Clinical trials
Plaque clinical trials
Below are recruiting plaque clinical trials, each written for real people, not researchers. We’re tracking 181 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07362017RecruitingPhase 3
Ponesimod for moderate to severe plaque psoriasis
This trial tests an investigational drug called ponesimod for people with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective at improving skin symptoms.
Glendale, ArizonaAges 18–65 - NCT07414173RecruitingPhase 4
Mouthrinse for plaque and gum health
This study tests whether a special antimicrobial mouthrinse can reduce plaque buildup and improve gum health over 6 months. If you have early gum disease (gingivitis) and are generally healthy, this trial may be a good fit.
SchenefeldAges 18–70 - NCT07470528Recruiting
Comparing two surgeries for complex Peyronie's disease
This trial compares two surgical techniques to correct severe penile curvature caused by Peyronie's disease. It tests which approach works better for men with advanced or complex cases.
Tekirdağ, TekirdağAges 18 years+ - NCT07555223Recruiting
Using 3D Scans to Better Detect Tooth Decay
This study tests whether special 3D imaging and intraoral scanning tools can help dentists better identify tooth decay and plaque buildup. Researchers want to see if these new methods work well and could improve how cavities are diagnosed.
Wondelgem, BotestraatAges 18–70 - NCT07611942Recruiting
Plaque Removal in Children With Learning Disabilities
This study compares how well children with learning disabilities can remove plaque from their teeth compared to children without learning disabilities. It aims to understand if dental plaque removal is harder for children with specific learning challenges.
Alanya, AntalyaAges 7–12 - NCT07614490RecruitingPhase 4
Dental plaque and gum health study
This research study examines how dental plaque relates to gum inflammation in people with different levels of gum health. Researchers will collect plaque samples and measure gum health to better understand these patterns, which may help improve oral care products.
Fort Wayne, IndianaAges 18 years+ - NCT07619014Recruiting
Miswak vs. toothbrush for cleaning teeth with braces
This study compares how well a miswak (a natural chewing stick) and a regular toothbrush remove plaque buildup around orthodontic braces. If you wear braces, this trial tests whether miswak might be an equally effective cleaning option.
HomsAges 18–30 - NCT07050134Enrolling by invitation
Study of DR10624 for high triglycerides and carotid artery plaque
This trial tests a new drug, DR10624, to see if it can lower high triglycerides and reduce plaque in the carotid artery (the main artery in your neck). It may help people with both conditions who are also overweight.
Hefei, AnhuiAges 18–65 - NCT07704905Recruiting
Study on a new toothpaste with stannous fluoride for gum health
This trial tests a new toothpaste containing stannous fluoride to see if it improves gum health. If you have mild gum issues but are otherwise healthy, this study might be a good fit.
Fort Wayne, IndianaAges 18 years+ - NCT07535008Recruiting
Dental Cleaning to Prevent Graft-Versus-Host Disease
This study tests whether professional dental cleaning after a stem cell transplant can help prevent chronic graft-versus-host disease (GVHD), a condition where transplanted immune cells attack your body. You'll receive dental cleanings and be followed for one year to see if this simple preventive step reduces GVHD complications.
Seattle, WashingtonAges 18 years+ - NCT05122897Recruiting
Study of plaque biofilm on temporary implant crown rings
This study looks at how plaque-biofilm (a thin layer of germs that can stick to surfaces) forms on temporary parts of dental implant crowns. If you have dental implants and are healthy and stable with gum health, your care team may use specific temporary rings to study biofilm buildup.
BaselAges 18 years+ - NCT06017817Recruiting
Light therapy for implant gum disease
This study tests a special light-activated treatment (antibacterial photodynamic therapy) to fight infection around dental implants. It may be an option for people with moderate to severe implant-related gum disease who are not smokers and do not have diabetes.
StockholmAges 18–85 - NCT06508697Recruiting
Heart Plaque on CT and Events After Avoiding Stenting
This study looks at how features of plaque (fatty buildup) in the heart arteries, seen on a CT scan, relate to future heart events in people who decided not to have a stent placed based on a special blood flow test (FFR). It may help doctors better understand when it's safe to avoid stenting.
Toyoake, Aichi-kenAges 20 years+ - NCT06404242Recruiting
Plaque features predict repeat stroke after middle cerebral artery blockage
This study looks at people who recently had a stroke caused by hardening of the arteries in the middle cerebral artery, a major blood vessel in the brain. The researchers use special MRI scans to see if the plaque (the fatty buildup) can predict whether another stroke might happen.
Ho Chi Minh City, Ho Chi Minh CityAges 45–100 - NCT05724836Recruiting
Carotid artery narrowing treatment follow-up at clinic
This study follows people who are getting a procedure for carotid artery narrowing at the clinic. It aims to learn about outcomes after these treatments.
Jacksonville, FloridaAges 18 years+ - NCT07683065Recruiting
Secukinumab treatment in psoriasis patients with liver condition
This study looks at how well secukinumab works for psoriasis patients who also have a type of fatty liver disease called MASLD. It may help doctors understand if this treatment is a good option for people with both conditions.
Badalona, BarcelonaAges 18–100 - NCT07116967RecruitingPhase 3
Long-term safety of two psoriasis drugs in people with heart risk
This study compares two medications for psoriasis (deucravacitinib and ustekinumab) over a long period. It's designed for people with moderate-to-severe psoriasis who also have certain risk factors for heart disease, like high blood pressure or diabetes.
Birmingham, AlabamaAges 40 years+ - NCT07511647RecruitingPhase 3
Study of QL2106 for moderate to severe plaque psoriasis
This trial tests an injectable drug, QL2106, for people with moderate to severe plaque psoriasis. It may help if you are a candidate for light therapy or other systemic treatments.
Jining, ShandongAges 18 years+ - NCT07693972Recruiting
Probiotic vs zinc mouthwash for bad breath and plaque in braces
This trial compares a probiotic mouthwash to a zinc and chlorhexidine mouthwash to see which is better at controlling bad breath and plaque for people with braces. It aims to find a gentler option that still works well.
Baghdad, AlkarghAges 18–30 - NCT06896708Recruiting
Intensive cholesterol treatment for heart plaque in younger adults
This trial tests whether higher doses of cholesterol-lowering medication (statins) can slow down plaque buildup in the heart arteries of younger and middle-aged adults with stable chest pain. It may help prevent heart attacks and the need for procedures like stents.
Chongqing, Chongqing MunicipalityAges 18–60 - NCT04036188RecruitingEarly Phase 1
Vitamin D and triamcinolone for plaque psoriasis
This early study tests whether taking vitamin D together with triamcinolone (a steroid used on skin) works better for plaque psoriasis than a standard approach. It aims to see if the combination helps clear psoriasis plaques and is safe.
Fairborn, OhioAges 18 years+ - NCT06789458Recruiting
Pro-resolution mediators in severe gum disease before and after treatment
This study looks at natural substances in your blood that help reduce gum inflammation. Researchers want to see how these substances change after standard gum disease treatment, which may lead to better ways to manage severe periodontitis.
Manial, Cairo GovernorateAges 18–80 - NCT06912165RecruitingPhase 2
WD-890 for moderate to severe plaque psoriasis
This study tests an investigational drug called WD-890 for people with moderate-to-severe plaque psoriasis that hasn't responded well enough to other treatments. It may help reduce skin patches, scaling, and itching.
Nanjing, JiangsuAges 18–70 - NCT07183111Recruiting
AI vs. regular instructions for braces patients
This trial compares standard instructions to AI-powered guidance (using a custom ChatGPT) to help patients with braces learn how to care for their teeth. It aims to see which method helps patients follow oral hygiene instructions better.
Islamabad, FederalAges 18–30
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Common questions
- Are there clinical trials for plaque?
- Yes. Clin2 currently lists 181 recruiting plaque studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a plaque trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a plaque trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.