Clinical trials
Prediabetes / Type 2 Diabetes clinical trials
Below are recruiting prediabetes / type 2 diabetes clinical trials, each written for real people, not researchers. We’re tracking 75 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07602023Recruiting
Fat Response and Diabetes Risk Study
This study looks at how your body processes fat after eating and measures certain blood markers to understand who might develop diabetes or complications. You'll eat a high-fat meal and have blood drawn to help doctors identify early warning signs.
Ferrara, FerraraAges 50–70 - NCT07598773Enrolling by invitation
Continuous glucose monitoring study for prediabetes and type 2 diabetes
This study asks you to wear a glucose monitor and smart ring for several months to help researchers understand how blood sugar changes throughout the day in people with prediabetes or type 2 diabetes. The goal is to learn how lifestyle and medications affect blood sugar control.
San Francisco, CaliforniaAges 18 years+ - NCT07354386Enrolling by invitation
Dried whole fruits and diabetes metabolism study
This trial tests if eating dried whole fruits can improve metabolism in people with untreated pre-diabetes or type 2 diabetes, with or without fatty liver disease. It may help you understand if a simple dietary change can support your health.
Winnipeg, ManitobaAges 18–74 - NCT06804187Enrolling by invitation
Sweet taste and type 2 diabetes study
This study looks at how sweet taste is sensed in people with type 2 diabetes, prediabetes, or no diabetes. It involves taste tests and possibly brain scans (MRI) to help understand why people with diabetes may perceive sweetness differently.
Nottingham, East MidlandsAges 18–60 - NCT05730582Enrolling by invitation
Improve diabetes screening by using health outreach from records
This trial looks at whether outreach messages sent using your electronic health record can help more adults get diabetes screening. It’s designed for people who are at risk for diabetes but are not already in the clinic’s diabetes registry.
Dallas, TexasAges 18–75 - NCT07688694Enrolling by invitation
Testing a legume-based supplement for blood sugar control
This study tests a supplement made from legume seed coats that may help control blood sugar. It is open to healthy adults, people at risk for diabetes, or those already diagnosed with type 2 diabetes.
Mysore, KarnatakaAges 20–60 - NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
Anniston, AlabamaAges 18 years+ - NCT03925714RecruitingPhase 3
Testing a gene-related approach in people with prediabetes
This trial studies how changes involving p53 and SIRT1 may affect health in people with prediabetes. It may help researchers find better ways to stop or slow progression to type 2 diabetes.
CairoAges 18 years+ - NCT07736547Enrolling by invitation
AI-guided supplement for weight loss
This study tests a nutritional supplement (guided by your gut bacteria) to help with weight loss, along with lifestyle advice. It might be a good fit if you are overweight but not diabetic and have not used weight-loss medications recently.
IstanbulAges 18–65 - NCT07376655Recruiting
Test of a health app for lifestyle and wellbeing
This study tests whether using the Thrive AI Health app can help improve daily habits and quality of life for people at high risk for chronic diseases like diabetes. If you're 40 or older and have a higher BMI or diabetes risk, you might be eligible.
New Haven, ConnecticutAges 40 years+ - NCT07075588Recruiting
Food and coaching to lower blood pressure for Black and Hispanic adults
This study tests a program that helps people manage their blood pressure by offering healthy food choices, personal diet coaching, and text messages that match your culture. It's for Black/African American or Hispanic/Latino adults living in certain low-income areas of Maryland.
Baltimore, MarylandAges 21–70 - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT05117424Recruiting
Study of metabolism and plaque changes in heart disease
This trial looks at how treating or managing conditions like diabetes, prediabetes, obesity, kidney disease, or high cholesterol affects artery plaque over time. It may help researchers find ways to slow plaque buildup and related heart risks.
ShanghaiAges 18–80 - NCT07378891Enrolling by invitation
AI eye screening for early diabetic retinopathy
This study uses artificial intelligence (AI) to look at photos of the back of your eye (retina) to find early signs of diabetic eye disease. It aims to catch problems before they worsen, so you can get treatment sooner.
TübingenAges 18–80 - NCT06921902Recruiting
Study of blood sugar patterns in people with and without prediabetes
This study monitors blood sugar levels and patterns in people with and without prediabetes. It uses a continuous glucose monitor to see how blood sugar varies during daily life, and helps researchers understand early signs of blood sugar problems. You may be eligible if you do not have diabetes and are not on special diets or certain medications.
Bend, OregonAges 18 years+ - NCT04607096Recruiting
Intermittent fasting to improve insulin in prediabetes or early type 2
This study tests whether intermittent fasting can improve how your body releases and uses insulin if you have prediabetes or early type 2 diabetes. It may help your blood sugar control without using insulin.
BerlinAges 18–70 - NCT06417840Recruiting
Testing a plant compound for blood sugar in pre-diabetes
This study tests whether a natural compound from plants can help lower blood sugar levels in people with pre-diabetes. It focuses on Asian Indian adults who are overweight and have slightly high blood sugar.
New DelhiAges 18–50 - NCT04201600Recruiting
Study how blood sugar swings affect thinking in prediabetes
This study looks at how “blood sugar variability” (how much glucose levels bounce around) may affect thinking and memory in people with prediabetes. You may be eligible if you’re older and don’t already have diabetes or conditions that can strongly affect the brain or blood vessels.
Baltimore, MarylandAges 50 years+ - NCT05740514Recruiting
Exercise program study for adults with type 1 diabetes
This study looks at how an exercise program affects “healthy outcomes” in people with type 1 diabetes. You might be invited if you are the right age, generally less active, and have a safe health profile for exercising.
Hamilton, OntarioAges 18–65 - NCT06252038Recruiting
Rural Diabetes Prevention Program
This study tests a diabetes prevention program designed for people in rural Kansas. It helps those with pre-diabetes make healthy lifestyle changes to prevent or delay type 2 diabetes.
Kansas City, KansasAges 18 years+ - NCT07423065Recruiting
Continuous glucose monitor for prediabetes and weight loss
This study tests whether wearing a continuous glucose monitor (a small sensor on your skin that tracks your blood sugar) can help people with prediabetes and obesity better control their blood sugar and lose weight. You will be asked to wear the device for several days to see how your glucose levels change throughout the day.
IzolaAges 18–70 - NCT03308773Enrolling by invitation
Prevention program for people at risk of type 2 diabetes
This trial looks at a personalized prevention approach for people who are at risk of developing type 2 diabetes. It may help by targeting your specific health factors before diabetes starts.
Ages 18–100 - NCT04634591Recruiting
Weight-loss surgery study for people with severe obesity
This trial studies bariatric (weight-loss) surgery and how well it helps people reach and keep a healthier weight. You may qualify if you have severe obesity and have not been able to maintain weight loss with other attempts, and if you can safely follow the study plan.
Bialystok, Podlaskie VoivodeshipAges 18 years+ - NCT06440395Recruiting
Healthy eating and exercise program for prediabetes
This study tests a program called Small Steps for Big Changes, which helps people with prediabetes adopt healthier habits. The goal is to see if it works in community settings like YMCAs.
Edmonton, AlbertaAges 18 years+
Hear when a new Prediabetes / Type 2 Diabetes trial opens
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Common questions
- Are there clinical trials for prediabetes / type 2 diabetes?
- Yes. Clin2 currently lists 75 recruiting prediabetes / type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prediabetes / type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prediabetes / type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.