Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,902 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04649242RecruitingPhase 3
Migraine pain relief study for kids and teens
This trial studies a medicine for stopping a migraine attack in children and teens. It may help families understand which treatment works best during acute (during-attack) migraine pain.
Birmingham, AlabamaAges 6–17 - NCT04678895RecruitingPhase 2
Low-dose naltrexone for nerve pain from diabetes
This Phase 2 trial studies whether a low dose of naltrexone can reduce painful nerve pain caused by diabetes. It may help people whose diabetic nerve pain did not improve with at least one standard treatment.
Lebanon, New HampshireAges 18 years+ - NCT04614714RecruitingPhase 2/Phase 3
Nicotinamide riboside to boost breast milk for very premature infants
This study tests whether an oral supplement called nicotinamide riboside can increase milk output in mothers of extremely premature babies. If it works, it may help you provide enough breast milk for your baby’s early NICU needs.
Sacramento, CaliforniaAges 18 years+ - NCT04666636RecruitingPhase 2
Test a drug idea to activate fat that burns energy
This Phase 2 study tests whether a medication approach can activate “beige” fat, which may help the body burn more energy. It mainly looks for people with higher body weight and prediabetes who are not on diabetes medicines.
Lexington, KentuckyAges 35–65 - NCT04597437RecruitingPhase 2
Zanamivir for dengue that causes warning signs
This Phase 2 study tests whether zanamivir given through a vein can improve outcomes in people with dengue infection who have warning signs. It may help by reducing the body problems dengue can cause in blood vessels and fluid balance.
Barranquilla, AtlánticoAges 7 years+ - NCT04601038RecruitingPhase 2
Testing a stress-blocking drug for early Alzheimer's risk
This study tests a new medication, CORT108297, that may help protect the brain from the harmful effects of stress in people at risk for Alzheimer's disease. It is looking for adults age 55 and older who either have mild memory problems or are healthy but have a family history, APOE4 gene, or memory concerns.
Baltimore, MarylandAges 55 years+ - NCT04597372RecruitingPhase 2
Tamsulosin for bladder urine retention after pelvic surgery
This trial studies whether tamsulosin can help drain the bladder when urine builds up after pelvic reconstructive surgery. It may help reduce the time and problems caused by “post-operative urinary retention.”
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04678167Recruiting
Special “ring” glasses for vestibular neuritis symptoms
This trial tests whether wearing “ring” glasses helps reduce symptoms from vestibular neuritis, a condition that causes spinning vertigo and balance problems. Participants may get the glasses being tested or look-alike placebo glasses (or not wear glasses), so the study can tell if the glasses truly help.
BrestAges 18 years+ - NCT04659317RecruitingPhase 3
Opioid-free pain plan for joint and arm surgeries
This Phase 3 study tests an opioid-free approach to pain control for certain orthopedic (bone/joint) surgeries. The goal is to help people manage surgical pain without using opioid pain medicines.
Atlanta, GeorgiaAges 18 years+ - NCT04496895Recruiting
Orange peel drink study for reducing body fat
This trial looks at whether a fermented orange peel product can lower body fat in adults. It may help if you have higher body fat and/or fatty liver, and you meet safety and health limits.
Taipei, TaiwanAges 20–65 - NCT04528082RecruitingPhase 3
Apremilast for children with frequent mouth ulcers from Behçet’s disease
This study tests apremilast to help reduce active, recurring mouth (oral) ulcers in children with Behçet’s disease. It may help if your child has had repeated mouth ulcers despite at least one non-biologic treatment.
BronAges 2–17 - NCT04547439RecruitingPhase 2
Melatonin for diabetic eye disease and better sleep
This Phase 2 study tests whether melatonin can improve sleep and possibly outcomes related to diabetic retinopathy (damage to the retina from diabetes). It also checks whether it affects related symptoms while keeping people safe.
Chicago, IllinoisAges 40–65 - NCT04516057RecruitingPhase 3
Tested medicine nabilone for agitation in Alzheimer’s dementia
This Phase 3 trial studies whether nabilone can reduce agitation (restlessness, anger, or difficult behavior) in people with Alzheimer’s dementia. It’s designed for older adults who already have agitation despite standard dementia care.
Calgary, AlbertaAges 55 years+ - NCT04555785RecruitingPhase 4
Testing platelet treatment in ICU patients after surgery
This trial studies whether a platelet-related treatment can work better in people in the ICU who need a platelet transfusion after surgery. It may help reduce bleeding by improving how platelets work when certain blood clotting proteins are already high.
BaselAges 18 years+ - NCT04538755Enrolling by invitationPhase 1/Phase 2
Testing a new drug for moderate to severe sleep apnea
This trial tests a drug called DAW2020 to see if it can improve how your body controls breathing during sleep. You may qualify if you have moderate to severe sleep apnea and are otherwise healthy.
Boston, MassachusettsAges 21–70 - NCT04534556Enrolling by invitation
Wireless nerve stimulation to improve stroke recovery
This study tests a wireless nerve stimulation device placed near the vagus nerve to help people recover after a stroke. It focuses on people with specific remaining arm/hand movement and recovery levels at least 12 months after stroke.
Dallas, TexasAges 22–79 - NCT04576078RecruitingPhase 2
Nefopam for less pain after knee replacement surgery
This Phase 2 study tests whether oral nefopam can reduce pain after total knee replacement done with spinal anesthesia. It looks at whether this medicine works better than the usual post-surgery pain plan and how safely it can be used.
Lyon, LyonAges 18–75 - NCT04551482RecruitingPhase 2
Oxytocin to help teens lose weight
This study tests whether the hormone oxytocin can help adolescents with obesity lose weight. You may be asked to stay on your usual diet and routines during the 18-week study to see how well the treatment works.
Boston, MassachusettsAges 10–18 - NCT04589819Enrolling by invitationPhase 4
Teriparatide for tibia stress fracture recovery for duty
This trial tests teriparatide, a medication that helps build bone, to see if it can speed recovery and help certain enlisted Army members return to training duty after a tibia bone injury. You may be asked to self-administer the medication while you recover and take part in study follow-ups.
Columbia, South CarolinaAges Any age - NCT04572256RecruitingEarly Phase 1
Montelukast after ACL surgery to protect knee cartilage
This early trial tests whether montelukast, a tablet used for allergies, can help protect knee cartilage after ACL surgery. It is specifically for people who have a meniscus injury along with their ACL tear.
Lexington, KentuckyAges 25–50 - NCT04520139RecruitingPhase 1/Phase 2
NAC to help prevent chemo brain fog in ovarian cancer
This Phase 1/2 study tests whether taking NAC (a supplement medicine) can help prevent or reduce memory and thinking problems after platinum chemotherapy. It targets people with advanced ovarian, fallopian tube, or primary peritoneal cancer who are starting at least six cycles of platinum-based treatment.
Orange, CaliforniaAges 18 years+ - NCT04570085RecruitingPhase 3
Caffeine treatment to improve thinking in Alzheimer’s disease
This trial tests whether changing caffeine intake can improve thinking and brain function in people with Alzheimer’s disease. You may qualify if you can follow a low-caffeine diet and have stable Alzheimer’s treatment and sleep/heart conditions.
AmiensAges 50 years+ - NCT04588233Recruiting
Melatonin study for teens with sleep trouble
This study tests whether melatonin can help teens (ages 13–17) who have trouble sleeping. You may be able to join if you’ve never taken melatonin before and your sleep issue seems to be behavior-related rather than caused by another medical sleep problem.
Loma Linda, CaliforniaAges 13–17 - NCT04509102Enrolling by invitationEarly Phase 1
Test added stimulant medicine with rTMS for depression
This early study tests whether adding a stimulant medicine to repetitive TMS (a non-drug brain stimulation) can improve depression. It is aimed at people whose depression has not improved after at least two antidepressant tries.
Los Angeles, CaliforniaAges 18–65
Hear when a new Placebo - Control trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,902 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.