Clinical trials
Plaque clinical trials
Below are recruiting plaque clinical trials, each written for real people, not researchers. We’re tracking 179 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07764679RecruitingPhase 3
Brain scan to detect Alzheimer's plaques
This study tests a new PET brain scan that uses a special dye to show amyloid plaques, which are linked to Alzheimer's disease. It may help doctors see if your memory problems are caused by Alzheimer's or something else.
Beijing, Beijing MunicipalityAges 40 years+ - NCT07724366RecruitingPhase 3
Study of TQH3906 for moderate to severe plaque psoriasis
This trial tests an oral medication called TQH3906 for people with moderate to severe plaque psoriasis. It aims to see if the drug can improve skin symptoms and is for adults who have not had enough success with other treatments.
Beijing, Beijing MunicipalityAges 18–75 - NCT05438121Recruiting
Tests a drug-coated balloon to stabilize clogged heart arteries
This trial studies whether a drug-coated balloon can better treat new, narrowed spots in multiple coronary arteries and “stabilize” the plaque. It may help improve blood flow after a procedure called balloon angioplasty for selected patients.
Ansan-si, Gyeonggi-doAges 18–85 - NCT07693972Recruiting
Probiotic vs zinc mouthwash for bad breath and plaque in braces
This trial compares a probiotic mouthwash to a zinc and chlorhexidine mouthwash to see which is better at controlling bad breath and plaque for people with braces. It aims to find a gentler option that still works well.
Baghdad, AlkarghAges 18–30 - NCT07683065Recruiting
Secukinumab treatment in psoriasis patients with liver condition
This study looks at how well secukinumab works for psoriasis patients who also have a type of fatty liver disease called MASLD. It may help doctors understand if this treatment is a good option for people with both conditions.
Badalona, BarcelonaAges 18–100 - NCT07657676RecruitingPhase 4
Study of mazdutide for heart artery plaque in people who are overweight
This study tests whether mazdutide, a medicine that may help with weight and blood sugar, can reduce plaque buildup in the heart's arteries. It is for people who are overweight or obese and have some narrowing in their heart arteries but do not need immediate procedures like stents.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07660419Recruiting
Home cardiac rehab app for coronary plaque
This trial tests whether a smartphone-based home cardiac rehabilitation program can help slow or reverse plaque buildup in people with mild-to-moderate coronary artery narrowing. It may be an option if you have stable heart disease and can exercise at home with remote monitoring.
BeijingAges 18–70 - NCT07663331RecruitingPhase 4
Adalimumab for adults with non-infectious uveitis
This study tests an injection called adalimumab (Tebiovio®) to see if it helps control inflammation in the eyes of adults with non-infectious uveitis. It might be a good option if you are already on steroid pills and looking for another treatment.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06678594Recruiting
A standardized method for treating hardened heart artery blockages
This trial is testing a new step-by-step approach (algorithm) to treat hardened, calcified blockages in heart arteries during a stent procedure. The goal is to see if this standardized method helps improve outcomes for patients with these tough-to-treat blockages.
DublinAges 18 years+ - NCT06685016Recruiting
Study of dental health after IPR with clear aligners
This study looks at how the teeth and gums are doing after a common orthodontic step called IPR (a slight smoothing between teeth) in people wearing clear aligners. It will help understand if this procedure keeps your mouth healthy.
NaplesAges 17–100 - NCT07613294RecruitingPhase 3
Testing lepodisiran to reduce heart plaque buildup
This study tests whether a new medicine called lepodisiran can shrink plaque in heart arteries for adults with high Lp(a) (a type of cholesterol linked to heart disease) who have had a heart event or are at serious risk. The trial uses CT scans to monitor changes in your arteries.
La Jolla, CaliforniaAges 45–80 - NCT07602582RecruitingPhase 3
Donanemab Extension Study for Alzheimer's Disease
This is a follow-up study for people who already completed a previous donanemab trial (AACM). Donanemab is a medication designed to slow cognitive decline in early Alzheimer's disease by targeting amyloid buildup in the brain.
Phoenix, ArizonaAges 55 years+ - NCT07582783Recruiting
Treatment Persistence with Guselkumab for Moderate-to-Severe Plaque Psoriasis
This study tracks how well patients stick with guselkumab, a biologic injection medication for moderate-to-severe plaque psoriasis. Researchers want to understand real-world treatment outcomes in Romania to help improve psoriasis care.
BârladAges 18 years+ - NCT07535008Recruiting
Dental Cleaning to Prevent Graft-Versus-Host Disease
This study tests whether professional dental cleaning after a stem cell transplant can help prevent chronic graft-versus-host disease (GVHD), a condition where transplanted immune cells attack your body. You'll receive dental cleanings and be followed for one year to see if this simple preventive step reduces GVHD complications.
Seattle, WashingtonAges 18 years+ - NCT06751979Recruiting
Probiotics for people with braces
This trial tests if a probiotic can improve oral health for people with braces. It might help reduce plaque buildup around brackets and wires.
AarhusAges 10 years+ - NCT07532486Recruiting
Guselkumab dosing study for moderate-to-severe psoriasis
This study tests whether a higher dose of guselkumab (a biologic medicine) given less frequently works as well as the standard dose for treating moderate-to-severe plaque psoriasis. The goal is to find a dosing schedule that is both effective and convenient for patients.
Hangzhou, ZhejiangAges 18 years+ - NCT06508697Recruiting
Heart Plaque on CT and Events After Avoiding Stenting
This study looks at how features of plaque (fatty buildup) in the heart arteries, seen on a CT scan, relate to future heart events in people who decided not to have a stent placed based on a special blood flow test (FFR). It may help doctors better understand when it's safe to avoid stenting.
Toyoake, Aichi-kenAges 20 years+ - NCT07511647RecruitingPhase 3
Study of QL2106 for moderate to severe plaque psoriasis
This trial tests an injectable drug, QL2106, for people with moderate to severe plaque psoriasis. It may help if you are a candidate for light therapy or other systemic treatments.
Jining, ShandongAges 18 years+ - NCT07501455Recruiting
Studying toothpaste and mouth rinse effects on gum inflammation
This study tests whether using a certain toothpaste and mouth rinse can reduce gum inflammation (gingivitis) better than brushing alone. It is for people with mild to moderate gum disease who have not used tobacco or certain medications recently.
Somerville, MassachusettsAges 18–60 - NCT05642182RecruitingPhase 1
Study drug trial for mild to moderate plaque psoriasis
This Phase 1 study tests a new drug (SFA002) in adults with stable plaque psoriasis. It mainly focuses on safety and how the body responds, and may eventually help people with psoriasis plaques.
Pompano Beach, FloridaAges 18 years+ - NCT07489885RecruitingPhase 2
Study of D-2570 for moderate to severe plaque psoriasis
This trial tests an experimental drug, D-2570, for people with moderate to severe plaque psoriasis. It aims to see if the medication can safely improve skin symptoms.
Birmingham, AlabamaAges 18–70 - NCT07472049Recruiting
Imaging plaque activity in peripheral artery disease
This trial studies plaque activity in leg arteries using a new imaging method to understand artery disease better. It may help people with peripheral artery disease get more targeted treatment.
Edinburgh, MidlothianAges 18 years+ - NCT06789458Recruiting
Pro-resolution mediators in severe gum disease before and after treatment
This study looks at natural substances in your blood that help reduce gum inflammation. Researchers want to see how these substances change after standard gum disease treatment, which may lead to better ways to manage severe periodontitis.
Manial, Cairo GovernorateAges 18–80 - NCT06749106Recruiting
Using MRI to find bleeding in neck artery plaque
This study uses MRI scans that are already done as part of your stroke care to look for bleeding inside plaque in the neck arteries. The goal is to see if this bleeding can help predict stroke risk.
MunichAges 18 years+
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Common questions
- Are there clinical trials for plaque?
- Yes. Clin2 currently lists 179 recruiting plaque studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a plaque trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a plaque trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.