Clinical trials
Postoperative Pain Management clinical trials
Below are recruiting postoperative pain management clinical trials, each written for real people, not researchers. We’re tracking 126 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06839716Recruiting
Comparing a numbing gel with standard pain block after stomach cancer surgery
This study tests a gel made of ropivacaine (a numbing medicine) in a special hydrogel to see if it works as well as the standard pain block injection (TAP block) for controlling pain after minimally invasive stomach cancer surgery. The gel is applied directly near the surgical wound.
SeoulAges 20 years+ - NCT07242170Recruiting
Comparing nerve blocks for pain after knee replacement surgery
This trial tests if adding extra nerve blocks (sciatic, BiFeS, or IPACK) to the usual adductor canal block can reduce pain after total knee replacement. The goal is to find a better way to manage pain and improve recovery.
Erzincan, MerkezAges 18–75 - NCT07248072Recruiting
Nerve blocks for better recovery after knee replacement
This trial tests two types of nerve blocks—iPACK and BiFeS—to see if they help people feel better and recover faster after total knee replacement surgery. It compares adding these blocks to the usual spinal anesthesia.
ErzurumAges 18–75 - NCT07037888RecruitingPhase 4
Ketorolac for pain after hip arthroscopy
This study tests whether ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), helps manage pain after hip surgery. It may offer an opioid-sparing option for patients with femoroacetabular impingement (FAI).
Detroit, MichiganAges 18–89 - NCT07401641Recruiting
Pain control study for oral cancer surgery
This study tests two different pain medicines (dezocine or nalbuphine) combined with sufentanil to see which helps better control pain after oral cancer surgery with free flap reconstruction. It also looks at side effects and how well the transplanted tissue survives.
Guangzhou, GuangdongAges 18–70 - NCT07445854Recruiting
Sensory mapping after nerve blocks for gallbladder surgery
This trial measures how different regional anesthesia techniques affect sensation on the skin. It may help doctors understand how to better manage pain after gallbladder surgery.
Samsun, IlkadımAges 18–75 - NCT07524673Recruiting
Comparing two nerve blocks for chest surgery pain
This study tests two different numbing techniques (nerve blocks) to see which one works better for pain relief after minimally invasive chest surgery. Both methods inject medicine near nerves to reduce post-surgery pain.
Sivas, MerkezAges 18 years+ - NCT07504705Recruiting
Comparing two nerve blocks for pain after gallbladder surgery
This trial compares two types of nerve blocks (intertransverse process block and erector spinae plane block) to see which provides better pain relief after gallbladder removal surgery using small incisions (laparoscopic cholecystectomy).
Konya, KonyaAges 18 years+ - NCT07070050RecruitingPhase 4
NSAIDs after laparoscopic surgery: continuous or bolus?
This study compares giving NSAID pain relievers continuously through an IV versus as single doses (bolus) after laparoscopic surgery to find which method provides better pain relief with fewer side effects.
Moscow, Moscow OblastAges 18 years+ - NCT05705128Enrolling by invitationPhase 2/Phase 3
Dexmedetomidine to help pain after shoulder surgery
This trial studies whether dexmedetomidine can reduce pain after elective shoulder arthroscopy surgery done under general anesthesia. If you’re eligible, it may help improve postoperative comfort and reduce the need for additional pain treatment.
AsyutAges 18–60 - NCT06968065Recruiting
Pain control after minimally invasive heart surgery: nerve block vs wound injection
This study compares two ways to manage pain after minimally invasive heart surgery: a nerve block injection near the ribs or injecting numbing medicine into the wound. The goal is to find which method works better for reducing pain and your need for painkillers.
IstanbulAges 18–75 - NCT07226700RecruitingPhase 3
Suzetrigine for pain after hip replacement surgery
This study tests an investigational pain medicine called suzetrigine to see how well it controls pain after total hip replacement surgery. It is for adults 18–80 who are having a first-time hip replacement and can receive spinal anesthesia.
New York, New YorkAges 18–80 - NCT07310953Recruiting
Using new pain scales to guide rescue pain medicine after surgery
This trial tests if a simple pain scale (the NVS and PFAS) can help doctors better decide when to give extra pain medicine after surgery. It may help control pain more quickly and effectively after a procedure called VATS.
VigoAges 18 years+ - NCT07442539Recruiting
Numbing medicine for pain after hemorrhoid surgery
This trial tests a long-acting numbing medicine called liposomal bupivacaine to see if it reduces pain after hemorrhoid surgery better than standard care. It may be an option for people who are otherwise healthy and scheduled for this surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT07412223RecruitingPhase 4
Tegileridine for bowel recovery after abdominal surgery
This trial tests a painkiller called Tegileridine to see if it helps your bowels work normally again after abdominal surgery.
Guangzhou, GuangdongAges 18 years+ - NCT07185594RecruitingPhase 2/Phase 3
Study of a new pain drug after abdominal surgery
This trial tests a new medication called HRS-2129 for managing pain after abdominal surgery. It is for adults who will have moderate to severe pain after their operation, and aims to see if the drug can help control that pain safely.
Zhengzhou, HenanAges 18 years+ - NCT06710405RecruitingPhase 4
Lidocaine for pain relief after children's chest surgery
This trial tests whether giving lidocaine during surgery can reduce pain and speed up recovery in children under 7 having chest surgery with a camera. If it works, it could mean less pain and a faster return to normal after the operation.
SeoulAges 6 months–7 years - NCT07432711Recruiting
Liposomal bupivacaine for pain after lung surgery
This trial tests if a long-acting numbing medicine called liposomal bupivacaine can reduce pain after video-assisted lung surgery. It aims to help patients feel better after the procedure with less need for other painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT07441902Recruiting
Numbing medicine for lung surgery pain relief
This trial tests whether a numbing medicine (liposomal bupivacaine) injected near the ribs can reduce pain after lung surgery. If you qualify, you may experience less pain and need fewer painkillers after your operation.
Beijing, Beijing MunicipalityAges 18–64 - NCT07057557Recruiting
Aloe vera vs paraffin dressing for skin graft pain
This trial compares aloe vera dressing with paraffin tulle dressing to see which one reduces pain better at the area where a skin graft was taken. If you need a skin graft and are not allergic to either dressing, this study may help find a gentler way to manage your pain.
Lahore, Punjab ProvinceAges 18–60 - NCT06757075RecruitingPhase 4
Managing pain after children's dental surgery
This study tests different ways to manage pain in young children after dental surgery done under general anesthesia. It aims to find the best method to keep children comfortable and reduce discomfort.
Brighton, MassachusettsAges 4–6 - NCT06559215RecruitingPhase 2
Pain management with Exparel after knee surgery in teens
This trial is testing a long-acting numbing medicine called Exparel to see how well it controls pain after a specific knee surgery (MPFL reconstruction) in teens and young adults. It may help reduce the need for strong painkillers after the operation.
Frisco, TexasAges 13–21 - NCT06020677Recruiting
Latinx children and surgery study
This study looks at how Latinx families manage their child's pain after outpatient surgery. It aims to improve care for Spanish-speaking families.
Orange, CaliforniaAges 2–7 - NCT03675386Recruiting
Help reducing opioid use after surgery for chronic pain
This trial tests a program to help people with long-term (chronic) pain use less opioid medicine after surgery. It may help you reduce opioid doses while still managing your pain.
Toronto, OntarioAges 18 years+
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Common questions
- Are there clinical trials for postoperative pain management?
- Yes. Clin2 currently lists 126 recruiting postoperative pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.