Clinical trials
Plaque clinical trials
Below are recruiting plaque clinical trials, each written for real people, not researchers. We’re tracking 181 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02784210RecruitingPhase 2
Steroid treatment to reduce inflammation in active MS lesions
This Phase 2 study tests whether corticosteroid medicine can reduce inflammation at the edge of active multiple sclerosis (MS) plaques seen on MRI. It may help calm “hot” areas in the brain where MS activity is happening.
Bethesda, MarylandAges 18–120 - NCT00950430Enrolling by invitationPhase 4
Brain scan study for amyloid plaques in adults
This study uses brain imaging to look for amyloid plaques (abnormal protein deposits) as people age. It may help researchers better understand how these changes develop over time.
Rochester, MinnesotaAges 30–100 - NCT07415733Recruiting
Gum health toothpaste study for people with bleeding gums
This trial tests a toothpaste designed to improve gum health in people who have gingival problems like bleeding gums. It aims to see if the toothpaste can reduce gum bleeding and improve overall gum condition.
Jakarta PusatAges 18 years+ - NCT07447648Recruiting
Evinacumab for plaque buildup in HoFH
This observational study looks at how adding evinacumab to standard cholesterol-lowering therapy affects plaque in the heart arteries of people with homozygous familial hypercholesterolemia (HoFH). It compares those who started evinacumab within the last 2 years to those on standard therapy alone, using CT scans taken before and after treatment.
ParisAges 12 years+ - NCT07472049Recruiting
Imaging plaque activity in peripheral artery disease
This trial studies plaque activity in leg arteries using a new imaging method to understand artery disease better. It may help people with peripheral artery disease get more targeted treatment.
Edinburgh, MidlothianAges 18 years+ - NCT07501455Recruiting
Studying toothpaste and mouth rinse effects on gum inflammation
This study tests whether using a certain toothpaste and mouth rinse can reduce gum inflammation (gingivitis) better than brushing alone. It is for people with mild to moderate gum disease who have not used tobacco or certain medications recently.
Somerville, MassachusettsAges 18–60 - NCT07532486Recruiting
Guselkumab dosing study for moderate-to-severe psoriasis
This study tests whether a higher dose of guselkumab (a biologic medicine) given less frequently works as well as the standard dose for treating moderate-to-severe plaque psoriasis. The goal is to find a dosing schedule that is both effective and convenient for patients.
Hangzhou, ZhejiangAges 18 years+ - NCT07660419Recruiting
Home cardiac rehab app for coronary plaque
This trial tests whether a smartphone-based home cardiac rehabilitation program can help slow or reverse plaque buildup in people with mild-to-moderate coronary artery narrowing. It may be an option if you have stable heart disease and can exercise at home with remote monitoring.
BeijingAges 18–70 - NCT07535229Enrolling by invitation
Frankincense and herbs for gum inflammation treatment
This study tests whether frankincense and herbal extracts can reduce gum inflammation and plaque buildup. You'll be randomly assigned to receive either the herbal treatment or a placebo (inactive substance) to see if the natural remedy helps your gums heal.
MuscatAges 18–30 - NCT06999941Enrolling by invitation
Study of deucravacitinib for psoriasis with eczema features
This trial tests an oral medication called deucravacitinib for people who have both psoriasis and eczema (or psoriasis that looks like eczema) on their skin. The goal is to see if it can help reduce the severity of their plaques and itch.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06980714Enrolling by invitation
Electric vs. manual toothbrush for advanced gum disease
This study compares electric and manual toothbrushes to see which one works better for people with advanced gum disease (stage 3 or 4 periodontitis). It might help you find a more effective way to care for your teeth and gums at home.
L’AquilaAges 18 years+ - NCT05893654Enrolling by invitationPhase 1/Phase 2
Melphalan treatment to shrink eye melanoma before other therapy
This early-phase study tests whether melphalan can be used to reduce (shrink) a type of eye cancer called choroidal melanoma before additional treatment. It may help by controlling tumor size while doctors closely monitor the eye and outcomes.
Ribeirão Preto, São PauloAges 18 years+ - NCT03308773Enrolling by invitation
Prevention program for people at risk of type 2 diabetes
This trial looks at a personalized prevention approach for people who are at risk of developing type 2 diabetes. It may help by targeting your specific health factors before diabetes starts.
Ages 18–100
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Common questions
- Are there clinical trials for plaque?
- Yes. Clin2 currently lists 181 recruiting plaque studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a plaque trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a plaque trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.