Clinical trials
Preoperative clinical trials
Below are recruiting preoperative clinical trials, each written for real people, not researchers. We’re tracking 374 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07368205Recruiting
Risk assessment before surgery for endometrial cancer
This trial looks at better ways to predict how aggressive your endometrial cancer is before surgery, so doctors can decide if they need to check your lymph nodes. It may help tailor your treatment to avoid unnecessary procedures.
Hradec KrálovéAges 18 years+ - NCT06623656RecruitingPhase 2
Pre-surgery treatment comparison for non-small cell lung cancer
This trial compares two treatment approaches before surgery for non-small cell lung cancer (NSCLC): radiation plus immunotherapy versus chemotherapy plus immunotherapy. The goal is to see which combination works better to shrink the tumor before it is removed.
New York, New YorkAges 18 years+ - NCT07356895Recruiting
Social stories for children with autism having surgery
This trial tests if reading a special storybook at home helps children with autism feel calmer and cooperate better when they go in for surgery.
AnkaraAges 3–18 - NCT07357571Recruiting
Can ultrasound help predict lymph node spread in early thyroid cancer?
This trial uses contrast-enhanced ultrasound before surgery to see if it can predict whether cancer has spread to lymph nodes in patients with early-stage papillary thyroid cancer. The goal is to improve treatment planning without unnecessary surgery.
Guangdong, GuangzhouAges Any age - NCT07350928RecruitingPhase 3
Nasal spray before breast-saving surgery for calm wakefulness
This trial tests a nasal spray (dexmedetomidine) given before breast-conserving surgery to help you stay calm and comfortable while awake during the procedure. It aims to improve your recovery and waking experience after surgery.
TianjinAges 20–70 - NCT07339202Recruiting
Timing of dialysis before surgery for kidney failure
This study looks at the best timing for dialysis before planned surgery in people with kidney failure. It aims to find out if changing when you have dialysis can improve recovery and reduce complications.
Stanford, CaliforniaAges 18 years+ - NCT06533397Recruiting
Testing a new bone graft for sinus lifts
This study tests a new bone graft material for sinus lifts, a procedure to add bone in the upper jaw so dental implants can be placed. It may help people who are missing bone in the back of their upper jaw due to enlarged sinuses.
Budapest, BudapestAges 18 years+ - NCT06688851Recruiting
Custom implants for jaw cysts
This study tests custom-made implants to help treat jaw cysts that are near important structures. It may be an option for people whose cysts are in tricky locations where standard surgery might be risky.
Budapest, BudapestAges 18 years+ - NCT07551375Recruiting
Fast MRI scan to diagnose gallbladder inflammation
This study tests whether a new type of quick MRI scan can reliably detect acute cholecystitis—sudden inflammation of the gallbladder. If it works well, doctors may be able to diagnose this condition faster and help patients get treatment sooner.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07324967Recruiting
Counseling for transmasculine patients before gender-affirming surgery
This study tests a counseling approach to help transmasculine and non-binary people prepare for a hysterectomy (removal of the uterus) as part of gender-affirming care. The goal is to see if this counseling improves knowledge and decision-making.
Minneapolis, MinnesotaAges 18–65 - NCT07322497Recruiting
Phone app vs. supervised exercise before ACL surgery
This study compares two ways to exercise before ACL surgery: using a video app on your phone versus doing exercises with a physical therapist. The goal is to see which approach helps you recover better.
Istanbul, KartalAges 18–45 - NCT07276880RecruitingPhase 2
Chemo, immunotherapy, and radiation for lymph node-positive triple-negative breast cancer
This trial tests a combination of chemotherapy, the immunotherapy drug pembrolizumab, and low or high-dose radiation before surgery for people with triple-negative breast cancer that has spread to the lymph nodes. The goal is to see if this approach can improve treatment outcomes.
Chapel Hill, North CarolinaAges 18 years+ - NCT05092126Recruiting
Testing a pre-surgery breathing and heart check tool
This study is developing and checking how well a pre-surgery evaluation system (using objective body measurements) can predict and help around the time of anesthesia and surgery. You might be asked to complete a clinic screening and provide consent, as long as your results fit their safety and screening thresholds.
Durham, North CarolinaAges 18 years+ - NCT06806059Recruiting
Exercise before bladder removal surgery study
This study looks at whether being active before bladder cancer surgery helps you recover with fewer problems. It tests how physical activity before surgery affects your health afterwards.
Munich, BavariaAges 18 years+ - NCT07315308Recruiting
Nerve block before heart surgery and painkiller use
This study tests whether a numbing injection in the chest before heart surgery can reduce the amount of pain medicine needed during the operation. It may help you manage pain better and recover more comfortably.
Gaziantep, SahinbeyAges 18–65 - NCT07450014Recruiting
Does anxiety before surgery affect risks from spinal anesthesia?
This study looks at whether how anxious you feel before surgery affects your risk of a sudden drop in heart rate and blood pressure (vasovagal event) when you receive spinal anesthesia. Participation may help doctors better understand and prevent these episodes.
SanliurfaAges 18–65 - NCT05428358Recruiting
MRI helps choose which pancreatic cancer patients can have surgery
This trial studies whether adding an MRI scan improves the selection of people with pancreatic cancer who may benefit from surgery. It focuses on patients without liver spread and with tumors that are borderline or likely removable.
AalborgAges 18–99 - NCT07304115Recruiting
Noise from mechanical heart valve and quality of life
This study looks at how the noise from a mechanical heart valve affects your quality of life after surgery. You will be asked about your memories of the information you received before surgery and how you feel now.
ParisAges 18 years+ - NCT07294690Recruiting
Virtual reality training before colorectal cancer surgery
This study uses virtual reality training before colorectal cancer surgery to see if it helps reduce anxiety and prepare you better for the procedure, leading to a smoother recovery.
IstanbulAges 18–70 - NCT07287605Recruiting
Virtual reality for mood during focused ultrasound for essential tremor
This study tests if using virtual reality can improve your mood while you undergo a focused ultrasound procedure for essential tremor. If you are already scheduled for this treatment, you may be able to join.
North York, OntarioAges 18 years+ - NCT05545007Recruiting
Pre-op vs post-op focused radiation for large brain metastases
This study compares giving focused, high-dose radiation before surgery versus after surgery for people with large brain metastases. The goal is to see which timing works best to control the tumors and help neurological outcomes.
Brescia, BresciaAges 18 years+ - NCT05357846RecruitingPhase 3
Check whether PD-1 treatment helps esophagus cancer before surgery
This Phase 3 trial tests whether adding a PD-1 medicine (sintilimab) to standard chemo-radiation before surgery improves outcomes for locally advanced esophageal squamous cell cancer. It may help by strengthening the immune response while shrinking the tumor before an operation.
Guangzhou, GuangdongAges 18–70 - NCT07278661RecruitingPhase 2
Pre-surgery romiplostim for patients with low platelets having heart surgery
This trial tests if giving romiplostim before heart surgery can safely increase low platelet counts. It may help patients with low platelets avoid bleeding complications during and after surgery.
AngersAges 18 years+ - NCT07270445Recruiting
VR for anxiety before surgery
This study tests whether using virtual reality (VR) before surgery can help lower anxiety. If you are an adult having planned surgery and are comfortable using a VR headset, you may be able to join.
BonnAges 18 years+
Hear when a new Preoperative trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for preoperative?
- Yes. Clin2 currently lists 374 recruiting preoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a preoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a preoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.