Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,225 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04218409RecruitingEarly Phase 1
Tests a spray to reduce opioid use and pain
This early trial studies whether Syntocinon can lower pain and help reduce how much opioids people use. It checks safety and the best dose by giving participants the study drug under close medical monitoring.
Gainesville, FloridaAges 21–45 - NCT04257487RecruitingPhase 3
Sulodexide to prevent blood clots from coming back
This study tests sulodexide (a blood-vessel protective medicine) to help stop deep leg blood clots or lung clots from returning after you’ve already been treated. It may help people with higher bleeding risk who are taking or recently finished standard anticoagulant medicines.
RozzanoAges 75 years+ - NCT04302870RecruitingPhase 2/Phase 3
Test medicines for motor neurone disease using adaptive trial design
This study tests treatments for motor neurone disease (MND) and assigns people to different treatment arms in an adaptive way. It may help doctors find out which medicine works best and for whom.
Portadown, County ArmaghAges 18 years+ - NCT04374799RecruitingPhase 3
Heparin vs placebo during cardiac catheterization
This trial tests whether giving heparin (a blood thinner) during a specific type of heart procedure is safer and works better than not giving it. It focuses on patients where the blood supply in the hand’s artery connection is functioning properly.
Hamilton, OntarioAges 18 years+ - NCT04448028RecruitingPhase 4
Stopping acid pills in liver cirrhosis: test placebo effect
This study tests whether stopping proton-pump inhibitor (PPI) acid-reducing medication is safe and works as expected for people with liver cirrhosis. Participants switch to either the study medication or a placebo (inactive pill) under close monitoring.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT04591990RecruitingPhase 3
Hydrocortisone and vasopressin for shock after cardiac arrest
This Phase 3 trial tests whether hydrocortisone plus vasopressin (or related hormone treatments) can improve shock in adults after a resuscitated cardiac arrest. It targets people who remain very low in blood pressure despite fluids and need strong IV medicines to maintain blood pressure.
AmiensAges 18 years+ - NCT04629144RecruitingPhase 2
Belimumab for active cryoglobulinemia vasculitis after rituximab
This Phase 2 study tests belimumab (or a placebo) to see if it improves safety and disease control in adults with active cryoglobulinemia vasculitis. You may be eligible if you have had rituximab induction treatment shortly before joining, and your illness is still active.
BloisAges 18 years+ - NCT04654988RecruitingPhase 4
Immunosuppression study for active myocarditis or inflammatory cardiomyopathy
This Phase 4 study tests whether weakening the immune system (immunosuppression) works better for people with active myocarditis or inflammatory cardiomyopathy. It includes extra heart tests—two heart muscle biopsies and two heart MRI scans—to confirm the diagnosis and guide treatment.
WarsawAges 18–65 - NCT04807894RecruitingPhase 4
Vaginal testosterone to prevent repeat UTIs in postmenopausal women
This study tests whether putting testosterone in the vagina can help prevent future bladder infections (UTIs) compared with a dummy treatment. It’s for older postmenopausal women who keep getting UTIs, especially those who can’t or don’t want to use vaginal estrogen.
Brooklyn, New YorkAges 60–90 - NCT04901273Recruiting
PRP shot vs placebo for knee osteoarthritis in adults 65+
This trial compares an injection made from your own platelets (PRP) to a placebo shot to see if it helps knee osteoarthritis symptoms and function. It is designed for people over 65 with arthritis affecting only one knee.
BolognaAges 65 years+ - NCT07699601RecruitingPhase 2/Phase 3
Testing a pain tablet after orthopedic surgery
This trial tests an investigational tablet called HL-1186 for controlling pain after orthopedic surgery. It explores whether the drug can safely reduce moderate to severe pain when given after the procedure.
Changsha, HunanAges 18–75 - NCT07266831RecruitingPhase 2/Phase 3
Study of islatravir and ulonivirine for new HIV patients
This trial tests two new HIV medications, islatravir and ulonivirine, in people who have never taken HIV treatment before. It aims to see if this combination can safely control the virus.
Los Angeles, CaliforniaAges 18 years+ - NCT07051655Recruiting
Ketone drink for thinking and memory
This study tests whether a drink containing ketones (a natural energy source for the brain) can improve thinking and memory. It involves three groups: people with obesity, lean people, and athletes.
Birmingham, AlabamaAges 19–55 - NCT06742996RecruitingPhase 3
Sonrotoclax plus zanubrutinib for relapsed mantle cell lymphoma
This trial tests a new combination of two targeted therapies for people with mantle cell lymphoma that has come back or hasn't responded to prior treatment. It aims to see if adding sonrotoclax to zanubrutinib works better than zanubrutinib alone.
Birmingham, AlabamaAges 18 years+ - NCT04974138RecruitingPhase 4
Preventing first stroke in people with high-risk blood pressure
This trial tests whether a study medicine regimen can help prevent a first stroke in people with hard-to-control “high homocysteine” risk factors linked to a specific gene type. You may qualify if you have certain blood pressure levels, a specific MTHFR gene result, and related blood test findings.
Bengbu, AnhuiAges 45–74 - NCT04996017RecruitingPhase 3
Atezolizumab after surgery for malignant pleural mesothelioma
This study tests whether atezolizumab given after surgery and chemotherapy can lower the risk of mesothelioma coming back compared with a placebo. It may help by boosting the immune system to control remaining microscopic cancer cells.
Meldola, ITAòYAges 18 years+ - NCT04998188Recruiting
Hydrolyzed collagen for one knee with osteoarthritis
This trial tests whether a hydrolyzed collagen drink or supplement can reduce knee pain and symptoms compared with a placebo (inactive treatment) in people with osteoarthritis. It may help if you’ve tried standard non-surgical treatments and still have ongoing knee trouble.
BolognaAges 18–75 - NCT05016219Recruiting
Light therapy to improve sleep and thinking in early Alzheimer’s
This trial studies rhythmic light therapy to help people with early Alzheimer’s or mild memory problems, especially when sleep is getting worse. If you fit the sleep and vision/medical safety requirements, the study may see whether the therapy improves sleep and thinking-related symptoms.
Menands, New YorkAges 55 years+ - NCT05028829RecruitingPhase 2
Atorvastatin to lower liver cancer risk in people with liver scarring
This trial tests whether atorvastatin (a cholesterol medicine) can lower the chance of liver cancer (HCC) in people with advanced liver scarring or cirrhosis. Participants are compared to placebo (inactive pill) while researchers track safety and cancer risk.
Boston, MassachusettsAges 18 years+ - NCT05110144RecruitingPhase 2
Testing two doses of two nerve pain medicines for chronic cough
This Phase 2 study tests whether two doses of duloxetine and amitriptyline can reduce symptoms in people with chronic cough that hasn’t responded to usual care. You may join to see if these medicines lessen cough severity over an 8-week blinded treatment period.
Rochester, MinnesotaAges 18–75 - NCT05120934RecruitingPhase 2
Two medicine doses to reduce ILD cough
This Phase 2 study tests whether two different doses of duloxetine and amitriptyline can reduce coughing caused by interstitial lung disease (ILD). If you have had a long-lasting ILD-related cough despite stable ILD treatment, this trial may help find a better way to control your cough.
Rochester, MinnesotaAges 18–75 - NCT05193396RecruitingPhase 4
Hydrocortisone trial for adrenal symptoms after stopping steroid pills
This trial tests whether hydrocortisone (a cortisol replacement) helps people who feel symptoms of adrenal insufficiency after they stop long-term prednisolone. It compares hydrocortisone versus placebo to see if symptoms improve and dosing is safer/effective.
AarhusAges 50 years+ - NCT05268289RecruitingPhase 2
Trial for lupus kidney inflammation using LNP023
This Phase 2 study tests whether LNP023 can improve outcomes and safety in people with active lupus nephritis (lupus-related kidney inflammation), class III or IV. It may help by targeting the ongoing immune activity that is damaging the kidneys.
Phoenix, ArizonaAges 18–100 - NCT05269628RecruitingPhase 2
Cannabidiol for multiple sclerosis sleep and pain patterns
This study looks at whether cannabidiol (CBD, a cannabis-related medicine) can improve symptoms in people with multiple sclerosis (MS), especially how sleep and pain type affect outcomes. It’s mainly for people with MS and ongoing moderate-to-severe pain, while carefully checking safety and medication interactions.
Ann Arbor, MichiganAges 18–65
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,225 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.