Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06659146Recruiting
Heat therapy with standard palliative radiation for cancer
This trial tests whether adding heat therapy (using a special lamp) to standard palliative radiation can help treat superficial tumors or lymph nodes that cannot be cured. It aims to improve symptom relief or tumor control for people with advanced cancer.
LondonAges 18 years+ - NCT06668038Recruiting
Second round of radiation for tumors that come back
This study tests a new way to plan a second course of radiation for cancer that has returned or spread to a few places. It uses special imaging software to make the treatment more precise and aims to improve outcomes.
AngersAges 18 years+ - NCT06636188Recruiting
AI Nurse Assistant to Reduce Distress During Cancer Radiation
This trial is testing a new AI-powered nurse assistant to help reduce distress during radiation therapy. It is for people with head and neck or laryngeal cancer who are about to start treatment and feel significant distress.
Hong Kong, Hong KongAges 18 years+ - NCT06635980RecruitingPhase 2
Radiation before or after breast cancer surgery
This trial compares two ways of giving radiation for breast cancer that has not spread: before or after surgery. It aims to see if giving radiation first might work as well or better.
Scottsdale, ArizonaAges 18 years+ - NCT06618703Recruiting
Brain radiation in childhood: early hormone check
This study follows children who had brain radiation for cancer to check for early hormone changes. It aims to catch and treat any hormone problems sooner.
AngersAges 4–18 - NCT06604533Recruiting
MRI-guided radiation for abdominal cancer spread
This trial tests if MRI-guided radiation can precisely target and treat cancer that has spread to a few spots in the abdomen (like the liver or lymph nodes). It's for people whose original cancer is under control and who have up to 5 small tumors in up to 2 body areas.
Darlinghurst, New South WalesAges 18 years+ - NCT04749134Recruiting
MRI tests to improve radiotherapy planning using healthy volunteers
This study uses MRI scans to help improve how radiotherapy is planned and delivered. You would be an adult volunteer without a patient diagnosis, and your scan may be checked for unexpected (incidental) findings.
ManchesterAges 16 years+ - NCT06605664RecruitingPhase 2
New MRI scan for liver cancer with radiation and immunotherapy
This trial tests a new type of MRI scan (hyperpolarized 13C-MRI) in people with liver cancer who are already receiving radiation therapy, atezolizumab (an immunotherapy), and bevacizumab (a targeted therapy). The goal is to see if the scan can help doctors better understand how the cancer responds to treatment.
Taoyuan City, TaiwanAges 18 years+ - NCT06601296RecruitingPhase 2
Radiation plus immunotherapy for metastatic kidney cancer
This trial tests whether combining radiation therapy with two types of immunotherapy (checkpoint inhibitors and an injectable drug called IMSA101) can help control metastatic kidney cancer that is only growing in a few spots. The goal is to see if this approach can shrink tumors and keep them from growing further.
Dallas, TexasAges 18 years+ - NCT06611306Recruiting
Targeted whole-brain radiation for breast cancer that spread to the brain
This trial tests a newer, more targeted way to give whole-brain radiation for breast cancer that has spread to the brain. It aims to see if this approach can be as effective while causing fewer side effects compared to the standard whole-brain radiation.
London, LondonAges 16–100 - NCT06601309RecruitingPhase 2
Study of treatments before surgery for esophageal cancer
This trial is testing different treatment combinations before surgery for people with locally advanced esophageal squamous cell carcinoma. The goal is to find which approach works best based on specific biomarkers like PD-L1 levels.
Fuzhou, FujianAges 18–75 - NCT06364579Recruiting
Measuring quality of life in anal cancer radiotherapy
This trial studies how patients feel during and after radiation therapy for anal cancer. It uses questionnaires to understand symptoms and well-being, helping doctors improve care.
Rome, LazioAges 18 years+ - NCT06586255RecruitingPhase 1
Immunotherapy and radiation after bladder cancer surgery
This trial tests whether adding radiation therapy to immunotherapy after bladder removal surgery can help prevent cancer from coming back. It's for people with advanced bladder cancer who have already started immunotherapy.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06574880RecruitingPhase 1/Phase 2
Radiation and Lutetium PSMA for locally advanced prostate cancer
This study tests a combination of focused radiation (SBRT) and a targeted radioactive drug (Lutetium PSMA) for men with prostate cancer that has spread to nearby lymph nodes or has high-risk features but has not yet reached distant organs. The goal is to see if this approach is safe and effective.
Cleveland, OhioAges 18 years+ - NCT06568705RecruitingPhase 2
Shorter adaptive radiation for early breast cancer
This trial tests a shorter, more targeted course of daily radiation for early-stage breast cancer. The radiation plan is adjusted each day to better fit your body, which may reduce side effects.
BeijingAges 35–70 - NCT06582446RecruitingPhase 2
AI-Personalized Radiation for High-Risk Prostate Cancer
This trial tests a new way to plan prostate cancer treatment using artificial intelligence and advanced imaging. It’s for people with high-risk prostate cancer that hasn’t spread to lymph nodes or other parts of the body, and who have not had prior radiation to the prostate.
LimassolAges 18 years+ - NCT05576480RecruitingPhase 2
Immunotherapy plus chemotherapy before surgery for rectal cancer without mismatch repair
This Phase 2 study tests penpulimab (an immunotherapy medicine) given with CAPEOX chemotherapy before surgery for rectal cancer that is “MSS” (not the mismatch-repair type). It aims to shrink the tumor and improve outcomes by treating before the operation.
Shanghai, None SelectedAges 18–75 - NCT06335251Recruiting
Radiation therapy for limb cancers
This study looks at how radiation therapy works for cancers in the arms or legs, including primary tumors and cancers that have spread there. It aims to understand the best ways to use radiation for treatment or pain relief.
MilanAges 18 years+ - NCT06557343Recruiting
Lung Cell Study After Chest Radiation
This study looks at cells from the lungs of people who developed lung inflammation after chest radiation for cancer. It aims to understand why some people get this reaction, which may help find better treatments.
EdinburghAges 18 years+ - NCT06560697Recruiting
Radiation boost for cervical cancer: SABR vs brachytherapy
This trial compares two types of radiation boost therapy for locally advanced cervical cancer: a newer, precise type called SABR versus the standard brachytherapy. The goal is to see if SABR works as well or better with fewer side effects.
Mexico City, TlalpanAges 18 years+ - NCT06207981RecruitingPhase 3
Comparing two treatment plans for advanced anal cancer
This trial tests if giving chemotherapy before standard chemoradiation works better than standard chemoradiation alone for people with locally advanced anal cancer that has not spread. It aims to improve treatment outcomes.
AgenAges 18 years+ - NCT06544798Enrolling by invitationPhase 2
Long-term follow-up of gene therapy for dry mouth
This study follows patients who previously received gene therapy for dry mouth caused by radiation. It aims to track long-term safety and any lasting benefits.
Gilbert, ArizonaAges 18 years+ - NCT06546969RecruitingPhase 1
Combination therapy for advanced bile duct cancer
This trial tests a combination of chemotherapy, immunotherapy, and heat therapy (hyperthermia) with a special radiation technique for advanced bile duct or gallbladder cancer that hasn't been treated before. It aims to see if this combination can help shrink tumors and improve outcomes.
Baltimore, MarylandAges 21 years+ - NCT06545747RecruitingPhase 3
MRI-guided radiation for advanced lung cancer
This trial tests a new way of giving radiation therapy for advanced lung cancer that cannot be surgically removed. It uses MRI scans to guide and adjust the radiation dose, which may help target the tumor more precisely and reduce side effects.
GuangzhouAges 18–75
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Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,308 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.