Clinical trials
Plaque clinical trials
Below are recruiting plaque clinical trials, each written for real people, not researchers. We’re tracking 179 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07611942Recruiting
Plaque Removal in Children With Learning Disabilities
This study compares how well children with learning disabilities can remove plaque from their teeth compared to children without learning disabilities. It aims to understand if dental plaque removal is harder for children with specific learning challenges.
Alanya, AntalyaAges 7–12 - NCT06473272Recruiting
Ultrasound to study neck artery plaques and predict risk
This study uses different ultrasound techniques to look at plaques in the neck artery and predict future heart or stroke events. It may help doctors understand which plaques are more dangerous.
Shanghai, Shanghai MunicipalityAges 40–100 - NCT07555223Recruiting
Using 3D Scans to Better Detect Tooth Decay
This study tests whether special 3D imaging and intraoral scanning tools can help dentists better identify tooth decay and plaque buildup. Researchers want to see if these new methods work well and could improve how cavities are diagnosed.
Wondelgem, BotestraatAges 18–70 - NCT07545902Recruiting
Urea-based creams for plaque and palm-sole psoriasis
This study tests two medicated creams containing urea (a natural moisturizing ingredient) to treat psoriasis on the skin and on the palms and soles of the feet. The creams may help reduce flaking, scaling, and irritation in people with mild psoriasis.
Chieti, ItaliaAges 18–65 - NCT07470528Recruiting
Comparing two surgeries for complex Peyronie's disease
This trial compares two surgical techniques to correct severe penile curvature caused by Peyronie's disease. It tests which approach works better for men with advanced or complex cases.
TekirdağAges 18 years+ - NCT06030076Recruiting
Switching to tildrakizumab for moderate to severe psoriasis
This trial is for adults with moderate to severe plaque psoriasis who are currently on a biologic treatment (like Humira, Stelara, or Cosentyx) and are switching to tildrakizumab. It looks at how your quality of life and symptoms change after the switch.
Graz, StyriaAges 18 years+ - NCT07449702RecruitingPhase 2
Long-term safety study of ORKA-001 for plaque psoriasis
This study is a continuation for people who already took ORKA-001 for plaque psoriasis and did well. It tests whether staying on the medicine keeps helping without any new safety concerns.
Phoenix, ArizonaAges 18 years+ - NCT07414173RecruitingPhase 4
Mouthrinse for plaque and gum health
This study tests whether a special antimicrobial mouthrinse can reduce plaque buildup and improve gum health over 6 months. If you have early gum disease (gingivitis) and are generally healthy, this trial may be a good fit.
SchenefeldAges 18–70 - NCT07410793RecruitingPhase 2
Acupuncture plus herbal cream vs standard cream for plaque psoriasis
This trial tests if adding a Chinese herbal cream to acupuncture works as well as adding a standard psoriasis cream (calcipotriol) to acupuncture. It's for people with mild to moderate plaque psoriasis and may offer a natural treatment option.
Muang, ChiangraiAges 18–65 - NCT07362017RecruitingPhase 3
Ponesimod for moderate to severe plaque psoriasis
This trial tests an investigational drug called ponesimod for people with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective at improving skin symptoms.
Glendale, ArizonaAges 18–65 - NCT07356869Recruiting
Mouthwash study for school children's dental health
This study compares two mouthwashes (one with probiotics and one with a natural ingredient called ethyl lauroyl arginate) to see which is better at reducing cavity-causing bacteria, plaque buildup, and keeping the mouth at a healthy pH level. It may help children between 6 and 12 years old who have mild to moderate plaque.
CairoAges 6–12 - NCT07337434RecruitingEarly Phase 1
Comparing two pills for moderate to severe psoriasis
This trial tests two oral medications, Apremilast and Methotrexate, to see which works better for people with moderate to severe plaque psoriasis. You must not have taken systemic treatments (pills or shots that work throughout the body) in the last 3 months.
Peshawar, Khyber PukhtunkhwaAges 18–60 - NCT07326813RecruitingPhase 3
Testing D-2570 for moderate to severe plaque psoriasis
This trial tests if a new oral medication called D-2570 can safely and effectively treat moderate to severe plaque psoriasis. It may be an option if your psoriasis covers a large area and has been stable for at least 6 months.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07324720Recruiting
Comparing ischemia vs plaque risk for high-risk artery disease
This trial compares two ways to decide which heart artery blockages need treatment: one looks at blood flow, the other at plaque buildup and risk. It's for people with high-risk blockages to see which approach leads to better outcomes.
Seoul, Main BuildingAges 19 years+ - NCT07298655Recruiting
3D ultrasound to see new blood vessels in carotid plaque
This trial uses a special 3D ultrasound with contrast dye to look at fatty buildup (plaque) in the neck arteries. It aims to find new, fragile blood vessels in the plaque that might increase stroke risk.
HarrowAges 18 years+ - NCT07250802RecruitingPhase 3
Long-term study of zasocitinib for children with plaque psoriasis
This trial tests a daily pill (zasocitinib) for children and teens with moderate to severe plaque psoriasis that hasn't been controlled by other treatments. It aims to see if the pill can safely improve skin symptoms over a long period.
Chula Vista, CaliforniaAges 4–17 - NCT07251998RecruitingPhase 2
A study of ICP-332 for moderate to severe plaque psoriasis
This trial tests an oral medication called ICP-332 versus a placebo (a pill with no active drug) for people with moderate to severe plaque psoriasis. The goal is to see if ICP-332 can improve skin symptoms and be safe.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07243782Recruiting
Study of Cosentyx for skin and joint conditions in Korea
This study tracks how well Cosentyx works in real-world use for people with hidradenitis suppurativa, plaque psoriasis, or juvenile idiopathic arthritis. It helps doctors understand the medicine's long-term effects in Korean patients.
Seoul, SeoulAges 6–100 - NCT07155798Recruiting
Bamboo vs. plastic toothbrush for plaque removal in teens
This trial compares a bamboo toothbrush to a regular plastic toothbrush to see which one does a better job removing plaque. If you are a teenager in good health, you can help find out which brush is better for your teeth and the planet.
CairoAges 12–18 - NCT07130604RecruitingPhase 3
Testing a new pill for moderate to severe plaque psoriasis
This trial tests an experimental pill called D-2570 for people with moderate to severe plaque psoriasis. It aims to see if the pill can safely improve skin symptoms like redness, scaling, and thickness.
Beijing, Beijing MunicipalityAges 18–70 - NCT07129382RecruitingPhase 1/Phase 2
Study of CS32582 for moderate to severe plaque psoriasis
This trial tests a new oral medication, CS32582, for people with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective at reducing skin symptoms like redness, thickness, and scaling.
Beijing, Beijing MunicipalityAges 18–70 - NCT06696417Recruiting
Testing vunakizumab for moderate to severe plaque psoriasis
This study tests a new drug called vunakizumab to see if it is safe and works well for people with moderate to severe plaque psoriasis. If you have not used biologic treatments before and meet other health requirements, you may be able to join.
Shenyang, LiaoningAges 18 years+ - NCT07050134Enrolling by invitation
Study of DR10624 for high triglycerides and carotid artery plaque
This trial tests a new drug, DR10624, to see if it can lower high triglycerides and reduce plaque in the carotid artery (the main artery in your neck). It may help people with both conditions who are also overweight.
Hefei, AnhuiAges 18–65 - NCT07039110Recruiting
Risankizumab for psoriasis: quality of life study
This study looks at how risankizumab (Skyrizi) affects the quality of life for adults with moderate-to-severe plaque psoriasis. It is an observational study, meaning no new treatments are given—researchers simply follow patients who are already being treated with risankizumab as part of their regular care.
Calgary, AlbertaAges 18 years+
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Common questions
- Are there clinical trials for plaque?
- Yes. Clin2 currently lists 179 recruiting plaque studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a plaque trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a plaque trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.