Clinical trials
Post-stroke Depression clinical trials
Below are recruiting post-stroke depression clinical trials, each written for real people, not researchers. We’re tracking 40 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06864715Recruiting
Preventing depression after a stroke with behavioral activation
This study tests if a talking therapy called behavioral activation can prevent depression in older adults who have had a stroke and have low income. It is for people who are not already severely depressed and live at home.
Houston, TexasAges 55 years+ - NCT06846177Recruiting
Training programs for fatigue after stroke
This study compares two types of training—graded activity and task-oriented training—to see which one helps reduce fatigue after a stroke. If you are between 40 and 60 years old, had a stroke over 4 months ago, and often feel very tired, you may be able to join.
Mansehra, KPKAges 40–60 - NCT07294274Recruiting
Predicting depression risk after a stroke
This study creates a tool to predict if someone might develop depression after an ischemic stroke. It aims to help doctors identify and support patients who are at higher risk.
ChongqingAges Any age - NCT07050355Recruiting
Brain stimulation and exercise for depression after stroke
This study tests whether combining brain stimulation with aerobic exercise can help treat depression and improve walking in people who have had a stroke at least a year ago. If you have ongoing depressive symptoms and some leg weakness from your stroke, this treatment may help you feel better and walk more easily.
Durham, North CarolinaAges 21 years+ - NCT07736885Recruiting
Hand stimulation for thinking problems after stroke
This study tests a gentle, painless electrical stimulation on specific points on the hands to see if it helps improve thinking and memory after a stroke. It is for people who have had a stroke in the last 2 weeks to 6 months and are noticing some cognitive changes.
Tianjin, Tianjin MunicipalityAges 35–80 - NCT06479174Recruiting
Cognitive strategies after stroke with family support
This study tests if combining cognitive exercises with a safe, mild brain stimulation can help improve memory and thinking after a stroke. It also looks at how shared family health history might affect recovery.
Albuquerque, New MexicoAges 18 years+ - NCT07660263Recruiting
Predicting dementia after stroke with genetics and imaging
This study aims to develop a tool that predicts the risk of dementia after a stroke using genetic and imaging data. It enrolls both healthy adults and people who have had a stroke in the last 3 years.
Gyeonggi-do, Gyeonggi-doAges 19 years+ - NCT04144972Recruiting
Closed-loop deep brain stimulation for long-lasting nerve pain
This trial tests a “smart” deep brain stimulation device that senses your brain signals and adjusts treatment to reduce severe, long-lasting pain. It may help people whose pain has not improved with multiple pain medicines and surgery cannot fix the cause.
San Francisco, CaliforniaAges 22–80 - NCT04911738Recruiting
Virtual reality glasses to improve balance after stroke
This trial studies whether virtual reality glasses training can improve balance and body alignment after a recent stroke. It will also compare how stroke participants with balance problems respond versus people without stroke.
GrenobleAges 18–80 - NCT05303649Recruiting
Theta burst brain stimulation for language problems after stroke
This study tests whether a type of brain stimulation guided by a brain scan (MRI) can improve speech and language (“aphasia”) after a stroke. It may help people who have trouble producing speech but can still understand others’ words.
Warsaw, Masovian VoivodeshipAges 18–75 - NCT05507138RecruitingPhase 2
Digital therapy for depression and thinking problems after stroke
This Phase 2 trial tests a smartphone/tablet-based program to improve post-stroke depression and executive thinking skills (like planning and attention). It may help if you have ongoing depressive symptoms and thinking/executive difficulties at least 6 months after your first stroke.
New York, New YorkAges 50–79 - NCT05892965Recruiting
Instant-message online therapy for early post-stroke depression
This study tests whether brief online cognitive behavioral therapy (CBT) delivered through instant messages can reduce depression symptoms after a stroke. It may help if your depression started after your stroke and you have mild to moderately severe symptoms.
Hong KongAges 18 years+ - NCT05976152RecruitingPhase 3
Butyphthalide to improve thinking after a recent stroke
This Phase 3 study tests whether butyphthalide can help thinking and memory improve after an acute ischemic stroke. It compares people who take the study medicine versus usual care, and measures cognitive (thinking) changes over follow-up.
Dandong, LiaoningAges 60 years+ - NCT06212219Recruiting
EEG brain training to help arm recovery after stroke
This study tests whether a brain-training technique called neurofeedback can improve arm movement in people who recently had a stroke. It uses an EEG cap to measure your brain activity while you do arm exercises, helping you relearn how to move your affected arm.
ToulouseAges 18–99 - NCT06406569Recruiting
Home arm rehab technology for stroke recovery
This study tests new technologies to help people recover arm movement after a stroke. You would use special devices at home with a caregiver's help, and the team will see how well they work for you.
Singapore, SingaporeAges 21–80 - NCT06446960RecruitingPhase 3
Nerve blocks for stroke-related central pain
This study tests whether numbing the nerves in your painful arm or leg (with a nerve block) can help reduce central pain after a stroke. It aims to find out how the nerves outside your brain and spinal cord may be involved.
Boulogne-BillancourtAges 18 years+ - NCT06516588RecruitingPhase 2
Brain stimulation for memory and thinking after stroke
This trial tests if a gentle brain stimulation technique called tDCS can help improve memory and thinking in people who have had a stroke. It is for those who are still in the early recovery phase (between 10 days and 5 months after their stroke) and have some ongoing cognitive problems.
Oklahoma City, OklahomaAges 18–99 - NCT06540664Recruiting
Ear acupuncture for post-stroke insomnia
This study tests whether auricular acupuncture (using small needles on the ear) can safely and effectively improve sleep in people who developed insomnia after a stroke. It's looking for participants who have had insomnia for at least 3 months since their stroke.
Ho Chi Minh CityAges 18 years+ - NCT07691411Recruiting
Smartphone app for stroke recovery support
This study uses a smartphone app to help you manage your recovery after a stroke. It sends you quick questions and tips throughout the day to support your self-care and well-being.
Hong Kong, Hong KongAges 18 years+ - NCT06759558RecruitingPhase 2
Zuranolone for post-stroke depression
This trial tests a new medicine called zuranolone (allopregnanolone) for people with depression after a stroke. It aims to see if the drug can help improve mood when taken over a short period.
Durham, North CarolinaAges 21–65 - NCT06772194Recruiting
Taiwan Recovery After Stroke Study
This study looks at how people recover after a stroke. Researchers will check your thinking, memory, and daily function over a year to learn more about recovery patterns and help design better treatments.
TaipeiAges 18 years+ - NCT06876597Recruiting
Robotic arm therapy for stroke recovery
This trial tests a robotic arm system that combines movement and thinking tasks to help people recover arm function after a first stroke. It is for people aged 40–80 who had a stroke within the last 2 weeks to 6 months and have some arm weakness but not too severe.
FuzhouAges 40–80 - NCT07039305Recruiting
Building physical strength after stroke
This study looks at whether a specific exercise program can help people with chronic stroke (more than 6 months ago) who still have some weakness in their leg. It aims to improve walking and overall physical ability.
Charleston, South CarolinaAges 18–80 - NCT07113990Recruiting
Electroacupuncture and brain stimulation for stroke recovery
This trial tests whether combining two therapies—electroacupuncture (needles with mild electric current) and rTMS (a magnetic pulse to the brain)—can help you regain movement after a stroke. It is designed for people who had their first stroke less than 6 months ago and are still working on motor recovery.
Fuzhou, FujianAges 40–75
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Common questions
- Are there clinical trials for post-stroke depression?
- Yes. Clin2 currently lists 40 recruiting post-stroke depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post-stroke depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post-stroke depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.