Clinical trials
Probiotic clinical trials
Below are recruiting probiotic clinical trials, each written for real people, not researchers. We’re tracking 215 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07169019RecruitingEarly Phase 1
Probiotics and methotrexate for early psoriasis
This pilot study tests whether adding probiotics to standard methotrexate treatment improves symptoms in people newly diagnosed with chronic plaque psoriasis. It aims to see how the gut microbiome affects treatment response.
AlexandriaAges 18 years+ - NCT07164781Enrolling by invitation
Probiotics for preventing infections in ICU patients
This trial tests whether probiotics (good bacteria) can help prevent serious infections in critically ill patients in the ICU. If you are very sick and in the ICU, you may be able to join — as long as you don't have certain conditions like cancer or a weakened immune system.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT07163819RecruitingPhase 2
Probiotics for digestive health during short trips abroad
This study tests whether taking a probiotic can help prevent or reduce digestive issues when traveling abroad for less than a week. It aims to see if probiotics support overall health during short overseas trips.
Haidian, Beijing MunicipalityAges 18–65 - NCT07149519Recruiting
Diet and probiotics for endometriosis and IBS
This study tests whether dietary guidance and probiotics can help women with endometriosis and irritable bowel syndrome (IBS). It aims to see if these treatments improve symptoms and quality of life.
Catanduva, São PauloAges 15–50 - NCT07144826RecruitingEarly Phase 1
Probiotic for Gut and Vaginal Health in Ovarian Cancer Chemotherapy
This trial tests whether taking a probiotic supplement can help balance the bacteria in your gut and vagina while you undergo chemotherapy for advanced ovarian cancer. It aims to see if this could improve your treatment experience or outcomes.
Columbus, OhioAges 18 years+ - NCT07135362Recruiting
Probiotic for improving constipation in adults
This trial tests a probiotic supplement to see if it helps improve bowel function in people with constipation. If you have functional constipation (not caused by another illness), this study may be a good fit.
TaipeiAges 18–65 - NCT07125625Recruiting
Probiotic mixture for children with irritable bowel syndrome
This study tests whether a mixture of two friendly bacteria (probiotics) can improve belly pain and other IBS symptoms in children. If your child qualifies, they may receive the probiotic mixture or a placebo for a period of time.
Bari, BariAges 4–18 - NCT07114133Enrolling by invitation
Environmental probiotics for cat hair allergies
This study tests whether a special probiotic spray, used in your home, can reduce allergy symptoms in people who are allergic to cats. If you have cat allergies with nasal symptoms and live in a stable home, you may be able to join.
Hangzhou, ZhejiangAges 18–70 - NCT07115342Recruiting
Probiotics and vitamin D for hay fever relief
This study tests whether taking a combination of probiotics (good bacteria) and vitamin D can help reduce hay fever symptoms. It may be a good option if your vitamin D is low and you haven't used probiotics recently.
Tanta, Gharbia GovernorateAges 18–65 - NCT07102836RecruitingPhase 2
Zinc vs probiotics for jaundice in newborns on light therapy
This trial tests whether zinc or probiotics can help babies with jaundice recover faster while receiving phototherapy (light treatment). It aims to find a safe, easy way to lower bilirubin levels.
Bahawalpur, Punjab ProvinceAges birth–4 weeks - NCT07094035Recruiting
Green tea and probiotics for constipation-predominant IBS
This study tests whether a supplement containing green tea extract and probiotics can improve bowel function in people with irritable bowel syndrome (IBS) that mainly causes constipation. If you have chronic constipation and abdominal pain, this could help.
NaplesAges 18–70 - NCT06863194RecruitingPhase 1/Phase 2
Probiotics and kidney disease progression trial
This trial tests whether taking a probiotic supplement can slow down the decline of kidney function in people with moderate chronic kidney disease (CKD stages 3 and 4). If you have stable kidney disease and are not already taking probiotics, joining this study could help researchers find a new way to protect your kidneys.
Al Mansurah, DakahliyaAges 18 years+ - NCT07073781Recruiting
Probiotics for Brain & Blood Sugar in Overweight Young Adults
This study tests whether taking a probiotic (a 'good bacteria' supplement) can help brain function (thinking, memory) and improve blood sugar control in overweight adults who have higher-than-normal blood sugar. If you're between 18-40, overweight, and don't have diabetes, you may be able to join.
Leeds, Greater ManchesterAges 18–40 - NCT06987279Recruiting
Probiotics for hormone balance in overweight women
This trial tests whether a specific probiotic, Lactobacillus plantarum, can help regulate hormones in overweight women. It involves taking daily probiotic capsules and providing samples over a period of time.
Zhengzhou, HenanAges 18–40 - NCT07054216Recruiting
Probiotic study for healthy newborns
This study tests whether giving a probiotic to infants can help their health. It involves pregnant people who plan to breastfeed and give birth at a specific hospital.
Hvidovre, Region SjællandAges birth–1 day - NCT07029360Recruiting
Coenzyme Q10 and Probiotics for Gum Health in Pregnancy
This trial tests whether adding coenzyme Q10 and probiotics to standard gum treatment can improve gum health and reduce inflammation in pregnant women. If you are in your second or third trimester and have gum concerns, this treatment may help both you and your baby.
Pavia, LombardyAges 18 years+ - NCT06969872Recruiting
Probiotics for Constipation Relief
This trial tests whether taking probiotics can help relieve constipation in adults. If you have chronic constipation but no serious health issues, you may be able to join.
Taichung, SouthAges 18–75 - NCT04771728RecruitingPhase 4
Probiotics added to treatment for bacterial vaginosis
This study tests whether adding probiotics to standard care helps treat bacterial vaginosis (BV) and possibly lowers the chance of it coming back. You would be placed into a study group to compare probiotic treatment with the other approach.
Shenzhen, GuangdongAges 18–55 - NCT06949800RecruitingPhase 2
Probiotics to treat anal precancer (PROTECT trial)
This study tests if a probiotic called EXE-346 can help clear anal high-grade squamous intraepithelial lesions (HSIL), a precancerous condition, in people with HIV who are on effective antiretroviral therapy. If you have anal HSIL that wasn't fully removed by biopsy, you may be able to join.
San Francisco, CaliforniaAges 21 years+ - NCT06943235RecruitingPhase 2
Probiotics, radiation, chemo, and immunotherapy for limited-stage small cell lung cancer
This trial tests if adding probiotics (good bacteria) to standard chemoradiation and an immunotherapy drug (adebrelimab) can help treat limited-stage small cell lung cancer. It may improve how well the treatment works and reduce side effects.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06919913Recruiting
Probiotics for joint infection surgery
This study tests if taking probiotics before and after surgery can help your immune system fight infection in a hip or knee replacement. You would be given a probiotic or a placebo alongside your standard treatment.
New York, New YorkAges 18–90 - NCT06892093Recruiting
Probiotics to prevent diarrhea from neratinib in breast cancer
This trial tests whether taking probiotics can help prevent diarrhea caused by the breast cancer drug neratinib. If you are a woman with HER2-positive breast cancer and are about to start neratinib, this study may help manage a common side effect.
Guangzhou, GuangdongAges 18 years+ - NCT06870331Recruiting
Probiotics for stomach health after spinal cord injury
This study tests if taking probiotics and prebiotics can help with digestion, gas, constipation, and other stomach issues in people with long-term spinal cord injury.
Nottwil, Canton of LucerneAges 18 years+ - NCT06836960Enrolling by invitationPhase 1/Phase 2
Gegen Qinlian Tang and Probiotics for radiation gut issues
This study tests if a traditional Chinese medicine formula (Gegen Qinlian Tang) plus probiotics can help people who have gut problems from radiation treatment for cancer. It may reduce diarrhea, pain, or other bowel symptoms caused by radiation.
Jiujiang, JiangxiAges 18–80
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Common questions
- Are there clinical trials for probiotic?
- Yes. Clin2 currently lists 215 recruiting probiotic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a probiotic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a probiotic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.