Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,902 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07783542RecruitingPhase 2
Treatment for moderate to severe hidradenitis suppurativa
This study tests a new medication called ORKA-002 to see if it can reduce the number of painful bumps and sores in people with moderate to severe hidradenitis suppurativa (a chronic skin condition). It may be an option for people who have not had success with antibiotic treatments.
Birmingham, AlabamaAges 18–79 - NCT07783425RecruitingPhase 3
Treatment for moderate-to-severe eczema
This study tests a new medicine called Tilrekimig for people with moderate-to-severe eczema (also called atopic dermatitis) whose symptoms have not improved with creams or ointments. The goal is to see if this medicine helps reduce symptoms and improve skin condition.
Phoenix, ArizonaAges 12 years+ - NCT07779252RecruitingPhase 3
Study of a new treatment for frown lines between the eyebrows
This study tests a new medication (IPN10200) to safely reduce moderate to severe frown lines between the eyebrows in adults. It may help if you are bothered by these lines and are looking for a non-surgical option.
Guangzhou, GuangdongAges 18 years+ - NCT07779265Recruiting
Probiotic supplement for gut health in healthy adults
This trial tests a daily probiotic supplement's effect on digestion, immune health, and overall well-being. If you're a healthy adult, you may help discover if this product can make you feel better day-to-day.
TrierAges 18–65 - NCT07780669RecruitingPhase 3
Study of a new drug for moderate to severe COPD in smokers
This study tests a new medication (GSK5784283) for people with moderate to severe COPD who have a certain type of inflammation (eosinophilic). Participants must be on standard inhaler therapy and have a history of smoking. The trial will compare the new drug to a placebo.
Doral, FloridaAges 40–80 - NCT07778836RecruitingPhase 3
Study of daily injections for Friedreich's ataxia
This study tests an investigational drug given as a daily injection to see if it can improve walking and balance in people with Friedreich's ataxia.
Tampa, FloridaAges 12–40 - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Huntsville, AlabamaAges 18 years+ - NCT07782970RecruitingPhase 3
Treatment for chronic sinusitis with nasal polyps
This study tests a new medication (felcorekibart) to see if it reduces nasal polyps and symptoms like congestion and loss of smell. It may help people whose current treatments aren't enough.
Los Angeles, CaliforniaAges 18 years+ - NCT07782957RecruitingPhase 3
New shot for severe nasal polyps with ongoing sinus symptoms
This study tests an experimental medication called felcorekibart, given as an injection, to see if it reduces nasal polyps and improves sinus symptoms like congestion and loss of smell. It is for adults who have had nasal polyps for at least a year and have already tried standard treatments like steroid sprays or pills, or had surgery.
Sherman Oaks, CaliforniaAges 18 years+ - NCT07777822RecruitingPhase 3
First-line treatment for metastatic non-squamous lung cancer with RAS mutation
This trial tests whether adding a new drug (zoldonrasib) to standard chemotherapy and immunotherapy can help people with a specific type of lung cancer. It is for those with a RAS G12D mutation and no prior treatment for metastatic disease.
Plantation, FloridaAges 18 years+ - NCT06385054RecruitingPhase 2
Probiotics for infant colic in breastfed babies
This study tests a probiotic (friendly bacteria) to see if it can reduce crying and fussing in babies with colic. It is for exclusively breastfed infants 8 weeks and younger who have colic symptoms.
Bécon-les-GranitsAges Up to 2 months - NCT07777627Recruiting
Comparing two spinal pain relievers after lumbar spine surgery
This trial compares two different medications (morphine and dexmedetomidine) given through a spinal injection to see which provides better pain relief after lumbar spine surgery. If you qualify, you will receive one of these treatments or a placebo to help manage your pain after the operation.
Tanta, El-GharbiaAges 21–60 - NCT07781514Enrolling by invitation
Vitamin E as an add-on to levothyroxine for hypothyroidism
This trial tests whether adding vitamin E to your usual levothyroxine treatment helps improve thyroid function and reduce oxidative stress (a type of cell damage) in adults with hypothyroidism.
DhakaAges 18–75 - NCT07777328Recruiting
5-HTP for ADHD traits and eye movements in adults
This study looks at how a supplement called 5-HTP (a natural amino acid) affects attention and eye movements in adults. You will receive either 5-HTP or a placebo to see if it changes ADHD-like traits.
Sheffield, South YorkshireAges 18–65 - NCT06446479RecruitingPhase 2
THC's effect on alcohol use and brain reward
This study tests whether THC (the active ingredient in cannabis) can change how much alcohol you drink and how your brain responds to rewards. You will have MRI scans and take THC or a placebo, then drink alcohol in a controlled setting.
Aurora, ColoradoAges 21–40 - NCT03910010Recruiting
Brain scan study to study pain-related body signals in fibromyalgia
This study uses MRI brain scans to look for body “signals” (biomarkers) that may relate to chronic pain, including fibromyalgia. It may help researchers better understand what’s going on in the brain for people with long-term pain.
Halifax, Nova ScotiaAges 18–75 - NCT07770464RecruitingPhase 2
Montelukast for acute bronchiolitis in infants
This study tests whether montelukast, a medicine that helps reduce airway inflammation, can improve symptoms of acute bronchiolitis (a common lung infection in babies) when given early. It may help babies breathe easier and recover faster.
Islamabad, FederalAges 4 weeks–2 years - NCT05923333Recruiting
Breastfed infants of HIV-exposed mothers get a probiotic
This study gives a specific probiotic (from B. infantis) to babies born without HIV to see if it can improve the baby’s early immune health. It focuses on babies who are HIV-exposed because their mother has HIV and plans to exclusively breastfeed for the first 6 months.
Cape TownAges birth–50 years - NCT07774403RecruitingPhase 2
Study of AZD0292 in Chinese patients with bronchiectasis and chronic Pseudomonas infection
This study tests a new medication called AZD0292 for people with bronchiectasis who have a long-term Pseudomonas infection. It aims to see if the drug can reduce flare-ups and improve lung health.
AnyangAges 18 years+ - NCT07767903RecruitingPhase 3
Study of a new medicine for generalized anxiety disorder
This trial tests an investigational medication to see if it can reduce anxiety symptoms in adults with generalized anxiety disorder. Participants will receive the study drug and be monitored for safety and effectiveness.
Redlands, CaliforniaAges 18 years+ - NCT07773246RecruitingPhase 1/Phase 2
Study of KRRO-121 in healthy adults and people with urea cycle disorder
This study tests an investigational drug called KRRO-121. It is first tested in healthy volunteers to check safety, and then in patients with urea cycle disorder (a condition where the body can't remove ammonia properly) to see if it helps.
Melbourne, VictoriaAges 18–65 - NCT07772492RecruitingPhase 3
Study of upadacitinib for teens with severe hair loss
This study tests if upadacitinib can help young people with severe alopecia areata (a condition causing patchy hair loss) regrow their hair. It may be an option if hair loss has been present for less than 8 years and there has been no recent improvement.
Los Angeles, CaliforniaAges 6–17 - NCT07775300RecruitingPhase 3
Study of an injectable drug for major depressive disorder
This study tests an investigational drug called brenipatide for major depressive disorder. It is given as a self-injection and is being compared to a placebo to see if it helps improve depression symptoms in people who are already on standard treatment.
Birmingham, AlabamaAges 18–75 - NCT07775404RecruitingPhase 3
Weight loss medication for Asian adults with obesity or overweight
This study tests an investigational medication called elecoglipron for weight loss in Asian adults who are overweight or have obesity, with or without type 2 diabetes. It may help participants lose weight and improve health.
BaotouAges 18 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,902 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.