Clinical trials
Progression clinical trials
Below are recruiting progression clinical trials, each written for real people, not researchers. We’re tracking 720 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00537004Recruiting
Study of language in primary progressive aphasia
This study looks at how language changes in people with primary progressive aphasia. It may help researchers better understand the condition and how it affects speech and communication over time.
Chicago, IllinoisAges Any age - NCT01730131Recruiting
Study of PML in patients, at-risk people, and healthy volunteers
This study follows people with suspected or confirmed progressive multifocal leukoencephalopathy (PML), people at higher risk, and healthy volunteers. It uses visits, brain imaging (MRI), and stored biological samples to better understand how PML progresses and who is at risk.
Bethesda, MarylandAges 2–120 - NCT02605785Recruiting
Imaging study to track tau protein in PSP
This study uses brain imaging to look at a protein called tau in people with progressive supranuclear palsy (PSP). It aims to better understand the disease and how tau changes over time, which may help future treatments.
Rochester, MinnesotaAges 35 years+ - NCT02964637Recruiting
Tests to help diagnose frontotemporal dementia
This study looks at testing (including brain scans) to figure out what type of frontotemporal dementia or related language/speech condition a person has. It may help by making diagnoses more accurate, which can guide better care.
Toronto, OntarioAges 18–90 - NCT05851209Recruiting
Study biomarkers in people with moderate aortic valve narrowing
This study looks at blood and/or body signals (called biomarkers) to understand why aortic valve narrowing may worsen and what outcomes people have. You may be able to help researchers by undergoing regular heart care plus additional testing like MRI or CT if you qualify.
BonnAges 18 years+ - NCT07647276Recruiting
Massage and relaxation for period pain relief
This study tests whether connective tissue massage (a hands-on technique) and progressive relaxation exercises can reduce severe menstrual cramps. If you have primary dysmenorrhea—painful periods without an underlying medical cause—this trial may help you find natural pain relief.
DenizliAges 18–30 - NCT07426991Recruiting
Multiple sclerosis, thinking, sleep, and tiredness study
This study looks at how multiple sclerosis (MS) affects your thinking, sleep, and tiredness. It compares people with MS who have at least mild fatigue to people without MS who also have sleep problems, to understand these issues better.
DüsseldorfAges 18–79 - NCT07576218Recruiting
Pilates and prone plank exercises for postpartum abdominal separation
This study tests whether Pilates and specific core exercises can help close the gap between abdominal muscles (called diastasis recti) that commonly happens after pregnancy. Diastasis recti can cause weakness and discomfort, and this trial evaluates whether these exercises improve that condition.
Lahore, Punjab ProvinceAges 18–45 - NCT07589621Recruiting
Managing Appearance Worries Through Behavioral Therapy
This study tests two approaches to help people who struggle with anxiety about their appearance: one focuses on gradually reducing safety behaviors (like mirror checking), while the other teaches muscle relaxation techniques. You'll use your smartphone to complete the program.
Tallahassee, FloridaAges 18–65 - NCT07653841Recruiting
Balance vs. strength training for knee osteoarthritis
This study compares two types of exercise programs (a balance-focused training and a progressive strengthening program) added to usual physical therapy. The goal is to see which works better for reducing knee pain and improving daily function in people with knee osteoarthritis.
Islamabad, ICTAges 40–70 - NCT07630623Enrolling by invitation
Relaxation and grip exercises for pregnant women with preeclampsia
This study tests whether two simple exercises—progressive muscle relaxation (tensing and releasing muscle groups) and finger grip exercises—can help pregnant women with preeclampsia manage stress, anxiety, fatigue, and sleep problems. Preeclampsia is high blood pressure during pregnancy that needs careful monitoring.
Ordu, AltinorduAges 18 years+ - NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT06960408Enrolling by invitation
Sleep, relaxation, and diabetes: A study on reducing anxiety
This study tests whether learning about good sleep habits and practicing a simple relaxation technique can help people with diabetes sleep better, feel less anxious, and improve blood sugar control.
AnkaraAges 18–64 - NCT06921265Enrolling by invitation
Magnetic brain stimulation for language in primary progressive aphasia
This study tests whether targeted magnetic stimulation to the brain can help improve language and speech in people with primary progressive aphasia. It compares the effects of real stimulation versus a placebo to see if it is a safe and useful treatment.
Milan, MilanoAges 40–85 - NCT06656130Enrolling by invitation
Breathing and relaxation for pre-hypertension
This trial tests two gentle techniques—deep breathing (Pranayama) and progressive muscle relaxation—to see if they can help lower blood pressure in people with pre-hypertension. You would attend practice sessions and follow-up visits.
Sialkot, Punjab ProvinceAges 30–60 - NCT06261528Enrolling by invitationPhase 1
Light therapy for sleepiness in progressive MS
This trial tests whether a special light therapy can help people with progressive multiple sclerosis who feel sleepy during the day. It aims to improve energy, mood, and sleep patterns.
Dallas, TexasAges 18 years+ - NCT05901233Enrolling by invitation
Remote brain stimulation and speech therapy for primary progressive aphasia
This study tests whether combining speech-language treatment with remotely supervised brain stimulation (a mild current to the scalp) can improve communication in people with primary progressive aphasia. You and a study partner would also join online training and regular video check-ins.
San Francisco, CaliforniaAges Any age - NCT07714018Recruiting
Comparing two weight loss programs for kidney cancer patients
This study tests two different weight loss programs to see which one helps prevent kidney cancer from growing in people with small kidney masses who are under active surveillance. It may help by improving overall health and potentially slowing cancer progression.
Buffalo, New YorkAges 18 years+ - NCT07775235Recruiting
Treatment outcomes for muscle inflammation with rapid lung disease
This study looks at how well treatments work for people with muscle inflammation (myositis) that causes a fast-progressing lung condition. It may help doctors find better ways to manage this serious combination.
SingaporeAges 21 years+ - NCT07779005Recruiting
Lung cancer risk factors study
This study is looking at people who have been newly diagnosed with lung cancer to learn more about what causes it and how it progresses. By participating, you can help researchers find better ways to prevent and treat this disease.
Shenyang, LiaoningAges 18–75 - NCT06382948RecruitingPhase 3
Elacestrant and everolimus for ESR1-mutant advanced breast cancer
This trial tests a new combination of two oral targeted therapy pills (elacestrant and everolimus) for people with a specific type of advanced breast cancer. It is for those whose cancer has an ESR1 mutation and has stopped responding to CDK4/6 inhibitors and hormone therapy.
InnsbruckAges 18 years+ - NCT06093906Recruiting
Positive processes and transition to health (PATH) study
This study tests a new therapy that may help people recover after a stressful life event. Over about 6 weeks, you'll work with a coach to retrain your brain's patterns and feel more in control again, as well as reconnect with positive activities.
Newark, DelawareAges 18–65 - NCT07606872Enrolling by invitation
Testing a diabetes score to guide treatment reversal
This study tests a new scoring system to help people with type 2 diabetes understand their condition better and potentially reverse or improve it. You'll use a digital platform to track blood sugar, answer health questions, and have blood tests to see if the system helps guide your treatment plan.
Manchester, EnglandAges 18 years+ - NCT07538843Recruiting
Darolutamide Plus Hormone Therapy for Prostate Cancer in China
This study watches how well a drug called darolutamide works when combined with hormone therapy for men with prostate cancer that has returned after previous treatment. The goal is to understand if this combination helps prevent cancer spread and is safe to use.
Multiple LocationsAges 18 years+
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Common questions
- Are there clinical trials for progression?
- Yes. Clin2 currently lists 720 recruiting progression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a progression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a progression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.