Clinical trials
Plaque clinical trials
Below are recruiting plaque clinical trials, each written for real people, not researchers. We’re tracking 181 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06696417Recruiting
Testing vunakizumab for moderate to severe plaque psoriasis
This study tests a new drug called vunakizumab to see if it is safe and works well for people with moderate to severe plaque psoriasis. If you have not used biologic treatments before and meet other health requirements, you may be able to join.
Shenyang, LiaoningAges 18 years+ - NCT07733089RecruitingPhase 1
Testing a new psoriasis drug for safety and effect
This trial tests a new study drug (ZP9830) to see if it is safe and works well for people with plaque psoriasis. You would receive the treatment for 8 weeks, and the study will check how your skin responds.
Leiden, South HollandAges 18–60 - NCT06258668Recruiting
Real-world study of Sotyktu for psoriasis in Korea
This study looks at how safe and effective a pill called Sotyktu is for people with moderate-to-severe plaque psoriasis in real-life medical settings in Korea. If you are 19 or older and are about to start Sotyktu for your psoriasis as your doctor prescribes, this study may be an option for you.
SeoulAges 19 years+ - NCT07250802RecruitingPhase 3
Long-term study of zasocitinib for children with plaque psoriasis
This trial tests a daily pill (zasocitinib) for children and teens with moderate to severe plaque psoriasis that hasn't been controlled by other treatments. It aims to see if the pill can safely improve skin symptoms over a long period.
Chula Vista, CaliforniaAges 4–17 - NCT07024602RecruitingPhase 1
Testing ASC50 tablets for plaque psoriasis
This study tests an investigational tablet called ASC50 for plaque psoriasis. It aims to see if it is safe and works well for people with this skin condition.
Miami, FloridaAges 18–65 - NCT06382987Recruiting
Comparing deucravacitinib vs apremilast for plaque psoriasis
This study compares two oral medications, deucravacitinib and apremilast, for adults with plaque psoriasis in Japan. It looks at how well each drug works in real-world use.
Minato-ku, TokyoAges 18 years+ - NCT07038720RecruitingPhase 1
Testing an experimental oral tablet for moderate to severe psoriasis
This early-phase study tests an experimental oral tablet (UA026) in people with moderate to severe plaque psoriasis. The purpose is to see how safe and effective the drug is, and how it works in the body.
Hangzhou, ZhejiangAges 18–55 - NCT07545902Recruiting
Urea-based creams for plaque and palm-sole psoriasis
This study tests two medicated creams containing urea (a natural moisturizing ingredient) to treat psoriasis on the skin and on the palms and soles of the feet. The creams may help reduce flaking, scaling, and irritation in people with mild psoriasis.
Chieti, ItaliaAges 18–65 - NCT07337434RecruitingEarly Phase 1
Comparing two pills for moderate to severe psoriasis
This trial tests two oral medications, Apremilast and Methotrexate, to see which works better for people with moderate to severe plaque psoriasis. You must not have taken systemic treatments (pills or shots that work throughout the body) in the last 3 months.
Peshawar, Khyber PukhtunkhwaAges 18–60 - NCT07706647Recruiting
Oil pulling for gum health trial
This study tests if oil pulling (swishing oil in your mouth) can reduce gum inflammation and bleeding. It compares oil pulling to a standard mouthwash to see which is better for gum health.
San Antonio, TexasAges 18–70 - NCT04772079RecruitingPhase 3
Test drug safety and effectiveness for youth plaque psoriasis
This study checks whether deucravacitinib works well and is safe in children and teens with moderate to severe plaque psoriasis. It also looks at drug levels in the body to help understand how the treatment behaves over time.
Ciudad Autonoma de Buenos Aires, Buenos AiresAges 4–18 - NCT05821894Recruiting
Imaging study of plaque in neck arteries before surgery
This study uses pictures (imaging) to learn more about plaque in the neck arteries in people who are being considered for carotid endarterectomy. The results may help doctors better understand artery plaque and improve care.
Malmö, Skåne CountyAges 18 years+ - NCT06030076Recruiting
Switching to tildrakizumab for moderate to severe psoriasis
This trial is for adults with moderate to severe plaque psoriasis who are currently on a biologic treatment (like Humira, Stelara, or Cosentyx) and are switching to tildrakizumab. It looks at how your quality of life and symptoms change after the switch.
Graz, StyriaAges 18 years+ - NCT06473272Recruiting
Ultrasound to study neck artery plaques and predict risk
This study uses different ultrasound techniques to look at plaques in the neck artery and predict future heart or stroke events. It may help doctors understand which plaques are more dangerous.
Shanghai, Shanghai MunicipalityAges 40–100 - NCT06511830Recruiting
Comparing plaque detection methods for better dental care
This study compares different ways of checking dental plaque (the sticky film on teeth) to see which method works best. It may help you understand how to better care for your teeth and gums.
Lincoln, NebraskaAges 19–85 - NCT06517238Recruiting
Digital tool to improve dental care during braces treatment
This trial tests a new digital communication tool that helps your dentist and orthodontist work together better. The goal is to improve how your teeth are cared for while you have braces.
ReimsAges 8–18 - NCT06603363Recruiting
Statin effects on heart artery plaques seen on CT scans
This trial studies how short-term statin therapy changes plaque buildup in heart arteries. It uses CT scans to see if statins can make plaques more stable and reduce heart risks.
Budapest, BudapestAges 45–75 - NCT06767345RecruitingPhase 4
Comparing two cholesterol medicines for plaque stabilization
This study compares two ways to lower cholesterol and stabilize artery plaque in people with coronary artery disease who are having a stent procedure. It tests whether a moderate statin plus ezetimibe works as well as a high-intensity statin alone for stabilizing plaque.
Seoul, SeoulAges 18 years+ - NCT06855537RecruitingPhase 4
Stent for vulnerable plaques in heart patients
This trial tests whether implanting stents in non-obstructive, high-risk plaques (thin-capped fatty plaques) can prevent future heart attacks. It is for people who have already had treatment for a recent heart attack or unstable angina and have additional plaques that are not severely blocking blood flow but are vulnerable.
Beijing, Beijing MunicipalityAges 18–80 - NCT06984744Recruiting
Gum health study testing a new compound
This study tests a compound in gum to see how well it prevents plaque buildup over 4 days. You may be able to join if you are a healthy adult with at least 20 natural teeth and some existing plaque.
Indianapolis, IndianaAges 18–65 - NCT07243782Recruiting
Study of Cosentyx for skin and joint conditions in Korea
This study tracks how well Cosentyx works in real-world use for people with hidradenitis suppurativa, plaque psoriasis, or juvenile idiopathic arthritis. It helps doctors understand the medicine's long-term effects in Korean patients.
Seoul, SeoulAges 6–100 - NCT07298655Recruiting
3D ultrasound to see new blood vessels in carotid plaque
This trial uses a special 3D ultrasound with contrast dye to look at fatty buildup (plaque) in the neck arteries. It aims to find new, fragile blood vessels in the plaque that might increase stroke risk.
HarrowAges 18 years+ - NCT07324720Recruiting
Comparing ischemia vs plaque risk for high-risk artery disease
This trial compares two ways to decide which heart artery blockages need treatment: one looks at blood flow, the other at plaque buildup and risk. It's for people with high-risk blockages to see which approach leads to better outcomes.
Seoul, Main BuildingAges 19 years+ - NCT07356869Recruiting
Mouthwash study for school children's dental health
This study compares two mouthwashes (one with probiotics and one with a natural ingredient called ethyl lauroyl arginate) to see which is better at reducing cavity-causing bacteria, plaque buildup, and keeping the mouth at a healthy pH level. It may help children between 6 and 12 years old who have mild to moderate plaque.
CairoAges 6–12
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Common questions
- Are there clinical trials for plaque?
- Yes. Clin2 currently lists 181 recruiting plaque studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a plaque trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a plaque trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.