Clinical trials
Progression clinical trials
Below are recruiting progression clinical trials, each written for real people, not researchers. We’re tracking 716 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02329093Recruiting
Hip osteoarthritis with pain, testing non-weight bearing
This study looks at whether reducing weight on the hip can help slow how hip arthritis shows up on X-rays in people who have hip joint pain. It may be an option if your pain is from hip arthritis rather than a clear fracture.
Matsumoto, NaganoAges Any age - NCT04933669RecruitingPhase 2
Pre-surgery imatinib for high-risk stomach or gut GIST
This trial studies whether taking imatinib before surgery can shrink or control high-risk gastrointestinal stromal tumors (GIST). If you qualify, you would receive imatinib as “neoadjuvant” (before the operation) and then move on to planned surgery.
Hangzhou, ZhejiangAges 18–80 - NCT05195450Recruiting
Tenofovir to stop liver disease in mild hepatitis B
This trial tests tenofovir alafenamide (a hepatitis B antiviral medicine) to see if it can prevent liver disease from getting worse in people with chronic hepatitis B who currently have stable (normal) liver blood tests and low virus levels. It may help lower the chance of developing serious liver complications over time.
New Delhi, National Capital Territory of DelhiAges 18–70 - NCT05272371RecruitingPhase 1
Dinutuximab beta plus chemo for childhood neuroblastoma after relapse
This Phase 1 trial tests a combination of dinutuximab beta (an immunotherapy) and chemotherapy in children with high-risk neuroblastoma that did not respond to standard treatment or has come back or progressed. It aims to see how well the treatment works and how safely it can be given in this situation.
Krakow, MalopolskaAges 1–18 - NCT02194816Recruiting
Online survey study for people with Parkinson’s or Parkinsonism
This study looks at how changing certain factors over time relates to symptoms in Parkinson’s disease and related conditions. You may help researchers by completing longer online surveys every 6 months for 5 years.
Kenmore, WashingtonAges 19 years+ - NCT03789253Recruiting
Tracking genetic changes as low-risk prostate cancer becomes riskier
This study looks for genes and biological pathways that may explain why some men’s prostate cancer grows from low risk to higher risk. You may be followed using planned prostate biopsies after an initial low-risk diagnosis managed with active surveillance.
TaipeiAges 40–100 - NCT05563623Recruiting
Study of people at risk for angle-closure progression
This study follows people who have eye anatomy that suggests a higher risk of angle closure, but who do not currently have high eye pressure or glaucoma damage. It aims to understand how often and how fast this risk can progress, which may help guide earlier monitoring or prevention.
Beijing, BeeijingAges 40–75 - NCT05756959Recruiting
Tested light-based treatment plus special lenses for childhood myopia
This study tests whether combining PBM (a light/laser treatment used in eye studies) with a special myopia-defocus lens can slow nearsightedness in children. It may help reduce how fast eyesight gets worse over time.
Xuzhou, JiangsuAges 6–13 - NCT00574327Recruiting
Barrett’s and reflux registry at the Kansas City VA
This study follows people with confirmed Barrett’s esophagus (with or without concerning cell changes) and people who have reflux symptoms, to better understand how these conditions progress. It may help by building a Barrett’s registry so doctors can learn which factors predict worsening over time.
Kansas City, MissouriAges 18 years+ - NCT05255471RecruitingPhase 3
Olaparib after surgery for recurrent ovarian cancer
This trial tests whether olaparib (a pill cancer medicine) works better than standard platinum chemotherapy after a second surgery for recurrent ovarian cancer. It’s for people whose cancer returned after initial PARP-inhibitor (PARPi) maintenance and aims to see if treatment can control the cancer for longer with acceptable side effects.
NaplesAges 18 years+ - NCT05588583Recruiting
Tracking drainage from chronic leg or foot ulcers with a dressing
This study follows how much fluid (drainage) a chronic ulcer produces over time using a dressing called Mepilex Up. It may help clinicians better understand how this dressing manages “exuding” ulcers on the leg or foot.
Castro Valley, CaliforniaAges 18 years+ - NCT05663242RecruitingPhase 4
Comparing anesthetics for outcomes after lung tumor surgery
This study looks at whether using different anesthesia drugs during planned lung tumor surgery affects recovery and longer-term outcomes. It also aims to understand why the anesthesia choice might make a difference.
Kaohsiung CityAges 20–80 - NCT06024577Recruiting
Comparing exercise programs for healthy, inactive adults
This study compares different exercise programs to see which one people stick with best. It is for young and middle-aged adults who do not currently exercise regularly and are generally healthy.
San Luis Obispo, CaliforniaAges 18–40 - NCT03187925Recruiting
Treatment studies for Zenker’s or CP bar throat pouches
This trial studies people with Zenker’s diverticulum (or a related condition called CP bar) in the throat and upper food pipe. It looks at outcomes when the “shared wall” is divided using an open or endoscopic approach, or when surgery isn’t possible but follow-up can happen.
Cincinnati, OhioAges 18–100 - NCT06088225Recruiting
Myopia prevention with screen distance study
This trial tests if a distance-image screen can help prevent myopia (nearsightedness) from getting worse. It is for children ages 6 to 12 who have had recent changes in their vision.
Beijing, Beijing MunicipalityAges 6–12 - NCT03663790Recruiting
Gait retraining for knee osteoarthritis movement patterns
This trial tests whether a structured walking retraining program can improve how your leg moves if you have knee osteoarthritis. It may help reduce strain on your lower body during walking by changing walking technique.
Manassas, VirginiaAges 18–80 - NCT05895409Recruiting
Study risk factors in progressive lung scarring
This study looks at what factors contribute to worsening lung scarring seen on scans in people with certain lung diseases. Results may help doctors better understand and predict who will worsen over time.
Jinan, ShandongAges 18–80 - NCT06170177Recruiting
Life after bladder removal surgery study
This study looks at how people feel and their health after having their bladder removed. It aims to understand quality of life after this surgery.
Milan, MIAges 18 years+ - NCT05246345Recruiting
Study for chronic lymphocytic leukemia after venetoclax failure
This study looks at why chronic lymphocytic leukemia may stop responding after a medicine called venetoclax. By analyzing tumor samples, researchers hope to better understand resistance and guide future treatment options.
AmiensAges 18 years+ - NCT06123494RecruitingPhase 3
A trial of SHR-A1811 for HER2-positive gastric cancer
This trial tests a new drug, SHR-A1811, for people with HER2-positive stomach or gastroesophageal junction cancer that has worsened after initial treatment. It aims to see if this drug can help when standard anti-HER2 therapy stops working.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07870785Recruiting
Comparing viewing range of two progressive lenses in older adults
This study tests two types of progressive lenses (which help you see at different distances) to see how they affect your field of vision. It may help you find glasses that work better for daily tasks like reading and using a computer.
Seville, AndalusiaAges 52–67 - NCT06178120Recruiting
Study of disease progression in women with X-linked adrenoleukodystrophy
This study follows women with a genetic condition called X-linked adrenoleukodystrophy (ALD) over time to see how the disease progresses. It includes annual check-ups and MRI scans of the brain and spinal cord to monitor changes.
ParisAges 18 years+ - NCT04739319Recruiting
Study of age-related macular degeneration changes
This study looks closely at how age-related macular degeneration (AMD) develops and changes over time by taking detailed eye measurements. It may help researchers better understand disease progression, especially for people who already have AMD.
East Melbourne, VictoriaAges 18 years+ - NCT07874321RecruitingPhase 2
Study of MRG003 for advanced thyroid cancer that has progressed on current therapy
This trial tests an investigational drug called MRG003 added to your current treatment for advanced thyroid cancer that has stopped responding. It may help people with specific types of thyroid cancer and certain tumor markers.
Guangzhou, GuangdongAges 18–80
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Common questions
- Are there clinical trials for progression?
- Yes. Clin2 currently lists 716 recruiting progression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a progression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a progression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.