Clinical trials
Plaque clinical trials
Below are recruiting plaque clinical trials, each written for real people, not researchers. We’re tracking 179 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07039110Recruiting
Risankizumab for psoriasis: quality of life study
This study looks at how risankizumab (Skyrizi) affects the quality of life for adults with moderate-to-severe plaque psoriasis. It is an observational study, meaning no new treatments are given—researchers simply follow patients who are already being treated with risankizumab as part of their regular care.
Calgary, AlbertaAges 18 years+ - NCT06984744Recruiting
Gum health study testing a new compound
This study tests a compound in gum to see how well it prevents plaque buildup over 4 days. You may be able to join if you are a healthy adult with at least 20 natural teeth and some existing plaque.
Indianapolis, IndianaAges 18–65 - NCT06979453RecruitingPhase 3
A study of deucravacitinib for teens with plaque psoriasis
This trial tests an investigational oral medication called deucravacitinib for teenagers (adolescents) with moderate to severe plaque psoriasis. It aims to see if the drug is safe and works well.
Birmingham, AlabamaAges 12–17 - NCT06511830Recruiting
Comparing plaque detection methods for better dental care
This study compares different ways of checking dental plaque (the sticky film on teeth) to see which method works best. It may help you understand how to better care for your teeth and gums.
Lincoln, NebraskaAges 19–85 - NCT06842199RecruitingPhase 3
Testing a new pill for moderate to severe plaque psoriasis
This trial tests an experimental drug called ICP-488 for people with moderate to severe plaque psoriasis. It aims to see if the drug can improve symptoms and is safe, and may be an option if you need stronger treatment than creams or light therapy.
Hefei, AnhuiAges 18–75 - NCT06603363Recruiting
Statin effects on heart artery plaques seen on CT scans
This trial studies how short-term statin therapy changes plaque buildup in heart arteries. It uses CT scans to see if statins can make plaques more stable and reduce heart risks.
Budapest, BudapestAges 45–75 - NCT05764772Recruiting
Testing features of plaque in symptomatic carotid narrowing
This study looks at the makeup of plaque in the carotid artery (the neck blood vessel to the brain) in people who recently had a stroke caused by that narrowing. Researchers will use MRI and planned surgery to see which plaque components may matter for stroke risk and outcomes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05821894Recruiting
Imaging study of plaque in neck arteries before surgery
This study uses pictures (imaging) to learn more about plaque in the neck arteries in people who are being considered for carotid endarterectomy. The results may help doctors better understand artery plaque and improve care.
Malmö, Skåne CountyAges 18 years+ - NCT04772079RecruitingPhase 3
Test drug safety and effectiveness for youth plaque psoriasis
This study checks whether deucravacitinib works well and is safe in children and teens with moderate to severe plaque psoriasis. It also looks at drug levels in the body to help understand how the treatment behaves over time.
Ciudad Autonoma de Buenos Aires, Buenos AiresAges 4–18 - NCT07877480Recruiting
Predicting high-risk carotid plaque with imaging and biomechanics
This study looks at using scans and computer models to better predict which carotid artery plaques are dangerous, which may help guide safer treatment decisions.
MilanAges 18 years+ - NCT07683065Recruiting
Secukinumab treatment in psoriasis patients with liver condition
This study looks at how well secukinumab works for psoriasis patients who also have a type of fatty liver disease called MASLD. It may help doctors understand if this treatment is a good option for people with both conditions.
Badalona, BarcelonaAges 18–100 - NCT03827876RecruitingPhase 4
Enstilar added to Enbrel or Humira for plaque psoriasis
This trial tests whether adding Enstilar (a skin spray/foam medication) on top of your usual injection—Enbrel or Humira—works better for plaque psoriasis. You might be a candidate if your psoriasis affects a moderate amount of skin and you’ve been on Enbrel or Humira long enough.
East Windsor, New JerseyAges 18 years+ - NCT04347473RecruitingPhase 4
ILUMYA plus halobetasol ointment for plaque psoriasis
This trial studies whether ILUMYA (an injection) working together with halobetasol ointment helps control moderate-to-severe plaque psoriasis. It is meant for adults whose psoriasis is significant enough that they may need light therapy (phototherapy) and/or pills/injections (systemic therapy).
East Windsor, New JerseyAges 18 years+ - NCT05509010Recruiting
AI registry using CT scan to assess coronary artery disease
This trial builds and tests an AI system using information from a heart CT scan to help evaluate coronary artery disease (clogged heart arteries). If you need a CT coronary angiography for medical reasons, this may help improve how such scans are analyzed and used in care.
SingaporeAges 21–80 - NCT05550077Recruiting
Imaging study for narrowed brain arteries after stroke
This trial uses a detailed eye/brain imaging test (optical coherence tomography) to study people with significantly narrowed brain arteries after certain stroke-like events. It may help researchers better understand and monitor this condition to improve care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05156736Recruiting
Study of early heart artery disease in South Asians
This study looks at early buildup of plaque in heart arteries in young adults from Pakistan. It may help doctors understand why this happens earlier and guide better prevention and screening.
Karachi, SindhAges 35–65 - NCT05681858Recruiting
Testing heart inflammation and reduced blood flow in MINOCA
This study looks at why some people have chest pain and heart injury signs, but their heart arteries are not blocked. It tests scans of blood flow and heart tissue to better understand the cause and guide care.
BergenAges 18 years+ - NCT07864051Recruiting
Studying blood flow to predict plaque growth in heart arteries
This trial uses special imaging to look at how blood flows through the heart's arteries. It aims to see if certain blood flow patterns can predict where harmful plaque (fatty buildups) may grow, which could help prevent future heart problems.
LondonAges 40 years+ - NCT07864025Recruiting
Better imaging for heart artery blockages in stable angina
This study uses advanced imaging techniques to look at the build-up inside heart arteries in people with stable angina. It aims to help doctors understand and treat these blockages more accurately.
LondonAges 18–79 - NCT06365502Recruiting
Preventing future heart attacks with drug-coated balloon
This trial tests whether a balloon coated with medicine (drug-coated balloon) can prevent future heart attacks by treating high-risk plaques in arteries that are not the one that caused your current heart attack. You may qualify if you already had a stent placed and have another mildly blocked artery with certain vulnerable features.
Beijin, Beijing MunicipalityAges 18–80 - NCT07842042Recruiting
Toothpaste study for gum health
This study tests a toothpaste with stannous fluoride to see how it affects gum health by measuring certain markers in the fluid around the teeth. It may help reduce gum inflammation and improve oral hygiene.
BirminghamAges 18–70 - NCT05744466Recruiting
Compare two psoriasis medicines using real-world patient data
This study looks at how well two common plaque psoriasis medicines—deucravacitinib and apremilast—work in everyday care. It may help researchers understand which option performs better in real patients outside of a traditional drug trial.
Waltham, MassachusettsAges 18 years+ - NCT07787169RecruitingPhase 1
Study of amyloid-targeting therapies for Alzheimer's disease
This study tests several new experimental medications that target amyloid plaques, the protein clumps linked to Alzheimer's disease. It aims to find out if these treatments are safe and well-tolerated in people with early-stage Alzheimer's and in healthy volunteers.
Anaheim, CaliforniaAges 18–85 - NCT07780929Recruiting
Study of XJH05 ointment for mild-to-moderate plaque psoriasis
This trial tests a new ointment (XJH05) for people with mild-to-moderate plaque psoriasis. It aims to see if this treatment helps reduce symptoms and is safe for topical use.
Xi'an, ShaanxiAges 18–65
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Common questions
- Are there clinical trials for plaque?
- Yes. Clin2 currently lists 179 recruiting plaque studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a plaque trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a plaque trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.