Placebo Effect clinical trials

Study of tirzepatide for alcohol use disorder

This trial tests if tirzepatide, a diabetes drug, affects brain chemistry linked to alcohol use. Researchers want to see if it can help people with mild-to-moderate alcohol use disorder who also have tried stimulants.

Testing a new medicine in healthy volunteers

This study tests a new experimental medication (QX-4533) in healthy volunteers to find the best dose and see how it works in the body. It involves taking the medication and having your health monitored closely over time.

Diacerein to improve knee osteoarthritis symptoms

This Phase 3 study tests diacerein (Artrodar®) to see if it can improve symptoms in people with knee osteoarthritis, and it uses movement and scan-based assessments. It may help reduce walking pain and improve knee function for the right patient group.

Test supplements to change how sugars attach to blood proteins

This early (Phase 1) study tests how adding specific dietary supplements affects “protein glycosylation,” which means how sugar molecules attach to proteins in your blood. It’s meant to see how the supplements change these blood measurements and whether the approach is tolerable in generally healthy adults.

Cannabidiol trial for learning and anxiety

This early-phase study tests how cannabidiol (CBD) affects learning and anxiety. You may be able to join if you meet age and health requirements and have not used CBD or other cannabis recently.

THC study for blood sugar control in type 2 diabetes

This early-phase study tests how THC (the main cannabis ingredient) affects blood sugar levels in people with type 2 diabetes. It may help researchers understand whether THC changes glucose control and what risks come with it.

Ketamine study for OCD after prior treatment failed

This Phase 2 study tests how ketamine may work quickly in people with obsessive-compulsive disorder (OCD), especially after at least one standard treatment didn’t help. If you join, you’ll need to follow study procedures like fasting before the experimental visit and not enrolling in other medication trials during the study.

Comparing treatments for acute sinusitis

This trial tests whether nasal steroids, nasal irrigation, or oral antibiotics work best for acute sinusitis. It may help if you have ongoing sinus symptoms or a 'double-sickening' pattern after a cold.

THC and d-limonene for cannabis anxiety

This study tests if a natural compound called d-limonene (found in citrus oils) can reduce anxiety that some people feel after using high-THC cannabis. You'll receive THC and d-limonene in capsules under medical supervision.

Antioxidant supplement for blood vessel health

This study tests whether an antioxidant supplement can improve blood vessel health in healthy adults. It compares the supplement's effects in non-Hispanic Black and non-Hispanic White participants to see if there are differences in how blood vessels respond.

Light therapy for patients on breathing machines

This study tests a light therapy (called PBMT-sMF) on people in the ICU who need a breathing machine. It aims to see if the treatment helps muscles and recovery.

Shengbai oral formula for chemotherapy side effects

This study tests if a Chinese herbal formula called Shengbai can safely reduce side effects from chemotherapy. It might help you feel better during cancer treatment.

Colchicine for CPPD: reducing pain and inflammation

This trial tests if colchicine can reduce pain and swelling in people with CPPD (calcium pyrophosphate deposition disease), a type of arthritis. If you have had a swollen, red, or warm joint in the last 3 months and your pain is moderate or higher, this study may offer a possible treatment.

Testing Fertitonex for varicocele and infertility

This study tests if a medicine called Fertitonex can improve sperm quality in men who have varicocele (enlarged veins in the scrotum) and are having trouble getting their partner pregnant for the first time.

Melatonin for heart muscle protection

This trial tests if adding melatonin to standard heart medication helps protect the heart muscle in people with cardiomyopathy. If you are stable on your current heart meds, you may be able to join.

Pectin supplement for frailty in older adults

This study tests if daily pectin, a fiber found in fruits, can improve strength and health in older adults who are frail or pre-frail. It compares pectin to a placebo over time.

Nutritional effects in heart surgery

This trial looks at whether adding a probiotic supplement before cardiovascular surgery can improve recovery. It studies the link between nutrition, gut health, and surgical outcomes.

Testing a new drug's safety in healthy adults

This trial tests a new medicine called LY03021 in healthy volunteers to see how safe it is, how the body processes it, and if food changes its effects. It's for people who are generally healthy and not taking other medications.

Diagonal Mobilization Effects in Young Soccer Players

This study looks at how a treatment called diagonal mobilization affects teenagers who play soccer. It checks if this approach helps lower the chance of injury.

Probiotics for colds in young children

This trial tests whether taking probiotics can help young children recover faster from common colds. If your child has a mild or moderate cold and is not taking other probiotics, they may be able to join.

Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease

Alendronate for knee recovery after ACL surgery

This trial tests whether alendronate, a drug commonly used for bone health, can improve knee function and recovery after ACL surgery. It is for people having their first ACL repair.

A drug trial for adults with Graves' disease

This trial is testing a new drug, BHV-1300, to see if it works and is safe for people with Graves' disease. It might be an option if you have active hyperthyroidism (overactive thyroid) caused by Graves' disease and haven't had certain other treatments.

Postbiotic Supplement Study for Female Athletes

This study tests whether a postbiotic supplement (a type of gut health product) can reduce digestive problems that female athletes experience during exercise and their menstrual cycle. You'll take the supplement for several months while tracking your symptoms and training.