Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,941 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04482478Recruiting
Edl treatment trial for functional indigestion symptoms
This trial studies whether EDL medicine can improve symptoms of functional dyspepsia (indigestion) and is safe for people with this condition. You may be asked to complete symptom questionnaires and undergo stomach testing to confirm there is no other cause for your symptoms.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT03935295RecruitingPhase 4
Dysport with a brace for teens with specific scoliosis curves
This trial studies whether adding Dysport (a botulinum toxin shot) to standard bracing can improve scoliosis in teens. It’s mainly for certain curve patterns and requires careful brace follow-through.
Baltimore, MarylandAges 10–16 - NCT03851640RecruitingPhase 3
Study drug for advanced prostate cancer that kept spreading despite standard treatments
This Phase 3 study tests HC-1119 soft capsules in men with metastatic castration-resistant prostate cancer—cancer that keeps progressing even when testosterone is blocked. It aims to see whether the drug works better than expected and is safe, especially after prior treatments like abiraterone and/or docetaxel.
ShanghaiAges 18 years+ - NCT05334485RecruitingPhase 2/Phase 3
Pyridostigmine to treat slow bowel recovery after colorectal surgery
This trial tests whether pyridostigmine helps return bowel function faster after colorectal surgery when the gut is “stuck,” causing bloating and no gas or stool. It also checks safety and side effects compared with standard care.
Cleveland, OhioAges 18 years+ - NCT03646058RecruitingPhase 3
Add-on buprenorphine to ease suicidal thoughts in depression
This Phase 3 study tests whether adding buprenorphine to your usual pain-dose medicines can reduce severe suicidal thoughts during a major depressive episode. It may help people who are currently hospitalized or closely followed and have higher scores for both depression severity and suicidal thinking.
Bordeaux, FranceAges 18–65 - NCT01344200RecruitingPhase 2
Celecoxib drug study in children on leukemia treatment
This trial studies how celecoxib moves through a child’s body and how much reaches the fluid around the brain and spinal cord. It’s for children (age 2–12) who are in the maintenance phase of certain blood cancers, to better understand dosing and safety.
Ottawa, OntarioAges 2–12 - NCT04777357RecruitingPhase 3
Cariprazine for bipolar depression in ages 10 to 17
This Phase 3 study tests whether cariprazine can improve depression symptoms in children and teens with bipolar I disorder, and also tracks side effects. It may help if your depressive episode is ongoing and you meet specific mood and screening score requirements.
Bentonville, ArkansasAges 10–17 - NCT04497220Recruiting
First-time epidural in pregnancy: poke versus placebo
This trial tests whether a “poke” (an added procedure or treatment) works better than a placebo to help with pain control for people getting an epidural for the first time during pregnancy. It’s mainly looking at whether the added approach is helpful and safe for first-time epidural patients.
Minneapolis, MinnesotaAges 18 years+ - NCT04555785RecruitingPhase 4
Testing platelet treatment in ICU patients after surgery
This trial studies whether a platelet-related treatment can work better in people in the ICU who need a platelet transfusion after surgery. It may help reduce bleeding by improving how platelets work when certain blood clotting proteins are already high.
BaselAges 18 years+ - NCT04232917RecruitingPhase 4
Testing a treatment to help clear genital high-risk HPV
This trial studies 2LPAPI® to see if it helps the body clear high-risk HPV infections in the cervix. It may be an option if you have a current HPV infection with mild/early abnormal cervical findings and can complete follow-up for about a year.
BrusselsAges 25–45 - NCT04120714Recruiting
tDCS brain stimulation for problematic internet gaming use
This trial tests whether a noninvasive brain stimulation method (tDCS) can help teens or adults reduce problematic internet gaming. It’s designed for people who meet diagnostic criteria for “pathological use of internet gaming.”
DijonAges 12 years+ - NCT04444440RecruitingPhase 4
Antibiotic prevention after bladder Botox for overactive bladder
This trial studies whether taking an antibiotic around the time of bladder Botox can lower the risk of urinary infections. It’s for women with overactive bladder who tried standard medicines but didn’t get enough relief.
Edmonton, AlbertaAges 18 years+ - NCT04597372RecruitingPhase 2
Tamsulosin for bladder urine retention after pelvic surgery
This trial studies whether tamsulosin can help drain the bladder when urine builds up after pelvic reconstructive surgery. It may help reduce the time and problems caused by “post-operative urinary retention.”
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03977493RecruitingPhase 3
Xeomin injections for focal hand muscle spasms
This trial tests incobotulinumtoxinA (Xeomin) injections to reduce focal hand dystonia—unwanted muscle tightening in the hand. You may be able to join whether you’ve had this condition before or have tried similar injections in the past, as long as certain safety rules are met.
BernAges 18 years+ - NCT04281979Recruiting
Testing a substance’s effects in adult cigarette and vape users
This study tests how a specific substance affects people who currently smoke cigarettes or e-cigarettes. You may be able to join if you’re within a certain age range and recently had specific smoking and drinking patterns, and if you meet health/safety requirements for study procedures like MRI.
Portland, OregonAges 21–40 - NCT06842199RecruitingPhase 3
Testing a new pill for moderate to severe plaque psoriasis
This trial tests an experimental drug called ICP-488 for people with moderate to severe plaque psoriasis. It aims to see if the drug can improve symptoms and is safe, and may be an option if you need stronger treatment than creams or light therapy.
Hefei, AnhuiAges 18–75 - NCT05327972RecruitingPhase 2
Botox injections for painful degenerative rotator cuff disease
This Phase 2 study tests whether botulinum toxin (Botox) injections can reduce pain from long-lasting degenerative rotator cuff problems. You may be eligible if you have shoulder pain for over a month and ultrasound evidence of specific tendon irritation.
Paris, ParisAges 41 years+ - NCT04576169Recruiting
Comparing treatment options for a TFCC tear in the wrist
This trial looks at which treatment works best for a specific kind of wrist cartilage (TFCC) tear. It may help you choose the most effective option if you have ulnar-sided wrist pain that didn’t improve with non-surgical care.
CopenhagenAges 18–65 - NCT03859921RecruitingPhase 3
Dydrogesterone pill support during natural-cycle embryo transfer
This Phase 3 study tests whether taking an oral progesterone-like medicine (dydrogesterone) during the “luteal phase” after a natural-cycle frozen embryo transfer can improve support for implantation. It may help couples who are using their own embryos in a natural (hormone-sparing) cycle after thawing.
Hong Kong, Hong KongAges 18–42 - NCT03552705RecruitingPhase 2
Tranexamic acid to reduce knee inflammation after ACL injury
This Phase 2 study tests whether tranexamic acid can reduce swelling and protect knee cartilage after an ACL injury. It may help by limiting bleeding-related inflammation in the injured joint soon after injury.
Stanford, CaliforniaAges 18–30 - NCT03153527RecruitingPhase 4
Testing slow steroid taper versus stopping suddenly
This trial studies whether it’s safer or works better to slowly reduce steroids versus stopping them abruptly after long-term use. It may help people who are currently on daily steroid tablets and don’t medically need a taper just to treat their underlying condition.
FrankfurtAges 18 years+ - NCT05598112RecruitingEarly Phase 1
Oral stool-based microbiome treatment for healthy aging
This early-stage study tests whether changing the gut bacteria using an oral stool-based treatment (called oral FMT) can improve health in older adults. It aims to see if this approach affects aging-related changes, including gut and body function.
Beijing, Beijing MunicipalityAges 70–85 - NCT03024775Recruiting
Study wheat triggers in people with non-celiac wheat sensitivity
This study looks at how different types (genotypes) of wheat affect gut symptoms in people who react to wheat but do not have celiac disease. It may help clarify which wheat triggers symptoms and how to confirm the trigger in a structured food challenge.
Sciacca, AgrigentoAges 18–65 - NCT05289063RecruitingPhase 1
Study new sleep apnea and blood vessel function
This Phase 1 study looks at how blood vessel function is affected by obstructive sleep apnea in adults who are newly diagnosed and have not used CPAP. It may help researchers understand the early effects of sleep apnea and guide future treatments.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,941 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.