Clinical trials
Posttraumatic Stress Symptom clinical trials
Below are recruiting posttraumatic stress symptom clinical trials, each written for real people, not researchers. We’re tracking 42 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05700201Recruiting
Study of heart health in adults with trauma symptoms
This study looks at how trauma-related symptoms (like PTSD symptoms) may affect heart health. You may be asked to do light activity—so your study team can see how your body responds.
Fort Lauderdale, FloridaAges 18 years+ - NCT05737693RecruitingPhase 2
Ketamine plus weekly therapy for severe PTSD
This study tests whether adding ketamine to a structured, one-week psychological therapy program can reduce severe PTSD symptoms. It may help people who have had PTSD for a long time and still feel very affected.
New Haven, ConnecticutAges 21–70 - NCT05776056RecruitingPhase 4
Methylphenidate for PTSD and thinking problems in Veterans
This study tests whether methylphenidate (a stimulant medicine) can improve PTSD symptoms and help with memory or thinking problems people report. It may help Veterans who have both PTSD and recent cognitive difficulties.
Birmingham, AlabamaAges 18–65 - NCT05837845RecruitingPhase 2
MDMA plus therapy versus therapy alone for severe PTSD
This Phase 2 study compares MDMA-assisted Cognitive Processing Therapy (a structured talk-therapy) to Cognitive Processing Therapy alone for Veterans with severe PTSD. It aims to see whether adding MDMA helps reduce PTSD symptoms and improve recovery.
Palo Alto, CaliforniaAges 18 years+ - NCT05843695Recruiting
Therapy study for PTSD and anxiety in veterans
This trial tests a psychotherapy approach to help veterans and service members who have PTSD and/or anxiety disorders. You may be randomly assigned to different therapy conditions, and the study aims to improve quality of life and reduce anxiety and PTSD symptoms.
Houston, TexasAges 18 years+ - NCT06047691Recruiting
Couples therapy for PTSD in military couples
This study tests whether intensive couples therapy helps military couples dealing with PTSD, compared to a relationship education class. If you are a service member or veteran with PTSD and your partner is willing to join, this trial might offer a way to improve your relationship and PTSD symptoms together.
San Antonio, TexasAges 18 years+ - NCT06127342Recruiting
Exercise and emotional learning for PTSD
This study tests whether exercise can help people with PTSD learn to feel safer in their bodies. You will do some exercise sessions and emotional learning tasks, and have an MRI brain scan to see how your brain changes.
Lexington, KentuckyAges 18–64 - NCT06193161Recruiting
Prolonged Exposure Therapy for PTSD in Immigrants
This trial tests prolonged exposure therapy for immigrants in Sweden who have PTSD. You will receive this online therapy to see if it helps reduce trauma symptoms.
SolnaAges 18 years+ - NCT06348472Recruiting
Biomarkers and PTSD psychotherapy response
This study is looking at whether certain biomarkers in your blood (related to inflammation and the oxytocin system) can predict how well you respond to trauma-focused psychotherapy. It may help find better ways to personalize PTSD treatment.
Hod HaSharonAges 18–80 - NCT06429293Recruiting
Talk therapy for PTSD and heart health
This study tests whether cognitive behavioral therapy (a type of talk therapy) can improve heart health in people with PTSD. If you have PTSD and are at risk for or have heart disease, you may be able to join.
Boston, MassachusettsAges 18–65 - NCT06535516Recruiting
Supporting youth and families after tough experiences
This study tests a program to help youth ages 10-15 who have faced child maltreatment, like abuse or neglect. It aims to build resilience in both the youth and their family.
Rochester, New YorkAges 10–15 - NCT06573970RecruitingPhase 4
Atomoxetine for PTSD and executive function in veterans
This trial tests if the medication atomoxetine can improve thinking and memory in veterans with PTSD and attention difficulties. It may help those who have not responded fully to other treatments.
Charleston, South CarolinaAges 18–75 - NCT06968832Recruiting
Prolonged therapy for PTSD and substance use
This trial tests a therapy that helps people with both post-traumatic stress disorder (PTSD) and a substance use disorder (SUD). You'll receive extended therapy sessions to reduce PTSD symptoms and support your recovery from substance use, while continuing your current substance use treatment.
Jacksonville, FloridaAges 18 years+ - NCT07238192Recruiting
Testing a therapy to reduce suicide risk in veterans with PTSD
This trial is testing whether a therapy called Cognitive Processing Therapy (CPT), given in an intensive format, can reduce suicide risk in veterans and active duty service members with PTSD. It aims to see if this approach is more effective than standard care at preventing suicidal thoughts and behaviors.
Fort Hood, TexasAges 18 years+ - NCT07250061Recruiting
Self-help PTSD program for women veterans
This study tests a self-guided program to help women veterans with PTSD. You would work through coping skills on your own, with support from a group of other women veterans.
Boston, MassachusettsAges 18 years+ - NCT05427500Enrolling by invitationPhase 3
Nerve block treatment for PTSD with strong stress-and-alertness symptoms
This Phase 3 study tests whether a procedure called a stellate ganglion block can reduce PTSD symptoms, especially feeling highly “on edge” (hyperarousal). You may join if you have PTSD despite appropriate usual treatments and are able to go through the procedure safely.
Ottawa, OntarioAges 18–69 - NCT03887559Recruiting
Group therapy for long-lasting trauma reactions in everyday clinics
This study tests a structured group program to help people manage long-lasting trauma-related symptoms such as feeling “on edge,” avoiding reminders, upsetting memories, strong emotions, or relationship problems. It may help you learn skills and stabilize symptoms while you continue care through regular outpatient clinics.
TrondheimAges 18–75 - NCT07071350RecruitingPhase 2/Phase 3
Optimizing heart rate for persistent concussion symptoms in military veterans
This trial tests a treatment designed to improve heart rate variability, which may help reduce long-term concussion symptoms like headaches, dizziness, and trouble sleeping. It is for military veterans who have had a mild concussion more than a year ago and still have ongoing symptoms.
Richmond, VirginiaAges 18 years+
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Common questions
- Are there clinical trials for posttraumatic stress symptom?
- Yes. Clin2 currently lists 42 recruiting posttraumatic stress symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a posttraumatic stress symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a posttraumatic stress symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.