Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,324 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06585007RecruitingPhase 3
Radiation for limited cancer growth in castration-resistant prostate cancer
This trial tests whether giving focused radiation to limited areas of cancer growth (up to 3 spots) can help control the disease in men with castration-resistant prostate cancer. You may be eligible if your cancer is growing slowly and you are already on hormone therapy.
LeuvenAges 18 years+ - NCT07242118Recruiting
Radiation therapy for older women with breast cancer
This trial tests a precise, high-dose radiation treatment (called SABR) for older women with early-stage breast cancer who choose not to have surgery. It aims to control the tumor with fewer side effects and may be an option if you have a small, ER+, HER2- tumor that hasn't spread to lymph nodes.
Kansas City, KansasAges 65 years+ - NCT07378631Recruiting
Radiation rectal injury subtypes and outcomes study
This study looks at different types of radiation rectal injury to understand how they affect recovery. It may help you if you have been diagnosed with this condition and are not currently undergoing cancer treatment.
Guangzhou, GuangdongAges 18–80 - NCT07227792Recruiting
Tongue-out radiation therapy for head and neck cancer
This trial tests if sticking your tongue out during radiation therapy can reduce side effects. It is for people with certain types of head and neck cancer who are getting radiation to the main tumor.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05687851RecruitingPhase 2
Cadonilimab plus radiation for locally advanced cervical cancer
This trial studies whether adding cadonilimab (an immune therapy) to standard radiation can improve treatment for locally advanced cervical cancer. It may help your immune system work better against the cancer while radiation shrinks it.
Chongqing, CHNAges 18 years+ - NCT03649048Recruiting
Weekly low-dose or high-dose cisplatin with radiation for head and neck cancer
This trial compares two cisplatin dosing schedules (weekly low-dose vs higher dose less often) given alongside radiation for certain head and neck cancers. It’s testing which schedule works well while keeping side effects manageable during planned, curative-intent radiation.
Hamilton, OntarioAges 18 years+ - NCT07348887Recruiting
Daily adaptive radiotherapy for head and neck cancer to spare salivary glands
This trial tests a new daily adaptive radiotherapy technique that aims to spare the submandibular salivary glands during head and neck cancer treatment. It may help reduce dry mouth after radiation.
Toronto, OntarioAges 18 years+ - NCT06373497RecruitingEarly Phase 1
Heart artery health after chest radiation using PET scan
This study looks at how radiation therapy to the chest affects the arteries in your heart. It uses a special PET scan (with a safe radioactive tracer) to check for early signs of inflammation or plaque buildup, which can help doctors find ways to protect your heart during cancer treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07346248Enrolling by invitation
Complications after pre-surgery treatment for advanced rectal cancer
This study looks at complications that happen after surgery in patients with advanced rectal cancer who got radiation or chemo-radiation before their operation. Researchers want to learn how different pre-surgery treatments affect recovery.
Rozzano, MilanAges 18 years+ - NCT03417336Recruiting
Radiation for prostate cancer using smaller, targeted doses
This trial studies a specific radiation schedule for prostate cancer (with an extra “boost” dose) and checks whether it works well and is tolerable. It may help people with higher-risk, localized prostate cancer by aiming at the cancer while limiting side effects to surrounding tissues.
DijonAges 18–85 - NCT07337161Recruiting
Radiation for skin cancer that spread to neck lymph nodes
This trial tests a focused radiation treatment after surgery for people with a common skin cancer (squamous cell carcinoma) that has spread to the lymph nodes in the neck or near the ear. The goal is to see if this approach can prevent the cancer from coming back.
London, OntarioAges 18 years+ - NCT07282483RecruitingPhase 2
Chinese medicine mouthwash for radiation mouth sores
This trial tests whether a traditional Chinese medicine mouthwash and oral liquid can help prevent or reduce mouth sores caused by radiation therapy for head and neck cancer. If you are getting radiation and are at risk for these painful sores, this study might offer you extra relief.
Chengdu, SichuanAges 18–65 - NCT06828380RecruitingPhase 2
Immunotherapy with or without radiation for liver cancer
This trial tests whether using immunotherapy alone works as well as immunotherapy combined with radiation for liver cancer that has spread into major blood vessels. The goal is to find the best treatment option for people with this specific type of advanced liver cancer.
GoyangAges 19 years+ - NCT06306638RecruitingPhase 1/Phase 2
Light therapy after radiation for inoperable airway tumors
This trial tests a new light-activated therapy (interstitial photodynamic therapy) after palliative radiation to shrink inoperable airway tumors and improve breathing. It is for people with solid cancers that block the airway from the outside and cannot be removed with surgery.
Buffalo, New YorkAges 18 years+ - NCT07125755RecruitingPhase 3
Comparing Chemo plus Radiation vs. Radiation Alone for Head and Neck Cancer
This trial tests whether adding chemotherapy to radiation therapy after surgery can help prevent head and neck cancer from coming back. It is for people who have certain risk factors after their surgery but no signs of cancer spread.
Guangzhou, GuangdongAges 18–70 - NCT06470503Enrolling by invitation
Exercise after radiation for bone metastases
This study tests whether a supervised exercise program helps people with cancer that spread to their bones feel stronger and move better after radiation treatment. It is designed for people who can walk independently and have stable bones.
Toronto, OntarioAges 18 years+ - NCT06823375RecruitingPhase 2
Radiation plus immunotherapy for liver cancer with major vein clot
This trial tests adding radiation (SBRT) to a combination of immunotherapy drugs (atezolizumab and bevacizumab) for people with liver cancer that has spread into the main portal vein. It aims to see if this approach can shrink tumors and improve outcomes.
Hong KongAges 18 years+ - NCT05040815RecruitingPhase 2
Sparing inner groin nodes during early anal cancer radiation
This trial tests whether a specific radiation plan that avoids treating the inner groin lymph nodes can treat early-stage anal cancer effectively while reducing side effects. Participants may also receive chemotherapy if they are eligible.
Edmonton, AlbertaAges 18 years+ - NCT06879964Recruiting
Radiation after surgery for high-grade skin cancer
This study looks at whether radiation therapy after surgery helps people with a high-grade type of skin cancer called squamous cell carcinoma. It may help doctors understand who benefits most from this additional treatment.
Pavia, PaviaAges 18 years+ - NCT06839547Recruiting
Testing a new drug with radiation for advanced breast cancer brain tumors
This study looks at how well a new anti-tumor drug works when given along with radiation therapy for people whose advanced breast cancer has spread to the brain. It may help the radiation work better and control the cancer longer.
BeijingAges 18 years+ - NCT05560659RecruitingPhase 2
SABR plus Lu-PSMA for limited prostate cancer spread
This trial studies whether adding Lu-PSMA therapy to targeted, high-precision radiation (SABR) can better control prostate cancer that has spread to a small number of lymph nodes or bones. It may help by treating both visible spots with the most accurate radiation and PSMA-targeted drug therapy.
St Leonards, New South WalesAges 18 years+ - NCT06840665RecruitingPhase 2
Radiation plus immunotherapy and chemo for rectal cancer
This trial combines a special type of radiation (MRI-guided adaptive radiotherapy) with an immunotherapy drug (PD-1 antibody) and chemotherapy (CAPOX) for locally advanced rectal cancer. The goal is to see if this combination can improve treatment outcomes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05798845RecruitingPhase 2
Toripalimab plus radiation before surgery for stage II–IIIA lung cancer
This trial studies whether adding toripalimab (an immunotherapy medicine) to radiation can improve outcomes for people with operable stage II to IIIA non-small cell lung cancer. It’s designed for cancers that can be fully removed with surgery, and it aims to see if this combination helps more than radiation alone/standard care.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06835725RecruitingPhase 2
Comparing two prostate radiation schedules for intermediate risk
This trial compares giving radiation in 2 treatments versus 5 treatments for prostate cancer that hasn't spread. It's for men with low or intermediate risk prostate cancer who are healthy enough to undergo a short course of targeted radiation.
Surrey, British ColumbiaAges 18 years+
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Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,324 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.