Clinical trials
Randomized Controlled Trial clinical trials
Below are recruiting randomized controlled trial clinical trials, each written for real people, not researchers. We’re tracking 602 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05591820Recruiting
Brief parent training for kids’ behavior at home
This study tests a short program that helps parents manage challenging behaviors in daily life. It may help families teach consistent routines and responses to behaviors like hyperactivity, impulsivity, inattention, or opposiveness.
Groningen, Provincie GroningenAges 2–11 - NCT05585411Recruiting
Pacemaker type test to reduce heart worsening and death risk
This study compares two pacemaker pacing strategies—left-sided “bundle branch area” pacing versus right-sided ventricular pacing. It aims to see which approach better prevents heart failure getting worse and reduces abnormal timing between heart chambers over time.
Bucheon-siAges 19 years+ - NCT05531474Recruiting
Bariatric surgery to lower future heart and stroke events
This trial looks at whether weight-loss surgery can reduce the chances of heart attack, stroke, or other serious heart problems in people at higher heart risk. You might be offered surgery and followed over time to see if cardiovascular events are reduced.
Hamilton, OntarioAges 18 years+ - NCT05496491Recruiting
Before-surgery radiation and chemo for rectal cancer
This study tests a specific “before surgery” treatment (radiation plus chemotherapy), followed by more chemotherapy to improve outcomes in people with certain types of rectal cancer. You might be considered if your cancer is locally advanced but not spread to distant organs.
LarissaAges 18–80 - NCT05501834Enrolling by invitation
Anxiety study for kids getting arm pins removed
This study tests if a child life specialist can help reduce anxiety when children have pins removed from their arm after a fracture. If your child is between 3 and 10, had a specific arm fracture treated with pins at Boston Children's Hospital, and speaks English, they may be eligible.
Boston, MassachusettsAges 3–10 - NCT05415384Recruiting
Cryotherapy plus surgery for broken ribs
This trial tests whether adding cryotherapy (freezing treatment to the injury area) to standard surgery for broken, displaced ribs can improve recovery. It’s for adults with multiple broken ribs who are getting a surgical stabilization procedure soon after injury.
Winston-Salem, North CarolinaAges 18–80 - NCT05361811Recruiting
Therapy coaching for parents of children with rare genetic syndromes
This trial tests an “Acceptance and Commitment Therapy” program for parents or legal guardians who feel moderate parenting stress. It aims to help caregivers cope in healthier ways and may also improve how they manage stress while supporting their child.
Bethesda, MarylandAges 18 years+ - NCT05142683Recruiting
Test an integrated care plan for teens with depression
This study tests whether a structured, coordinated care pathway helps teens (and their caregivers) manage depression better than usual care. It aims to see if targeted treatment and follow-up improve depression symptoms over time.
Toronto, OntarioAges 13–18 - NCT05109689Enrolling by invitation
ACT-P or T4C support programs after community reentry
This study compares two different programs meant to help people adjust when they return to the community. If you’re considered medium-to-high risk, you may be offered one program at random to see which works better for reducing problems and supporting successful reentry.
Fort Dodge, IowaAges 18 years+ - NCT05053867RecruitingPhase 3
Inhaled drug to treat lung bleeding in ventilated cancer patients
This Phase 3 study tests whether inhaled tranexamic acid can reduce lung bleeding (pulmonary hemorrhage) in people with cancer who are on a breathing machine. If you qualify, you may receive the study drug to help stop bleeding in the lungs.
Houston, TexasAges 18 years+ - NCT04823299Recruiting
Atrial fibrillation ablation using two different energy types
This trial tests whether one ablation approach works better than another for paroxysmal (intermittent) atrial fibrillation by targeting the heart’s “triggers” and “substrate” (where the rhythm problem is). If you qualify, you’ll be randomly assigned to one of two ablation energy methods during a pulmonary vein isolation procedure.
Ottawa, OntarioAges 18 years+ - NCT04697823Recruiting
Hyaluronan added to IVF fluid to help ongoing pregnancy rates
This study tests whether adding hyaluronan (a substance found naturally in the body) to IVF lab fluid can help more people achieve a pregnancy that is still ongoing after treatment. It is focused on people having a second or third egg retrieval after not becoming pregnant previously.
LeuvenAges 18–40 - NCT04429607Enrolling by invitationPhase 2
Testing different lasers for facial oil gland overgrowth
This study compares two types of laser treatments to see which works best for sebaceous hyperplasia (enlarged oil glands that can cause small bumps on the skin). If you are an adult getting cosmetic treatment for this condition, your results and possible side effects may help guide better future care.
Chicago, IllinoisAges 18 years+ - NCT04472702Recruiting
Ultrasound vs X-ray guidance for knee pain ablation
This trial compares two ways (ultrasound or X-ray guidance) to place a treatment for painful knee arthritis. It aims to see whether one guidance method works as well as the other for reducing knee pain.
Sacramento, CaliforniaAges 35–99 - NCT03716167Recruiting
Near-infrared laser for healing and pain in leg vein ulcers
This study tests whether a near-infrared laser can improve healing and reduce pain in chronic venous leg ulcers. If you qualify, you may receive laser treatment and will be checked over time for wound healing and pain levels.
Winston-Salem, North CarolinaAges 18 years+ - NCT03887715Recruiting
VNS device for long-term depression that hasn’t improved
This trial studies whether a vagus nerve stimulation (VNS) device can reduce symptoms of treatment-resistant depression. Participants either receive the VNS treatment or a no-stimulation control, to compare safety and effectiveness.
Birmingham, AlabamaAges 18 years+ - NCT07571837Recruiting
Nano-medication to reduce inflammation after root canal retreat
This study tests a special nano-sized (extremely tiny) medication placed inside a tooth after a previous root canal treatment failed. The goal is to reduce inflammation and swelling in the bone around the tooth's tip so it can heal better.
Cairo, Nasr CityAges 20–40 - NCT03671252RecruitingPhase 3
Chemotherapy before surgery for rectal cancer vs chemo with radiation
This Phase 3 trial compares two treatment plans given before rectal surgery. It tests whether stronger chemotherapy alone works better than chemotherapy pills plus long-term radiation to improve outcomes for locally advanced rectal cancer.
Guangzhou, GuangdongAges 18–75 - NCT07813767RecruitingPhase 3
Early antibiotic treatment guided by a blood test to prevent severe infection
This study tests whether giving an early antibiotic (meropenem) based on a new blood test (PSP) can prevent serious infections (sepsis) in people who come to the emergency department with signs of infection. The goal is to find out if this approach helps them get better faster and avoid more severe illness.
Athens, AtticaAges 18 years+ - NCT07755774Recruiting
Mindfulness and emotion skills for teens who self-injure
This study tests a therapy program that helps teens manage difficult emotions and reduce self-injury. A parent also takes part in a separate program to support the teen.
StockholmAges 12–17 - NCT07747909Recruiting
Orlistat for metabolic and hormonal health in PCOS
This study tests whether the weight-loss drug orlistat can improve blood sugar, hormones, and other metabolic measures in women with polycystic ovary syndrome (PCOS). If you have PCOS and are overweight, this treatment might help with symptoms like irregular periods and excess hair growth.
Abbottābād, Khyber PakhtunkhwaAges 18–45 - NCT06653868Recruiting
Sticky bone grafts for front tooth implants
This trial tests two different types of sticky bone graft materials placed around a dental implant right after a tooth is removed. It aims to see which type helps the bone heal better around the implant in the front of your mouth.
CairoAges 20–50 - NCT07611474Recruiting
Testing a treatment to prevent uterine scar tissue after surgery
This trial tests a new product designed to prevent scar tissue (adhesions) from forming inside the uterus after surgery. If you have uterine scar tissue causing fertility problems or irregular periods, this study may help determine if the treatment is safe and effective.
Changsha, HunanAges 20–40 - NCT07442162Enrolling by invitationPhase 1/Phase 2
Melatonin for excessive crying in newborns
This trial tests if melatonin can help reduce excessive crying in otherwise healthy newborns. It may offer a safe option for babies who cry for more than 3 hours a day on more than 3 days a week.
Mosul, Nineveh GovernorateAges 2 weeks–4 weeks
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Common questions
- Are there clinical trials for randomized controlled trial?
- Yes. Clin2 currently lists 602 recruiting randomized controlled trial studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a randomized controlled trial trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a randomized controlled trial trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.