Clinical trials
Post-Traumatic Stress clinical trials
Below are recruiting post-traumatic stress clinical trials, each written for real people, not researchers. We’re tracking 150 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05619822Enrolling by invitation
Third-steps therapy for psychosis and PTSD symptoms
This study tests a structured therapy program for people who have both psychosis symptoms and high PTSD symptoms. It aims to reduce distress from past trauma while also supporting mental health symptoms.
Pozuelo de Alarcón, MadridAges 18–65 - NCT05517304Recruiting
Nerve stimulation for veterans with PTSD
This study tests a device that stimulates a nerve in the neck to see if it helps with PTSD symptoms. It is for veterans who have PTSD, but have not had a brain injury or certain other health issues.
Decatur, GeorgiaAges 18–75 - NCT05491538Recruiting
Work-focused social skills training for veterans with mental illness
This study tests a program to help veterans with serious mental illness improve social skills for work and find jobs near the VA. It aims to see if the program is acceptable and feasible for participants.
Minneapolis, MinnesotaAges 18 years+ - NCT05414708Recruiting
Art therapy for veterans with PTSD symptoms
This study tests whether art therapy can improve emotional well-being in military members who have significant PTSD symptoms. You would answer questionnaires and likely take part in art-making sessions as part of the treatment being studied.
Bethesda, MarylandAges 18–64 - NCT05441280RecruitingPhase 2
Pimavanserin to improve sleep in veterans with PTSD
This Phase 2 trial studies pimavanserin, a medicine meant to improve insomnia, in veterans who also have PTSD. It may help reduce problems with falling asleep, staying asleep, or waking too early that affect daytime functioning.
Houston, TexasAges 18–64 - NCT05358067Recruiting
Testing a symptom rating tool after recent trauma
This study looks at how well a clinician’s rating scale (a questionnaire-based score) matches patients’ symptoms after a traumatic event. It may help improve how quickly and accurately symptoms are tracked in the days after trauma.
ArrasAges 18 years+ - NCT05240924Recruiting
Exposure therapy program for veterans with OCD and PTSD
This study tests whether a structured therapy approach called Exposure and Response Prevention (ERP) can improve functioning in veterans with OCD, with or without PTSD. You may be eligible if you’re receiving care through certain VA clinics or telehealth hubs and are willing to take part in ERP.
East Orange, New JerseyAges 18 years+ - NCT05219175RecruitingPhase 2
MDMA therapy for PTSD and opioid addiction after childbirth
This Phase 2 study tests whether MDMA-assisted therapy can reduce symptoms of PTSD and help with opioid use disorder in people after childbirth. You must be on a stable, low enough dose of methadone or buprenorphine and be able to follow study rules, including therapy sessions and safety monitoring.
Albuquerque, New MexicoAges 18 years+ - NCT04953273Recruiting
Case management support for adult women after violence
This study tests an organized “case management” plan for adult women who seek medical/forensic help after experiencing serious violence or threats. The goal is to improve how support and next steps are organized after the incident.
AmiensAges 18 years+ - NCT04701723Recruiting
Breathing training to help after trauma stress
This pilot study tests whether “cardiac coherence” breathing exercises can help prevent ongoing (chronic) post-traumatic stress disorder after a recent traumatic event. It’s meant for people who are newly dealing with an acute stress reaction, soon after the event.
Saint-PaulAges 18 years+ - NCT04626050Recruiting
PTSD and stress support study for healthcare workers
This study looks at psychological distress, including post-traumatic stress disorder (PTSD), in healthcare workers after work-related trauma. You may be eligible if you are an adult healthcare worker with PTSD (and otherwise stable) who can complete regular study check-ins.
New York, New YorkAges 18 years+ - NCT04519229Enrolling by invitation
Feasibility study of child-parent therapy for foster infants and toddlers
This study tests whether a therapy program called Child-Parent Psychotherapy is practical and helpful for very young children in foster care and the adults caring for them. It’s mainly a “feasibility” study, meaning it focuses on whether the program can be delivered and followed in real life.
VaxjoAges birth–6 years - NCT01627301Recruiting
Study of stress-related body overactivity in people with PTSD
This study looks at how the body’s stress system works in veterans with PTSD compared with veterans without PTSD. You may be asked about blood pressure, lifestyle, and health conditions to see whether the study measures differences that could help future treatment.
Decatur, GeorgiaAges 18–65 - NCT03887559Recruiting
Group therapy for long-lasting trauma reactions in everyday clinics
This study tests a structured group program to help people manage long-lasting trauma-related symptoms such as feeling “on edge,” avoiding reminders, upsetting memories, strong emotions, or relationship problems. It may help you learn skills and stabilize symptoms while you continue care through regular outpatient clinics.
TrondheimAges 18–75 - NCT03233646Recruiting
Retina scans in memory and nerve disorders
This study uses pictures of the back of your eye (retinal imaging) to look for differences in people with neurodegenerative diseases and compares them with people without these conditions. It may help researchers understand eye changes that could connect to brain or nerve health.
Durham, North CarolinaAges 18 years+ - NCT02560805RecruitingPhase 2
Study drugs that affect stress nerves and blood pressure in PTSD
This Phase 2 study looks at how stress-related nerve activity and a hormone called angiotensin II may be involved in PTSD, and how specific blood-pressure-related medicines affect the body. You may be eligible if you are a PTSD patient (or a matched control without PTSD) and meet safety criteria.
Decatur, GeorgiaAges 18–65 - NCT02469662Recruiting
Study of outcomes after Nexel total elbow replacement
This study looks at how well the Nexel total elbow replacement works over time for people who need an elbow replacement due to pain, damage, or instability. It may help the doctors understand which patients benefit most and what results to expect.
Golden, ColoradoAges 18 years+ - NCT01327690RecruitingEarly Phase 1
Group therapy for mental health in veterans and families
This early-stage study looks at mental health outcomes for active-duty service members, veterans, and their family members after participating in group therapy sessions. If you can follow instructions and complete consent forms, this trial may help researchers understand how group therapy affects well-being in these communities.
Santa Rosa, CaliforniaAges 18–80 - NCT05751473Recruiting
Reducing PTSD symptoms for first responders and frontline health workers
This study tests a way to help reduce PTSD symptoms in first responders and frontline healthcare workers. You may join a main treatment study, and some participants may also take part in follow-up questions to learn what helped.
San Diego, CaliforniaAges 18 years+ - NCT06048172Recruiting
Trauma therapy for PTSD with a psychotic disorder
This trial tests if prolonged exposure therapy, a common PTSD treatment, can help people who also have a psychotic disorder (like schizophrenia or bipolar with psychosis). The goal is to reduce PTSD symptoms.
HamburgAges 18 years+ - NCT07682207Recruiting
Accelerated brain stimulation for PTSD and depression
This study tests an accelerated form of brain stimulation called iTBS to see if it can help people with both PTSD and depression. It may be a good option if you have not found enough relief from your current treatments.
London, OntarioAges 18 years+ - NCT06294106Recruiting
Brain stimulation for PTSD in veterans and first responders
This study tests a new type of brain stimulation (eTMS) to help reduce PTSD symptoms in veterans and first responders. It uses an MRI to guide the treatment, and aims to see if it can improve your quality of life.
Roanoke, VirginiaAges 18–65 - NCT05915013RecruitingPhase 1
Brain-targeting study of ketamine response in treatment-resistant depression
This early-stage study looks at how parts of brain cells respond to ketamine in people with depression who have not improved with usual antidepressants. It may help researchers find why ketamine works for some people and not others, and who might benefit.
New Haven, ConnecticutAges 18–60 - NCT05786066RecruitingPhase 2
Test whether blocking AMPA changes ketamine’s suicide relief
This study looks at whether an “AMPA receptor blocker” changes how ketamine affects suicidal thoughts in people with depression that hasn’t improved with usual treatments. If you qualify, you may receive ketamine and the study medicine, while continuing your regular mental health care.
West Haven, ConnecticutAges 21–65
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Common questions
- Are there clinical trials for post-traumatic stress?
- Yes. Clin2 currently lists 150 recruiting post-traumatic stress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post-traumatic stress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post-traumatic stress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.