Clinical trials
Prediabetes / Type 2 Diabetes clinical trials
Below are recruiting prediabetes / type 2 diabetes clinical trials, each written for real people, not researchers. We’re tracking 73 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05681468Recruiting
Ketogenic diet trial for blood sugar and inflammation outcomes
This study compares two versions of a ketogenic (very low-carb) diet to see how they affect blood sugar control and inflammation. It may help people with overweight or obesity who have pre-diabetes-level blood sugar understand which fat sources work better.
Edmonton, AlbertaAges 18–70 - NCT04943861Recruiting
Study on HIV and food insecurity support
This study is looking at food insecurity in adults living with HIV. It may help improve understanding of the barriers to healthy living and guide better support for people affected by HIV.
Winston-Salem, North CarolinaAges 18 years+ - NCT03568630Recruiting
Blood tests to study early pancreatic cancer risk
This study looks at blood “markers” to find early signs or higher risk for pancreatic cancer. You may join if you have certain risk factors (like new diabetes, pancreatic cysts/pancreatitis, or a strong family history) and can come to Omaha for blood draws twice a year.
Omaha, NebraskaAges 19 years+ - NCT07688694Enrolling by invitation
Testing a legume-based supplement for blood sugar control
This study tests a supplement made from legume seed coats that may help control blood sugar. It is open to healthy adults, people at risk for diabetes, or those already diagnosed with type 2 diabetes.
Mysore, KarnatakaAges 20–60 - NCT07803809RecruitingPhase 1
MWN105 injection for overweight and obesity
This study tests an investigational injection called MWN105 in people who are overweight or obese but do not have diabetes. The goal is to see if it is safe and helps with weight loss.
Kunming, YunnanAges 18–50 - NCT03925714RecruitingPhase 3
Testing a gene-related approach in people with prediabetes
This trial studies how changes involving p53 and SIRT1 may affect health in people with prediabetes. It may help researchers find better ways to stop or slow progression to type 2 diabetes.
CairoAges 18 years+ - NCT07736547Enrolling by invitation
AI-guided supplement for weight loss
This study tests a nutritional supplement (guided by your gut bacteria) to help with weight loss, along with lifestyle advice. It might be a good fit if you are overweight but not diabetic and have not used weight-loss medications recently.
IstanbulAges 18–65 - NCT07376655Recruiting
Test of a health app for lifestyle and wellbeing
This study tests whether using the Thrive AI Health app can help improve daily habits and quality of life for people at high risk for chronic diseases like diabetes. If you're 40 or older and have a higher BMI or diabetes risk, you might be eligible.
New Haven, ConnecticutAges 40 years+ - NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
Anniston, AlabamaAges 18 years+ - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT07075588Recruiting
Food and coaching to lower blood pressure for Black and Hispanic adults
This study tests a program that helps people manage their blood pressure by offering healthy food choices, personal diet coaching, and text messages that match your culture. It's for Black/African American or Hispanic/Latino adults living in certain low-income areas of Maryland.
Baltimore, MarylandAges 21–70 - NCT07808723Recruiting
Family program to prevent type 2 diabetes in African American and Hispanic households
This 12-week program helps African American and Hispanic families in Georgia lower their risk of type 2 diabetes by making healthy changes together. If you have prediabetes or are at risk, you and your teenager (ages 12-17) can join to learn about nutrition, exercise, and better health habits.
Atlanta, GeorgiaAges 12 years+ - NCT07378891Enrolling by invitation
AI eye screening for early diabetic retinopathy
This study uses artificial intelligence (AI) to look at photos of the back of your eye (retina) to find early signs of diabetic eye disease. It aims to catch problems before they worsen, so you can get treatment sooner.
TübingenAges 18–80 - NCT06921902Recruiting
Study of blood sugar patterns in people with and without prediabetes
This study monitors blood sugar levels and patterns in people with and without prediabetes. It uses a continuous glucose monitor to see how blood sugar varies during daily life, and helps researchers understand early signs of blood sugar problems. You may be eligible if you do not have diabetes and are not on special diets or certain medications.
Bend, OregonAges 18 years+ - NCT04607096Recruiting
Intermittent fasting to improve insulin in prediabetes or early type 2
This study tests whether intermittent fasting can improve how your body releases and uses insulin if you have prediabetes or early type 2 diabetes. It may help your blood sugar control without using insulin.
BerlinAges 18–70 - NCT05740514Recruiting
Exercise program study for adults with type 1 diabetes
This study looks at how an exercise program affects “healthy outcomes” in people with type 1 diabetes. You might be invited if you are the right age, generally less active, and have a safe health profile for exercising.
Hamilton, OntarioAges 18–65 - NCT06252038Recruiting
Rural Diabetes Prevention Program
This study tests a diabetes prevention program designed for people in rural Kansas. It helps those with pre-diabetes make healthy lifestyle changes to prevent or delay type 2 diabetes.
Kansas City, KansasAges 18 years+ - NCT07423065Recruiting
Continuous glucose monitor for prediabetes and weight loss
This study tests whether wearing a continuous glucose monitor (a small sensor on your skin that tracks your blood sugar) can help people with prediabetes and obesity better control their blood sugar and lose weight. You will be asked to wear the device for several days to see how your glucose levels change throughout the day.
IzolaAges 18–70 - NCT03308773Enrolling by invitation
Prevention program for people at risk of type 2 diabetes
This trial looks at a personalized prevention approach for people who are at risk of developing type 2 diabetes. It may help by targeting your specific health factors before diabetes starts.
Ages 18–100 - NCT04634591Recruiting
Weight-loss surgery study for people with severe obesity
This trial studies bariatric (weight-loss) surgery and how well it helps people reach and keep a healthier weight. You may qualify if you have severe obesity and have not been able to maintain weight loss with other attempts, and if you can safely follow the study plan.
Bialystok, Podlaskie VoivodeshipAges 18 years+ - NCT07389005Recruiting
Exercise timing for people with prediabetes
This study tests whether the time of day you exercise affects blood sugar control in people with prediabetes. It may help find the best exercise schedule for your body's internal clock.
DüsseldorfAges 19–75 - NCT07599072Recruiting
Blood Sugar Monitoring Study for Prediabetes
This study tracks how blood sugar levels change in people with prediabetes (higher-than-normal blood sugar but not yet diabetes). Researchers will use a small sensor to monitor your blood sugar and help understand what affects it, which could help prevent or delay type 2 diabetes.
KyivAges 18 years+ - NCT07403604RecruitingPhase 1
Lowering Insulin to Reduce Fat Buildup in the Liver
This study tests if lowering insulin levels can reduce fat buildup in the liver for people with a fatty liver condition called MASLD. It's looking for adults who are overweight and have early signs of insulin resistance but not diabetes.
New York, New YorkAges 18–65 - NCT06440395Recruiting
Healthy eating and exercise program for prediabetes
This study tests a program called Small Steps for Big Changes, which helps people with prediabetes adopt healthier habits. The goal is to see if it works in community settings like YMCAs.
Edmonton, AlbertaAges 18 years+
Hear when a new Prediabetes / Type 2 Diabetes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for prediabetes / type 2 diabetes?
- Yes. Clin2 currently lists 73 recruiting prediabetes / type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prediabetes / type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prediabetes / type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.