Clinical trials
Prediabetes / Type 2 Diabetes clinical trials
Below are recruiting prediabetes / type 2 diabetes clinical trials, each written for real people, not researchers. We’re tracking 75 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07448974RecruitingPhase 3
Vitamin D for Preventing Type 2 Diabetes
This study tests if taking extra vitamin D can help people with prediabetes keep their blood sugar in a healthy range and lower the chance of developing type 2 diabetes. Participants will take high-dose or standard vitamin D and be monitored for about 2 years.
Boston, MassachusettsAges 30–74 - NCT07474376Recruiting
Audio diary app for diabetes with other health conditions
This trial tests if using an audio diary app can help people with diabetes and at least one other health condition, like obesity or heart failure, manage their health better. You can join if you have a smartphone and can use the app and online surveys.
Atlanta, GeorgiaAges 65 years+ - NCT07670416RecruitingPhase 3
A study of enicepatide for people with obesity or overweight
This trial tests if enicepatide can help people with obesity or overweight lose weight, including those with or without type 2 diabetes. It aims to see if the drug is safe and effective.
Zhengzhou, HenanAges 18 years+ - NCT07441655Recruiting
Family program for healthy habits and preventing diabetes
This study helps Black parents with prediabetes and their children make healthy lifestyle changes together to prevent diabetes. It lasts about 20 months and involves physical activity and nutrition support.
Albany, GeorgiaAges 18 years+ - NCT07743021Recruiting
Blood sample study for better health screening
This study collects blood samples and health information over time to improve early detection of diseases. It may help researchers find ways to prevent serious conditions.
BalatonfüredAges 40 years+ - NCT05681468Recruiting
Ketogenic diet trial for blood sugar and inflammation outcomes
This study compares two versions of a ketogenic (very low-carb) diet to see how they affect blood sugar control and inflammation. It may help people with overweight or obesity who have pre-diabetes-level blood sugar understand which fat sources work better.
Edmonton, AlbertaAges 18–70 - NCT03455868Recruiting
Bone health check after bariatric surgery in people with diabetes
This study looks at how bariatric (weight-loss) surgery affects bone health in adults with type 2 diabetes. It may help doctors understand who needs extra bone protection after surgery.
Montreal, QuebecAges 18–60 - NCT03568630Recruiting
Blood tests to study early pancreatic cancer risk
This study looks at blood “markers” to find early signs or higher risk for pancreatic cancer. You may join if you have certain risk factors (like new diabetes, pancreatic cysts/pancreatitis, or a strong family history) and can come to Omaha for blood draws twice a year.
Omaha, NebraskaAges 19 years+ - NCT03842475Recruiting
Who may benefit from weight-loss surgery for diabetes?
This study looks at which people with type 2 diabetes (or prediabetes) are most likely to benefit from bariatric surgery. It compares people who are planning surgery with healthy volunteers to better understand how body changes relate to blood sugar.
London, Greater LondonAges 18–80 - NCT04455867Recruiting
Study of type 2 diabetes risk and early treatment
This study looks at people who may be on the way to developing type 2 diabetes or who have it, to see how to help and better understand the condition. Depending on the part of the study you join, it may include brain scans and sleep testing.
Toronto, OntarioAges 18 years+ - NCT06007404Recruiting
Understanding metabolism and inflammation in teens
This study looks at how metabolism and inflammation relate to diabetes risk in teenagers. It may help researchers understand why some teens develop type 2 diabetes.
Ann Arbor, MichiganAges 14–18 - NCT04943861Recruiting
Study on HIV and food insecurity support
This study is looking at food insecurity in adults living with HIV. It may help improve understanding of the barriers to healthy living and guide better support for people affected by HIV.
Winston-Salem, North CarolinaAges 18 years+ - NCT05026723Recruiting
Food plan to improve health for HIV and type 2 diabetes
This study tests whether a personalized “food as medicine” approach can help people manage health related to HIV and type 2 diabetes or prediabetes risk. If you struggle with having enough healthy food, the program may focus on practical ways to improve diet and support healthier blood sugar.
Chapel Hill, North CarolinaAges 18 years+ - NCT05041491RecruitingEarly Phase 1
Breaking up sitting time to improve blood sugar
This study tests whether changing how often you sit (adding movement breaks) can improve blood sugar control in people at risk for type 2 diabetes. It compares two activity patterns and uses monitoring and brief hospital-style visits with controlled food.
Aurora, ColoradoAges 18–64 - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT05776420RecruitingPhase 3
Healthy food vouchers to improve blood sugar control
This trial tests whether giving people a healthy food voucher helps lower blood sugar levels in people who have prediabetes or type 2 diabetes. It also aims to support people who struggle with food or money by improving access to healthier foods.
TorontoAges 19 years+ - NCT05799222Recruiting
Nutrition program for obesity and diabetes risk
This trial tests a medically guided nutrition program to help improve weight and blood sugar in adults with obesity or early diabetes risk. It specifically targets people who meet income guidelines and don’t already use most diabetes or anti-obesity medicines.
Boston, MassachusettsAges 18–65 - NCT05844644RecruitingPhase 2
Golo plan for weight and blood sugar in prediabetes
This trial tests whether the Golo for Life plan (with a release supplement) can improve blood sugar and help with weight in adults who have prediabetes or type 2 diabetes. If you join, you’ll follow the program and attend clinic visits while your health, diet, and weight are tracked.
LaSalle, OntarioAges 18–75 - NCT06055036Recruiting
Stress reduction for heart health in Black men
This study looks at how reducing stress can improve cardiovascular health in Black men. It involves lifestyle changes and support to help lower your risk of heart disease.
Columbus, OhioAges 18 years+ - NCT06067139Recruiting
Sleep therapy to lower diabetes risk in prediabetes
This study tests if a sleep-focused therapy (cognitive behavioral therapy for insomnia, or CBT-I) can lower diabetes risk in people with prediabetes and insomnia. Participants will receive online therapy sessions and wear a monitor to track blood sugar and sleep.
Portland, OregonAges 22–79 - NCT06115876Recruiting
Kuwait diabetes long-term follow-up study
This study checks in on people with prediabetes or type 2 diabetes who were part of an earlier Kuwait diabetes study. It aims to understand how their condition has changed and what health care they may need.
Kuwait CityAges 21–75 - NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Chandler, ArizonaAges 55 years+ - NCT07167004Recruiting
Boosting nutrition with whole grains for prediabetes or diabetes
This study tests if providing whole-grain foods through online grocery shopping can improve nutrition for people with prediabetes or diabetes. It aims to help you manage your blood sugar better.
Philadelphia, PennsylvaniaAges 45–70 - NCT06384313Recruiting
Butyrate supplement for preventing diabetes
This study tests if a special type of fat (butyrate) can help prevent diabetes in people who are overweight and have early signs of blood sugar problems. You would take a supplement for several weeks to see if it improves how your body handles sugar.
Maastricht, LimburgAges 20–70
Hear when a new Prediabetes / Type 2 Diabetes trial opens
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Common questions
- Are there clinical trials for prediabetes / type 2 diabetes?
- Yes. Clin2 currently lists 75 recruiting prediabetes / type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prediabetes / type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prediabetes / type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.