Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,962 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04631471RecruitingPhase 3
Ibudilast for spinal cord pressure from neck wear
This Phase 3 study tests ibudilast, a medicine, to see if it can improve symptoms in people whose neck arthritis has started compressing the spinal cord. You would still have your usual surgery to relieve the pressure, and then take the study medicine to see if recovery and function improve.
CambridgeAges 18–80 - NCT04637438Recruiting
Fecal transplant for Crohn’s around the small and large bowel
This trial studies fecal microbiota transplantation (a transplant of beneficial gut bacteria from a donor) to help people with Crohn’s disease that is causing narrowing (strictures) and/or abnormal tunnels (fistulas) and who need bowel surgery. You may qualify if you’re an adult, planning ileal/ileocecal surgery, and can complete the colonoscopy while not on certain gut-altering medicines.
TampereAges 18–120 - NCT04637620RecruitingPhase 2
NMDA-based treatment study for major depression
This Phase 2 trial tests whether an NMDA-targeted treatment can improve symptoms of major depressive disorder (MDD). You may be able to join if your depression diagnosis and symptom score fit, and you meet several safety and study-following requirements.
TaichungAges 18–55 - NCT04643327RecruitingPhase 2
Levetiracetam study to lower dementia risk in Parkinson’s
This Phase 2 study tests whether an added medication strategy can change brain targets linked to memory decline in people with Parkinson’s disease, including those with no memory problems or mild memory changes. It may help lower risk of developing dementia, but you must be able to safely do MRI scans and meet other health and medication rules.
Brisbane, QueenslandAges Any age - NCT04646707Recruiting
Nerve block to reduce opioid use after neck spine surgery
This trial tests whether a targeted back/neck numbing injection (an erector spinae block) can help reduce the amount of opioid pain medicine needed after posterior cervical spine surgery. It also aims to support an “enhanced recovery” pathway so patients may recover more comfortably and potentially faster.
Toronto, OntarioAges 18–80 - NCT04650880Recruiting
Vitamin D study for irregular periods from PCOS
This trial studies whether taking vitamin D can improve ovulation (the release of an egg) in people with PCOS who have long, irregular menstrual cycles. It may help some participants have more regular ovulation and cycle timing, but you would be monitored with vaginal ultrasound and blood tests.
Hong KongAges 18–40 - NCT04659317RecruitingPhase 3
Opioid-free pain plan for joint and arm surgeries
This Phase 3 study tests an opioid-free approach to pain control for certain orthopedic (bone/joint) surgeries. The goal is to help people manage surgical pain without using opioid pain medicines.
Atlanta, GeorgiaAges 18 years+ - NCT04666714RecruitingPhase 3
Tested a new medicine to reduce diabetic nerve pain
This Phase 3 study tests Praga formulation to see if it safely reduces nerve pain caused by diabetes. You may qualify if you’re an adult with painful diabetic neuropathy and have certain symptom and pain scores on questionnaires.
Campinas, São PauloAges 18 years+ - NCT04670666RecruitingPhase 3
Study of Madalena for type 2 diabetes not controlled
This Phase 3 study tests Madalena to improve blood sugar control in adults with type 2 diabetes that hasn’t met targets despite diet, exercise, and diabetes medicines. You may join if your recent blood sugar tests and body size fall within specific ranges and you don’t have key medical exclusions.
Hortolândia, São PauloAges 18 years+ - NCT04678167Recruiting
Special “ring” glasses for vestibular neuritis symptoms
This trial tests whether wearing “ring” glasses helps reduce symptoms from vestibular neuritis, a condition that causes spinning vertigo and balance problems. Participants may get the glasses being tested or look-alike placebo glasses (or not wear glasses), so the study can tell if the glasses truly help.
BrestAges 18 years+ - NCT04678895RecruitingPhase 2
Low-dose naltrexone for nerve pain from diabetes
This Phase 2 trial studies whether a low dose of naltrexone can reduce painful nerve pain caused by diabetes. It may help people whose diabetic nerve pain did not improve with at least one standard treatment.
Lebanon, New HampshireAges 18 years+ - NCT04685148RecruitingPhase 1/Phase 2
Study of mental health treatment during pregnancy
This trial studies a treatment aimed at improving maternal mental health during pregnancy. It focuses on people who have had depression around pregnancy before, and checks whether the approach is safe and helpful for them.
CopenhagenAges 18–45 - NCT04703842RecruitingPhase 1/Phase 2
Study drug effect on heart muscle calcium in advanced heart failure
This trial tests a treatment intended to improve how heart muscle cells handle calcium, which may help heart failure symptoms and heart function. It is mainly for people with advanced heart failure and a low pumping strength of the heart.
San Diego, CaliforniaAges 18–80 - NCT04704271RecruitingPhase 1
Study on THC effects in people with past cannabis use
This Phase 1 study looks at how THC (the main mind-altering ingredient in cannabis) affects healthy volunteers shortly after use. It focuses on differences between people and includes those who have used cannabis before.
West Haven, ConnecticutAges 18–55 - NCT04707261RecruitingPhase 4
Testing how dapagliflozin affects anemia in heart failure
This trial studies whether dapagliflozin (a heart-failure medicine) can improve anemia in people with heart failure. It may help explain why some patients feel better and how anemia changes when this medicine is used.
Xiangtan, HunanAges 18–100 - NCT04713657RecruitingPhase 1
Beta-blocker study for heart muscle function in young babies
This trial tests whether a beta-blocker called propranolol can improve how well heart muscle cells work in very young babies with certain congenital heart conditions. It mainly looks at safety and how the medicine affects the heart, which could help guide future treatments.
New York, New YorkAges 4 weeks–2 months - NCT04722978RecruitingPhase 3
Chemo plus moxifloxacin for metastatic triple-negative breast cancer
This trial tests whether adding moxifloxacin (an antibiotic) to standard chemotherapy helps people with metastatic triple-negative breast cancer live longer or respond better. You may qualify if your cancer has the right lab markers and you haven’t had treatment for metastatic disease yet.
Guangzhou, GuangdongAges 18–70 - NCT04723862RecruitingEarly Phase 1
Spironolactone to test sleep hormone patterns in teen girls
This early-phase study tests whether spironolactone can “normalize” a key hormone timing pattern during sleep and wake cycles in mid-to-late pubertal girls who have high male-hormone levels. The goal is to learn how this medicine may affect hormone rhythms related to conditions like PCOS.
Charlottesville, VirginiaAges 10–17 - NCT04724252RecruitingPhase 2/Phase 3
Gabapentin to help children use less opioid after surgery
This study tests whether gabapentin can reduce how much opioid pain medicine children need after certain major chest or heart surgeries. If it works, it may lower opioid-related side effects while still helping with postoperative pain.
Sacramento, CaliforniaAges Up to 17 years - NCT04741646RecruitingPhase 2
Ferric citrate for kids with chronic kidney disease
This Phase 2 study tests ferric citrate, a medicine that helps control phosphate and iron balance, in children with chronic kidney disease. It may help slow problems related to kidney disease by improving lab measures like phosphate levels.
Los Angeles, CaliforniaAges 6–18 - NCT04745143RecruitingPhase 2
NMDA-enhancer medicine tested for schizophrenia without antipsychotics
This Phase 2 trial tests a single medicine intended to help people with schizophrenia who cannot take standard antipsychotic medications due to side effects or poor response. It may help reduce schizophrenia symptoms, but whether you can join depends on your diagnosis, medication history, and health conditions.
TaichungAges 18–65 - NCT04748601RecruitingPhase 4
Qudexy XR to help prevent migraine in kids ages 6 to 11
This study tests whether Qudexy XR can reduce migraine headaches in children ages 6 to 11. It looks for kids who are having frequent, disruptive migraine attacks and checks safety with careful medication rules.
Birmingham, AlabamaAges 6–11 - NCT04750616RecruitingPhase 2
NAD+ for heart injury prevention around non-emergency surgery
This Phase 2 trial studies whether adding NAD+ can reduce heart muscle injury around scheduled heart surgery. It may help protect the heart (and possibly kidneys) in people considered higher risk for complications.
San Francisco, CaliforniaAges 18 years+ - NCT04759001RecruitingPhase 1/Phase 2
Fecal treatment to clear gut bacteria resistant to antibiotics
This study tests a stool-based treatment (fecal microbiota treatment) to help remove “carbapenem-resistant” bacteria living in the gut. If you carry these bacteria without being sick, the goal is to reduce or stop that colonization.
RomeAges 18–90
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,962 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.