Clinical trials
Post-stroke Depression clinical trials
Below are recruiting post-stroke depression clinical trials, each written for real people, not researchers. We’re tracking 39 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05976152RecruitingPhase 3
Butyphthalide to improve thinking after a recent stroke
This Phase 3 study tests whether butyphthalide can help thinking and memory improve after an acute ischemic stroke. It compares people who take the study medicine versus usual care, and measures cognitive (thinking) changes over follow-up.
Dandong, LiaoningAges 60 years+ - NCT07809269Recruiting
Healthy lifestyle support after stroke
This study tests a program to help people who have had a stroke adopt healthier habits, like being more active, eating better, quitting smoking, cutting down on alcohol, taking medications as prescribed, or managing stress and mood.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT07736885Recruiting
Hand stimulation for thinking problems after stroke
This study tests a gentle, painless electrical stimulation on specific points on the hands to see if it helps improve thinking and memory after a stroke. It is for people who have had a stroke in the last 2 weeks to 6 months and are noticing some cognitive changes.
Tianjin, Tianjin MunicipalityAges 35–80 - NCT06516588RecruitingPhase 2
Brain stimulation for memory and thinking after stroke
This trial tests if a gentle brain stimulation technique called tDCS can help improve memory and thinking in people who have had a stroke. It is for those who are still in the early recovery phase (between 10 days and 5 months after their stroke) and have some ongoing cognitive problems.
Oklahoma City, OklahomaAges 18–99 - NCT07691411Recruiting
Smartphone app for stroke recovery support
This study uses a smartphone app to help you manage your recovery after a stroke. It sends you quick questions and tips throughout the day to support your self-care and well-being.
Hong Kong, Hong KongAges 18 years+ - NCT07660263Recruiting
Predicting dementia after stroke with genetics and imaging
This study aims to develop a tool that predicts the risk of dementia after a stroke using genetic and imaging data. It enrolls both healthy adults and people who have had a stroke in the last 3 years.
Gyeonggi-do, Gyeonggi-doAges 19 years+ - NCT07603102Recruiting
Mindfulness and Walking Training for Memory After Stroke
This study tests whether combining mindfulness meditation with balance and walking exercises can help improve memory and thinking skills in people who had a stroke. The trial focuses on people with mild cognitive impairment—difficulty thinking clearly—after stroke recovery.
NanjingAges 55 years+ - NCT07452276Recruiting
AI brain training for stroke recovery
This trial tests a computerized brain-training program that uses artificial intelligence to help people with memory problems after a stroke. If you are between 45 and 60 and had a stroke at least 3 months ago, you may be able to join.
Cairo, EgyptAges 45–60 - NCT07444151Recruiting
Post-stroke fatigue perception study
This study explores fatigue after stroke. If you have ongoing tiredness that you believe stems from your stroke, researchers want to learn from your experience through a questionnaire.
Carouge, Canton of GenevaAges 18 years+ - NCT06846177Recruiting
Training programs for fatigue after stroke
This study compares two types of training—graded activity and task-oriented training—to see which one helps reduce fatigue after a stroke. If you are between 40 and 60 years old, had a stroke over 4 months ago, and often feel very tired, you may be able to join.
Mansehra, KPKAges 40–60 - NCT07294274Recruiting
Predicting depression risk after a stroke
This study creates a tool to predict if someone might develop depression after an ischemic stroke. It aims to help doctors identify and support patients who are at higher risk.
ChongqingAges Any age - NCT06876597Recruiting
Robotic arm therapy for stroke recovery
This trial tests a robotic arm system that combines movement and thinking tasks to help people recover arm function after a first stroke. It is for people aged 40–80 who had a stroke within the last 2 weeks to 6 months and have some arm weakness but not too severe.
FuzhouAges 40–80 - NCT07144436Recruiting
Pain after stroke: brain scan and treatment study
This trial tests whether a special kind of brain scan (called tAN-fMRI) can help understand and treat pain that happens after a stroke. You may qualify if you had a stroke at least 6 months ago and are between 18 and 80 years old.
Charleston, South CarolinaAges 18–80 - NCT07113990Recruiting
Electroacupuncture and brain stimulation for stroke recovery
This trial tests whether combining two therapies—electroacupuncture (needles with mild electric current) and rTMS (a magnetic pulse to the brain)—can help you regain movement after a stroke. It is designed for people who had their first stroke less than 6 months ago and are still working on motor recovery.
Fuzhou, FujianAges 40–75 - NCT06772194Recruiting
Taiwan Recovery After Stroke Study
This study looks at how people recover after a stroke. Researchers will check your thinking, memory, and daily function over a year to learn more about recovery patterns and help design better treatments.
TaipeiAges 18 years+ - NCT04911738Recruiting
Virtual reality glasses to improve balance after stroke
This trial studies whether virtual reality glasses training can improve balance and body alignment after a recent stroke. It will also compare how stroke participants with balance problems respond versus people without stroke.
GrenobleAges 18–80 - NCT07050355Recruiting
Brain stimulation and exercise for depression after stroke
This study tests whether combining brain stimulation with aerobic exercise can help treat depression and improve walking in people who have had a stroke at least a year ago. If you have ongoing depressive symptoms and some leg weakness from your stroke, this treatment may help you feel better and walk more easily.
Durham, North CarolinaAges 21 years+ - NCT07039305Recruiting
Building physical strength after stroke
This study looks at whether a specific exercise program can help people with chronic stroke (more than 6 months ago) who still have some weakness in their leg. It aims to improve walking and overall physical ability.
Charleston, South CarolinaAges 18–80 - NCT06864715Recruiting
Preventing depression after a stroke with behavioral activation
This study tests if a talking therapy called behavioral activation can prevent depression in older adults who have had a stroke and have low income. It is for people who are not already severely depressed and live at home.
Houston, TexasAges 55 years+ - NCT06787508Enrolling by invitation
Brain stimulation for speech recovery after stroke
This study tests whether repeated sessions of transcranial magnetic stimulation (a non-invasive brain stimulation therapy) can help people who recently had a stroke and are having trouble speaking (aphasia). It is for patients who were hospitalized within the last 7 days and are right-handed.
Chongqing, Municipality Directly Under the Central GovernmentAges 18 years+ - NCT06759558RecruitingPhase 2
Zuranolone for post-stroke depression
This trial tests a new medicine called zuranolone (allopregnanolone) for people with depression after a stroke. It aims to see if the drug can help improve mood when taken over a short period.
Durham, North CarolinaAges 21–65 - NCT06479174Recruiting
Cognitive strategies after stroke with family support
This study tests if combining cognitive exercises with a safe, mild brain stimulation can help improve memory and thinking after a stroke. It also looks at how shared family health history might affect recovery.
Albuquerque, New MexicoAges 18 years+ - NCT06446960RecruitingPhase 3
Nerve blocks for stroke-related central pain
This study tests whether numbing the nerves in your painful arm or leg (with a nerve block) can help reduce central pain after a stroke. It aims to find out how the nerves outside your brain and spinal cord may be involved.
Boulogne-BillancourtAges 18 years+ - NCT06212219Recruiting
EEG brain training to help arm recovery after stroke
This study tests whether a brain-training technique called neurofeedback can improve arm movement in people who recently had a stroke. It uses an EEG cap to measure your brain activity while you do arm exercises, helping you relearn how to move your affected arm.
ToulouseAges 18–99
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Common questions
- Are there clinical trials for post-stroke depression?
- Yes. Clin2 currently lists 39 recruiting post-stroke depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post-stroke depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post-stroke depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.