Clinical trials
Plaque clinical trials
Below are recruiting plaque clinical trials, each written for real people, not researchers. We’re tracking 182 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07100574Recruiting
Bacteria in dental plaque and artery plaque study
This study looks at bacteria found in dental plaque and in the fatty buildup inside your arteries. It might help researchers understand links between mouth health and blood vessel health after your endarterectomy surgery.
IstanbulAges 18–85 - NCT07234591Recruiting
Study of an oral medication for moderate to severe plaque psoriasis
This study tests an experimental oral medication (a TYK2 inhibitor) for people with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective at reducing psoriasis symptoms.
ShanghaiAges 18–70 - NCT06939374Recruiting
Freezing heart arteries to stabilize high-risk plaques
This study tests a special cooling balloon to freeze and stabilize dangerous plaques in heart arteries that are not the main cause of your current symptoms. It aims to prevent future heart attacks.
AalstAges 18 years+ - NCT07004673Recruiting
PET/MR imaging for carotid artery plaque risk
This trial uses special PET/MR scans to look at fatty buildup in your neck arteries to see which ones might be dangerous. It could help doctors better understand your stroke risk and choose the right treatment.
Shanghai, Shanghai MunicipalityAges Any age - NCT07107971Recruiting
Drug balloon vs. standard care for fatty heart plaques
This study compares a drug-coated balloon (which releases medicine into the artery) with standard medicines alone for treating fatty plaques in the heart arteries. It is for people who have already had a heart attack and a successful opening of a blocked artery.
AmsterdamAges 18 years+ - NCT06194526Enrolling by invitation
Blood test to measure heart artery plaque
This study is testing whether a new blood test can detect the amount of plaque buildup in your heart arteries compared to what a CT scan shows. It may help people with known or suspected coronary artery disease get a simpler, faster way to check their heart health.
Ciudad Autónoma de Buenos Aire, Buenos Aires F.D.Ages 18–75 - NCT06025305Enrolling by invitation
Using AI to find dangerous heart plaque on CT scans
This study uses artificial intelligence to look at CT scans of the heart to find which fatty deposits (plaque) in the arteries might be dangerous. It may help doctors better predict heart attacks.
Nanjing, JiangsuAges 18 years+ - NCT07324720Recruiting
Comparing ischemia vs plaque risk for high-risk artery disease
This trial compares two ways to decide which heart artery blockages need treatment: one looks at blood flow, the other at plaque buildup and risk. It's for people with high-risk blockages to see which approach leads to better outcomes.
Seoul, Main BuildingAges 19 years+ - NCT07706647Recruiting
Oil pulling for gum health trial
This study tests if oil pulling (swishing oil in your mouth) can reduce gum inflammation and bleeding. It compares oil pulling to a standard mouthwash to see which is better for gum health.
San Antonio, TexasAges 18–70 - NCT07762664Recruiting
Photon-counting CT versus regular CT for evaluating carotid artery narrowing before stenting
This study compares two types of CT scans to evaluate the arteries in your neck before you have a stent placed. The newer photon-counting CT may provide more detailed images, which could help your doctor plan the procedure more precisely.
Beijing, Beijing MunicipalityAges 10–90 - NCT07779564Recruiting
Electric flosser study for plaque and gum health
This study tests whether an electric flosser is better than a manual toothbrush for reducing plaque and gum inflammation. Participants will use the electric flosser for 30 days while having regular checkups. This could help you learn a new way to improve your oral health.
Fort Wayne, IndianaAges 18–70 - NCT04772079RecruitingPhase 3
Test drug safety and effectiveness for youth plaque psoriasis
This study checks whether deucravacitinib works well and is safe in children and teens with moderate to severe plaque psoriasis. It also looks at drug levels in the body to help understand how the treatment behaves over time.
Ciudad Autonoma de Buenos Aires, Buenos AiresAges 4–18 - NCT06979453RecruitingPhase 3
A study of deucravacitinib for teens with plaque psoriasis
This trial tests an investigational oral medication called deucravacitinib for teenagers (adolescents) with moderate to severe plaque psoriasis. It aims to see if the drug is safe and works well.
Birmingham, AlabamaAges 12–17 - NCT07474792RecruitingPhase 2
Study of ORKA-002 for moderate-to-severe plaque psoriasis
This trial tests an investigational drug called ORKA-002 for people with moderate-to-severe plaque psoriasis. It aims to see how well different doses work and if they are safe. You may qualify if your psoriasis covers at least 10% of your body or if it has not responded well enough to other treatments.
Birmingham, AlabamaAges 18–79 - NCT05764772Recruiting
Testing features of plaque in symptomatic carotid narrowing
This study looks at the makeup of plaque in the carotid artery (the neck blood vessel to the brain) in people who recently had a stroke caused by that narrowing. Researchers will use MRI and planned surgery to see which plaque components may matter for stroke risk and outcomes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06842199RecruitingPhase 3
Testing a new pill for moderate to severe plaque psoriasis
This trial tests an experimental drug called ICP-488 for people with moderate to severe plaque psoriasis. It aims to see if the drug can improve symptoms and is safe, and may be an option if you need stronger treatment than creams or light therapy.
Hefei, AnhuiAges 18–75 - NCT04537689RecruitingPhase 4
Test ixekizumab and stopping it in plaque psoriasis
This study looks at how well ixekizumab (an injection medication) works for moderate-to-severe plaque psoriasis, and what happens when the treatment is withdrawn. It may help you learn whether stopping the medicine is safe and how skin disease outcomes change over time.
Outram ParkAges 22–90 - NCT07155798Recruiting
Bamboo vs. plastic toothbrush for plaque removal in teens
This trial compares a bamboo toothbrush to a regular plastic toothbrush to see which one does a better job removing plaque. If you are a teenager in good health, you can help find out which brush is better for your teeth and the planet.
CairoAges 12–18 - NCT07672561RecruitingPhase 3
Testing a new pill for moderate to severe plaque psoriasis
This study tests an experimental pill called WD-890 to see if it can help people with moderate to severe plaque psoriasis. The pill is compared to a placebo (a pill with no medicine) to check if it is safe and works well.
Nanjing, JiangsuAges 18–75 - NCT07449702RecruitingPhase 2
Long-term safety study of ORKA-001 for plaque psoriasis
This study is a continuation for people who already took ORKA-001 for plaque psoriasis and did well. It tests whether staying on the medicine keeps helping without any new safety concerns.
Fountain Valley, CaliforniaAges 18 years+ - NCT07410793RecruitingPhase 2
Acupuncture plus herbal cream vs standard cream for plaque psoriasis
This trial tests if adding a Chinese herbal cream to acupuncture works as well as adding a standard psoriasis cream (calcipotriol) to acupuncture. It's for people with mild to moderate plaque psoriasis and may offer a natural treatment option.
Muang, ChiangraiAges 18–65 - NCT06058546RecruitingPhase 2
Jiuweihuaban pill for plaque psoriasis
This trial tests a Chinese herbal pill for people with mild-to-moderate plaque psoriasis. The pill is meant to reduce redness, scaling, and inflammation by targeting a specific pattern in traditional Chinese medicine.
BeijingAges 18–65 - NCT07251998RecruitingPhase 2
A study of ICP-332 for moderate to severe plaque psoriasis
This trial tests an oral medication called ICP-332 versus a placebo (a pill with no active drug) for people with moderate to severe plaque psoriasis. The goal is to see if ICP-332 can improve skin symptoms and be safe.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07326813RecruitingPhase 3
Testing D-2570 for moderate to severe plaque psoriasis
This trial tests if a new oral medication called D-2570 can safely and effectively treat moderate to severe plaque psoriasis. It may be an option if your psoriasis covers a large area and has been stable for at least 6 months.
Shanghai, Shanghai MunicipalityAges 18–70
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Common questions
- Are there clinical trials for plaque?
- Yes. Clin2 currently lists 182 recruiting plaque studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a plaque trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a plaque trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.