston, TexasAges 18 years+ - NCT06567314RecruitingPhase 2
Study of Ivonescimab for advanced skin or prostate cancer
This study tests a new immunotherapy medicine, ivonescimab, in people with advanced skin cancer or advanced prostate cancer. It looks at how safe and effective the drug is.
Houston, TexasAges 18 years+ - NCT06567743RecruitingPhase 2
Study of a new virus therapy for high-risk bladder cancer
This trial tests a new virus-based medicine, cretostimogene grenadenorepvec, given directly into the bladder for people with high-risk non-muscle-invasive bladder cancer. It may help prevent the cancer from coming back, especially for those who have not had BCG treatment or whose cancer did not respond to BCG.
Houston, TexasAges 18 years+ - NCT04752722RecruitingPhase 1/Phase 2
Gene therapy for bladder cancer that came back after BCG
This study tests a new gene therapy (EG-70) given directly into the bladder for people with a high-risk bladder cancer called NMIBC. It may be an option if BCG treatment stopped working, or if you cannot have or choose not to have bladder removal surgery.
Houston, TexasAges 18 years+ - NCT06658899RecruitingPhase 2
Study of CRD-4730 for CPVT (rare heart rhythm disorder)
This study tests an experimental drug called CRD-4730 for people with CPVT, a rare inherited heart rhythm disorder that can cause dangerous fast heartbeats during exercise or stress. The trial will see if the drug can help control these abnormal heart rhythms better than current treatments.
Houston, TexasAges 18–99 - NCT07215390RecruitingPhase 2
Study of APL-3007 plus Syfovre for geographic atrophy
This trial tests whether a new drug called APL-3007, when added to your current Syfovre treatment, can slow the progression of geographic atrophy (an advanced form of dry age-related macular degeneration). It's for people who have already been on Syfovre for at least 6 months.
Bellaire, TexasAges 60 years+ - NCT06990269RecruitingPhase 2
Study of ADX-038 for geographic atrophy in dry AMD
This trial tests an investigational drug (ADX-038) for people with geographic atrophy, a form of advanced dry age-related macular degeneration. The drug is given as an injection into the eye, and the study checks if it can slow down the growth of GA spots.
Bellaire, TexasAges 60 years+ - NCT07115329RecruitingPhase 2
Testing Zelquistinel for major depression
This study tests a new oral medication called Zelquistinel (taken as a tablet) against a placebo for treating major depressive disorder. Researchers want to see if it can reduce depression symptoms, especially when other antidepressants haven't been tried or haven't worked.
Atascocita, TexasAges 18–64
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Where these studies are running near Houston
Institutions with a site for the recruiting phase 2 studies listed above.
- The University of Texas MD Anderson Cancer Center · 6 studies
- ADARx Clinical Site · 2 studies
- Cardurion Investigative Site
- Elevate Synapsis, LLC
- Horizon Clinical Research Group
- Houston Methodist Hospital
- Houston Methodist Hospital - Department of Urology
- Houston Metro Urology
What taking part in a phase 2 study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting phase 2 studies in Texas.
Common questions
- Are there phase 2 clinical trials near Houston?
- Yes. We're currently tracking 66 recruiting phase 2 studies with a site near Houston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a phase 2 study near Houston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Houston to take part?
- Not necessarily. These studies have a site near Houston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a phase 2 trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New phase 2 studies open near Houston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.