Clinical trials
Preoperative clinical trials
Below are recruiting preoperative clinical trials, each written for real people, not researchers. We’re tracking 376 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07694934Recruiting
Operation Calm virtual reality study for children and teens
This study tests a virtual reality (VR) tool called Operation Calm to help children and teens feel calmer during medical, dental, or other procedures. Parents and healthcare workers also try it and share their thoughts.
MontrealAges 6 years+ - NCT05810571Recruiting
Pain-control injections compared after open kidney surgery
This study compares two types of pain-control injections placed near the back to see which works better after open kidney (nephrectomy) surgery. If you’re having elective open nephrectomy, it may help doctors choose the safest and most effective way to reduce postoperative pain.
İzmitAges 18–85 - NCT07687875RecruitingPhase 1
Virus therapy plus immunotherapy before surgery for rectal cancer
This trial tests a combination of a cancer-killing virus (oncolytic virotherapy) and an immunotherapy drug (pembrolizumab) given before surgery for a certain type of rectal cancer. It aims to see if this approach helps shrink the tumor and improve outcomes for patients whose tumors have a normal DNA repair system (pMMR).
Copenhagen, Captial RegionAges 18 years+ - NCT07677917Enrolling by invitationPhase 1
Medicine to reduce restlessness after sinus surgery
This trial tests two inhaled medicines, dexmedetomidine and magnesium sulfate, to see which is better at preventing agitation and restlessness as patients wake up from functional endoscopic sinus surgery. It may help you recover more calmly.
CairoAges 21–50 - NCT07675993Recruiting
Sleep and anesthesia in non-heart surgery
This study looks at how sleep problems before surgery affect the amount of anesthesia needed and how well you recover after non-cardiac surgery. The goal is to help doctors personalize care for better recovery.
Yinchuan, NingxiaAges 18–65 - NCT07675889Recruiting
Comparing two ways to find a small lung nodule during surgery
This study compares two ways of marking a small lung nodule before surgery to remove it. One method uses a CT scan to guide a needle into the lung before surgery, and the other method finds the nodule during the operation itself. The goal is to see which method is safer and more accurate.
Xingyi, GuizhouAges 18–80 - NCT07669987Recruiting
Heart bypass surgery and artery imaging study
This study looks at whether a special imaging test called QFR, done before heart bypass surgery, can help predict how well the radial artery graft will work shortly after surgery. If you have severe blockages in your heart arteries and are scheduled for bypass surgery, this trial may be relevant.
Beijing, Beijing MunicipalityAges 18–80 - NCT07666074Recruiting
AI for predicting difficult airway in weight-loss surgery
This trial uses artificial intelligence (AI) to predict whether it will be difficult to place a breathing tube during weight-loss surgery. The goal is to help doctors plan safer anesthesia for patients with a high BMI.
Elâzığ, ElâzığAges 18–65 - NCT07658326Recruiting
Stress and rotator cuff surgery study
This study looks at how stress before surgery might affect recovery in people having rotator cuff surgery. You may be able to join if this is your first surgery for a torn rotator cuff and you don't have certain other health problems.
CornebarrieuAges 18 years+ - NCT07656649Recruiting
Sip-til-Send: Clear liquids before surgery
This trial tests whether allowing patients to drink clear fluids (like water or juice) up until surgery starts is safe, instead of fasting for hours. It may help you feel more comfortable before your operation.
Bergen, VestlandAges 18 years+ - NCT07657845Recruiting
Long-term safety of a freezing nerve block before pectus surgery
This study checks the long-term safety of a procedure called cryoneurolysis, which uses cold to temporarily numb certain nerves before surgery to fix a sunken chest (pectus excavatum). It may be for people who already had this treatment.
Bergamo, BGAges 14 years+ - NCT07660679Recruiting
Carotid ultrasound before liver transplant surgery
This study looks at whether measuring the thickness of the carotid artery (the main artery in the neck) before a planned liver transplant can help doctors predict and manage blood flow changes during surgery. It may help patients get safer care during their transplant.
DiyarbakırAges 18 years+ - NCT04973293Recruiting
Pre-surgery immunotherapy plus chemo and blood-vessel medicine for lung cancer
This study tests whether giving sintilimab (an immune therapy) combined with bevacizumab (a blood-vessel–targeting medicine) plus chemotherapy before surgery can improve outcomes for resectable lung cancer. It’s meant for people with specific lung cancer types and good health for surgery, and it avoids certain cancer types and immune-related risks.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06697938Recruiting
Chemo plus radiation vs. chemo alone for locally advanced breast cancer
This trial compares two treatments for locally advanced breast cancer: chemotherapy before surgery plus radiation, versus chemotherapy before surgery alone. The goal is to see which approach works better for this specific type of cancer.
Chengdu, SichuanAges 18–70 - NCT07628205Enrolling by invitationPhase 2
Botulinum Toxin to Help Close Large Belly Wall Hernias
This study tests whether injecting botulinum toxin (Botox) before surgery can help close large holes in the belly wall by relaxing the muscles and making it easier to bring the edges together. This might reduce complications and improve healing after surgery.
Legnano, MilanoAges 18 years+ - NCT06699446Recruiting
Seamless care from before to after heart surgery
This study is for people who are getting ready for heart surgery and want to follow a program that helps them prepare and recover. It tests a seamless approach from before surgery through rehabilitation, focusing on exercise and support.
Hanover, Lower SaxonyAges 18 years+ - NCT07609329Recruiting
Nutritional Support Before Sarcoma Surgery
This study tests whether special nutritional supplements given before surgery for bone or soft tissue sarcoma (a type of cancer) can help your body heal better and recover faster. You'll take oral supplements for at least a week before your planned surgery.
BrnoAges Any age - NCT07608861Recruiting
Numbing Block to Reduce Pain Medicine During Nose Surgery
This study tests whether a special numbing injection in the upper jaw (bilateral maxillary block) helps reduce the amount of pain medication needed during septorhinoplasty—a surgery to reshape the nose and straighten the septum. The goal is to find ways to use less strong pain medication during surgery.
Yenimahalle, AnkaraAges 18–65 - NCT06716892Recruiting
Non-invasive imaging for head and neck tumors
This trial is testing a new, non-invasive imaging technique called MSOT to look at head and neck tumors. It compares images from people with tumors to healthy volunteers, aiming to improve how doctors evaluate tissue before surgery.
Erlangen, BavariaAges 18 years+ - NCT07589127Recruiting
Nerve Block for Pain Relief During Knee Replacement
This study tests whether blocking a specific nerve in the knee can reduce pain and improve recovery after total knee replacement surgery. You would receive this nerve block alongside standard anesthesia to see if it helps you need fewer pain medications afterward.
Hjelset, Møre og RomsdalAges 18–80 - NCT07587437Enrolling by invitation
Magnetic Camera Exam Before Weight-Loss Surgery
This study tests a swallowable magnetic camera to examine your stomach and small intestine before bariatric (weight-loss) surgery. The camera may help doctors plan your surgery and catch any issues beforehand.
Cleveland, OhioAges 18 years+ - NCT07588178Recruiting
Sleep Problems Before Heart Surgery: Study on Recovery
This research examines how sleep issues before heart surgery may affect how well patients recover afterward. Researchers will study blood markers and chemical changes to better understand this connection and potentially improve surgical outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06721286RecruitingPhase 2
Combining immunotherapy with chemotherapy before surgery for bile duct cancer
This trial tests whether adding an immunotherapy drug (toripalimab) to standard chemotherapy before surgery can improve outcomes for people with intrahepatic cholangiocarcinoma that can be surgically removed. It's for patients who haven't had prior treatment for their cancer and are in good overall health.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07581691Recruiting
Ultrasound Stomach Checks Before Surgery in Children
This study tests whether ultrasound scans of the stomach before surgery help keep children safe during anesthesia. Researchers will measure how full the stomach is to make sure children are ready for surgery.
KayseriAges birth–18 years
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Common questions
- Are there clinical trials for preoperative?
- Yes. Clin2 currently lists 376 recruiting preoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a preoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a preoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.