Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,902 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04411225RecruitingPhase 3
CBD may help early psychosis along with usual treatment
This Phase 3 trial tests whether taking cannabidiol (CBD) can reduce symptoms when added to standard care for early psychosis (like first-episode psychosis or attenuated psychosis). It may help some people have fewer troubling thoughts or perceptions over time.
La Jolla, CaliforniaAges 16–30 - NCT04497220Recruiting
First-time epidural in pregnancy: poke versus placebo
This trial tests whether a “poke” (an added procedure or treatment) works better than a placebo to help with pain control for people getting an epidural for the first time during pregnancy. It’s mainly looking at whether the added approach is helpful and safe for first-time epidural patients.
Minneapolis, MinnesotaAges 18 years+ - NCT04791579RecruitingPhase 2
Preventing UTIs after Botox for neurogenic bladder
This study tests whether taking an antibiotic (ciprofloxacin) around the time of bladder Botox can prevent urinary tract infections (UTIs) in people whose bladder problems are caused by nerve conditions. It may help lower the chance of infection after treatment.
Edmonton, AlbertaAges 18–100 - NCT04798469RecruitingPhase 2
Testosterone to reduce long-term spine pain in men on opioids
This Phase 2 study tests whether taking testosterone can lessen chronic non-cancer spinal pain in men who have low testosterone while using opioid pain medicines. It may help by improving hormone levels that could be affecting pain and overall wellbeing.
Boston, MassachusettsAges 18 years+ - NCT04794530RecruitingPhase 3
Cocoa extract trial for walking problems in blocked leg arteries
This Phase 3 study tests whether cocoa extract (cocoa flavanols) can improve walking ability and circulation in people with peripheral artery disease (PAD). It may help people who have PAD-related walking limits and can safely avoid competing cocoa sources and caffeine.
Chicago, IllinoisAges 55 years+ - NCT04789148RecruitingPhase 1
Nasal oxytocin trial for people with hormone deficiency
This early-phase study tests whether a spray of oxytocin in the nose can be given safely and may affect symptoms in people with arginine-vasopressin deficiency. You might qualify if your hormone levels are stable and you can safely take the nasal study medicine during the study period.
Boston, MassachusettsAges 18 years+ - NCT04797286RecruitingPhase 2
Sildenafil for early lung blood-pressure problems in scleroderma
This trial tests whether sildenafil can improve early “high pressure in the lung blood vessels” in people with scleroderma. It may help slow worsening breathing and lung blood-vessel disease before it becomes severe.
New Orleans, LouisianaAges 18 years+ - NCT04804241RecruitingPhase 2
Senicapoc for early Alzheimer’s symptoms
This Phase 2 study tests whether the drug senicapoc can slow or improve symptoms in people with early Alzheimer’s disease or mild memory impairment. You would have a 50/50 chance of getting senicapoc or a placebo (inactive pill), along with regular study visits and testing.
Sacramento, CaliforniaAges 55–85 - NCT04774159RecruitingPhase 3
Low-dose colchicine to lower risk in leg artery disease
This trial tests whether low-dose colchicine can reduce “residual” risk—future heart and blood-vessel problems—in people with peripheral artery disease (PAD). It targets PAD symptoms and complications like poor blood flow in the legs, even after certain procedures.
New Haven, ConnecticutAges 18 years+ - NCT04782830Recruiting
Wearable sensor study for low blood pressure on standing
This study uses an accelerometer (a wearable motion sensor) to measure symptoms and blood pressure changes when you stand up. It may help doctors better track how neurogenic orthostatic hypotension affects you and how well current treatments are working.
Nashville, TennesseeAges 40–80 - NCT04771156RecruitingPhase 4
Ketorolac pain relief during cleft palate repair
This trial tests whether ketorolac (a pain medicine similar to other NSAIDs) helps control pain during palatoplasty, the surgery to repair a cleft palate. It may help make recovery more comfortable for people having their first palate repair.
Houston, TexasAges 6 months+ - NCT04817618RecruitingPhase 3
Iptacopan for kidney inflammation in C3 glomerulopathy
This trial studies whether iptacopan can improve outcomes and safety for people with C3 glomerulopathy, a kidney disease caused by overactive parts of the immune system. Participants must already be on standard kidney-protecting medicines and meet specific kidney function and urine protein criteria.
Aurora, ColoradoAges 12–60 - NCT04853342RecruitingPhase 3
Furmonertinib after lung tumor removal for EGFR-mutated lung cancer
This trial tests whether furmonertinib, an oral targeted medicine, can improve outcomes after your lung tumor has been completely removed. It also checks for side effects and compares results against placebo in people with specific EGFR gene mutations.
Suzhou, JiangsuAges 18–75 - NCT04775706RecruitingPhase 2
Test of sonefpeglutide for people with short bowel syndrome
This Phase 2 study tests whether sonefpeglutide is safe and how the body handles it (pharmacokinetics) in people with short bowel syndrome. It may help people who still need nutrition through a tube because their intestinal condition is stable.
Boston, MassachusettsAges 18 years+ - NCT04777357RecruitingPhase 3
Cariprazine for bipolar depression in ages 10 to 17
This Phase 3 study tests whether cariprazine can improve depression symptoms in children and teens with bipolar I disorder, and also tracks side effects. It may help if your depressive episode is ongoing and you meet specific mood and screening score requirements.
Bentonville, ArkansasAges 10–17 - NCT04772079RecruitingPhase 3
Test drug safety and effectiveness for youth plaque psoriasis
This study checks whether deucravacitinib works well and is safe in children and teens with moderate to severe plaque psoriasis. It also looks at drug levels in the body to help understand how the treatment behaves over time.
Ciudad Autonoma de Buenos Aires, Buenos AiresAges 4–18 - NCT04804553RecruitingPhase 3
Apremilast for children with active juvenile psoriatic arthritis
This Phase 3 trial tests apremilast to treat active juvenile psoriatic arthritis (joint inflammation) in children and teens. You may be able to join if your child’s condition is active despite prior treatments or if they couldn’t tolerate them.
GhentAges 5–17 - NCT02484248RecruitingPhase 3
Ketotifen for kids with stomach pain and duodenal eosinophilia
This study tests whether ketotifen can improve long-lasting stomach pain in children whose biopsies show high levels of a certain immune cell type in the small intestine. It may help if standard stomach-acid medicines and montelukast did not work well enough.
Kansas City, MissouriAges 8–17 - NCT04153422RecruitingPhase 2
IVIG for small fiber nerve pain with specific antibody tests
This trial studies whether IVIG (an immune therapy made from donated antibodies) can reduce pain from autoimmune small fiber neuropathy. You may be a candidate if your tests show certain autoantibodies (TS-HDS, FGFR3, or Plexin-D1) and your symptom scores are high enough.
Glenview, IllinoisAges 18 years+ - NCT04759001RecruitingPhase 1/Phase 2
Fecal treatment to clear gut bacteria resistant to antibiotics
This study tests a stool-based treatment (fecal microbiota treatment) to help remove “carbapenem-resistant” bacteria living in the gut. If you carry these bacteria without being sick, the goal is to reduce or stop that colonization.
RomeAges 18–90 - NCT04704271RecruitingPhase 1
Study on THC effects in people with past cannabis use
This Phase 1 study looks at how THC (the main mind-altering ingredient in cannabis) affects healthy volunteers shortly after use. It focuses on differences between people and includes those who have used cannabis before.
West Haven, ConnecticutAges 18–55 - NCT04745143RecruitingPhase 2
NMDA-enhancer medicine tested for schizophrenia without antipsychotics
This Phase 2 trial tests a single medicine intended to help people with schizophrenia who cannot take standard antipsychotic medications due to side effects or poor response. It may help reduce schizophrenia symptoms, but whether you can join depends on your diagnosis, medication history, and health conditions.
TaichungAges 18–65 - NCT04741646RecruitingPhase 2
Ferric citrate for kids with chronic kidney disease
This Phase 2 study tests ferric citrate, a medicine that helps control phosphate and iron balance, in children with chronic kidney disease. It may help slow problems related to kidney disease by improving lab measures like phosphate levels.
Los Angeles, CaliforniaAges 6–18 - NCT04770012RecruitingPhase 3
Aspirin or clopidogrel after heart transplant
This study tests antiplatelet medicines (like aspirin or clopidogrel) in people who have had a heart transplant. The goal is to see if these medicines can safely help prevent blood-related complications after transplant.
Vancouver, British ColumbiaAges 18 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,902 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.