Clinical trials
Postoperative Pain Management clinical trials
Below are recruiting postoperative pain management clinical trials, each written for real people, not researchers. We’re tracking 122 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07362589Enrolling by invitation
Does pain education before knee or hip replacement help?
This study tests whether a special education session before knee or hip replacement surgery can help reduce anxiety, pain, and the need for pain medicine after surgery. If you are scheduled for joint replacement and can take part in a short learning session, you may be eligible.
Istanbul, KayişdağiAges 18 years+ - NCT07720739Recruiting
Adding morphine to a spine block for belly surgery pain
This study tests whether adding a small dose of morphine to a numbing injection near the spine (called erector spinae plane block) provides better pain relief after midline belly surgery. It may help reduce the need for other pain medicines and improve recovery.
SohagAges 18–60 - NCT07571252RecruitingPhase 4
Pain Relief Before Jaw Surgery: A Study
This study tests whether taking pain medicine before jaw surgery (orthognathic surgery) helps reduce pain after the procedure. If you're having jaw surgery, this trial may help doctors understand the best way to manage your pain.
San JuanAges 21–65 - NCT07311902Recruiting
Comparing two blocks for pain after hernia repair
This trial compares two types of nerve blocks (M-Tapa block and TAP block) to see which one works better for controlling pain after open inguinal hernia repair. It may help find a better way to manage pain after surgery.
ErzurumAges 18–65 - NCT07208799RecruitingPhase 2
Steroid comparison for jaw fracture recovery
This trial compares two steroid medicines (dexamethasone and methylprednisolone) to see which one better reduces swelling, pain, and other symptoms after surgery for a broken lower jaw near the chin. It could help you recover faster and with less discomfort.
Multan, Punjab ProvinceAges 18–40 - NCT07672015RecruitingPhase 4
Testing a new pain drug in surgery patients at risk for opioid dependence
This trial tests a new painkiller called suzetrigine for post-surgery pain. It's designed for people whose medical records suggest they may have a higher chance of needing strong painkillers (opioids) long after surgery. We want to see if suzetrigine works better at preventing that.
La Jolla, CaliforniaAges 18 years+ - NCT06926322Enrolling by invitation
Treating dead baby molars with special medicines
This study tests different medicines to treat dead (necrotic) baby molars in children. The goal is to safely clean the infection and save the tooth so it can stay until it falls out naturally.
CairoAges 4–8 - NCT07123740Recruiting
Pain relief after liver donor surgery: two methods compared
This study compares two ways to control pain after surgery for living liver donors. It tests if one method works better than the other, which could help you recover more comfortably.
Altındağ, AnkaraAges 18–65 - NCT06639022Recruiting
Pain relief after cervical spine surgery
This study compares two types of nerve blocks to see which provides better pain relief after neck surgery. It looks for patients scheduled for a specific neck procedure called anterior cervical discectomy.
Altındağ, AnkaraAges 18–80 - NCT07147062Recruiting
Pain relief after hernia surgery in children
This trial compares two types of pain blocks (rectus sheath block or caudal epidural block) used in children having a specific hernia surgery. It aims to see which block works better for controlling pain after the procedure.
Altındağ, AnkaraAges 1–8 - NCT05985772Recruiting
Surgery vs no surgery for a type of knee tear
This trial compares surgery with non-surgical treatment for a specific tear in the knee's meniscus, the posterior-medial root tear. It aims to find out which approach works better and helps you decide with your doctor.
Chicago, IllinoisAges 18 years+ - NCT07442188Recruiting
Comparing two numbing blocks for hernia surgery pain
This trial compares two types of numbing injections (nerve blocks) given before hernia surgery to see which one works better for pain after the operation. The blocks target muscles around the belly area to help you feel less pain and recover more comfortably.
Ankara, Yenimahalle\AnkaraAges 18–65 - NCT07388953Recruiting
Nerve block for better pain relief after colon surgery
This study tests adding a special nerve block (peripheral autonomic block) to a standard abdominal wall block to see if it provides better pain relief after minimally invasive left-sided colon surgery. It may help patients experience less pain and use fewer pain medications.
Belo Horizonte, Minas GeraisAges 18–80 - NCT07867951Recruiting
Pain after two root canal medicines
This study compares two medicines placed inside a tooth during root canal treatment to see which one reduces pain better afterward. It may help people with an infected tooth causing pain.
Swāt, KpkAges 16–50 - NCT07818954Recruiting
Nerve block near the belly for gallbladder surgery
This study tests a numbing injection (called a subcostal TAP block) given near the belly to see if it affects brain activity during gallbladder surgery. It may help improve pain control and anesthesia care.
IstanbulAges 18 years+ - NCT07716540Recruiting
Pain relief injection for hip fracture surgery
This study tests whether a special numbing injection (deep iliacus plane block) can better control pain after hip fracture surgery. If you're having hip surgery under spinal anesthesia, researchers want to see if this extra block helps you recover with less pain.
Istanbul, IstanbulAges 18 years+ - NCT07626684Enrolling by invitation
Ice Pack After Minimally Invasive Hysterectomy Surgery
This study tests whether applying ice packs to the abdomen after a minimally invasive hysterectomy (removal of the uterus through the vagina) helps reduce pain and speed recovery. You would be randomly assigned to either receive ice pack treatment or standard care.
MuğlaAges 48–70 - NCT07524387Recruiting
Nerve blocks for better leg strength after knee replacement
This study compares two types of numbing injections (nerve blocks) used during knee replacement surgery to see which one helps your thigh muscle recover strength faster. Both are standard care options; the trial tests which works better for early movement after surgery.
Ichinomiya, Aichi-kenAges 20 years+ - NCT07423650RecruitingPhase 4
Continuous Nefopam infusion after pancreas surgery
This trial tests if giving a steady dose of a painkiller called nefopam through an IV can help manage pain after a Whipple procedure (pancreatoduodenectomy). It aims to see if this approach reduces the need for other pain medications and improves recovery.
Cluj-Napoca, ClujAges 18–80 - NCT07348627RecruitingPhase 3
Opioid-free hip replacement study
This trial tests if using fewer opioids after hip replacement surgery can still control pain well. It uses a specific type of hip replacement called anterior total hip arthroplasty and aims to help patients recover with less reliance on strong pain medicines.
Atlanta, GeorgiaAges 18 years+ - NCT06843174RecruitingPhase 4
Methadone for pain during and after spine surgery
This trial tests if giving a single dose of methadone right before and during spine surgery can help manage pain better. If it works, you might need fewer other pain medicines after surgery.
Toronto, OntarioAges 18–65 - NCT06913920Recruiting
Comparing therapies for hand swelling and pain after wrist fracture surgery
This trial tests whether using mechanical devices (like compression or massage) reduces swelling and pain better than standard care after wrist fracture surgery. It may help you recover hand function more comfortably.
CairoAges 18–65 - NCT07060495RecruitingPhase 3
RADA16 gel for pain after adult tonsillectomy
This trial tests a new gel (RADA16) placed on the tonsil area after surgery to see if it helps reduce pain and speed healing. It is for adults having a standard tonsillectomy.
Livingston, New JerseyAges 18 years+ - NCT06384456RecruitingPhase 4
TXA vs Placebo for Pain After Wrist Surgery
This study tests if tranexamic acid (TXA), a medicine used to reduce bleeding, can help lessen pain right after wrist fracture surgery. You may be able to join if you had breast cancer and radiation at least a year ago, are not currently on active cancer treatment, and don't take blood thinners or daily strong pain pills.
Toronto, OntarioAges 18 years+
Hear when a new Postoperative Pain Management trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for postoperative pain management?
- Yes. Clin2 currently lists 122 recruiting postoperative pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.