Clinical trials
Probiotic clinical trials
Below are recruiting probiotic clinical trials, each written for real people, not researchers. We’re tracking 223 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06710574RecruitingPhase 4
Probiotics for sleep problems in Parkinson's disease
This study tests whether taking probiotics can improve REM sleep behavior disorder (RBD) in people with Parkinson's disease. You will receive either a probiotic supplement or a placebo, and researchers will use brain scans to see how it affects your symptoms.
BeijingAges 40–85 - NCT06728098Recruiting
Testing safety of a gut-health probiotic in healthy adults
This trial is testing a new probiotic called Akkermansia muciniphila in healthy adults. It aims to see if the supplement is safe and well-tolerated, possibly helping with gut health.
Jakarta Pusat, Jakarta Special Capital RegionAges 18–60 - NCT06746220Recruiting
Effect of activity and probiotics on body and health in women
This study looks at how adding physical activity and/or probiotics might affect your body composition and health. It is for women who are students at the University of Orléans and do not already exercise regularly.
OrléansAges 18 years+ - NCT06751979Recruiting
Probiotics for people with braces
This trial tests if a probiotic can improve oral health for people with braces. It might help reduce plaque buildup around brackets and wires.
AarhusAges 10 years+ - NCT06768931RecruitingPhase 2
Combination therapy before surgery for triple-negative breast cancer
This trial tests adding an immunotherapy drug to standard chemotherapy before surgery for triple-negative breast cancer. The goal is to see if this combination works better than chemotherapy alone.
Lanzhou, GansuAges 18 years+ - NCT06863194RecruitingPhase 1/Phase 2
Probiotics and kidney disease progression trial
This trial tests whether taking a probiotic supplement can slow down the decline of kidney function in people with moderate chronic kidney disease (CKD stages 3 and 4). If you have stable kidney disease and are not already taking probiotics, joining this study could help researchers find a new way to protect your kidneys.
Al Mansurah, DakahliyaAges 18 years+ - NCT06870331Recruiting
Probiotics for stomach health after spinal cord injury
This study tests if taking probiotics and prebiotics can help with digestion, gas, constipation, and other stomach issues in people with long-term spinal cord injury.
Nottwil, Canton of LucerneAges 18 years+ - NCT06892093Recruiting
Probiotics to prevent diarrhea from neratinib in breast cancer
This trial tests whether taking probiotics can help prevent diarrhea caused by the breast cancer drug neratinib. If you are a woman with HER2-positive breast cancer and are about to start neratinib, this study may help manage a common side effect.
Guangzhou, GuangdongAges 18 years+ - NCT06929364Recruiting
Probiotics for endometriosis – a crossover trial
This study tests whether taking a probiotic supplement can help with endometriosis symptoms. It's for women 35 or younger with moderate to severe endometriosis, and involves a crossover design where everyone gets both the probiotic and a placebo at different times.
ZagrebAges Up to 35 years - NCT06938464Recruiting
Probiotics to prevent gestational diabetes in high-risk women
This study tests whether taking probiotics (friendly bacteria) during early pregnancy can help prevent gestational diabetes in women who are at higher risk for it.
Hangzhou, ZhejiangAges 18–50 - NCT06987279Recruiting
Probiotics for hormone balance in overweight women
This trial tests whether a specific probiotic, Lactobacillus plantarum, can help regulate hormones in overweight women. It involves taking daily probiotic capsules and providing samples over a period of time.
Zhengzhou, HenanAges 18–40 - NCT07029360Recruiting
Coenzyme Q10 and Probiotics for Gum Health in Pregnancy
This trial tests whether adding coenzyme Q10 and probiotics to standard gum treatment can improve gum health and reduce inflammation in pregnant women. If you are in your second or third trimester and have gum concerns, this treatment may help both you and your baby.
Pavia, LombardyAges 18 years+ - NCT07054216Recruiting
Probiotic study for healthy newborns
This study tests whether giving a probiotic to infants can help their health. It involves pregnant people who plan to breastfeed and give birth at a specific hospital.
Hvidovre, Region SjællandAges birth–1 day - NCT07069166Recruiting
Good bacteria mouth rinse for gum disease and diabetes
This study tests whether a mouth rinse containing helpful bacteria (called parabiotics) can improve gum health in people who have both gum disease and type 2 diabetes. It may offer a simple, non-drug way to manage inflammation.
Pavia, LombardyAges 18–70 - NCT07073781Recruiting
Probiotics for Brain & Blood Sugar in Overweight Young Adults
This study tests whether taking a probiotic (a 'good bacteria' supplement) can help brain function (thinking, memory) and improve blood sugar control in overweight adults who have higher-than-normal blood sugar. If you're between 18-40, overweight, and don't have diabetes, you may be able to join.
Leeds, Greater ManchesterAges 18–40 - NCT07094035Recruiting
Green tea and probiotics for constipation-predominant IBS
This study tests whether a supplement containing green tea extract and probiotics can improve bowel function in people with irritable bowel syndrome (IBS) that mainly causes constipation. If you have chronic constipation and abdominal pain, this could help.
NaplesAges 18–70 - NCT07115342Recruiting
Probiotics and vitamin D for hay fever relief
This study tests whether taking a combination of probiotics (good bacteria) and vitamin D can help reduce hay fever symptoms. It may be a good option if your vitamin D is low and you haven't used probiotics recently.
Tanta, Gharbia GovernorateAges 18–65 - NCT07144826RecruitingEarly Phase 1
Probiotic for Gut and Vaginal Health in Ovarian Cancer Chemotherapy
This trial tests whether taking a probiotic supplement can help balance the bacteria in your gut and vagina while you undergo chemotherapy for advanced ovarian cancer. It aims to see if this could improve your treatment experience or outcomes.
Columbus, OhioAges 18 years+ - NCT07149519Recruiting
Diet and probiotics for endometriosis and IBS
This study tests whether dietary guidance and probiotics can help women with endometriosis and irritable bowel syndrome (IBS). It aims to see if these treatments improve symptoms and quality of life.
Catanduva, São PauloAges 15–50 - NCT07157462Recruiting
Testing a multi-strain probiotic for year-round allergies
This trial tests if a special probiotic blend can help people with year-round allergic rhinitis (nasal allergies) caused by common indoor allergens like dust mites, cat, or dog dander. Volunteers will take the probiotic daily and track their symptoms.
Strasbourg, AlyatecAges 18 years+ - NCT07163819RecruitingPhase 2
Probiotics for digestive health during short trips abroad
This study tests whether taking a probiotic can help prevent or reduce digestive issues when traveling abroad for less than a week. It aims to see if probiotics support overall health during short overseas trips.
Haidian, Beijing MunicipalityAges 18–65 - NCT07169019RecruitingEarly Phase 1
Probiotics and methotrexate for early psoriasis
This pilot study tests whether adding probiotics to standard methotrexate treatment improves symptoms in people newly diagnosed with chronic plaque psoriasis. It aims to see how the gut microbiome affects treatment response.
AlexandriaAges 18 years+ - NCT07182500RecruitingPhase 2
Can probiotics protect your gut while traveling?
This trial tests whether taking a probiotic supplement can help keep your gut bacteria healthy during a short trip abroad. It's a good fit if you are generally healthy and planning a vacation or business trip under a week.
Huangpu, Shanghai MunicipalityAges 18–65 - NCT07193927RecruitingPhase 2
Testing a probiotic mix for fatty liver disease (MASLD)
This trial tests whether a probiotic mixture can improve liver health in people with moderate fatty liver disease (MASLD). It looks at how the probiotic affects liver fat, inflammation, and metabolism.
Girona, GironaAges 18–75
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Common questions
- Are there clinical trials for probiotic?
- Yes. Clin2 currently lists 223 recruiting probiotic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a probiotic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a probiotic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.