Clinical trials
Preterm clinical trials
Below are recruiting preterm clinical trials, each written for real people, not researchers. We’re tracking 286 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05347238Recruiting
Dopamine or norepinephrine for low blood pressure in very preterm babies
This trial compares two common medicines—dopamine versus norepinephrine—to treat low blood pressure in very preterm babies who have suspected or confirmed late-onset bloodstream infection (sepsis). It may help doctors find which medicine works better and more safely for this specific situation.
Phoenix, ArizonaAges 5 months–7 months - NCT05380401Recruiting
DHA and ARA milk fats for very early preterm babies
This study looks at how adding two specific milk fats (DHA and ARA) through enteral feeding affects metabolism in very early preterm infants. It may help researchers understand what these nutrients do in babies born around 25–30 weeks gestation.
Los Angeles, CaliforniaAges Up to 8 months - NCT05397197Recruiting
Studies how early birth affects learning new words
This study looks at how being born early (between 32 and 36 weeks) or at full term affects a baby’s vocabulary learning. It also compares babies who have typical newborn health checks to better understand what might influence language development.
MarseilleAges birth–2 years - NCT05537454Recruiting
Study how maternal stress and milk affect preterm baby development
This study looks at whether stress during pregnancy and differences in breast milk are linked to how preterm babies develop, especially their early brain development. If you and your baby meet the criteria, the team will collect information and samples while your baby is still in the hospital.
Minneapolis, MinnesotaAges 6 months–8 months - NCT05604846Recruiting
Probiotic drops for very preterm babies in Scandinavia
This trial studies whether giving probiotic supplements to extremely preterm newborns helps improve health outcomes. It’s meant for babies born very early, and the results could help guide safer early nutrition and care.
Solna, Stockholm CountyAges 5 months–6 months - NCT05636397Recruiting
Oral L-citrulline for fragile preterm babies with lung or bowel disease
This trial studies whether an oral medicine called L-citrulline (L-cit) is safe and how it works in very preterm infants. It includes two groups: babies with chronic lung disease (with or without high blood pressure in the lungs) and babies recovering from severe bowel infection (NEC).
Toronto, OntarioAges 1 month–6 months - NCT05651347RecruitingPhase 3
Melatonin in pregnancy to protect babies with slow growth
This trial studies whether taking melatonin during pregnancy can help protect the baby’s brain and organs in cases of poor fetal growth. It focuses on pregnancies at a specific gestational age with signs that the placenta may not be working well.
Camperdown, New South WalesAges 18 years+ - NCT05670951RecruitingPhase 3
Drug ELGN-2112 for gut absorption problems in preterm babies
This Phase 3 trial tests whether ELGN-2112 helps preterm babies absorb food from the intestines. It aims to improve intestinal malabsorption and check safety.
NetanyaAges 1 day–5 days - NCT05675397Recruiting
Donor milk supplement for very small preterm babies
This study looks at giving donor human milk to very low-birth-weight preterm babies when a mother’s own milk is not enough during the first three weeks. It may help babies get human milk instead of formula during that early period.
AthensAges 1 day–3 weeks - NCT05675969Recruiting
Testing tiny blood particles in at-risk early delivery
This pilot study looks at tiny particles in blood (microvesicles) to learn how they differ in women with threatened preterm delivery, with or without pre-eclampsia. Results may help doctors better identify risk and improve care for early delivery.
BordeauxAges 18 years+ - NCT05726578Recruiting
Ultrasound checks of lung recruitment in preterm, ventilated babies
This trial studies how ultrasound of the heart and lungs can show which airspaces in the lungs are opening up (“lung recruitment”) in preterm babies who are having breathing trouble and need an advanced breathing machine. It may help clinicians better monitor lung recovery and adjust care.
AlexandriaAges 1 hour–3 days - NCT05861531Recruiting
Oral stimulation and language support for preterm feeding
This study tests whether a feeding-focused therapy that includes mouth stimulation and language support helps preterm babies feed more effectively. It may be most helpful for babies born very early who are learning to feed safely and comfortably.
Providence, Rhode IslandAges 5 months–7 months - NCT05865977Recruiting
Test a breathing check to prevent breathing tube failure in preemies
This study checks a specific bedside breathing test (called an SBT) to see if it can better predict when a premature baby is likely to fail extubation (having the breathing tube removed). If the test is accurate, it may help doctors time tube removal more safely and reduce complications.
Chongqing, Chongqing MunicipalityAges 2 days–6 months - NCT05893485Recruiting
Music therapy for people at risk of early delivery
This study looks at how listening to music during pregnancy (and after birth) affects mood and body functions for people whose pregnancy is at high risk of early delivery. It may help see whether music therapy is a safe, comforting add-on when you’re hospitalized and worried about preterm birth.
Houston, TexasAges 18–64 - NCT05904626RecruitingPhase 2
ELGN-2112 safety study for very preterm and small babies
This Phase 2 trial studies whether ELGN-2112 is safe in babies born very early or smaller than expected before birth. It may help doctors understand how to better care for these high-risk newborns.
NetanyaAges 1 day–5 days - NCT05908227Recruiting
Testing nasal high-flow settings in stable preterm babies
This study tests how different nasal high-flow “flow strength” settings affect breathing stability in preterm infants. It may help clinicians choose settings that keep heart rate and breathing steadier.
Mainz, Rhineland-PalatinateAges 5 months–7 months - NCT05934318Recruiting
Arginine supplements to help prevent pregnancy complications
This study tests whether taking an arginine-based supplement during pregnancy can help lower the risk of bad pregnancy outcomes. You may be eligible if you are pregnant in the early-to-mid period and meet safety and location requirements.
KisumuAges 16–40 - NCT05942924Recruiting
NEU-STIM for breathing support in very premature newborns
This trial studies whether NEU-STIM can help support breathing and oxygen levels in babies born very early. If your baby is born before 32 weeks, the study may include them after you provide consent.
GrazAges Up to 7 months - NCT05960929RecruitingPhase 3
Breathing support for premature babies with lung distress
This Phase 3 trial tests whether InfasurfAero™ (a type of surfactant given as aerosol) works better than a sham treatment in preterm babies with respiratory distress syndrome (RDS). It aims to improve breathing in the first hours of life for babies who need CPAP.
Phoenix, ArizonaAges 7 months–8 months - NCT05969431Recruiting
Measuring hair cortisol to study stress in fathers of babies
This study looks at whether a father’s stress level over time can be estimated by measuring cortisol (a stress hormone) in hair. Results may help researchers better understand how chronic stress affects new families, especially when babies are born early or on time.
Cologne, Northrhine-westfaliaAges 1 day–1 week - NCT06026163RecruitingPhase 2/Phase 3
Caffeine for breathing help in late preterm babies
This trial tests if giving caffeine to late preterm babies with breathing problems helps them need less breathing support. It could be an extra treatment alongside standard care.
Madinah, Medina RegionAges 1 day–3 days - NCT06031324Recruiting
Lung ultrasound to predict recovery in newborns with breathing trouble
This study looks at whether a lung ultrasound (a safe, painless scan) can help predict how well a newborn will recover from breathing problems that start right after birth. It may help doctors decide on the best care more quickly.
BursaAges 30 minutes–2 hours - NCT06033131RecruitingPhase 3
Metformin to help prolong pregnancy in preterm preeclampsia
This trial tests whether metformin, a common diabetes medication, can help women with preeclampsia stay pregnant longer before delivery. If you have been diagnosed with preeclampsia and your doctors are monitoring you without immediate delivery, this study might be an option.
HelsinkiAges 18 years+ - NCT06063122Recruiting
Device to help preterm babies tell speech sounds apart
This study tests a new device that plays special sounds to help preterm babies learn to tell different speech sounds apart. It is for babies born between 32 and 35 weeks of pregnancy to see if the device can improve their hearing and brain development.
Atlanta, GeorgiaAges 7 months–8 months
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Common questions
- Are there clinical trials for preterm?
- Yes. Clin2 currently lists 286 recruiting preterm studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a preterm trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a preterm trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.