Clinical trials
Real World Study clinical trials
Below are recruiting real world study clinical trials, each written for real people, not researchers. We’re tracking 353 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06767436Recruiting
Real-world study of Enhertu for advanced gastric cancer
This study looks at how well the drug Trastuzumab Deruxtecan works and how safe it is in real-world patients with advanced stomach or gastroesophageal cancer whose tumors are HER2-positive. The goal is to gather more information beyond what was learned in clinical trials.
Seoul, SeoulAges 19 years+ - NCT06988618Recruiting
Real-world use of nemolizumab for adults with prurigo nodularis
This study looks at how well nemolizumab works in real-world settings for adults with moderate-to-severe prurigo nodularis, a skin condition that causes intense itching and bumps. If you are starting this medication as part of your normal care, you may be able to join.
Birmingham, AlabamaAges 18 years+ - NCT06526078Enrolling by invitation
Combining brain training with ketamine for depression
This study tests if adding computer-based cognitive training to ketamine treatment can improve mood in people with depression that hasn't responded to other treatments. It aims to see if the combination works better than ketamine alone.
Oakland, CaliforniaAges 18–80 - NCT06491862Recruiting
Lung cancer care after chemo in Brazil
This study looks at how doctors in Brazil treat non-squamous non-small cell lung cancer after platinum chemotherapy stops working. It aims to understand real-world outcomes and help improve future care.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT06487078Recruiting
Study of Lorlatinib for untreated ALK-positive lung cancer
This study looks at how well and how safely the drug lorlatinib works in people with a certain type of advanced lung cancer (ALK-positive NSCLC) who have not had treatment for their advanced cancer yet. The goal is to see how effective it is in the real world.
Paris, ParisAges 18 years+ - NCT07744711Enrolling by invitation
Testing a light therapy app on an iPad
This study tests an iPad app that provides light therapy, which may help with conditions like seasonal depression or sleep problems. You will use the app for a period of time, and you may also choose to provide blood samples for a biomarker sub-study.
New York, New YorkAges 18 years+ - NCT06923774Recruiting
Registry study for lung biopsy with Ion system
This study collects information from patients having a lung biopsy or nodule localization using the Ion endoluminal system. It aims to understand how well the system works in real-world settings.
Le Plessis-RobinsonAges 18 years+ - NCT07442045Recruiting
Comparing combined vs single drug for ulcerative colitis
Researchers want to see if taking two medications together (upadacitinib and vedolizumab) works better than taking just upadacitinib alone for people with moderate to severe ulcerative colitis. This is a real-world study, meaning it looks at patients being treated in normal medical practice.
Foshan, GuangdongAges 18 years+ - NCT06745882RecruitingPhase 2
Pembrolizumab for Black Patients with Advanced Lung Cancer
This study tests if the drug pembrolizumab (Keytruda), alone or with chemotherapy, works well for Black patients with advanced non-small cell lung cancer (NSCLC) who haven't had treatment yet. The goal is to see real-world results in this group.
Tampa, FloridaAges 18 years+ - NCT07599904Recruiting
Real-world study of Medtronic stroke treatment devices
This registry tracks how Medtronic's FDA-approved devices work in treating acute ischemic stroke (a type of stroke caused by a blood clot) in everyday clinical practice. Researchers collect information to understand device safety and effectiveness outside of formal clinical trials.
Flint, MichiganAges 18 years+ - NCT06899204Recruiting
Abrocitinib for atopic dermatitis after biologic therapy
This study looks at how well abrocitinib (a daily pill) works for people with moderate to severe eczema who have already tried biologic medicines and didn't get enough relief. It aims to see if this treatment can help you better manage your eczema.
San Diego, CaliforniaAges 12 years+ - NCT04526093Recruiting
Study of medical cannabis using patient symptom reports
This study looks at how medical cannabis affects symptoms like pain, epilepsy, sleep, and anxiety or depression, based on what patients report over time. It may help researchers understand what works in real life when people use verified medical cannabis products.
Toronto, OntarioAges 19 years+ - NCT07091019Recruiting
CML patient experience study on standard TKI therapy
This study tracks the experiences and health outcomes of people with chronic myeloid leukemia (CML) who are taking approved first or second line tyrosine kinase inhibitor (TKI) medicines. It helps doctors learn how these treatments work in everyday care.
Birmingham, AlabamaAges 18–100 - NCT07435649Recruiting
New test for finding germs in spinal fluid during brain infections
This study tests a new type of test called Delve Detect that looks for germs in spinal fluid from people suspected of having a brain or spinal cord infection. It helps doctors find the cause faster and more accurately.
San Francisco, CaliforniaAges Any age - NCT04914611Recruiting
Real-world study of chronic hepatitis B care in Australia
This study looks at people who have long-term hepatitis B and how they receive care in Australia. It may help improve understanding of what’s working in real life for patients like you.
Sydney, New South WalesAges 18 years+ - NCT07243002Recruiting
Patient outcomes with ribociclib or abemaciclib for early breast cancer
This study looks at how women and men with stage II or III HR+ HER2- breast cancer do when they start treatment with ribociclib or abemaciclib (combined with hormone therapy) after surgery. Researchers want to understand real-world experiences and results.
LondonAges 18 years+ - NCT06517719Recruiting
Real-world study of Pluvicto for advanced prostate cancer
This study looks at how men with advanced prostate cancer (mCRPC) do when they receive a treatment called Pluvicto (lutetium vipivotide tetraxetan) in real-world settings. It aims to collect information on treatment effectiveness and quality of life without adding any extra procedures or medications.
Konstanz, Baden-WurttembergAges 18–99 - NCT06725030Recruiting
Robotic surgery for lymphedema (Symani System)
This trial uses a robotic arm called Symani to help surgeons perform more precise microsurgery (working on tiny blood vessels and lymph channels). It is for adults with moderate lymphedema in one arm or leg who have already tried standard lymphedema therapy and still have swelling.
Beverly Hills, CaliforniaAges 22 years+ - NCT05093374RecruitingPhase 4
AI-guided care for wet age-related macular degeneration
This Phase 4 study tests an artificial-intelligence (AI) system used in real-world care for people with “wet” age-related macular degeneration. The goal is to help doctors monitor and treat the eye more accurately and safely over time.
Vienna, State of ViennaAges 50–100 - NCT05145478Recruiting
Real-world outcomes after Shockwave treatment for blocked leg artery
This study follows what happens in real life after using Shockwave’s device (intravascular lithotripsy) to treat a hard, calcified blockage in the common femoral artery, then completing standard treatment. It may help doctors understand which patients benefit and what results to expect.
New Haven, ConnecticutAges 18 years+ - NCT05550961Recruiting
Real-world study of innovative treatments for lung cancer
This study collects real-world information about people with lung cancer who get newer kinds of cancer drugs. It aims to understand how these innovative therapies work in everyday care and help future research.
MilanAges 18 years+ - NCT05557487Recruiting
Real-world low-dose CT screening for people at high lung risk
This study looks at how people at high risk for lung cancer use low-dose CT scans in real life, and what outcomes happen over time. It may help confirm which groups benefit most from regular screening and support safer screening decisions.
Taichung, TaiwanAges 20–80 - NCT05845255Recruiting
Test wearable monitoring for epilepsy quality of life and safety
This study tests a wearable device that records seizure-related information to understand how epilepsy affects daily life and safety. It may help your care team better track seizures in real-world settings and understand quality-of-life changes.
KorkAges 12–65 - NCT05879757Recruiting
Real-world HyQvia use for adults with myeloma and weak immunity
This study looks at how HyQvia (an immune-boosting medicine given under the skin) is used in real life for adults with multiple myeloma and secondary immune problems. It may help doctors understand what works best and how patients do when HyQvia is used routinely.
CórdobaAges 18 years+
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Common questions
- Are there clinical trials for real world study?
- Yes. Clin2 currently lists 353 recruiting real world study studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a real world study trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a real world study trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.