Clinical trials
Rejection clinical trials
Below are recruiting rejection clinical trials, each written for real people, not researchers. We’re tracking 103 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04707872Recruiting
Study of a blood test after heart transplant
This study checks whether a special blood test can help detect heart transplant rejection or problems by comparing it to biopsy results. It may help your care team monitor your transplant with less guesswork.
Little Rock, ArkansasAges Any age - NCT05655273Enrolling by invitationPhase 4
Switch tacrolimus timing after liver transplant to Envarsus
This trial looks at whether changing your maintenance anti-rejection medicine from Prograf (usually twice daily) to Envarsus (once daily) can help keep your liver and kidney function stable. It targets people who may be having kidney side effects, symptoms from tacrolimus, or trouble taking a twice-daily medicine.
Toronto, OntarioAges 18–99 - NCT04582279Recruiting
Lung ultrasound test to rule out rejection after lung transplant
This study checks whether a painless lung ultrasound can help tell when rejection is unlikely after a lung transplant. If it works, it could reduce the need for other tests in people who feel well.
Jacksonville, FloridaAges 18 years+ - NCT04526431Recruiting
Tacrolimus dose study in early kidney transplant patients
This study looks at how tacrolimus (a rejection-preventing medicine) should be dosed in the first days to years after a kidney transplant. It may help personalize dosing by comparing different patient groups, including using genetic testing.
Grenoble, Auvergne-Rhône-AlpesAges 18 years+ - NCT04239703Recruiting
Kidney transplant biopsy study using blood test clues
This study looks at kidney transplant patients who are getting a kidney biopsy for usual clinical reasons. It tests whether special blood test results (from a sample taken as part of the study) can help spot transplant kidney problems earlier or more accurately.
Tampa, FloridaAges Any age - NCT03102125RecruitingPhase 4
Testing causes of heart transplant graft problems with scans
This study looks at why heart transplant “grafts” can start to malfunction again after transplant. If you qualify, you may undergo MRI and related heart testing to help researchers find ways to detect or understand graft dysfunction.
La Jolla, CaliforniaAges 18 years+ - NCT02812290Recruiting
Microarray testing during lung transplant biopsy
This study looks at using a special lab test (microarrays) on tissue taken during a lung transplant biopsy. It aims to learn how the test may help doctors better diagnose and guide care after transplant.
Phoenix, ArizonaAges 18 years+ - NCT06342128Recruiting
Molecular study of inflammation in kidney transplants
This study looks at molecular changes in kidney transplants that have microvascular inflammation (a type of injury). It aims to better understand why some transplants get this inflammation, which could lead to better treatments.
ParisAges 18–100 - NCT07079735RecruitingPhase 2/Phase 3
Preventing CMV after heart transplant
This trial compares two antiviral drugs, valganciclovir and letermovir, to see which works better at preventing CMV infection after a heart transplant. If you've had a heart transplant and haven't started preventive treatment yet, this study may be for you.
New York, New YorkAges 18–99 - NCT06794970Recruiting
Tissue study for chronic kidney transplant rejection
This study looks at tissue samples from kidney transplant patients who have a specific type of long-term rejection called chronic active humoral rejection (cAMR). It aims to better understand the condition and help future patients.
Bologna, BOAges 18 years+ - NCT06082037RecruitingPhase 3
Testing belumosudil for chronic lung allograft dysfunction after transplant
This trial tests an oral medication called belumosudil for people with chronic lung allograft dysfunction (CLAD) after a double lung transplant. It may help slow the decline in lung function.
Birmingham, AlabamaAges 18 years+ - NCT06314230Recruiting
Genomics of chronic kidney transplant failure study
This study looks at how genes affect long-term kidney transplant health. It aims to understand why some transplanted kidneys fail over time, and may help personalize care for transplant recipients.
Westmead, New South WalesAges 18–75 - NCT06656065Recruiting
Heart artery check after transplant
This study tests a new way to check the health of the arteries in your new heart after transplant. It uses a special medication (adenosine) to see how well blood flows through the heart's arteries, which could help doctors find problems early.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT07508787RecruitingPhase 2
Study comparing siplizumab to another drug for kidney transplant acceptance
This trial tests a new drug, siplizumab, to see if it helps the body accept a donated kidney better than a standard treatment. It is for people receiving a kidney transplant from a living or deceased donor.
Atlanta, GeorgiaAges 18–70 - NCT07412470RecruitingPhase 2/Phase 3
Testing frexalimab vs tacrolimus for new kidney transplant patients
This trial compares a new drug called frexalimab to the standard drug tacrolimus in people who are getting their first kidney transplant. The goal is to see if frexalimab works better and has a safer side effect profile.
Boston, MassachusettsAges 18–70 - NCT06514378RecruitingPhase 1
Safety of stem cells for chronic lung transplant rejection
This trial tests whether a single dose of stem cells given through a bronchoscope is safe for people whose lungs are failing after a transplant. It may help those with a condition called bronchiolitis obliterans syndrome (BOS), a type of chronic rejection that makes it harder to breathe.
MadridAges 18 years+ - NCT06817993Recruiting
How social media affects the teen brain
This study looks at how social media affects the brains of teens with depression. You would complete smartphone surveys and have one brain scan (MRI) to help researchers understand these connections.
Pittsburgh, PennsylvaniaAges 13–17 - NCT03707262RecruitingPhase 1/Phase 2
Brother or sister donor transplant using kidney and stem cells
This study tests a combined approach for kidney transplant patients: standard living-donor kidney transplant plus an added “stem cell” component taken from the same sibling donor. It aims to improve transplant outcomes by trying to better control the immune response and reduce complications.
Los Angeles, CaliforniaAges 18 years+ - NCT06679257Recruiting
Liquid biopsy for lung transplant damage classification
This study tests a simple blood test (liquid biopsy) to detect and classify damage to a transplanted lung. It aims to find signs of rejection or injury earlier, which could help doctors treat problems sooner.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT06717542Recruiting
Liver tissue analysis to predict transplant success
This study looks at liver tissue before transplantation to find ways to predict how well the transplant will work. It involves a special treatment called HOPE to help preserve the liver.
BolognaAges 18 years+ - NCT06557564Recruiting
Liver transplant biopsy study using TruGraf
This study uses a blood test called TruGraf to check for liver transplant problems. It may help diagnose issues without a biopsy.
Toronto, OntarioAges 18 years+ - NCT07244419RecruitingEarly Phase 1
Preventing stem cell transplant rejection in children
This early-phase trial tests a medication to prevent rejection of donated stem cells in children. It's for patients who are at high risk for their transplant to fail.
Cincinnati, OhioAges Any age - NCT06997471RecruitingPhase 1
Safety of modified stem cell infusion with organ transplant
This early-phase trial tests whether it is safe to give a special type of stem cell transplant (with the naïve T cells removed and only memory T cells left) to people receiving organ transplants. It is for children getting intestine or lung transplants, and for children or adults getting kidney transplants.
Madrid, MadridAges birth+ - NCT03321656RecruitingPhase 2/Phase 3
Envarsus XR after kidney transplant to reduce hidden rejection
This study looks at whether Envarsus XR helps prevent “subclinical” (not obviously noticeable) kidney transplant rejection by changing blood immune test results. You may be able to join if you recently received a kidney transplant and can take the study medicine as required.
Lexington, KentuckyAges 18–75
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Common questions
- Are there clinical trials for rejection?
- Yes. Clin2 currently lists 103 recruiting rejection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rejection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rejection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.