Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,904 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05229224Recruiting
Study of a new device for frequent tension headaches
This pilot study tests a device approach (“Osteo-Fluidic-Sensitive”) for people who get frequent episodic tension-type headaches. It aims to see whether the device is safe and can reduce headache burden for the right kind of headache pattern.
PoitiersAges 18–75 - NCT05247255Enrolling by invitationEarly Phase 1
Nerve block during hip replacement surgery
This early-stage study tests whether a specific nerve block to numb the lower back area can make total hip replacement surgery more comfortable. It looks at patients who are having planned (elective) hip replacement and whether the nerve block is safe and works well.
Santa Monica, CaliforniaAges 18 years+ - NCT05206955RecruitingPhase 3
Tadalafil versus placebo for Fontan circulation problems
This study tests whether tadalafil (a daily pill) can improve blood flow and protect organs in adults who have had Fontan surgery. Participants will either receive tadalafil or a placebo, and they will be monitored during a planned heart catheter procedure.
Rochester, MinnesotaAges 18 years+ - NCT05211401RecruitingPhase 2
Testing rituximab for heart attack patients
This study tests whether adding the drug rituximab to standard heart attack treatment can reduce damage to the heart muscle after a heart attack. Rituximab is usually used for immune system conditions, and it may help calm inflammation and protect the heart. Participants must have a certain type of heart attack and be treated quickly.
ParisAges 18 years+ - NCT05230758RecruitingPhase 3
Metformin trial for brain tumor survivors’ brain and behavior
This Phase 3 study tests whether metformin can improve brain function, behavior, and thinking in children and teens who were treated for certain brain tumors. You may be able to join if you meet age, time-since-treatment, language, and health/lab safety requirements.
New Lambton Heights, New South WalesAges 7–21 - NCT05139719RecruitingPhase 2
HEC585 trial for slowing lung scarring decline
This Phase 2 study tests whether HEC585 can slow the decline in lung function in people with progressive fibrosing interstitial lung disease (PF-ILD). It may help preserve breathing capacity and breathing tolerance over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05183646RecruitingPhase 3
DMX-200 for FSGS in people taking an ARB medicine
This Phase 3 trial studies whether DMX-200 is safer and works better than placebo for people with FSGS who are already on (or can switch to) an ARB blood-pressure/kidney-protection medicine. It also looks at side effects over a long follow-up period.
Birmingham, AlabamaAges 12–80 - NCT05156398RecruitingPhase 3
Rimegepant to prevent migraine attacks in children
This trial studies whether rimegepant can reduce how often migraine attacks happen in children and teens. It also looks at safety and how well the treatment fits day-to-day life and school activities.
Fort Smith, ArkansasAges 6–17 - NCT05163288RecruitingPhase 3
N-acetyl-leucine trial for Niemann-Pick disease type C
This Phase 3 trial tests whether N-acetyl-leucine can improve symptoms in people with Niemann-Pick disease type C (NPC). If you qualify, you will be asked to take study medicine and complete symptom and movement tests over time.
Rochester, MinnesotaAges 4 years+ - NCT05153070RecruitingPhase 2
Cyclosporine then low-dose immune therapy for new type 1 diabetes
This Phase 2 study tests whether starting with cyclosporine and then giving low-dose IL-2 can better protect the body’s insulin-producing function after type 1 diabetes is diagnosed. It’s meant for people diagnosed very recently who have specific diabetes-related immune markers.
ParisAges 16–45 - NCT05140148RecruitingPhase 2
Amantadine to help recovery after stroke
This Phase 2 study tests whether the medicine amantadine can improve recovery after a recent stroke. It may help some people regain function during early rehabilitation.
Philadelphia, PennsylvaniaAges 18–85 - NCT05177510RecruitingPhase 2
Mifepristone to help start labor in some late pregnancies
This Phase 2 study tests whether mifepristone, taken by mouth, can help start labor when the cervix is not ready yet. It may help avoid needing other methods of induction, but it will only be offered if it’s safe for you and your baby.
LondonAges 18 years+ - NCT05174052RecruitingPhase 3
Dapagliflozin for heart rhythm problems in diabetes
This trial studies dapagliflozin, a diabetes medicine, to see if it can help people with paroxysmal atrial fibrillation (irregular heart rhythm). If you have both diabetes and this type of AF, the study may offer a chance to improve your heart rhythm and outcomes.
Oklahoma City, OklahomaAges 18–85 - NCT05148286RecruitingPhase 4
Testing albumin vs fluids for septic shock in the ER
This trial tests whether giving albumin instead of standard crystalloid fluids helps adults with septic shock. It may improve how well your body circulates blood and reduces strain on organs.
SeoulAges 18 years+ - NCT05173714RecruitingPhase 2
Sit Less and Move More program for people with CKD
This Phase 2 study tests a program to help people with chronic kidney disease (CKD) sit less and move more, plus a medication (semaglutide) for those who qualify. It may help improve health and day-to-day activity while monitoring safety closely.
Stanford, CaliforniaAges 20 years+ - NCT05147519Recruiting
Observes HIV and other infections to learn who gets them
This is an observational study that follows people to better understand how HIV and other infections (like sexually transmitted infections) happen and change over time. It may help researchers improve prevention and care, but it is mainly for monitoring rather than testing a new treatment.
Kericho, Kericho CountyAges 14–55 - NCT05160506RecruitingPhase 2
Steroids to treat acute pancreatitis in the ICU
This Phase 2 study tests whether corticosteroids (steroid medicines) can improve outcomes for adults with severe acute pancreatitis in the intensive care unit. It’s meant to see if steroids help when the pancreas inflammation is serious.
Boston, MassachusettsAges 18–99 - NCT05132660Enrolling by invitationEarly Phase 1
Early eye treatment study for diabetic retinopathy
This early-phase study tests a treatment aimed at preventing or slowing early diabetic eye disease in people with mild, early changes. You may be considered if your diabetes is moderately controlled and your eye tests show early warning signs.
Decatur, GeorgiaAges 30–80 - NCT05127954Enrolling by invitationPhase 3
Long-term migraine tablet study for kids and teens ages 6–17
This study follows kids and teens who already took part in an earlier migraine medication study to check long-term safety and comfort with oral ubrogepant tablets. It may help families understand whether this migraine tablet is safe to keep using over time.
Huntsville, AlabamaAges 6–17 - NCT05095701Enrolling by invitationPhase 4
Study tracks lasting protection from a live chickenpox vaccine
This trial follows people who previously took a chickenpox (varicella) vaccine to see how long their immune protection lasts. It may help explain who stays protected over time and for how long.
Xuchang, HenanAges 1–17 - NCT05125302RecruitingPhase 3
Ubrogepant for acute migraine relief in kids and teens
This study tests how safe ubrogepant is and whether it helps treat an individual migraine attack in children and teens. It focuses on measuring side effects and whether headaches improve 2 hours after taking the study medicine.
Huntsville, AlabamaAges 6–17 - NCT05077904RecruitingPhase 3
Staccato alprazolam study for prolonged seizures in teens and adults
This Phase 3 trial tests whether staccato alprazolam can reduce and manage “prolonged seizures” that happen repeatedly in people with epilepsy. It also checks safety—especially breathing and heart-related side effects—while participants continue their usual seizure medicines.
Phoenix, ArizonaAges 12 years+ - NCT05090891RecruitingPhase 2
Study medicine INCB000928 for fibrodysplasia ossificans progressiva
This Phase 2 study tests whether INCB000928 can safely help people with fibrodysplasia ossificans progressiva (FOP). It mainly looks at whether the treatment is effective and well-tolerated, and it involves scheduled whole-body scans using low-dose X-rays.
Rochester, MinnesotaAges 2–99 - NCT05079763Recruiting
Hydrogel treatment to reduce skin damage after breast radiation
This trial tests a bacterial cellulose–based gel with a soothing ingredient (monolaurin) to help prevent or lessen painful skin reactions in the area receiving breast radiation. It focuses on people who have already finished surgery and chemotherapy and are about to start a planned radiation treatment schedule.
ManilaAges 18–80
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,904 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.