Clinical trials
Pre Diabetes clinical trials
Below are recruiting pre diabetes clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06555952Recruiting
Grape seed extract for blood pressure and heart health
This trial tests whether a grape seed extract can help lower blood pressure in people with mildly high blood pressure and slightly elevated blood sugar. It's designed for adults aged 40-60 who are not on blood pressure or diabetes medications.
Chicago, IllinoisAges 40–60 - NCT06446531RecruitingPhase 1
Preventing diabetes progression in Hispanic adults
This trial tests if a medication can prevent or slow the progression from prediabetes to type 2 diabetes and reduce heart risk. It is for Hispanic adults who are overweight and have prediabetes.
San Antonio, TexasAges 18 years+ - NCT05585190Recruiting
Sit-stand desk study for people at diabetes risk
This trial tests whether using a sit-stand desk at work helps people who are overweight and at risk for diabetes. Participants may be asked to change how much they sit during the workday to improve health markers.
Milwaukee, WisconsinAges 18–79 - NCT02915198RecruitingPhase 4
Metformin for prediabetes to reduce heart and blood-vessel events
This trial tests whether taking metformin in people with prediabetes can lower the chance of future heart attack, stroke, or other blood-vessel problems. You may be a good fit if you have prediabetes plus existing cardiovascular disease or significant blood-vessel disease.
Phoenix, ArizonaAges 18 years+ - NCT05051436RecruitingPhase 4
Testing mirabegron and tadalafil to improve sugar control
This study looks at whether mirabegron and tadalafil can improve blood sugar control in people with prediabetes. It may help determine if these medicines can slow the move from prediabetes toward diabetes.
Lexington, KentuckyAges 35–65 - NCT06694155Recruiting
Whey protein and blood sugar study for pre-diabetes and diabetes
This study tests whether drinking whey protein can help control blood sugar in people with pre-diabetes or mild diabetes. If you qualify, you'll wear a continuous glucose monitor and keep a food journal for two weeks.
Little Rock, ArkansasAges 50–70 - NCT07241221Recruiting
Myo-inositol supplement for diabetes in pregnancy
This study tests whether taking a supplement called myo-inositol (a natural vitamin-like substance) during pregnancy can help manage blood sugar in women with type 2 diabetes. It may improve outcomes for you and your baby.
Singapore, SingaporeAges 21–45 - NCT07470320Recruiting
Placenta study in healthy and complicated pregnancies
This study looks at how the placenta works in healthy pregnancies and in pregnancies with conditions like pre-eclampsia, gestational diabetes, or fetal growth restriction. It may help find new ways to detect or treat these problems.
OxfordAges 18 years+ - NCT04834518Recruiting
Screening children for early signs of type 1 diabetes
This study checks for specific blood markers (“islet autoantibodies”) to find children who may be at risk for developing type 1 diabetes later, before symptoms start. It’s mainly for children who have no known diabetes yet.
BeershebaAges 9 months–5 years - NCT07336316Enrolling by invitation
Heart MRI study for early heart failure with preserved pump function
This trial uses advanced MRI scans to study early signs of heart failure in people whose heart pumps normally but who have risk factors like diabetes, high blood pressure, or obesity. It aims to improve detection and understanding of this condition.
Ages Any age - NCT06892483Recruiting
Breast milk changes after one exercise session
This trial looks at how your breast milk changes after you do one exercise session. It compares milk from people who exercise regularly with those who don't, to see if exercise affects milk composition.
Rochester, MinnesotaAges 18–45 - NCT07263490Recruiting
Pre-eclampsia Risk in Egg Recipients Study
This study looks at whether women who become pregnant after receiving donated eggs have a higher risk of developing pre-eclampsia (a serious blood pressure condition) during pregnancy. It aims to understand risks so doctors can better support pregnant women.
CopenhagenAges 18 years+ - NCT06191094Enrolling by invitationPhase 4
Vabysmo before eye surgery for bleeding in diabetes
This trial tests if an injection of Vabysmo (faricimab) given before surgery can help people with eye bleeding from diabetic retinopathy. It aims to reduce blood in the eye and improve surgery outcomes.
Aurora, ColoradoAges 18 years+ - NCT06802861Recruiting
Aspirin metabolism in pregnant women at risk of pre-eclampsia
This study looks at how pregnant women at risk of pre-eclampsia process aspirin and how it affects their metabolism. Researchers will use blood and urine tests, along with body measurements and surveys, to learn more about how aspirin can help prevent pre-eclampsia.
Knoxville, TennesseeAges 18–45 - NCT06945406RecruitingPhase 1
Study of an investigational drug for diabetes
This trial tests a new medicine, LY4057996, in people with type 1 or type 2 diabetes and in healthy volunteers. It aims to see if the drug is safe and how it works in the body.
NeussAges 18 years+ - NCT06759701RecruitingEarly Phase 1
Weight loss drug before prostate cancer surgery pilot study
This study tests if taking tirzepatide (a weight loss medicine) before prostate removal surgery is safe and helpful for overweight men with intermediate-risk prostate cancer. It aims to see if losing weight can improve surgery outcomes.
Houston, TexasAges 18 years+ - NCT07106879Recruiting
Pre-screening for future metabolic and psychiatric studies
This study does not test a new treatment. It is a pre-screening program to see if you might qualify for future clinical trials on metabolic conditions (like diabetes or weight issues) or psychiatric health (like depression or anxiety). You will be asked some questions and may do some basic health checks to see which future trials could be a good fit for you.
Brooklyn, New YorkAges 18 years+
Hear when a new Pre Diabetes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pre diabetes?
- Yes. Clin2 currently lists 65 recruiting pre diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pre diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pre diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.