Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07063342RecruitingPhase 1
Study of new drug versions in healthy adults
This study is testing new versions of a drug (called KarX and KarT) in healthy adults to see how the body handles them. Researchers will also look at how food affects the drug when taken multiple times.
Nottingham, NottinghamshireAges 18–55 - NCT07688772RecruitingPhase 3
Study of SHR-1819 Injection for Seasonal Allergic Rhinitis
This trial tests a new injection called SHR-1819 for people with seasonal allergies who haven't responded well to standard treatments like nasal sprays or antihistamines. It aims to see if it can reduce allergy symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT07542483RecruitingPhase 3
Lebrikizumab for nummular eczema in adults
This study tests whether lebrikizumab, a new injection, can reduce nummular eczema (coin-shaped eczema patches) in adults whose condition hasn't improved with topical steroid creams. It's designed to help people with moderate-to-severe nummular eczema who need a stronger treatment option.
Freiburg im BreisgauAges 18 years+ - NCT06519422RecruitingPhase 3
Tranexamic acid for anaemia in women
This trial tests whether tranexamic acid, a medicine that helps reduce bleeding, can improve anaemia (low blood iron) in women with heavy periods. If you have anaemia and heavy menstrual bleeding, this treatment might help raise your iron levels.
Ibadan, Oyo StateAges 18 years+ - NCT07065240RecruitingPhase 2
Study of SPT-300 for major depression with or without anxiety
This trial tests an experimental oral medication, SPT-300, for people with major depressive disorder, even if they also have mild anxiety. The goal is to see if it helps improve mood safely.
Chino, CaliforniaAges 18–65 - NCT04804241RecruitingPhase 2
Senicapoc for early Alzheimer’s symptoms
This Phase 2 study tests whether the drug senicapoc can slow or improve symptoms in people with early Alzheimer’s disease or mild memory impairment. You would have a 50/50 chance of getting senicapoc or a placebo (inactive pill), along with regular study visits and testing.
Sacramento, CaliforniaAges 55–85 - NCT06184321RecruitingEarly Phase 1
Alteplase through chest tube for trapped fluid
This trial tests whether a clot-busting medicine called alteplase, given through an existing chest tube (indwelling pleural catheter), can help drain fluid that has become trapped by fibrous bands. It may help relieve symptoms like shortness of breath.
Baltimore, MarylandAges 18 years+ - NCT06807268RecruitingPhase 3
A study of abrocitinib for children ages 6–11 with eczema
This trial tests a daily pill called Abrocitinib to see if it can help children ages 6 to 11 with moderate-to-severe eczema that hasn't gotten better with creams or ointments. Eczema (also called atopic dermatitis) causes itchy, red skin, and this medicine might calm the immune response to reduce itching and rashes.
Birmingham, AlabamaAges 6–11 - NCT07133880RecruitingPhase 4
Nebulizer vs inhaler for COPD breathing treatment
This study compares two ways to deliver long-acting bronchodilator medications for COPD: a nebulizer (machine that turns liquid medicine into a mist) versus a handheld inhaler. The goal is to see which method works better for people with moderate to severe COPD symptoms.
Knoxville, TennesseeAges 40 years+ - NCT07355218RecruitingPhase 3
Testing enpatoran for lupus skin problems
This trial tests an oral drug called enpatoran for people with lupus that causes skin rashes (like discoid or subacute cutaneous lupus). The goal is to see if the drug can improve these skin symptoms.
Upland, CaliforniaAges 18–75 - NCT05275972RecruitingPhase 3
Compare cornea surgery thickness results for FECD
This Phase 3 trial compares outcomes from two cornea transplant procedures in people with FECD, a disease that makes the cornea swell and affect vision. It may help you and others by identifying which approach best supports clear vision and stable corneal thickness after surgery.
Palo Alto, CaliforniaAges 18 years+ - NCT07282574RecruitingPhase 2
Testing a new study drug for progressive MS
This trial tests a new study drug added to your current MS treatment (ocrelizumab) for people with progressive MS. It aims to see if the combination works better than ocrelizumab alone.
Camperdown, New South WalesAges 18–60 - NCT06672952Recruiting
Citrus compound for exercise, blood flow, and stress in overweight adults
This study looks at whether a natural citrus compound called glucosyl-hesperidin (CitraPeak) can boost your exercise performance, improve blood flow, reduce stress, and sharpen thinking. Researchers want to see if it works differently for people who are moderately overweight or mildly obese.
Saint Charles, MissouriAges 18–50 - NCT05825092RecruitingPhase 2
Early testosterone gel for people on breathing machines
This Phase 2 study tests whether starting testosterone gel soon after ICU admission can improve physical performance in critically ill adults who need a breathing machine for more than 48 hours. It’s also designed to check safety in this setting.
BordeauxAges 18–79 - NCT07226765RecruitingPhase 3
Weight-loss drug for sleep apnea without CPAP
This study tests a new weight-loss medication called maridebart cafraglutide against a placebo in people with moderate to severe obstructive sleep apnea who are not using a CPAP machine. The goal is to find out if weight loss can reduce symptoms like pauses in breathing during sleep.
Northridge, CaliforniaAges 18–99 - NCT07282665RecruitingPhase 3
Vaccine to prevent C. difficile infection in adults 65 and older
This study tests a vaccine that may help protect against a serious gut infection called C. difficile, which often happens after antibiotics or hospital stays. If you are 65 or older and have certain health conditions or recent antibiotic use, you may be able to join.
Athens, AlabamaAges 65 years+ - NCT06451588RecruitingPhase 2
Fecal transplant for inflammatory back pain
This study tests whether a fecal microbiota transplant (a procedure that transfers healthy bacteria into your gut) can reduce inflammation and improve symptoms in people with inflammatory back pain (axial spondyloarthritis). It may help if your current treatments are not working well enough.
TromsøAges 18–65 - NCT07764991RecruitingPhase 2
Lactoferrin supplement for diabetic kidney disease
This study tests whether taking a lactoferrin supplement can help people with type 2 diabetes and chronic kidney disease (stage 3 or 4) by reducing protein in their urine, which is a sign of kidney damage. It may offer a new way to slow the progression of kidney disease.
CairoAges 18–75 - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with overweight or obesity
This trial tests an investigational once-daily pill (ASC30) to see if it can help adults with overweight or obesity lose weight. You may be able to join if you have a high body mass index (BMI) and have tried to lose weight before.
Birmingham, AlabamaAges 18 years+ - NCT07743450RecruitingPhase 3
Once-daily pill for weight loss in people with type 2 diabetes
This study tests an oral medication, ASC30, to see if it helps people with type 2 diabetes who are overweight or obese lose weight and improve blood sugar control. It is a once-daily pill that may offer a new treatment option.
Birmingham, AlabamaAges 18 years+ - NCT07766655RecruitingPhase 3
Medication for quitting smoking
This study tests if an investigational medication helps adults stop smoking. Participation takes place of over several weeks, and may increase your chances of quitting successfully.
Little Rock, ArkansasAges 18–65 - NCT07766720Recruiting
Eggshell membrane and turmeric supplements for exercise recovery
This trial tests whether taking eggshell membrane, curcumin (turmeric), or both together can help your muscles recover faster after intense exercise. It may reduce soreness and help you bounce back sooner.
College Station, TexasAges 18–40 - NCT06749457RecruitingPhase 1/Phase 2
Study of a new drug for healthy adults and kidney patients on dialysis
This trial tests a new drug called AZD7760 in two groups: healthy adults (Phase I) and adults with end-stage kidney disease who are on hemodialysis through a central venous catheter (Phase IIa). The goal is to see how safe the drug is and how the body processes it. This could lead to a new treatment option for people on dialysis.
Huntsville, AlabamaAges 18–55 - NCT06166654RecruitingPhase 4
Better water pill therapy for acute heart failure
This trial tests different water pill (diuretic) strategies for people hospitalized with acute heart failure and too much fluid. It is designed for patients who may not respond well to standard water pills, to find a more effective way to relieve symptoms.
Hvidovre, Capital Region of DenmarkAges 18 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,949 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.