Clinical trials
Radical Cystectomy clinical trials
Below are recruiting radical cystectomy clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06783855Recruiting
Bladder cancer surgery with a new suspension technique
This trial tests a new surgical technique called uretheroileal suspension during bladder removal surgery for people with muscle-invasive bladder cancer or certain high-risk non-muscle-invasive bladder cancers that have not responded to other treatments.
SohagAges 18–80 - NCT05792722Recruiting
Testing a prostate-sparing bladder surgery for bladder cancer
This trial studies whether a “prostate-sparing” radical cystectomy is safe and effective for bladder cancer patients who are having surgery. It aims to see if this approach can treat bladder cancer while reducing prostate-related side effects.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06170177Recruiting
Life after bladder removal surgery study
This study looks at how people feel and their health after having their bladder removed. It aims to understand quality of life after this surgery.
Milan, MIAges 18 years+ - NCT06184516RecruitingPhase 2
Bladder cancer study: testing a tool to see if womb and ovaries can be saved
This trial is testing a decision-making tool to help women with bladder cancer choose whether to keep their uterus, ovaries, and other pelvic organs during bladder removal surgery. It may help maintain quality of life after surgery.
Gainesville, FloridaAges 18–99 - NCT04900558Recruiting
Study outcomes after robotic bladder removal surgery
This trial follows adults who are planning to have a robotic radical cystectomy (surgery to remove the bladder and surrounding tissue) to learn what outcomes to expect. If you choose to join and meet the basics, it may help your team compare results and improve care for future patients.
Florence, TuscanyAges 18 years+ - NCT05067101Recruiting
Compare two bladder cancer surgeries in men
This trial compares two types of bladder surgery to see which works better for certain men with bladder cancer. It may help you and your doctors choose the safest option that controls the cancer while preserving quality of life.
Guangzhou, GuangdongAges 20 years+ - NCT07202819Recruiting
Chemotherapy and MRI before bladder surgery
This study looks at how well MRI scans can detect bladder cancer after chemotherapy, before surgery to remove the bladder. It may help doctors know if the chemo is working.
Asyut, Asyut GovernorateAges 18 years+ - NCT06190197RecruitingEarly Phase 1
Testing antibiotics before bladder removal surgery
This trial tests whether giving preventive antibiotics before bladder removal surgery reduces infections. If you have muscle-invasive bladder cancer and are having your bladder removed, you may be able to join.
Minneapolis, MinnesotaAges 18 years+ - NCT06595446Recruiting
Timing of stent removal after bladder cancer surgery
This study looks at whether removing a small tube (stent) placed during bladder surgery earlier or later helps recovery. It is for patients having a specific type of bladder removal surgery that creates a new way for urine to leave the body.
London, OntarioAges 18 years+ - NCT06427824Recruiting
Health tests for older adults with bladder cancer before bladder removal
This study looks at how a series of health tests (called a comprehensive geriatric assessment) can help doctors plan care for older adults with bladder cancer who are having their bladder removed. The goal is to improve recovery and quality of life.
Chicago, IllinoisAges 65 years+ - NCT07225205Recruiting
Home IV fluids after bladder removal surgery
This trial tests if giving IV fluids at home after bladder removal surgery is safe and helpful. It aims to reduce dehydration and hospital visits after you go home.
Baltimore, MarylandAges 18 years+ - NCT03193970Recruiting
Study recovery after bladder removal surgery
This trial looks at how patients recover after radical cystectomy, a surgery that removes the bladder for bladder cancer. It will study recovery patterns to help understand what recovery may look like and possibly improve care.
Stanford, CaliforniaAges 18 years+ - NCT07762586RecruitingPhase 2
Neoadjuvant chemotherapy for muscle-invasive bladder cancer
This study looks at how well a standard chemotherapy given before surgery works for muscle-invasive bladder cancer. It aims to see if higher responses lead to better outcomes.
New Brunswick, New JerseyAges 18–90 - NCT07579195RecruitingPhase 1/Phase 2
Consolidation therapy after EV + pembro in bladder cancer
This trial tests whether adding radiation therapy or bladder-removal surgery (consolidation) after EV + pembrolizumab helps control muscle-invasive bladder cancer that has spread. It is for people whose cancer responded to the initial drug combination.
Seattle, WashingtonAges 18 years+ - NCT06373055Recruiting
Predicting chemo response in bladder cancer with gene mapping
This trial uses a new technology called spatial transcriptomics to study how bladder cancer tumors respond to chemotherapy before surgery. It aims to find patterns that predict which patients will benefit from treatment.
SeoulAges 18–80 - NCT05089994Recruiting
Pain-control injections after bladder surgery
This trial compares two different injection techniques to reduce pain after radical cystectomy (bladder removal surgery). It may help find which approach gives better pain relief with fewer side effects.
AsyutAges 40–70 - NCT07693959RecruitingPhase 3
RC48 plus gemcitabine before bladder cancer surgery
This trial tests a combination of an antibody-drug conjugate (RC48) plus chemotherapy (gemcitabine) given before bladder removal surgery. It is for people with HER2-positive bladder cancer that has grown into the muscle layer.
Hefei, AnhuiAges 18–75 - NCT06806059Recruiting
Exercise before bladder removal surgery study
This study looks at whether being active before bladder cancer surgery helps you recover with fewer problems. It tests how physical activity before surgery affects your health afterwards.
Munich, BavariaAges 18 years+ - NCT07048457RecruitingPhase 2
Surgery for metastatic bladder cancer after initial treatment
This trial tests whether removing the primary bladder tumor and any remaining metastatic spots after initial medication (enfortumab-vedotin) improves outcomes for people with a limited number of metastases (5 or fewer). It is for those whose cancer has responded or stabilized on treatment.
New Haven, ConnecticutAges 18 years+ - NCT03216525RecruitingPhase 3
Alvimopan vs placebo to reduce bowel slowdown after bladder surgery
This trial tests whether alvimopan, a medicine given around the time of bladder removal surgery, can help your bowels start working sooner after surgery compared with a placebo (inactive pill). It may help shorten recovery by reducing bowel-related side effects on an enhanced recovery plan.
Boston, MassachusettsAges 18–85 - NCT05204186Recruiting
AI Tool to Predict Health Outcomes After Bladder Removal Surgery
This study tests an artificial intelligence tool designed to predict how patients will recover after bladder cancer surgery. The AI analyzes existing medical information to help doctors better understand which patients might face complications based on their other health conditions.
Amiens, PicardieAges 18 years+ - NCT05790850Recruiting
Mindfulness and exercise plan before bladder surgery
This study tests whether a structured mindfulness and high-intensity exercise program before radical bladder surgery can help patients improve health and recovery. You may be asked to use monitoring devices and complete questionnaires during the study.
Charlottesville, VirginiaAges 18–90 - NCT06091124RecruitingPhase 2
Immunotherapy plus chemo before surgery for neuroendocrine bladder cancer
This trial tests a combination of an immunotherapy drug (adebrelimab) with two chemotherapy drugs (etoposide and cisplatin) given before surgery for a rare, aggressive type of bladder cancer called neuroendocrine carcinoma. The goal is to see if this approach can shrink the tumor and improve outcomes.
Nanjing, JiangsuAges 18–75 - NCT06263153RecruitingPhase 2
Futibatinib and durvalumab before bladder cancer surgery
This trial tests two drugs (futibatinib and durvalumab) given before bladder removal surgery for people with muscle-invasive bladder cancer who cannot take standard cisplatin chemotherapy. The goal is to see if the combination shrinks the tumor and improves outcomes.
Ann Arbor, MichiganAges 18 years+
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Common questions
- Are there clinical trials for radical cystectomy?
- Yes. Clin2 currently lists 26 recruiting radical cystectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radical cystectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radical cystectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.