Clinical trials
Post-Traumatic Stress clinical trials
Below are recruiting post-traumatic stress clinical trials, each written for real people, not researchers. We’re tracking 143 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07523685Recruiting
Vagus Nerve Stimulation for PTSD Treatment
This study tests a non-invasive device that stimulates the vagus nerve (a major nerve in your neck) to help reduce PTSD symptoms. The device is worn on the skin and may help ease trauma-related stress and anxiety.
Sunnyvale, CaliforniaAges 18–70 - NCT07632131Recruiting
Storytelling therapy to prevent PTSD after heart surgery
This study tests whether a special therapy called narrative exposure—where you talk through your surgery experience with a trained counselor—can help prevent PTSD (post-traumatic stress) in people recovering from heart surgery in the ICU. The goal is to help you process what happened so you feel less distressed afterward.
Fuzhou, FujianAges 18 years+ - NCT07644338Recruiting
Brain Stimulation for Post-Traumatic Stress Disorder
This study tests a new non-invasive brain stimulation technique called temporal interference stimulation to help reduce PTSD symptoms. If you have PTSD that's lasted at least 3 months, this trial may help you or contribute to better treatments for others.
ShanghaiAges 18–50 - NCT07490717Enrolling by invitation
Treating PTSD and opioid use in jails
This study tests new ways to screen and treat people in jail who have both post-traumatic stress disorder (PTSD) and opioid use disorder. It aims to help participants with therapy while incarcerated and after release.
Little Rock, ArkansasAges 18 years+ - NCT07455370Enrolling by invitation
Moral distress and stress study for nurses
This study looks at how work-related stress and moral challenges affect nurses. It aims to understand and improve support for nursing staff.
Phoenix, ArizonaAges Any age - NCT07313280Enrolling by invitation
PTSD and chronic pain therapy study for women
This study looks at how a psychological program can help women with chronic pain conditions linked to central sensitization (where the nervous system stays on high alert) and PTSD. It aims to reduce pain and stress symptoms.
Málaga, MálagaAges 18–65 - NCT07290127Enrolling by invitation
A computer game for mental health after emergency C-section
This trial tests if a computer game can help improve emotional well-being after an emergency cesarean birth. Participants play the game within 24 hours of delivery to see if it reduces mental health risks.
Kyoto, Sakyo-kuAges 20 years+ - NCT06823024Enrolling by invitation
Using speech patterns to predict treatment response in depression, PTSD, or bipolar disorder
This study tests if a computer algorithm can analyze your speech to predict how well you will respond to treatments like TMS or Spravato. It aims to create a simple tool that helps doctors choose the right treatment for you.
Sunnyvale, CaliforniaAges 18–68 - NCT06723834Enrolling by invitation
Service Dogs and PTSD Therapy for Military Members
This study tests if pairing a psychiatric service dog with a type of talk therapy helps military-connected people with PTSD. It’s for those who have been approved to get a service dog and are not already in the same therapy.
Tucson, ArizonaAges 18 years+ - NCT06706882Enrolling by invitation
Thinking and memory in women who have experienced partner violence
This study looks at how thinking skills like planning and memory are affected in women who have survived intimate partner violence. It may help explain how these experiences affect daily life and mental health.
Granada, GranadaAges 18–50 - NCT06215313Enrolling by invitation
Comparing two therapies for trauma memories
This study compares two types of therapy—EMDR and imagery rescripting—to help people who have upsetting memories or nightmares from past events. It's for people with depression or PTSD, and you'll need to come to therapy twice a week.
Eindhoven, North BrabantAges 18–70 - NCT06179485Enrolling by invitation
Ketamine vs. Etomidate for emergency breathing tube: long-term study
This study compares how two common medicines (ketamine and etomidate) used during emergency breathing tube placement affect long-term recovery. It is only for patients already enrolled in another related trial.
Birmingham, AlabamaAges 18 years+ - NCT05619822Enrolling by invitation
Third-steps therapy for psychosis and PTSD symptoms
This study tests a structured therapy program for people who have both psychosis symptoms and high PTSD symptoms. It aims to reduce distress from past trauma while also supporting mental health symptoms.
Pozuelo de Alarcón, MadridAges 18–65 - NCT05233111Enrolling by invitation
Exposure therapy to reduce PTSD after spinal cord injury
This trial compares a specific type of talk therapy (brief prolonged exposure) versus standard care to reduce post-traumatic stress symptoms after a spinal cord injury. If you qualify, you may get extra support targeted at PTSD symptoms during inpatient rehab.
Dallas, TexasAges 18 years+ - NCT05751473Recruiting
Reducing PTSD symptoms for first responders and frontline health workers
This study tests a way to help reduce PTSD symptoms in first responders and frontline healthcare workers. You may join a main treatment study, and some participants may also take part in follow-up questions to learn what helped.
San Diego, CaliforniaAges 18 years+ - NCT05467683Recruiting
Breathing CO2 test to predict which anxiety therapies won’t work
This study uses a controlled breathing test (inhaling CO2 or breathing faster) to see if it can predict whether exposure-based therapy will help your anxiety disorder. If you are in the right group, the results may help doctors choose more effective treatment earlier.
Boston, MassachusettsAges 18–70 - NCT05786066RecruitingPhase 2
Test whether blocking AMPA changes ketamine’s suicide relief
This study looks at whether an “AMPA receptor blocker” changes how ketamine affects suicidal thoughts in people with depression that hasn’t improved with usual treatments. If you qualify, you may receive ketamine and the study medicine, while continuing your regular mental health care.
West Haven, ConnecticutAges 21–65 - NCT05915013RecruitingPhase 1
Brain-targeting study of ketamine response in treatment-resistant depression
This early-stage study looks at how parts of brain cells respond to ketamine in people with depression who have not improved with usual antidepressants. It may help researchers find why ketamine works for some people and not others, and who might benefit.
New Haven, ConnecticutAges 18–60 - NCT06048172Recruiting
Trauma therapy for PTSD with a psychotic disorder
This trial tests if prolonged exposure therapy, a common PTSD treatment, can help people who also have a psychotic disorder (like schizophrenia or bipolar with psychosis). The goal is to reduce PTSD symptoms.
HamburgAges 18 years+ - NCT06294106Recruiting
Brain stimulation for PTSD in veterans and first responders
This study tests a new type of brain stimulation (eTMS) to help reduce PTSD symptoms in veterans and first responders. It uses an MRI to guide the treatment, and aims to see if it can improve your quality of life.
Roanoke, VirginiaAges 18–65 - NCT01730781Recruiting
PET scan study to image cannabinoid receptors in the brain
This study uses a special brain scan (PET) to measure cannabinoid receptors—areas in the brain that interact with cannabis-like chemicals. It may help researchers better understand how these receptors relate to conditions such as schizophrenia, PTSD, opioid use disorder, or early psychosis risk.
New Haven, ConnecticutAges 18–55 - NCT05565352Enrolling by invitation
Ketamine safety study for people in inpatient psychiatric care
This trial looks at whether ketamine is safe and well-tolerated for certain mental health conditions when given in a hospital setting. It may help teams better understand side effects and comfort for people who may be offered ketamine.
GdanskAges 18–90 - NCT05734547Recruiting
Support for children after trauma through parent-and-child sessions
This trial offers a structured program for children who have ongoing trauma symptoms after a scary or harmful event, with work involving both the child and a parent/caregiver. It aims to reduce post-trauma stress symptoms and help the child feel safe again.
AskerAges 7–12
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Common questions
- Are there clinical trials for post-traumatic stress?
- Yes. Clin2 currently lists 143 recruiting post-traumatic stress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post-traumatic stress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post-traumatic stress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.