Clinical trials
Portosystemic Shunt clinical trials
Below are recruiting portosystemic shunt clinical trials, each written for real people, not researchers. We’re tracking 18 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06041906Enrolling by invitation
International registry for congenital portosystemic shunt
This registry is gathering information from people who have a rare liver blood vessel problem they were born with (congenital portosystemic shunt). By joining, you help researchers learn more about this condition and improve future care.
New Haven, ConnecticutAges 1 day+ - NCT07172035Recruiting
TIPS and liver recovery in decompensated cirrhosis
This trial studies whether a procedure called TIPS (a stent placed in the liver to improve blood flow) can help people with advanced liver disease regain better liver function. It is for patients who have had complications like severe bleeding from the stomach or difficult-to-control fluid buildup (ascites).
ChangshaAges 18–80 - NCT05782556Recruiting
Freiburg TIPS Registry for portal hypertension patients
This is a registry study that collects information from people who need a procedure called TIPS for portal hypertension. It may help doctors better understand outcomes and care for both cirrhotic and non-cirrhotic causes of portal hypertension.
Freiburg im BreisgauAges 18–100 - NCT06646198RecruitingPhase 2
TIPS with half-dose Donafenib for liver cancer with portal hypertension
This trial tests a treatment that combines a procedure called TIPS with a targeted therapy drug (Donafenib) at half strength. It is for people with advanced liver cancer that has spread into the portal vein and caused high blood pressure in the liver (portal hypertension). The goal is to see if this combination can help control the cancer and reduce complications.
Guangzhou, GuangdongAges 18–75 - NCT03121404Recruiting
Study causes of poor nutrition in people with liver scarring
This study looks at why some people with cirrhosis (liver scarring) develop malnutrition, especially when blood flow is redirected during certain surgeries. It may help explain what contributes to low body weight and muscle so better treatments can be planned in the future.
Cleveland, OhioAges 18–70 - NCT06624098Recruiting
Early TIPS for Advanced Liver Cancer with Vein Blockage
This study tests whether placing a small tube (TIPS) early in people with advanced liver cancer and a vein blockage helps their other treatments work better. It is for patients who are already taking lenvatinib and immunotherapy.
Beijing, Beijing MunicipalityAges 18–75 - NCT06814990Recruiting
Heart and liver study for TIPSS patients
This study uses MRI and echocardiography to check heart function in people with alcohol-related liver cirrhosis who need a TIPSS procedure. It aims to learn more about how the heart works in these patients.
Jena, ThuringiaAges 18–99 - NCT03409263Recruiting
Registry for people with TIPS for high portal pressure
This study is a registry, meaning it collects health information to better understand people who have a TIPS procedure for high pressure in the liver’s blood vessels. It may help doctors improve how TIPS is used and monitored over time.
Vienna, State of ViennaAges 18–99 - NCT06814626RecruitingPhase 3
Nutrition therapy for muscle loss in cirrhosis with fluid buildup
This trial tests whether a special nutrition plan can help treat muscle loss in people with liver cirrhosis who also have fluid buildup that doesn't improve with standard treatment. It aims to improve strength and outcomes after a procedure to place a shunt in the liver.
PalermoAges 18–80 - NCT05882370RecruitingPhase 2
Immunotherapy plus TIPS for liver cancer with blocked portal vein
This study tests whether adding the immunotherapy drug cadonilimab (and a related treatment plan) plus TIPS can help people with advanced liver cancer that has a tumor clot causing portal vein pressure problems. It aims to improve disease control while managing the circulation pressure in the liver.
Guangzhou, GuangdongAges 18–75 - NCT06117735Recruiting
Covered stent for portal hypertension
This trial tests a special stent to treat high blood pressure in the liver caused by cirrhosis. It may help patients who need a procedure called TIPS to improve blood flow.
Fuzhou, FujianAges 18–85 - NCT06576934Recruiting
Early TIPS for liver cirrhosis with ascites
This study tests whether placing a small tube (called a TIPS) early in the liver can help people with cirrhosis who have their first episode of moderate to severe belly fluid buildup. The goal is to see if this early procedure improves outcomes compared to standard care.
Freiburg im BreisgauAges 18–80 - NCT06622031Recruiting
TIPS with lenvatinib and immunotherapy for advanced liver cancer
This trial combines a procedure called TIPS (which helps relieve pressure in the liver) with two drugs—lenvatinib (a targeted therapy) and a PD-1 inhibitor (an immunotherapy)—for people with advanced liver cancer that has spread into the main vein of the liver. It aims to see if this combination can help control the cancer and improve symptoms.
Beijing, None SelectedAges 18–75 - NCT06794853Recruiting
TIPS for improving muscle wasting in liver cirrhosis
This study looks at how a treatment called TIPS (a procedure to reduce pressure in the liver) might help improve muscle wasting (sarcopenia) in people with liver cirrhosis. If you are scheduled for TIPS, researchers want to see if it can stop or reverse muscle loss.
WuhanAges 18–80 - NCT07058155RecruitingPhase 4
TIPS and weight-loss surgery for liver disease with high blood pressure
This trial tests if doing a TIPS procedure (to lower blood pressure in the liver) before weight-loss surgery (sleeve gastrectomy) helps people with advanced liver disease. It's for those who have cirrhosis and very high blood pressure in the liver, and who qualify for sleeve gastrectomy.
Cleveland, OhioAges 18–70 - NCT07111221Recruiting
Reducing bleeding risk before liver transplant
This trial tests a procedure to lower blood loss during liver transplant for patients with high blood pressure in the liver. It may help those who have had a previous transplant, abdominal surgery, or certain complications of liver disease.
WarsawAges 18 years+ - NCT07281846Recruiting
TIPS with or without BCAA for cirrhosis and muscle wasting
This trial tests whether adding branched-chain amino acids (BCAA) to the standard TIPS procedure helps people with cirrhosis and muscle wasting. It aims to see if BCAA can improve outcomes after TIPS.
WuhanAges 18–80 - NCT07439939Recruiting
Blood Clotting Study in Cirrhosis Patients Getting a TIPS
This study looks at blood clotting in patients with cirrhosis who are getting a TIPS—a tube placed in the liver to help blood flow. The study aims to understand how the procedure affects bleeding and clotting, which could help make it safer for people with liver disease.
VillejuifAges 18 years+
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Common questions
- Are there clinical trials for portosystemic shunt?
- Yes. Clin2 currently lists 18 recruiting portosystemic shunt studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a portosystemic shunt trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a portosystemic shunt trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.