Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,904 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06989866Enrolling by invitationPhase 3
Testing if numbing injections reduce pain pill use after nose surgery
This trial tests whether a numbing injection (regional anesthesia) during nose surgery can reduce the need for strong pain pills afterward. It's for people having their first nose surgery at specific military hospitals.
Portsmouth, VirginiaAges 18 years+ - NCT06989177Recruiting
Can a probiotic help with body weight?
This trial tests whether taking a probiotic (a good bacteria supplement) can help with body weight. It is for healthy adults, and also for overweight or obese people who have certain weight-related health issues.
Hangzhou, ZhejiangAges 20–50 - NCT06984744Recruiting
Gum health study testing a new compound
This study tests a compound in gum to see how well it prevents plaque buildup over 4 days. You may be able to join if you are a healthy adult with at least 20 natural teeth and some existing plaque.
Indianapolis, IndianaAges 18–65 - NCT06989840RecruitingPhase 1
Safety study of TVB-3567 for acne
This early-stage study tests a new drug called TVB-3567, which may help treat acne. It checks the drug's safety and how the body processes it, first in healthy people and then in people with moderate to severe acne.
Tempe, ArizonaAges 18–55 - NCT06993155RecruitingPhase 2
Leflutrozole for low testosterone and low sperm count
This trial tests a new drug called Leflutrozole to see if it can improve testicular function in men with low testosterone and low sperm count. The goal is to help increase natural hormone levels and sperm production.
North Hollywood, CaliforniaAges 18–49 - NCT06991257RecruitingPhase 2
Study of PF-07328948 for adults with heart failure
This trial tests a new medicine, PF-07328948, for adults with heart failure to see if it can improve symptoms and daily life. It is for people who have had heart failure for at least 3 months and can walk without too much difficulty.
Beverly Hills, CaliforniaAges 18–79 - NCT06989437RecruitingPhase 2/Phase 3
Study of Ponsegromab for Pancreatic Cancer with Weight Loss
This study tests an experimental drug called ponsegromab for people with advanced pancreatic cancer who experience severe weight loss and fatigue. It aims to see if the drug can help improve weight and energy levels while you continue standard chemotherapy.
Birmingham, AlabamaAges 18 years+ - NCT06990269RecruitingPhase 2
Study of ADX-038 for geographic atrophy in dry AMD
This trial tests an investigational drug (ADX-038) for people with geographic atrophy, a form of advanced dry age-related macular degeneration. The drug is given as an injection into the eye, and the study checks if it can slow down the growth of GA spots.
Gilbert, ArizonaAges 60 years+ - NCT04934228RecruitingPhase 1
Study targeting inflammation in people with obesity and high blood pressure
This Phase 1 study looks at a treatment aimed at reducing “inflammation patterns” that are common in obesity and insulin resistance. If you meet specific health and lab criteria, you may be asked to visit a research lab and provide blood samples to see how the treatment affects your body.
Kansas City, KansasAges 18–79 - NCT06987084Enrolling by invitationEarly Phase 1
Bryophyllum Tea for Kidney Stone Prevention
This study tests whether a special tea made from the Bryophyllum pinnatum plant can help people who get calcium kidney stones. If you've had a stone or high calcium in your urine, this trial may offer a natural option to try.
Montreal, QuebecAges 18–70 - NCT06986993RecruitingPhase 4
Semaglutide for smoking and weight in people with obesity
This study tests whether the medication semaglutide (similar to Ozempic/Wegovy) can help people who smoke and have obesity cut down on cigarettes, even if they aren't ready to quit. Participants will receive the drug and be monitored for changes in smoking habits and health.
Oklahoma City, OklahomaAges 18–65 - NCT06985524Enrolling by invitation
Chinese medicine formula for stomach fullness and discomfort
This trial tests a traditional Chinese medicine formula (Weipi Formula) for people with a feeling of fullness or discomfort in the upper stomach after eating, known as epigastric stuffiness or functional dyspepsia. It aims to see if the herbal mix can improve symptoms.
Nanchang, JiangxiAges 18–80 - NCT06987305RecruitingPhase 3
Clot-busting medication before clot removal for late-arriving stroke
This trial tests whether adding a clot-busting medication (rhTNK-tPA) before a clot-removal procedure (thrombectomy) can improve outcomes for people who have a moderate-to-severe stroke and arrive at the hospital 4.5 to 24 hours after symptoms start. It's for those with a large artery blockage but still enough brain tissue that can be saved.
Wuhan, HubeiAges 18 years+ - NCT06990711RecruitingPhase 1
Siltuximab for antibody-mediated rejection after lung transplant
This trial tests a drug called siltuximab to see if it can help treat a type of lung rejection called antibody-mediated rejection (AMR) in people who have had a lung transplant. You may be eligible if you are currently hospitalized for AMR and are already planning to receive standard treatments.
St Louis, MissouriAges 18 years+ - NCT06991712RecruitingPhase 2
NAD supplements for nerve health in glaucoma
This trial tests whether NAD precursor supplements can improve nerve health and vision in people with glaucoma. If you have glaucoma with mild to moderate vision loss, this study may help understand if these supplements could protect your optic nerve.
Wong Chuk HangAges 18 years+ - NCT06992440RecruitingPhase 2
Empagliflozin for better right heart function in pulmonary hypertension
This trial tests if a diabetes drug can help people with pulmonary arterial hypertension whose right heart function is reduced. Participants take empagliflozin or a placebo for 24 weeks to see if heart function improves.
Baltimore, MarylandAges 18 years+ - NCT04366518RecruitingEarly Phase 1
Personalized brain-based treatment for frequent voice hallucinations
This early-phase study tests a personalized treatment plan for people who hear voices (auditory verbal hallucinations) at least weekly. It uses brain/machine-based information to try to better target hallucinations and monitor safety.
New Haven, ConnecticutAges 18–65 - NCT06653725RecruitingPhase 2
Ketone supplement study for hospitalized heart failure patients
This trial tests if a ketone supplement can help people hospitalized for acute heart failure. The supplement is given orally and aims to support the heart and energy levels during recovery.
AalborgAges 18 years+ - NCT06959004Recruiting
Does substance P trigger migraine attacks without aura?
This study tests whether a substance called substance P can cause migraine attacks in people who have migraine without aura. Results may help understand new ways to prevent or treat migraine.
Glostrup MunicipalityAges 18–65 - NCT05651347RecruitingPhase 3
Melatonin in pregnancy to protect babies with slow growth
This trial studies whether taking melatonin during pregnancy can help protect the baby’s brain and organs in cases of poor fetal growth. It focuses on pregnancies at a specific gestational age with signs that the placenta may not be working well.
Camperdown, New South WalesAges 18 years+ - NCT05816798RecruitingPhase 2/Phase 3
Laser treatment to reduce chronic knee pain before weight-surgery
This trial tests whether photobiomodulation (a type of laser/light therapy) can reduce chronic pain in both knees for people preparing for bariatric (weight-loss) surgery. If you have knee pain that limits daily life, the treatment may help you feel better while you’re in the pre-surgery rehabilitation period.
Goiânia, GoiásAges 18–70 - NCT06975618RecruitingPhase 1/Phase 2
Study of CYH33 for PIK3CA-related overgrowth and vascular malformations
This trial tests a new drug called CYH33 for people with conditions caused by a specific gene mutation (PIK3CA) that leads to abnormal tissue growth or blood vessel problems. It aims to see if the drug is safe and can help shrink or control these growths.
Beijing, Beijing MunicipalityAges Any age - NCT06982508RecruitingPhase 2
Study of obicetrapib on antioxidants in healthy adults
This trial tests whether a new cholesterol-lowering drug, obicetrapib, affects antioxidant levels in the blood and HDL (good cholesterol) particles. It is currently for healthy volunteers only.
Miami Gardens, FloridaAges 18–75 - NCT06979362RecruitingPhase 2
Testing a new medicine for heart failure with thickened heart muscle
This study tests an experimental medicine, CDR132L, to see if it can improve heart structure and function in people with a type of heart failure where the heart muscle is thickened. If you have heart failure with normal pumping function and thickened heart walls, this trial may offer access to a new potential treatment.
Birmingham, AlabamaAges 40–84
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,904 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.