Clinical trials
Prolapse clinical trials
Below are recruiting prolapse clinical trials, each written for real people, not researchers. We’re tracking 84 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07384871Recruiting
3D Ultrasound Study of Mitral Valve Shape and Function
This study uses 3D ultrasound images to better understand heart valve shape and function in people with a leaky mitral valve who are scheduled for valve repair surgery. The goal is to improve how doctors plan and perform the surgery.
San Donato MilaneseAges 18 years+ - NCT07306715Recruiting
Laparoscopic surgery for dropped uterus: mesh vs no mesh
This trial compares two types of laparoscopic surgery to fix a dropped uterus (pelvic organ prolapse) — one using a mesh support and one without. It's for women who are ready to have their uterus removed and want to see which approach works better.
Köseköy, KocaeliAges 40–80 - NCT07067645Recruiting
Vaginal length after hysterectomy: comparing two closure methods
This trial compares two ways of closing the vagina after a hysterectomy for severe uterine prolapse to see which method keeps more vaginal length. It may help women who want to preserve vaginal depth after surgery.
IstanbulAges 35–65 - NCT07030426RecruitingPhase 3
Vaginal estrogen before and after prolapse surgery
This trial tests whether using vaginal estrogen before and after prolapse surgery helps improve recovery and long-term results. Women having apical suspension surgery (to support the top of the vagina) may benefit.
St. John's, Newfoundland and LabradorAges 18 years+ - NCT06954701Recruiting
Testing a new pessary for vaginal prolapse
This study tests a new, adjustable pessary for people with pelvic organ prolapse. If you already use a pessary and it works for you, this new device might be a better fit.
Edmonton, AlbertaAges 18 years+ - NCT06805006Enrolling by invitation
i-Stitch for pelvic organ prolapse support surgery
This study tests a device called i-Stitch for women having surgery to fix pelvic organ prolapse. It may help repair the pelvic area by securing the vagina in place with a special tool.
Munich, BavariaAges 18 years+ - NCT06754046Recruiting
Bulking vs. sling for stress incontinence with prolapse repair
This study compares two treatments for stress urinary incontinence (leaking urine when you cough or sneeze) done at the same time as surgery to fix a dropped bladder or uterus. One treatment is a small gel injection (bulking), the other is a sling procedure that supports the urethra.
Cleveland, OhioAges 18 years+ - NCT05631730RecruitingPhase 3
Flecainide plus metoprolol vs metoprolol alone for rhythm control
This trial studies whether adding flecainide to metoprolol can better reduce dangerous heart rhythm problems in people with mitral valve prolapse. It also checks safety and side effects compared with metoprolol alone.
OsloAges 18 years+ - NCT04547816RecruitingPhase 3
Non-surgical treatment for constipation-related prolapse in women
This study tests whether a non-surgical (“conservative”) approach can improve constipation-related bowel problems in women who have a mild-to-moderate rectal bulge from pelvic organ prolapse. It may help by addressing how the rectum and pelvic floor work during bowel movements.
MoscowAges 18–70 - NCT06341166Recruiting
Predicting heart scarring in mitral valve prolapse
This study looks at people with mitral valve prolapse (a common heart valve condition) to see if doctors can predict who might have scar tissue in their heart muscle. If you have this condition, joining could help improve understanding of your heart health.
Milan, MilanAges 18 years+ - NCT03764852Recruiting
Tests outpatient surgery for pelvic organ prolapse with double mesh
This study checks whether an outpatient (same-day) approach to a specific prolapse repair surgery is safe and practical, using a double-mesh method with or without robotic help. You may be offered the surgery under guidance of the study team if you meet the health and medical safety criteria.
ClamartAges 40–80 - NCT05602246Recruiting
Compare two surgeries for vaginal bulging
This trial tests whether one type of vaginal wall repair works better than another surgery for women with vaginal bulging (anterior prolapse). It may help find the safest and most effective operation to reduce symptoms.
Hradec KrálovéAges 50 years+ - NCT05569980Enrolling by invitation
Study of rectal prolapse surgery in the Nordic region
This study looks at people who are having surgery for rectal prolapse. The goal is to learn more about outcomes and care for patients after surgery.
Aarhus NAges 18 years+ - NCT04378400Enrolling by invitation
Check outcomes after laparoscopic sacrocolpopexy surgery
This study looks at short-term complications and longer-term results after laparoscopic sacrocolpopexy done at the study unit. It may help the clinic understand how well the surgery is working and how to improve care, based on follow-up questionnaires and check-ins.
LeuvenAges Any age - NCT04190602Recruiting
Registry study for NeoChord artificial mitral valve chord
This study keeps track of people who had NeoChord treatment to help understand how well it works in everyday care. You may be included if you had a certain type of mitral valve leakage (regurgitation) and the procedure happened after 2016.
BonnAges 18 years+ - NCT05778552Recruiting
Home pelvic floor training follow-up for bladder and pelvic support issues
This study checks how well a home-based pelvic muscle training program works over the medium and long term for people with stress urine leakage and pelvic support problems. It may help you learn whether this at-home exercise plan improves bladder control and comfort over time.
TaipeiAges 18 years+ - NCT03962023Recruiting
Study of heart ultrasound features in mitral valve leakage
This study looks at how findings on a standard heart ultrasound (transthoracic echocardiography) can predict outcomes for adults with mitral valve leakage caused by valve prolapse. It may help doctors better understand which ultrasound features matter most, using past and future medical records.
Lomme, NordAges 18 years+ - NCT06607471Recruiting
Study on non-ischemic heart muscle diseases
This study looks at different types of heart muscle diseases that are not caused by blocked arteries (non-ischemic cardiomyopathies). It aims to better understand how to diagnose, predict outcomes, and treat these conditions by gathering information from many patients over time.
Milan, MilanoAges 18 years+ - NCT07730970Recruiting
Deep muscle relaxation and diet for vNOTES hysterectomy
This study tests whether deep muscle relaxation and a special low-residue diet improve the surgical view during vNOTES hysterectomy for non-cancer conditions. It aims to make the procedure safer and easier for the surgeon.
Istanbul, KARTALAges 18 years+ - NCT07692789Recruiting
Phone reminders before a bladder test
This study tests if phone calls and MyChart reminders help women prepare for a urodynamics test (a test that checks how your bladder works). You may be able to take part if you are a woman scheduled for this test at certain Ohio State clinics.
Columbus, OhioAges 18 years+ - NCT07601282Recruiting
Predicting Incontinence Risk After Pelvic Floor Surgery
This study helps doctors predict which patients may develop urinary incontinence (leakage) after surgery to repair pelvic organ prolapse (when pelvic organs drop into the vaginal canal). By identifying risk factors early, doctors may be able to better prepare patients and prevent this complication.
Shanghai, Shanghai MunicipalityAges 20–90 - NCT07596498Recruiting
Comparing two surgical approaches for severe vaginal prolapse
This study compares two minimally invasive surgical techniques to repair severe dropping of the uterus or vaginal vault (the top of the vagina). Both procedures use small cameras and instruments, and the trial aims to understand which approach works better and how quickly surgeons learn each technique.
Cairo, AbbasiaAges 40–75 - NCT05335317Recruiting
Low-intensity laser for vaginal thinning and irritation
This trial studies whether a low-intensity nanosecond laser can improve vaginal atrophy (vaginal thinning) and related symptoms. It may help reduce discomfort for people who fit the study conditions and can complete the required visits and procedures.
Nizhny NovgorodAges 40–75 - NCT07544667Recruiting
Poly-L-Lactic Acid Injections for Vaginal Tissue Support
This trial tests whether injections of a biocompatible filler (Poly-L-Lactic Acid, also called Sculptra) can help reduce bulging or heaviness in the vaginal area caused by pelvic organ prolapse. The filler is designed to strengthen vaginal tissue and may improve symptoms without surgery.
Durham, North CarolinaAges 21 years+
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Common questions
- Are there clinical trials for prolapse?
- Yes. Clin2 currently lists 84 recruiting prolapse studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prolapse trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prolapse trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.