Clinical trials
Pulmonary Hypertension clinical trials
Below are recruiting pulmonary hypertension clinical trials, each written for real people, not researchers. We’re tracking 232 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04756076Recruiting
Study heavy metal levels in pulmonary hypertension patients
This study looks at whether heavy metals in the body—and an imbalance of important minerals—are different in people with pulmonary arterial hypertension. It may help researchers understand possible causes and targets for future treatments.
Louisville, KentuckyAges 18 years+ - NCT05340023Recruiting
Test using lung scan patterns to diagnose a heart-lung condition
This study looks at patterns from specialized lung scan tests to help diagnose chronic thromboembolic pulmonary hypertension (a long-term problem with blood flow in the lungs after blood clots). If your results suggest this condition and you need a procedure to check heart pressure, you may be asked to join so the researchers can improve diagnosis.
Saint-EtienneAges 18 years+ - NCT05610631Recruiting
Switzerland heart-lung pressure registry for people with PH
This is a registry that collects information from people who have pulmonary hypertension (high blood pressure in the lungs). It helps researchers better understand the condition and may support future studies.
ZurichAges Any age - NCT06454838Recruiting
Exercise and blood vessel health in children with pulmonary hypertension
This study looks at how exercise affects the lungs, blood vessels, and oxygen use in children with pulmonary arterial hypertension (high blood pressure in the lungs). It compares them to healthy children to understand how the condition impacts the body.
Ankara, ÇankayaAges 6–18 - NCT06804122Recruiting
Exercise rehab for pulmonary arterial hypertension
This trial tests a supervised exercise program for people with pulmonary arterial hypertension (PAH), a type of high blood pressure in the lungs. It aims to see if regular exercise can improve your daily function and quality of life.
Tampere, PirkanmaaAges 18 years+ - NCT06872112RecruitingPhase 1
Artesunate for pulmonary arterial hypertension safety study
This trial tests if artesunate, a malaria drug, is safe and tolerable for people with pulmonary arterial hypertension (PAH). It may offer a new treatment option for PAH patients whose symptoms persist despite using two or more standard therapies.
Stanford, CaliforniaAges 18–60 - NCT07140484RecruitingPhase 4
Sotatercept for pulmonary arterial hypertension
This study tests a new medication called sotatercept for people with pulmonary arterial hypertension (PAH) who are already on at least two other PAH treatments. The goal is to see if adding sotatercept can improve symptoms and exercise ability.
Edmonton, AlbertaAges 18 years+ - NCT07149935Recruiting
Exercise training for pulmonary arterial hypertension
This study tests whether a special exercise training program can help people with pulmonary arterial hypertension (PAH) feel better and stay stable. If you have mild-to-moderate PAH and are on stable medication, you may be able to join.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07366879Recruiting
Exercise program for newly diagnosed pulmonary hypertension
This study tests whether a home-based exercise program, added to your regular medications, can help people who are newly diagnosed with pulmonary arterial hypertension feel better and improve their daily function.
GlasgowAges 18 years+ - NCT01712620RecruitingPhase 2
Spironolactone for pulmonary arterial hypertension in stable patients
This trial studies whether spironolactone can improve pulmonary arterial hypertension, a disease that makes the blood vessels in the lungs work too hard. You may be eligible if your condition is confirmed by specific heart-lung pressure tests and your medication plan has been stable for at least 4 weeks.
Bethesda, MarylandAges 18–100 - NCT01347216Recruiting
COMPERA study for lung vessel pressure medicines
This study follows people with different types of high blood pressure in the lungs (pulmonary hypertension) to see how starting specific lung blood vessel medicines affects outcomes. It may help improve how clinicians choose and monitor treatment over time.
LeuvenAges 1 week+ - NCT07457762Recruiting
Reminder app for pulmonary hypertension inhaler
This study tests if a smartphone app can help people with pulmonary arterial hypertension (PAH) stick to their inhaled iloprost treatment. It is for adults already on this treatment at a specific clinic in Brazil.
São Paulo, São PauloAges 18 years+ - NCT06931886Enrolling by invitation
Breathing training for pulmonary hypertension
This trial tests if special breathing exercises can help people with pulmonary hypertension. You may join if your condition is stable and you haven't smoked in the last 10 years.
Tucson, ArizonaAges 18 years+ - NCT02249923Recruiting
Children with pulmonary hypertension registry in Spanish or English
This registry study collects information from children and families affected by pulmonary hypertension to better understand the condition. It may help researchers track outcomes over time and improve future care.
Palo Alto, CaliforniaAges 1 day–21 years - NCT07318597RecruitingPhase 2
A study of an experimental drug for pulmonary arterial hypertension
This trial tests a new medication called REGN13335 for people with pulmonary arterial hypertension (PAH). It aims to see if the drug can improve symptoms and function compared to standard care alone.
Aurora, ColoradoAges 18 years+ - NCT05745961Recruiting
Measuring a lung protein in pulmonary artery hypertension
This study measures how much of a specific lung protein (TSPO) is present in people with pulmonary artery hypertension. The results may help researchers better understand the disease and guide future treatments.
LondonAges 25–75 - NCT07365332RecruitingPhase 3
IKT-001 for pulmonary arterial hypertension
This study tests a new medicine called IKT-001 for people with pulmonary arterial hypertension (PAH). It aims to see if IKT-001 helps improve exercise ability and other symptoms when added to current PAH therapies.
Louisville, KentuckyAges 18–75 - NCT07481981RecruitingPhase 3
Study of once-daily inhaled TPIP for pulmonary arterial hypertension
This trial tests an inhaled medication (TPIP) that opens blood vessels in the lungs to help you breathe easier and be more active. It is for people with PAH who are already on stable treatment and have moderate symptoms.
Santa Barbara, CaliforniaAges 18–75 - NCT07561034Recruiting
Home Exercise Program for Pulmonary Hypertension and Lung Disease
This study tests whether daily home exercises can help people with pulmonary hypertension (high blood pressure in the lungs) combined with interstitial lung disease (scarring of lung tissue). Researchers will send you daily messages to support your exercise routine and see if it improves your symptoms and quality of life.
Rochester, New YorkAges 18 years+ - NCT04078243Recruiting
Trial setup and testing in adults with pulmonary hypertension
This study tests new “trial tools” and designs for running early research in people with pulmonary hypertension. If you qualify, you may be asked to do extra trial-related procedures to help researchers test the process safely and smoothly.
Sheffield, South YorkshireAges 18 years+ - NCT04145024Recruiting
Pulmonary hypertension registry and blood sample biobank
This study keeps a health registry and biobank for people diagnosed with pulmonary hypertension using a specific heart test. It helps researchers better understand the condition and may improve future care.
GiessenAges Any age - NCT04898114RecruitingPhase 1/Phase 2
Inhaled magnesium and sildenafil for newborn lung blood pressure
This study tests whether breathing in magnesium sulfate and giving sildenafil can improve breathing and lung blood vessel pressure in newborns with persistent pulmonary hypertension. It may help newborns who are having trouble oxygenating despite being on a ventilator.
SohagAges 6 hours–3 days - NCT07151768Recruiting
Validating a risk score for lung disease patients with pulmonary hypertension
This study is testing whether a new risk score can better predict outcomes for people who have both chronic lung disease and pulmonary hypertension (high blood pressure in the lungs). If you qualify, the researchers will follow your health over time to see how well the score works.
Philadelphia, PennsylvaniaAges 18–99 - NCT07311135Recruiting
Smartwatch Oxygen Accuracy in Pulmonary Hypertension
This study tests how well a smartwatch measures oxygen levels in people with pulmonary hypertension during a 6-minute walk. It could help find a simpler way to check oxygen at home.
GlasgowAges 18 years+
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Common questions
- Are there clinical trials for pulmonary hypertension?
- Yes. Clin2 currently lists 232 recruiting pulmonary hypertension studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulmonary hypertension trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulmonary hypertension trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Pulmonary Arterial Hypertension
- Chronic Thromboembolic Pulmonary Hypertension
- Pulmonary Artery Hypertension
- Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
- Idiopathic Pulmonary Arterial Hypertension
- Pulmonary Hypertension Due to Lung Diseases and Hypoxia
- Pulmonary Hypertension (Diagnosis)
- Pulmonary Hypertension Due to Left Heart Disease
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.