Carotid Plaque clinical trials

Photon-Counting CT Versus Conventional CT for Carotid Plaque Assessment in Patients With Carotid Artery Stenosis

PET/MR imaging for carotid artery plaque risk

This trial uses special PET/MR scans to look at fatty buildup in your neck arteries to see which ones might be dangerous. It could help doctors better understand your stroke risk and choose the right treatment.

Testing features of plaque in symptomatic carotid narrowing

This study looks at the makeup of plaque in the carotid artery (the neck blood vessel to the brain) in people who recently had a stroke caused by that narrowing. Researchers will use MRI and planned surgery to see which plaque components may matter for stroke risk and outcomes.

3D ultrasound to see new blood vessels in carotid plaque

This trial uses a special 3D ultrasound with contrast dye to look at fatty buildup (plaque) in the neck arteries. It aims to find new, fragile blood vessels in the plaque that might increase stroke risk.

Study of DR10624 for high triglycerides and carotid artery plaque

This trial tests a new drug, DR10624, to see if it can lower high triglycerides and reduce plaque in the carotid artery (the main artery in your neck). It may help people with both conditions who are also overweight.

Studying unstable plaque in the carotid artery

This trial looks at specific markers in the blood to better understand unstable plaque in the carotid artery. It may help doctors identify which patients are at higher risk for stroke.

Carotid stent vs. medication for recent stroke risk

This trial tests if a carotid artery stent plus medication is better than medication alone at preventing another stroke in people who recently had a stroke or eye blockage caused by a non-narrowing but risky carotid plaque.

Ultrasound to study neck artery plaques and predict risk

This study uses different ultrasound techniques to look at plaques in the neck artery and predict future heart or stroke events. It may help doctors understand which plaques are more dangerous.

Shear wave test for carotid plaque stiffness

This trial uses a special ultrasound technique called shear wave elastography to measure how stiff fatty deposits (plaques) are in your neck arteries. It aims to see whether plaque stiffness can help doctors better understand your stroke risk.

Oral bacteria in carotid artery plaque study

This study looks at the bacteria living in your mouth and whether they are linked to plaque buildup in the carotid artery (the main artery in your neck). If you are already scheduled for surgery to remove that plaque, the researchers will take samples from your mouth and the plaque to compare them.

PET/MRI scan to detect inflammation in carotid artery disease

This study tests whether a special type of PET/MRI scan can help doctors see inflammation in the carotid artery after a stroke or mini-stroke. By using a radioactive tracer, the scan may identify which patients have dangerous plaque buildup that could lead to another stroke.

Imaging study of plaque in neck arteries before surgery

This study uses pictures (imaging) to learn more about plaque in the neck arteries in people who are being considered for carotid endarterectomy. The results may help doctors better understand artery plaque and improve care.

Statins and folic acid for unstable carotid plaque

This trial tests if adding folic acid to a statin can help stabilize plaques in the carotid artery (neck artery) to prevent stroke. You may qualify if you have carotid plaque and are not already on certain supplements.

Carotid artery narrowing treatment follow-up at clinic

This study follows people who are getting a procedure for carotid artery narrowing at the clinic. It aims to learn about outcomes after these treatments.

Prevention program for people at risk of type 2 diabetes

This trial looks at a personalized prevention approach for people who are at risk of developing type 2 diabetes. It may help by targeting your specific health factors before diabetes starts.

PET scan study of inflammation and cholesterol-lowering treatment

This study uses PET/CT and related scans to measure inflammation in artery plaque and how cholesterol-lowering treatment changes it. It may help researchers understand which treatments reduce artery inflammation for people with heart or blood-vessel disease and high LDL (“bad”) cholesterol.

Study brain inflammation in carotid artery narrowing after stroke or TIA

This Phase 2 study looks at a protein called ficolin-2 and whether it relates to brain inflammation after a short stroke-like event or eye blood vessel blockage caused by narrowed carotid arteries. If you recently had symptoms from the carotid artery and meet imaging and health criteria, you may be offered study-related assessments to better understand the cause and help future treatment decisions.

Treating gum disease to study heart artery inflammation after a heart attack

This study tests whether treating severe gum disease in people who recently had a heart attack can reduce inflammation in the artery plaque. It may help researchers understand if gum treatment could benefit heart health after a heart attack.