Clinical trials
Prosthetic Infection clinical trials
Below are recruiting prosthetic infection clinical trials, each written for real people, not researchers. We’re tracking 31 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06771050RecruitingPhase 4
Antibiotics and surgery for hip and knee joint infections
This trial tests different antibiotic types and durations, plus surgical approaches, for people with a current joint infection in a hip or knee. It aims to find the best way to treat the infection and prevent it from coming back.
Garran, Australian Capital TerritoryAges 18 years+ - NCT06172010RecruitingPhase 4
Rifampicin plus antibiotics for staph joint replacement infection
This study tests whether adding the antibiotic rifampicin to standard treatment works better than standard treatment alone for staph infections in hip or knee replacements. The goal is to find a more effective way to clear the infection and avoid more surgeries.
Leiden, Zuid HollansAges 18 years+ - NCT06670885Enrolling by invitation
New DNA test for joint replacement infections
This trial uses advanced molecular methods to better diagnose infections in hip or knee replacement joints. The goal is to find infections more accurately so you can get the right treatment sooner.
Milan, MilanoAges 18 years+ - NCT05902221RecruitingPhase 3
Rifampicin add-on for knee, hip, or shoulder implant infections
This Phase 3 trial tests whether adding rifampicin improves outcomes for implant infections caused by a specific germ (Cutibacterium acnes) after surgery. If you have such an infection and the germ is susceptible, you may be able to receive a rifampicin-based treatment plan.
AnnecyAges 18 years+ - NCT02801253Recruiting
Study of infections around hip, knee, or shoulder implants
This study follows people who have an infection around a hip, knee, or shoulder implant (prosthesis). It uses standard infection tests (like cultures and blood tests) to confirm the diagnosis and better understand this problem after surgery.
Paris, Île-de-France RegionAges 18 years+ - NCT06293352Recruiting
Comparing two antibiotic spacers for knee infection
This trial compares two types of antibiotic spacers for people with a long-term knee replacement infection. It tests whether a spacer made entirely of antibiotic cement or one with a metal core works better to treat the infection before a new knee replacement.
Chicago, IllinoisAges 18 years+ - NCT03307109Recruiting
Quality of life study for adults with an infected joint implant
This study looks at how treatment affects quality of life for adults who have an infection around a joint implant. You may be asked to complete questionnaires to understand symptoms and daily well-being.
LyonAges 18 years+ - NCT07107685Recruiting
Joint replacement infections in critical care patients
This trial looks at infections in hip, knee, or shoulder replacements in people who needed critical care and later passed away. It aims to learn from their medical information to better prevent and treat similar infections.
Paris, FranceAges 18 years+ - NCT05000723Recruiting
Follow-up for hip joint infection after joint replacement
This study checks what happens over the long term for people who had an infection around a replaced (prosthetic) hip. It mainly helps doctors understand recovery and long-term outcomes after treatment.
LeuvenAges 18 years+ - NCT07788404Recruiting
Study of rifampin levels in patients with bone or joint staph infections
This study looks at how the antibiotic rifampin behaves in the body when used to treat staph infections in bones or joints. It may help doctors better dose the drug for future patients.
Paris, ParisAges 18 years+ - NCT06919913Recruiting
Probiotics for joint infection surgery
This study tests if taking probiotics before and after surgery can help your immune system fight infection in a hip or knee replacement. You would be given a probiotic or a placebo alongside your standard treatment.
New York, New YorkAges 18–90 - NCT06636669Enrolling by invitationPhase 4
Probiotics to prevent repeat joint infection after replacement surgery
This trial tests whether taking probiotics can help prevent another infection in people who have had a hip or knee replacement that became infected. If you are scheduled for revision surgery due to an infection, this study may be a good fit.
Boston, MassachusettsAges 18–90 - NCT05660733Recruiting
Study of infections of the aorta and large arteries
This trial studies how to care for infections that involve the aorta or other large blood vessels. If you have signs and test results that fit this diagnosis, you may be invited to help researchers better understand the condition and treatments.
Vandœuvre-lès-Nancy, LorraineAges 18 years+ - NCT06554041Recruiting
How gum tissue reacts to different dental crown materials
This study compares how different dental crown materials affect your gums around dental implants. It may help you if you have several missing teeth and already have healed implants in good bone.
VilniusAges 18 years+ - NCT05169229RecruitingPhase 2
Antibiotic bone graft to prevent infection in hip replacement
This trial tests whether adding antibiotics to the bone graft used during hip replacement surgery can lower the risk of infection. It may help people who need a bone graft as part of their hip replacement.
Linköping, Region ÖstergotlandAges 18 years+ - NCT04724603Recruiting
Review of side effects after phage treatment for bone infections
This study looks back at people who were treated with phage therapy for a bone, joint, or implant infection and later had a side effect. It aims to better understand how safe phage therapy is in real-life use.
LyonAges Any age - NCT04650607Recruiting
Phage therapy safety check in serious infection patients
This study checks the safety of using phage therapy (viruses that target certain bacteria) in adults being treated for serious infections. If you meet the safety rules, your care team may enroll you to help confirm phage treatment is safe.
LyonAges 18 years+ - NCT07214311RecruitingPhase 2/Phase 3
A trial of PLG0206 to prevent knee joint infection after surgery
This trial tests if a new drug called PLG0206 can stop a knee joint infection from coming back after a surgery called DAIR. DAIR cleans the infected area and keeps the artificial knee in place, and this study wants to see if adding PLG0206 helps prevent the infection from returning.
Sarasota, FloridaAges 18–80 - NCT04672525RecruitingPhase 3
Rifabutin versus rifampicin for knee or hip staph implant infection
This Phase 3 trial compares two antibiotics—rifabutin and rifampicin—for treating staphylococcal (staph) infections around hip or knee joint implants when the implant is kept in place after cleaning (DAIR). It aims to see which drug works better to stop the infection from coming back.
AmiensAges 18 years+ - NCT04858217Recruiting
Testing blood and joint fluid tests for hip or knee infection
This trial checks how accurate certain blood tests and joint-fluid (synovial) tests are at identifying infections around hip or knee replacements. It also looks at whether these tests are worth the cost, to help doctors choose the best next step.
BolognaAges 18 years+ - NCT06737809Recruiting
Silver-coated hip revision for infection
This trial tests a new silver-coated hip implant for people who need a revision due to a chronic infection around the joint. It may help control the infection while replacing the implant.
BerlinAges 18 years+ - NCT07406893Recruiting
Reducing Infection Risk in Shoulder Replacement Surgery
This trial tests whether a special gel (Prontosan) applied during shoulder replacement surgery can reduce the risk of infection. It is for men having their first shoulder replacement.
St Louis, MissouriAges 18 years+ - NCT07324954RecruitingPhase 1
Methylene blue for knee replacement surgery
This study tests if using a blue dye called methylene blue during knee replacement surgery can help doctors see and clean out infections better. It may help people having a first-time knee replacement or those with an infected knee replacement.
Miami, FloridaAges 18 years+ - NCT05642013Recruiting
Short interval exchange surgery for infected hip or knee implants
This study compares how to replace an infected hip or knee implant using a two-step surgery with a shorter waiting time. It aims to reduce the time between surgeries while still safely treating the infection.
MontpellierAges 18 years+
Hear when a new Prosthetic Infection trial opens
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Common questions
- Are there clinical trials for prosthetic infection?
- Yes. Clin2 currently lists 31 recruiting prosthetic infection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prosthetic infection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prosthetic infection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.