Clinical trials
Prolapse clinical trials
Below are recruiting prolapse clinical trials, each written for real people, not researchers. We’re tracking 89 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04169152Recruiting
Treatment for internal hemorrhoids and rectal prolapse
This trial studies a procedure (“CAES”) for people with internal hemorrhoids (grades I–III) and/or rectal prolapse. It may help reduce symptoms and improve bleeding or discomfort, as long as your condition fits the study’s safety rules.
Nanjing, JiangsuAges Any age - NCT04547816RecruitingPhase 3
Non-surgical treatment for constipation-related prolapse in women
This study tests whether a non-surgical (“conservative”) approach can improve constipation-related bowel problems in women who have a mild-to-moderate rectal bulge from pelvic organ prolapse. It may help by addressing how the rectum and pelvic floor work during bowel movements.
MoscowAges 18–70 - NCT05586984Recruiting
Compare two uterus-support surgeries for uterine prolapse
This trial compares two surgical ways to support the uterus without removing it: a vaginal approach versus a laparoscopic (camera) approach. It may help you choose the method that best improves uterine prolapse symptoms and function.
TainanAges 21 years+ - NCT05602246Recruiting
Compare two surgeries for vaginal bulging
This trial tests whether one type of vaginal wall repair works better than another surgery for women with vaginal bulging (anterior prolapse). It may help find the safest and most effective operation to reduce symptoms.
Hradec KrálovéAges 50 years+ - NCT05631730RecruitingPhase 3
Flecainide plus metoprolol vs metoprolol alone for rhythm control
This trial studies whether adding flecainide to metoprolol can better reduce dangerous heart rhythm problems in people with mitral valve prolapse. It also checks safety and side effects compared with metoprolol alone.
OsloAges 18 years+ - NCT05918367Recruiting
Registry for surgery to fix pelvic organ prolapse
This is a patient registry study for people having a laparoscopic or robotic operation called ventral mesh rectopexy to treat posterior pelvic organ prolapse. It mainly collects information through questionnaires to better understand outcomes and care, rather than testing a new drug.
BrusselsAges 18 years+ - NCT06341166Recruiting
Predicting heart scarring in mitral valve prolapse
This study looks at people with mitral valve prolapse (a common heart valve condition) to see if doctors can predict who might have scar tissue in their heart muscle. If you have this condition, joining could help improve understanding of your heart health.
Milan, MilanAges 18 years+ - NCT06738537Recruiting
Choosing treatment for mitral valve prolapse
This study looks at how to involve you in decisions about treating mitral valve prolapse, a condition where a heart valve doesn't close tightly. It aims to find the best way to help you and your doctor choose the right treatment.
Los Angeles, CaliforniaAges 21 years+ - NCT06754046Recruiting
Bulking vs. sling for stress incontinence with prolapse repair
This study compares two treatments for stress urinary incontinence (leaking urine when you cough or sneeze) done at the same time as surgery to fix a dropped bladder or uterus. One treatment is a small gel injection (bulking), the other is a sling procedure that supports the urethra.
Cleveland, OhioAges 18 years+ - NCT07067645Recruiting
Vaginal length after hysterectomy: comparing two closure methods
This trial compares two ways of closing the vagina after a hysterectomy for severe uterine prolapse to see which method keeps more vaginal length. It may help women who want to preserve vaginal depth after surgery.
IstanbulAges 35–65 - NCT07213635RecruitingPhase 4
Numbing injection for pain after hysterectomy for prolapse
This trial tests whether a numbing injection into the cervix can reduce the need for opioid pain medicine after vaginal hysterectomy for prolapse. It aims to find a safer, effective pain control option.
Raleigh, North CarolinaAges 18 years+ - NCT07384871Recruiting
3D Ultrasound Study of Mitral Valve Shape and Function
This study uses 3D ultrasound images to better understand heart valve shape and function in people with a leaky mitral valve who are scheduled for valve repair surgery. The goal is to improve how doctors plan and perform the surgery.
San Donato MilaneseAges 18 years+ - NCT07642180Recruiting
Pelvic Floor Exercises for Uterine Prolapse
This study tests whether special pelvic floor exercises can help reduce uterine prolapse (when the uterus drops into the vagina). You would do two types of exercises—pelvic floor strengthening and core stability work—to see if they improve your symptoms.
Lahore, Punjab ProvinceAges 30–60 - NCT05569980Enrolling by invitation
Study of rectal prolapse surgery in the Nordic region
This study looks at people who are having surgery for rectal prolapse. The goal is to learn more about outcomes and care for patients after surgery.
Aarhus NAges 18 years+ - NCT06494982Recruiting
Vaginal flap plus mesh sling for prolapse
This trial tests a surgery that uses a small piece of your own vaginal tissue to help hold the top of the vagina in place with a mesh sling. It is for women who have both front and top vaginal prolapse that bulges outside the opening.
Saint PetersburgAges 45–80 - NCT06679621Recruiting
Telehealth to prepare Latinas for pelvic surgery
This study tests a telehealth program to help Hispanic women feel more prepared before surgery for a pelvic floor condition like prolapse or incontinence. The program is done over video or phone, so you don't have to travel to a clinic.
Birmingham, AlabamaAges 18 years+ - NCT05978414Recruiting
Jaw and Pelvis Connections in Women After Prolapse Surgery
This study looks at how the jaw joint and pelvis may be connected in women who have had surgery for pelvic organ prolapse and also have endometriosis. It aims to find new links that could help guide treatment.
PoznanAges 18–60 - NCT04829058Recruiting
Follow-up study for women who received mesh for prolapse surgery
This study is checking women’s outcomes after a specific prolapse surgery where a mesh material (GYNEMESH PS) was used. If you had this operation and can do follow-up visits, this study may help doctors better understand the mesh’s real-world safety and results.
North Wales, PennsylvaniaAges 21 years+ - NCT04560543Recruiting
Laparoscopic support after simple hysterectomy
This study looks at whether adding laparoscopic “support” after a planned hysterectomy can help prevent future pelvic organ prolapse or related problems. You may be eligible if you are having a specific type of hysterectomy and meet several medical and practical requirements.
BernAges 18 years+ - NCT04025047Recruiting
Follow-up study after trans-vaginal mesh pelvic surgery
This study follows people who have pelvic reconstructive surgery using a trans-vaginal mesh to learn about possible complications over time. It may help improve care by tracking outcomes for up to 36 months.
Beijing, Beijing MunicipalityAges 18 years+ - NCT03389542Recruiting
Early mitral valve repair versus watchful waiting
This trial compares doing mitral valve repair early versus closely monitoring without surgery in people who have severe leakage but no symptoms. It aims to see whether early repair helps prevent future heart problems.
AmiensAges 18–75 - NCT07084818Enrolling by invitation
Helping Pessary Users Manage Their Care at Home
This study tests a program to help women with pelvic organ prolapse who live in rural areas take better care of their pessary at home. You may join if you use a pessary for prolapse, have stage 2 or higher prolapse, and are not dealing with active infections or certain other conditions.
Lebanon, New HampshireAges 18 years+ - NCT03766048Recruiting
Preventive mesh surgery for stage 2 bladder-type prolapse
This trial studies whether a preventive laparoscopic mesh placed during pelvic surgery can reduce future problems for women with early (stage 2) prolapse affecting the bladder side. It may help prevent the prolapse from getting worse, but it also involves surgical risks and strict eligibility rules.
Clermont-FerrandAges 40–75 - NCT07082023Recruiting
Comparing two surgical methods for pelvic organ prolapse
This trial compares two minimally-invasive surgical techniques to fix pelvic organ prolapse. It aims to see which method works better and has fewer side effects.
IstanbulAges 18–75
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Common questions
- Are there clinical trials for prolapse?
- Yes. Clin2 currently lists 89 recruiting prolapse studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prolapse trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prolapse trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.