Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,962 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04766177RecruitingPhase 3
Bumetanide for children with autism symptoms
This trial tests whether bumetanide can improve autism symptoms in children. It is for children aged 3 to 12 with autism diagnosed using a standard symptom rating scale.
TantaAges 3–12 - NCT04771156RecruitingPhase 4
Ketorolac pain relief during cleft palate repair
This trial tests whether ketorolac (a pain medicine similar to other NSAIDs) helps control pain during palatoplasty, the surgery to repair a cleft palate. It may help make recovery more comfortable for people having their first palate repair.
Houston, TexasAges 6 months+ - NCT04773691Recruiting
High-frequency brain stimulation to help cut alcohol use
This trial tests whether high-frequency rTMS (a non-surgical brain stimulation) can reduce how much alcohol you drink. It targets people with alcohol use disorder who are not fully stopping, and who want to cut down after a past relapse or failed withdrawal attempt.
DijonAges 18 years+ - NCT04774159RecruitingPhase 3
Low-dose colchicine to lower risk in leg artery disease
This trial tests whether low-dose colchicine can reduce “residual” risk—future heart and blood-vessel problems—in people with peripheral artery disease (PAD). It targets PAD symptoms and complications like poor blood flow in the legs, even after certain procedures.
New Haven, ConnecticutAges 18 years+ - NCT04774705Recruiting
Noninvasive vagus nerve stimulation for sepsis in the ICU
This study tests whether a noninvasive device that stimulates the vagus nerve can help adults with sepsis in the intensive care unit. Researchers want to see if adding this treatment improves outcomes compared with standard ICU care.
GarchesAges 18 years+ - NCT04781322RecruitingPhase 1
Study drug to reduce LDL cholesterol effects in heavy drinkers
This Phase 1 study tests how safe a cholesterol-lowering antibody (alirocumab) is in people who drink heavily but are not seeking alcohol treatment. It also looks at early drug effects in the body to see how it might change cholesterol-related signals.
Bethesda, MarylandAges 21–65 - NCT04782830Recruiting
Wearable sensor study for low blood pressure on standing
This study uses an accelerometer (a wearable motion sensor) to measure symptoms and blood pressure changes when you stand up. It may help doctors better track how neurogenic orthostatic hypotension affects you and how well current treatments are working.
Nashville, TennesseeAges 40–80 - NCT04789850RecruitingPhase 2
Itacitinib for adults with diffuse systemic sclerosis
This Phase 2 study tests itacitinib, a targeted medicine, to see if it can safely improve diffuse systemic sclerosis (a hardening/tightening of the skin and organ involvement). You may be eligible if you have active disease or it has been present less than 3 years.
AmiensAges 18 years+ - NCT04791579RecruitingPhase 2
Preventing UTIs after Botox for neurogenic bladder
This study tests whether taking an antibiotic (ciprofloxacin) around the time of bladder Botox can prevent urinary tract infections (UTIs) in people whose bladder problems are caused by nerve conditions. It may help lower the chance of infection after treatment.
Edmonton, AlbertaAges 18–100 - NCT04794530RecruitingPhase 3
Cocoa extract trial for walking problems in blocked leg arteries
This Phase 3 study tests whether cocoa extract (cocoa flavanols) can improve walking ability and circulation in people with peripheral artery disease (PAD). It may help people who have PAD-related walking limits and can safely avoid competing cocoa sources and caffeine.
Chicago, IllinoisAges 55 years+ - NCT04797286RecruitingPhase 2
Sildenafil for early lung blood-pressure problems in scleroderma
This trial tests whether sildenafil can improve early “high pressure in the lung blood vessels” in people with scleroderma. It may help slow worsening breathing and lung blood-vessel disease before it becomes severe.
New Orleans, LouisianaAges 18 years+ - NCT04798469RecruitingPhase 2
Testosterone to reduce long-term spine pain in men on opioids
This Phase 2 study tests whether taking testosterone can lessen chronic non-cancer spinal pain in men who have low testosterone while using opioid pain medicines. It may help by improving hormone levels that could be affecting pain and overall wellbeing.
Boston, MassachusettsAges 18 years+ - NCT04804553RecruitingPhase 3
Apremilast for children with active juvenile psoriatic arthritis
This Phase 3 trial tests apremilast to treat active juvenile psoriatic arthritis (joint inflammation) in children and teens. You may be able to join if your child’s condition is active despite prior treatments or if they couldn’t tolerate them.
BregenzAges 5–17 - NCT04807894RecruitingPhase 4
Vaginal testosterone to prevent repeat UTIs in postmenopausal women
This study tests whether putting testosterone in the vagina can help prevent future bladder infections (UTIs) compared with a dummy treatment. It’s for older postmenopausal women who keep getting UTIs, especially those who can’t or don’t want to use vaginal estrogen.
Brooklyn, New YorkAges 60–90 - NCT04811313Recruiting
Tranexamic acid for children having hip bone surgery
This study tests whether tranexamic acid (a medicine that helps reduce bleeding) can safely help children during certain hip bone operations. It may help lower blood loss around the surgery.
AsyutAges 1–18 - NCT04815668Recruiting
Acupuncture for moderate-to-severe seasonal allergy rhinitis
This trial tests whether acupuncture at a specific spot behind the nose can reduce symptoms from seasonal allergies (triggered by things like grass or birch pollen). It may help if your allergy symptoms are moderate to severe and have lasted for a long time.
BeijingAges 18–75 - NCT04817618RecruitingPhase 3
Iptacopan for kidney inflammation in C3 glomerulopathy
This trial studies whether iptacopan can improve outcomes and safety for people with C3 glomerulopathy, a kidney disease caused by overactive parts of the immune system. Participants must already be on standard kidney-protecting medicines and meet specific kidney function and urine protein criteria.
Aurora, ColoradoAges 12–60 - NCT04833426RecruitingPhase 3
Testosterone levels around prostate surgery and recovery outcomes
This trial studies whether testosterone levels before and around radical prostate surgery affect cancer control and sexual/physical recovery. It may help doctors understand who benefits from testosterone replacement and who should not.
AmsterdamAges 18 years+ - NCT04844528RecruitingPhase 2
Nicotinamide for CLL patients with recent skin cancer history
This Phase 2 trial tests whether nicotinamide (a form of vitamin B3) can help people with chronic lymphocytic leukemia (CLL) who have had non-melanoma skin cancers in the past 5 years. The study looks at how well new skin cancers can be prevented or reduced.
Salt Lake City, UtahAges 18 years+ - NCT04846777Recruiting
Phone-based support program for generalized anxiety
This study tests a brief treatment approach delivered through a smartphone app (or phone-based program) for people with generalized anxiety disorder. It may help you manage anxiety while also contributing to research on easier ways to get mental health support.
University Park, PennsylvaniaAges 18 years+ - NCT04860141RecruitingPhase 4
Gabapentin before wisdom tooth removal to reduce pain
This trial tests whether taking gabapentin before extracting a wisdom tooth helps with pain and comfort after the procedure. It may help people who need a third-molar removal, if they meet the safety and health requirements.
Loma Linda, CaliforniaAges 18–59 - NCT04868578Recruiting
Vitamin PPI supplements for ectopic calcification in PXE
This trial studies whether taking PPI-type supplements can slow or reduce unwanted calcification in people with PXE. It’s meant to help manage disease changes caused by abnormal calcium deposits, based on your medical testing.
AngersAges 18–65 - NCT04869098Recruiting
Evening protein shake for night shift workers’ metabolic health
This study tests whether eating a protein preload in the evening (often called a protein “shake/meal” before sleep) can improve metabolic health in night shift workers. It aims to see if this timing and protein intake helps measures related to metabolism while working nights.
Adelaide, South AustraliaAges 35–65 - NCT04874038RecruitingPhase 3
Lidocaine infusions to prevent long-lasting pain after breast surgery
This Phase 3 study tests whether receiving lidocaine through an IV during breast surgery can lower the chance of ongoing pain afterward. If it works, it may help some people avoid chronic, surgery-related pain in the chest wall, shoulder, or arm.
Calgary, AlbertaAges 18–100
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,962 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.