Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,154 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03866408RecruitingEarly Phase 1
Testing how insulin affects fat breakdown proteins
This early study looks at how insulin changes the body’s fat breakdown and related proteins. You might join if you’re within a certain body-weight range and can safely take the study medication.
Rochester, MinnesotaAges 18–55 - NCT03783416RecruitingPhase 1
Ixazomib safety study for people with multiple sclerosis
This early-phase study tests how safe ixazomib is for people with multiple sclerosis (MS). It focuses on targeting certain immune cells in MS and checks whether the treatment can be given safely.
London, Greater LondonAges 18–65 - NCT03794076RecruitingPhase 1/Phase 2
Testing adjunct cromoglicate for schizophrenia symptoms
This trial studies whether adding cromoglicate to your usual antipsychotic medicine can improve schizophrenia symptoms. It’s designed for outpatients who are already on a stable treatment and still have certain ongoing symptom scores.
Pittsburgh, PennsylvaniaAges 18–65 - NCT03860233RecruitingPhase 1
Oxytocin added to CPAP for obstructive sleep apnea
This early study tests whether adding oxytocin to your usual CPAP treatment improves obstructive sleep apnea. It may help see if oxytocin changes how well CPAP works or how people feel while using it.
Washington D.C., District of ColumbiaAges 18 years+ - NCT03734900RecruitingPhase 4
Comparing two knee injection treatments for osteoarthritis
This study compares two knee injection treatments for knee osteoarthritis. It aims to see which one works better for reducing pain and improving function, so you might experience less knee pain and better mobility.
TaipeiAges 50–80 - NCT03875378RecruitingPhase 2
Transdermal estrogen treatment for anorexia-related bone loss
This trial studies whether estrogen delivered through the skin can help improve bone health in women with anorexia nervosa. It may be considered if your body weight is low and you have signs of bone thinning.
Pittsburgh, PennsylvaniaAges 19–45 - NCT03673748RecruitingPhase 2
Mesenchymal stem cell treatment for lupus kidney inflammation
This trial tests whether donated (allogeneic) stem cells can improve lupus nephritis, a kidney complication of lupus. It is for adults whose lupus kidney disease has not responded well to standard treatments or has come back, and it requires signs of active disease.
Valladolid, ValladolidAges 18 years+ - NCT03695887RecruitingEarly Phase 1
Disposable nitrous oxide for pain during burn dressing changes
This early-stage study tests whether using disposable nitrous oxide canisters can better control pain when you need burn dressing changes. It may help by making dressing changes more comfortable, but eligibility depends on your burn size, health, and breathing ability.
Winnipeg, ManitobaAges 18 years+ - NCT03675724Enrolling by invitationPhase 2
Fisetin for frailty and inflammation in older adults
This trial studies whether fisetin, a supplement-like drug, can reduce frailty and inflammation in people age 70 and older. It may help improve health measures related to aging, but you must meet several safety and medication rules to join.
Rochester, MinnesotaAges 70 years+ - NCT03593317RecruitingPhase 2
Test medicine that blocks hormones for ARVD heart disease
This Phase 2 trial studies whether blocking certain heart/hormone signals can improve ARVD (a heart muscle condition). It also looks at safety by checking how well your kidneys and electrolytes tolerate these medicines.
AmiensAges 18 years+ - NCT03540758RecruitingPhase 2
Study of how brain sugar control channels affect blood sugar
This Phase 2 study tests how certain channels in the brain help control how your body makes and releases sugar (glucose). It may help explain blood sugar problems in people with type 2 diabetes and healthy volunteers.
The Bronx, New YorkAges 21–70 - NCT03621553RecruitingPhase 4
Vitamin D balance study in people with sarcoidosis
This Phase 4 study looks at how your body keeps vitamin D levels balanced in sarcoidosis. It may help researchers understand what affects calcium and vitamin D in sarcoidosis, and guide safer care.
Dallas, TexasAges 21 years+ - NCT03553186RecruitingPhase 3
Tranexamic acid to reduce bleeding in spine surgery
This Phase 3 trial tests whether tranexamic acid can reduce bleeding during major spine fusion surgery for adults with scoliosis or spine degeneration. It may help lessen blood loss and the need for transfusions, while monitoring safety.
New York, New YorkAges 18–80 - NCT03552705RecruitingPhase 2
Tranexamic acid to reduce knee inflammation after ACL injury
This Phase 2 study tests whether tranexamic acid can reduce swelling and protect knee cartilage after an ACL injury. It may help by limiting bleeding-related inflammation in the injured joint soon after injury.
Stanford, CaliforniaAges 18–30 - NCT03543839RecruitingPhase 4
Belimumab for early lupus activity in the first two years
This trial tests belimumab to see if it can improve lupus (SLE) disease activity in people who were diagnosed within the last two years. You may be eligible if your lupus is currently mild to moderate and your background lupus medicines are stable.
Manhasset, New YorkAges 18 years+ - NCT03406611RecruitingPhase 1/Phase 2
Enzyme replacement for classical homocystinuria in children
This study tests a new enzyme replacement therapy called pegtibatinase for children with classical homocystinuria (HCU). The enzyme helps break down homocysteine, which may lower its levels in the blood and reduce symptoms.
Aurora, ColoradoAges 5–65 - NCT03407079RecruitingPhase 2
Study of sucralose’s effects on digestion of drugs
This study tests whether the sugar substitute sucralose changes how your body absorbs and breaks down certain medicines. You’d take sucralose or a placebo for 4 weeks, visit the clinic, and complete required samples and medicine doses during visits.
Bethesda, MarylandAges 18–60 - NCT03418038RecruitingPhase 2
Vitamin C with chemotherapy for lymphoma and blood disorders
This trial tests whether adding high-dose vitamin C (ascorbic acid) to standard chemotherapy helps treat lymphomas that have come back or not responded, as well as two related blood disorders (CCUS and CMML). The goal is to see if the vitamin C makes the chemo work better.
Mankato, MinnesotaAges 18 years+ - NCT03438526RecruitingPhase 4
Melatonin treatment for low-activity delirium in ICU patients
This trial tests whether giving melatonin (or a placebo) can help adults in the intensive care unit who have a specific type of confusion called low-activity delirium. It aims to improve recovery by supporting sleep–wake regulation in the ICU.
BaselAges 55 years+ - NCT03338387Enrolling by invitationPhase 2
Test effects of gut hormones in bulimia
This trial studies how growth-related and gut hormones affect ghrelin, a hunger-related hormone, in people with bulimia. It may help researchers understand the body changes behind bulimia and how hormones and appetite signals work.
Ages 18–30 - NCT03368092RecruitingPhase 3
Inhaled medication to prevent lung failure after severe trauma
This trial tests whether inhaled dornase alfa can reduce the risk of respiratory (lung) failure in adults with severe trauma who are on a breathing machine in the ICU. If it works, it may help patients spend less time with dangerous breathing complications.
StrasbourgAges 18 years+ - NCT03430037Enrolling by invitationPhase 2
Fisetin study to reduce frailty and inflammation in older women
This Phase 2 trial tests whether fisetin, a supplement, can reduce frailty and inflammation in postmenopausal women age 70 and older. If it works, it may help older adults feel stronger and have healthier body signals related to aging and inflammation.
Rochester, MinnesotaAges 70 years+ - NCT03370224Enrolling by invitation
Story memory training for older adults
This study tests a memory-skills training approach (the Modified Story Memory Technique) to help older adults with aging-related memory changes. You may be asked to do memory exercises, and some people may also complete an optional brain MRI scan.
East Hanover, New JerseyAges 65 years+ - NCT03065335RecruitingPhase 1
Ketamine plus brain imaging to study response in depression
This early-stage study tests how ketamine given once and then repeatedly may change brain signals and related biomarkers in people with major depression. If you’re eligible, the team will use brain imaging and assessments to see who responds and why.
Bethesda, MarylandAges 18–65
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,154 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.