Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,902 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06128278RecruitingPhase 2
Equol supplement and blood vessel health in women
This study tests whether taking an Equol supplement (a soy-related compound) improves blood vessel function in postmenopausal women with and without chronic kidney disease (CKD). It could help women with or without early-stage CKD learn if this supplement supports heart health.
Aurora, ColoradoAges 50–69 - NCT06233461RecruitingPhase 2
A study of TAK-279 for Crohn's disease
This study tests an oral medication called TAK-279 to see if it can safely reduce inflammation in the bowel for people with moderate to severe Crohn's disease who haven't had success with other treatments.
Murrieta, CaliforniaAges 18–75 - NCT06238700Recruiting
Studying allopregnanolone for depression in midlife women
This trial tests whether allopregnanolone, a natural brain chemical, can help depression in women going through menopause. It compares the effects against a placebo to see if it improves mood symptoms.
Boston, MassachusettsAges 40–60 - NCT06229483RecruitingPhase 3
Does tranexamic acid reduce bleeding during brain tumor surgery?
This study tests whether a medication called tranexamic acid (TXA) given during brain tumor surgery can reduce bleeding. If you are having a standard craniotomy for a tumor and don’t have certain health risks, you may be eligible.
Halifax, Nova ScotiaAges 18–80 - NCT06234501Recruiting
Does vitamin B6 help sensory issues in autism?
This trial tests whether taking a daily 100 mg vitamin B6 supplement can help with sensory reactivity in autistic adults. It involves taking either the vitamin or a placebo (fake pill) for a set period and reporting how your senses (like touch, sound, or light) feel.
ReadingAges 18–60 - NCT06230861Recruiting
Quercetin supplement for heart and metabolic health
This study tests whether taking a supplement called quercetin (a natural plant compound) improves heart and metabolic health markers in healthy adults. You'd take the supplement for a period of time, and researchers will measure things like blood sugar and cholesterol.
Preston, LancashireAges 18–65 - NCT06245109RecruitingPhase 4
Pain medicine study for knee osteoarthritis
This study tests how well different pain medicines work for knee osteoarthritis and looks at brain patterns to understand why some people get more relief. It may help you find a treatment that works best for you.
Chicago, IllinoisAges 41 years+ - NCT06248671RecruitingPhase 2
Atorvastatin for preventing migraine attacks
This trial tests whether a daily dose of atorvastatin (a common cholesterol medicine) can prevent migraine attacks in people with episodic migraine. You would keep a headache diary and be randomly assigned to take atorvastatin or a placebo for about 3 months.
BergenAges 18–65 - NCT06246396RecruitingPhase 4
Minocycline for resistant high blood pressure
This study tests whether minocycline, a common antibiotic, can help lower blood pressure in people whose high blood pressure is not controlled by multiple medications. If you have resistant hypertension, this trial may offer a new option to better manage your condition.
Gainesville, FloridaAges 18–100 - NCT06229678RecruitingEarly Phase 1
Ketones and diabetes drug for heart failure with weak pump
This clinical trial looks at whether adding a special diet supplement (ketones) to an SGLT2 inhibitor diabetes drug improves heart function and symptoms in people who have both type 2 diabetes and heart failure with a weakened heart muscle.
San Antonio, TexasAges 18–70 - NCT06206707Recruiting
FMT for Diarrhea and Colitis After Immunotherapy
This trial tests whether a treatment called fecal microbiota transplant (FMT) — transferring healthy gut bacteria — can help relieve diarrhea and colitis caused by immunotherapy drugs. If you have melanoma or kidney cancer and are experiencing diarrhea after immunotherapy, this study may offer a new option.
Aarhus NAges 18 years+ - NCT06209359RecruitingPhase 1
Testing a second diuretic for heart failure patients
This trial tests whether adding a second type of diuretic (water pill) can help people with heart failure who don't respond well to their current diuretic. It aims to find better ways to manage fluid buildup.
New Haven, ConnecticutAges 18 years+ - NCT06218056RecruitingPhase 2
CBD for reducing cigarette smoking in a treatment center
This study tests whether a daily dose of cannabidiol (CBD) can help people who smoke at least 5 cigarettes a day cut down or quit. It is for people staying at a treatment center in Los Angeles where cannabis use is not allowed.
North Hollywood, CaliforniaAges 18–65 - NCT06224530Recruiting
Testing levetiracetam's effect on brain function in psychosis risk
This trial tests whether a single dose of levetiracetam, a medication that affects brain chemistry, can change brain function and thinking in people at risk for psychosis. The goal is to see if it might help prevent symptoms from worsening.
London, LondonAges 18–40 - NCT06213649RecruitingPhase 3
Ulcer treatment trial for active eye infection
This trial tests a new treatment for people who still have eye inflammation after 1 month of standard treatment for a parasitic eye infection (acanthamoeba keratitis). It aims to find a better way to control the infection and reduce inflammation.
Irvine, CaliforniaAges 8 years+ - NCT06225817Recruiting
Can a placebo help with chronic jaw pain and sleep?
This study is testing whether a placebo (a pill with no medication) can help improve sleep and reduce pain for people with long-term jaw or face pain. Researchers want to see if just expecting relief can change how your body handles pain.
Baltimore, MarylandAges 18–88 - NCT06210854RecruitingPhase 2
HPV16/18 Vaccine Trial for Cervical Lesions
This trial tests a new vaccine (pBI-11) given with a device that uses mild electric pulses to help the vaccine enter cells. It is for people who have HPV16 or 18 but no high-grade cervical changes.
Birmingham, AlabamaAges 18 years+ - NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Stanford, CaliforniaAges 18–75 - NCT06227910RecruitingPhase 3
Study of vedolizumab with or without upadacitinib for Crohn's disease
This trial tests combining two medicines, vedolizumab and upadacitinib, to see if they work better together than vedolizumab alone for people with moderate to severe Crohn's disease that hasn't responded well to other treatments.
La Jolla, CaliforniaAges 18–65 - NCT06226805RecruitingPhase 2
Study of BB-031 for acute ischemic stroke
This trial tests a new drug called BB-031 for people who have had a stroke caused by a blocked blood vessel in the brain. The drug may help restore blood flow and reduce damage if given within 24 hours of symptoms starting.
Scottsdale, ArizonaAges 18 years+ - NCT06226883RecruitingPhase 2
Testing MORF-057 for moderate to severe Crohn's disease
This study tests an oral medicine called MORF-057 for people with moderate to severe Crohn's disease. It aims to see if the drug can reduce inflammation and improve symptoms for those who haven't had success with other treatments.
Lancaster, CaliforniaAges 18–85 - NCT06205121RecruitingPhase 2
Testing a new drug for active lung sarcoidosis
This study tests a new medication, OATD-01, for people with active sarcoidosis in their lungs. It aims to see how safe and effective the drug is and if it can improve symptoms.
Birmingham, AlabamaAges 18 years+ - NCT06182397Recruiting
Drug-coated balloon for leg artery blockages below the knee
This trial tests a special balloon coated with sirolimus (a drug that helps prevent arteries from re-closing) versus a standard balloon for opening blocked arteries below the knee in people with severe leg pain or foot wounds. The goal is to see if the drug-coated balloon works better to keep the artery open longer.
Scottsdale, ArizonaAges 21 years+ - NCT06194656RecruitingPhase 2
Trial of SIBP-03 for advanced head and neck cancer
This trial tests a new drug called SIBP-03 for people with head and neck squamous cell carcinoma that has come back or spread. It is for those whose cancer has worsened after prior immunotherapy and platinum chemotherapy, and who have no option for curative local treatment.
Shanghai, Shanghai MunicipalityAges 18–75
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,902 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.