Clinical trials
PRF clinical trials
Below are recruiting prf clinical trials, each written for real people, not researchers. We’re tracking 70 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05858411Recruiting
Biologic gum treatments added to non-surgical cleaning
This trial studies whether adding a biologic medicine to standard non-surgical gum (periodontal) treatment can improve deep gum pockets in certain bone defects. It may help people whose gum disease has specific “intrabony” defects, but you must meet several health and medication rules.
TiranaAges 18 years+ - NCT06302296Recruiting
Speeding up braces with your own blood
This study tests whether a special injection made from your own blood (called injectable platelet-rich fibrin) can help move your teeth faster during braces treatment. It involves removing two upper premolars and then receiving the injection to see if it speeds up straightening.
HamaAges 18–26 - NCT06461312Recruiting
Two nerve blocks for pudendal neuralgia pain relief
This study tests if combining two nerve blocks—one near the pudendal nerve and one at the ganglion impar—can better relieve chronic pelvic pain from pudendal neuralgia. The goal is to find a more effective treatment for people who haven't gotten enough relief from standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06545084Recruiting
Better healing after root-end surgery using a special blood clot
This study tests whether adding a concentrated blood clot (L-PRF) to standard root-end surgery helps tooth-related infections heal faster and better. You may be a good fit if you have a persistent infection at the tip of a tooth root and need this type of surgery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06694168Recruiting
Gum surgery to repair bone loss, with or without your own healing proteins
This trial tests a gum surgery technique that preserves more of your gum tissue, with or without a special protein-rich material made from your own blood (L-PRF), to repair bone loss from gum disease.
Santiago, San BernardoAges 18 years+ - NCT06787677Recruiting
SPG pulsed radiofrequency for chronic cluster headache
This trial tests a treatment called sphenopalatine ganglion (SPG) pulsed radiofrequency for people with chronic cluster headache. It uses short bursts of energy to calm a nerve cluster in the face that is linked to the pain, and may help when standard medicines like verapamil or lithium haven't worked.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06810726RecruitingPhase 2
Platelet-rich fibrin gel for diabetic foot ulcers
This trial tests a special gel made from your own blood (platelet-rich fibrin, or PRF) to help heal diabetic foot ulcers that are not getting better with standard care. It may be an option if you have a mild-to-moderate ulcer on the bottom of your foot with good blood flow and no infection.
Corpus Christi, TexasAges 18–80 - NCT06890897Recruiting
Esketamine with pulsed radiofrequency for shingles-related face pain
This trial tests whether adding esketamine (a medicine related to ketamine) to a standard nerve treatment (pulsed radiofrequency) can better relieve face pain caused by shingles. It may help if you have ongoing, moderate-to-severe pain in your face or scalp.
BeijingAges 18 years+ - NCT07146776Recruiting
Injectable PRF and bone graft for gum disease bone defects
This trial tests a treatment for deep gum disease pockets using a combination of your own blood components (injectable platelet-rich fibrin) and a bone graft material. It aims to help regenerate bone lost to periodontitis.
Istanbul, ÜsküdarAges 18–65 - NCT07292870Recruiting
Biological treatments for deep gum bone defects
This trial tests whether biological agents can help heal deep gum bone defects that remain after standard non-surgical cleaning. It may be an option for people who still have deep pockets around their teeth and need a minimally invasive surgical procedure.
Leuven, Vlaams BrabantAges 18 years+ - NCT07293962RecruitingPhase 2
Liquid S-PRF for gum disease treatment
This study tests whether a special liquid made from your own blood (called liquid S-PRF) can improve gum health during deep cleaning for people with advanced gum disease. It lasts 3 months and may help reduce inflammation and promote healing without surgery.
Jenjarum, SelangorAges 18–65 - NCT07360093Recruiting
Nerve block for chronic hip pain from osteoarthritis
This study tests a nerve block treatment for people with long-term hip pain from osteoarthritis who haven't gotten enough relief from other treatments. It aims to see if this procedure can help reduce pain.
AnkaraAges 18–80 - NCT07383558Recruiting
Adding nerve treatment for chronic heel pain
This trial tests if adding a nerve treatment (pulsed radiofrequency of the sural nerve) to standard care helps people with long-lasting heel pain. It may reduce pain and improve function.
AnkaraAges 18–65 - NCT07393997Recruiting
Tooth transplant with platelet-rich fibrin for young patients
This trial tests a tooth transplant method that uses a healthy tooth from elsewhere in your mouth to replace a missing tooth. A special protein-rich material (platelet-rich fibrin) is placed around the new tooth to help it heal and grow roots. It's designed for children, teens, and young adults who cannot get dental implants.
BariAges 10–80 - NCT07448571Recruiting
Testing i-PRF for better root canal retreatment healing
This study tests whether using a special platelet-rich concentrate (i-PRF) during a root canal retreatment can help heal infection at the tip of the root better than standard retreatment alone. It is for adults with a previously treated upper front tooth that now shows signs of infection on X-ray.
IstanbulAges 18–50 - NCT07508033RecruitingPhase 1/Phase 2
Stem cell exosomes vs platelet-rich fibrin for socket healing
This trial tests whether stem cell exosomes (tiny healing particles from stem cells) work better than platelet-rich fibrin (a blood-derived clot) to help a tooth socket heal after extraction. It may help if you need a single front or premolar tooth removed and are generally healthy.
Tanta, Gharbia GovernorateAges 20–45 - NCT07511751Recruiting
Comparing treatments for myofascial pain syndrome
This trial compares three different treatments to find which works best for long-term back pain caused by myofascial pain syndrome, a condition where tight muscle knots cause pain. It is for people who have not found relief with standard treatments.
Adapazarı, SakaryaAges 18–65 - NCT07658170Recruiting
Fat graft with platelet-rich fibrin for breast reconstruction after lumpectomy
This trial tests using a patient's own fat plus a special blood product (platelet-rich fibrin) to rebuild the breast right after a lumpectomy for breast cancer. It may help improve healing and appearance for women with early-stage, hormone-sensitive breast cancer.
Saint PetersburgAges 18–69 - NCT07351981Enrolling by invitation
Cooled radiofrequency for knee osteoarthritis pain
This study tests a new approach called cooled radiofrequency (TcPRF) to calm knee pain from osteoarthritis. It may be an option if standard treatments haven't worked and you haven't had certain other treatments recently.
AthensAges 45 years+ - NCT07316582Enrolling by invitationPhase 4
Melatonin gel for gum disease treatment
This trial tests a new gel made with melatonin and platelet-rich fibrin to treat gum disease. It may help reduce pocket depth and improve gum health without surgery.
New CairoAges 20–60 - NCT07045545Enrolling by invitation
Comparing two layers in hypospadias repair for young boys
This trial tests two ways to add an extra layer during hypospadias repair surgery in young boys. One method uses a material made from your child's own blood (platelet-rich fibrin), and the other uses a small flap of tissue from the penis. The goal is to see which method helps the healing better.
Tashkent, CityAges Any age - NCT05591326Enrolling by invitation
Injectable platelet-rich fibrin to close gum recession
This trial tests whether an injectable healing material called platelet-rich fibrin can help cover exposed tooth root in front teeth with gum recession. If it works, it may reduce tooth sensitivity and improve appearance for people with suitable, healthy teeth and gums.
KütahyaAges 18–65
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Common questions
- Are there clinical trials for prf?
- Yes. Clin2 currently lists 70 recruiting prf studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prf trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prf trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.