Clinical trials
Preterm clinical trials
Below are recruiting preterm clinical trials, each written for real people, not researchers. We’re tracking 286 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04413994Recruiting
Exclusive breast milk study in preterm babies
This study tests whether feeding extremely preterm babies only human milk (no formula) affects early health outcomes, including risks that may develop later. It also includes term-born babies for comparison. The study is mainly about feeding and safety, and you would follow the study’s feeding plan.
Innsbruck, TyrolAges 1 day–5 years - NCT04430790RecruitingPhase 3
Doxapram for apnea in very preterm babies on breathing support
This trial studies whether the medicine doxapram can better treat breathing pauses (apnea) in very preterm babies who are already on breathing support in the NICU. It aims to reduce the need for extra interventions and improve outcomes in this high-risk group.
Brussels, Avenaue Hippocrate 10Ages 5 months–7 months - NCT04644094Recruiting
Dexamethasone for heart function after very early birth
This study looks at how giving a steroid medicine (dexamethasone) after very early birth affects the baby’s heart function. It may help doctors better understand risks and benefits for babies who need treatment for serious lung problems.
Montreal, QuebecAges 1 minute+ - NCT04685356Recruiting
Testing IBAIP for brain development in very preterm babies
This study looks at whether the IBAIP program can improve neurodevelopment (how the brain grows and works) in babies born very early. Babies are included only if they have a normal early neurological exam after being “corrected for prematurity.”
AngersAges 6 months–7 months - NCT04777760Recruiting
Surfactant treatment for newborn breathing distress
This trial looks at giving a “surfactant” medicine (a substance that helps keep baby lungs open) to newborns who have serious breathing problems soon after birth. It may help babies with neonatal respiratory distress or acute breathing distress, especially if they’re treated in the early time window.
Chongqing, Chongqing MunicipalityAges 1 minute–1 day - NCT04821544Recruiting
Study of stress in new mothers and how it affects breastmilk
This study looks at how stress in new mothers may change their breastmilk and how that relates to newborn health outcomes. It is specifically recruiting mothers with babies in certain NICUs.
Coeur d'Alene, IdahoAges 18–50 - NCT04856501Recruiting
Parenting support for preterm toddlers’ brain and self-control
This study tests whether a responsive parenting program helps toddlers born early think, learn, and manage behavior more easily. It also checks whether families can complete toddler brain and behavior assessments (including brain scans).
Houston, TexasAges 1.3 years–2.5 years - NCT04911452Recruiting
Calmer NICU care for very preterm babies
This study tests a calmer approach in the NICU to help very preterm babies grow and develop their brains. It may be helpful if your baby needs breathing support and is in the early weeks of life.
Vancouver, British ColumbiaAges 6 months–7 months - NCT04939571Recruiting
Registry for babies with retinopathy of prematurity
This study is a European registry that collects medical information (stored electronically) about babies who have retinopathy of prematurity (ROP) severe enough to need treatment. It may help doctors understand outcomes and improve care by tracking real-world results.
SalzburgAges Any age - NCT05012072Recruiting
Lifestyle coaching to lower pregnancy stress and risk
This study tests a lifestyle coaching program to help reduce stress and improve emotional wellbeing during pregnancy. It may help lower risks for the baby by supporting healthier daily routines and mental health.
Webster, TexasAges 18–45 - NCT05017389Recruiting
Long-term health follow-up for premature newborns
This study follows babies born early (premature) over the long term to learn how they grow and develop. It mainly helps doctors understand long-term health needs after early birth.
Shanghai, Shanghai MunicipalityAges 2 weeks–4 months - NCT05030337Recruiting
Closed-loop oxygen control for very preterm babies on ventilators
This trial tests a computer-guided (“closed-loop”) oxygen control system for very preterm babies who need breathing support. It aims to keep oxygen levels safer and more consistent than standard care.
LondonAges Any age - NCT05063149RecruitingPhase 3
Preemie immune treatment to prevent lung infections and wheezing
This study tests whether a bacterial “lysate” medicine, given to preterm babies, can reduce respiratory (lung) infections and wheezing. It may help protect babies’ airways during the vulnerable first months after birth.
Rotterdam, South HollandAges 1 month–2 months - NCT05207852Recruiting
Dexamethasone study for preterm labor lung development
This trial studies how well dexamethasone works and how it behaves in the body when given during preterm labor to help the baby’s lungs mature. You may be able to join if you’re pregnant between 24–36 weeks and are receiving the study treatment per their schedule.
BeijingAges 20–40 - NCT05223192Recruiting
Testing music to improve breathing and brain oxygen in preemies
This study looks at whether planned music sessions can help preterm babies breathe more steadily and improve oxygen reaching the brain. It may help staff learn how to use music therapy safely for newborns in the NICU.
New York, New YorkAges 6 months–9 months - NCT05230199Recruiting
Improving the hospital environment for newborn comfort
This study tests whether changing the hospital environment can improve comfort and care for newborns who are very early in life. It focuses on babies who are delivered early and enrolled right away after birth.
St Louis, MissouriAges 1 day–1 week - NCT05231200Recruiting
Improving care for late preterm babies in NICUs
This trial uses a “quality improvement” program to improve how late preterm babies are cared for in participating hospitals’ newborn units. It may help families indirectly by improving team practices and coordination in the NICU.
Calgary, AlbertaAges 7 months–8 months - NCT05264779Recruiting
Decision help tool for very early delivery planning
This study tests a decision-support tool (a structured way to guide conversations) for parents facing a high risk of delivering very early (about 22–26 weeks). It may help you and your baby’s care team make clearer, more aligned choices about neonatal (newborn) treatment.
San Diego, CaliforniaAges 18 years+ - NCT05272579RecruitingEarly Phase 1
Phage treatment to help gut development in very preterm babies
This early-phase trial tests whether giving a specific bacteria-fighting treatment (called bacteriophage) through the gut can help preterm babies’ intestinal development mature faster. It may help reduce early gut-related problems, but the study is mainly to check safety and early effects.
CopenhagenAges Any age - NCT05285345Recruiting
A new discharge plan for very premature babies with lung disease
This trial tests a standardized, team-agreed discharge plan to help preterm babies with lung disease (often called BPD) leave the hospital safely. It may help by making the discharge process more consistent, especially for babies going home on breathing support like oxygen.
Boston, MassachusettsAges birth–1 year - NCT05298748Recruiting
Audio recordings to help breathing control mature in preterm babies
This trial studies whether listening to special “womb” sounds can help a preterm baby’s breathing control develop as they grow. It may help babies who are already breathing on their own (with low or no extra oxygen support).
Cleveland, OhioAges 1 week–1 month - NCT05306925Recruiting
Arginine supplement study for newborns after major gut surgery
This study looks at whether giving an amino-acid supplement called arginine to newborns after major bowel surgery can improve the baby’s immune response. It may help doctors understand how to support recovery after conditions like necrotizing enterocolitis or certain birth defects.
Liverpool, MerseysideAges 5 months–10 months - NCT05336890Recruiting
Using past oxygen data to predict risks after premature birth
This study builds a personalized computer model that uses earlier breathing/oxygen information from preterm infants to predict possible health or development outcomes by preschool age. It may help families and doctors better estimate risks and plan support, using information already collected in a previous study.
Chicago, IllinoisAges 7 months–6.9 years - NCT05340465RecruitingPhase 2
IV iron in preterm babies to reduce blood transfusions
This Phase 2 study tests whether giving a specific IV iron (darbe plus IV iron) can help preterm babies need fewer blood transfusions while still keeping their iron levels in a safe range. It focuses on babies in the NICU who were born early, and it compares transfusion use and iron sufficiency over time.
Seattle, WashingtonAges Up to 3 days
Hear when a new Preterm trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for preterm?
- Yes. Clin2 currently lists 286 recruiting preterm studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a preterm trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a preterm trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.